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Overview

ID MAG04057
Name TLS3_bin.43
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota
Class Bacteroidia
Order Flavobacteriales
Family Crocinitomicaceae
Genus UBA4466
Species
Assembly information
Completeness (%) 82.2
Contamination (%) 1.2
GC content (%) 45.0
N50 (bp) 9,115
Genome size (bp) 3,692,132

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3166

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1019920_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 9.742e-227 707.0
TLS3_k127_1019920_1 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K00012 - 1.1.1.22 7.383e-216 676.0
TLS3_k127_1019920_10 membrane - - - 0.0000000000000000000001834 99.0
TLS3_k127_1019920_2 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 596.0
TLS3_k127_1019920_3 Oxidoreductase family, C-terminal alpha beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 555.0
TLS3_k127_1019920_4 sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 542.0
TLS3_k127_1019920_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 511.0
TLS3_k127_1019920_6 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 370.0
TLS3_k127_1019920_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 338.0
TLS3_k127_1019920_8 PFAM Bacterial transferase hexapeptide (three repeats) K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 330.0
TLS3_k127_1019920_9 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000005454 265.0
TLS3_k127_1035743_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1645.0
TLS3_k127_1035743_1 PFAM Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003419 285.0
TLS3_k127_1035743_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000002715 176.0
TLS3_k127_1035743_3 Fungalysin metallopeptidase (M36) - - - 0.000000001436 72.0
TLS3_k127_1035743_4 SprB repeat - - - 0.0000002704 64.0
TLS3_k127_1035743_5 - - - - 0.00008974 52.0
TLS3_k127_1044405_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 425.0
TLS3_k127_1044405_1 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 335.0
TLS3_k127_1093641_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1116.0
TLS3_k127_1093641_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 485.0
TLS3_k127_1093641_2 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000002268 180.0
TLS3_k127_1093641_3 metallopeptidase activity K01337 - 3.4.21.50 0.00000000000000000000001832 100.0
TLS3_k127_1112805_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1168.0
TLS3_k127_1112805_1 Hep Hag repeat protein - - - 2.269e-291 923.0
TLS3_k127_1112805_2 von Willebrand factor (vWF) type A domain - - - 4.372e-211 676.0
TLS3_k127_1112805_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 581.0
TLS3_k127_1112805_4 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 378.0
TLS3_k127_1112805_5 atp-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 284.0
TLS3_k127_1112805_6 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000002856 178.0
TLS3_k127_1112805_8 Metallo-peptidase family M12B Reprolysin-like - - - 0.00008494 56.0
TLS3_k127_1162205_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004316 282.0
TLS3_k127_1162205_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000713 174.0
TLS3_k127_1162205_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000003673 181.0
TLS3_k127_1162205_3 amine dehydrogenase activity K00504 - 1.14.17.3 0.0000000000000000000000000000000000003158 160.0
TLS3_k127_1162205_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000001092 136.0
TLS3_k127_1162205_5 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000002371 123.0
TLS3_k127_1189648_0 Large family of predicted nucleotide-binding domains K07175 - - 7.685e-216 677.0
TLS3_k127_1189648_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000002056 178.0
TLS3_k127_1189648_3 Domain of unknown function (DU1801) - - - 0.000009213 52.0
TLS3_k127_120086_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.446e-306 949.0
TLS3_k127_120086_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000721 141.0
TLS3_k127_1216979_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 410.0
TLS3_k127_1216979_1 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 363.0
TLS3_k127_1216979_2 Protein of unknown function (DUF4255) - - - 0.0000006117 58.0
TLS3_k127_1233627_0 GH3 auxin-responsive promoter - - - 2.895e-199 629.0
TLS3_k127_1233627_1 GDP-mannose 4,6 dehydratase K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 489.0
TLS3_k127_1233627_2 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 384.0
TLS3_k127_1233627_3 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 362.0
TLS3_k127_1233627_4 - - - - 0.000000000000000000000000000000000000005524 149.0
TLS3_k127_1233627_5 SPTR Cell surface protein K01186 - 3.2.1.18 0.00000000000000000000000001304 128.0
TLS3_k127_1236316_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 464.0
TLS3_k127_1236316_1 Calcineurin-like phosphoesterase - - - 0.0000009545 60.0
TLS3_k127_1267952_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 294.0
TLS3_k127_1267952_1 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
TLS3_k127_1267952_2 - - - - 0.00000000000000000000000000000001414 132.0
TLS3_k127_1267952_3 - - - - 0.00000000000000000000000000000003889 140.0
TLS3_k127_1267952_4 Domain of unknown function (DUF2520) - - - 0.0000001465 53.0
TLS3_k127_1277407_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1212.0
TLS3_k127_1277407_1 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 520.0
TLS3_k127_1277407_2 Protein of unknown function (DUF3347) K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 374.0
TLS3_k127_1277407_3 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 312.0
TLS3_k127_1277407_4 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002254 274.0
TLS3_k127_1277407_5 Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004457 260.0
TLS3_k127_1277407_6 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
TLS3_k127_1277407_7 Multicopper oxidase - - - 0.0000000000000000000000001401 107.0
TLS3_k127_1277407_8 SPTR Cell surface protein - - - 0.0000000000005699 74.0
TLS3_k127_1277407_9 Esterase PHB depolymerase - - - 0.000458 48.0
TLS3_k127_1299793_0 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 476.0
TLS3_k127_1299793_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 361.0
TLS3_k127_1299793_2 SPTR Cell surface protein K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002012 271.0
TLS3_k127_1299793_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003163 229.0
TLS3_k127_1299793_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000004608 243.0
TLS3_k127_1299793_5 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000001094 98.0
TLS3_k127_1299793_7 Zinc metalloprotease (Elastase) - - - 0.0000000003281 73.0
TLS3_k127_1306737_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.12e-310 970.0
TLS3_k127_1306737_1 C-terminal domain of CHU protein family - - - 5.497e-300 948.0
TLS3_k127_1306737_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000009422 208.0
TLS3_k127_1306737_11 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000002129 184.0
TLS3_k127_1306737_12 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000001132 180.0
TLS3_k127_1306737_13 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000005436 160.0
TLS3_k127_1306737_14 Sporulation related domain - - - 0.00000000000000000000000000000000000000004514 168.0
TLS3_k127_1306737_15 OmpA family - - - 0.00000000000000000000000000000005331 141.0
TLS3_k127_1306737_16 - - - - 0.0000000000000000000000004926 110.0
TLS3_k127_1306737_17 Domain of unknown function (DUF4856) - - - 0.000776 48.0
TLS3_k127_1306737_2 PFAM von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 583.0
TLS3_k127_1306737_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 569.0
TLS3_k127_1306737_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 544.0
TLS3_k127_1306737_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 546.0
TLS3_k127_1306737_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 466.0
TLS3_k127_1306737_7 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 470.0
TLS3_k127_1306737_8 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 441.0
TLS3_k127_1306737_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 367.0
TLS3_k127_1318297_0 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 557.0
TLS3_k127_1318297_1 Peptidase m28 - - - 0.00000000000000000000000000000000000002632 154.0
TLS3_k127_1318297_2 - - - - 0.0000000000000000000002908 100.0
TLS3_k127_1318297_3 S-adenosyl-l-methionine hydroxide adenosyltransferase - - - 0.00000000000000005309 83.0
TLS3_k127_132218_0 Domain of unknown function (DUF5117) - - - 1.2e-293 924.0
TLS3_k127_132218_1 TonB-dependent receptor - - - 9.985e-292 914.0
TLS3_k127_1326659_0 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 579.0
TLS3_k127_1326659_1 membrane K03748 - - 0.000000000000000000000000000000000000000000000000000000000796 208.0
TLS3_k127_1333925_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1446.0
TLS3_k127_1333925_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1091.0
TLS3_k127_1333925_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000007896 200.0
TLS3_k127_1333925_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000007378 178.0
TLS3_k127_1333925_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000006254 165.0
TLS3_k127_1333925_13 Polymer-forming cytoskeletal - - - 0.0000000000000000000000001985 110.0
TLS3_k127_1333925_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000003616 97.0
TLS3_k127_1333925_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000001733 78.0
TLS3_k127_1333925_16 - - - - 0.0000000000001879 75.0
TLS3_k127_1333925_17 Parallel beta-helix repeats - - - 0.00006627 54.0
TLS3_k127_1333925_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.438e-307 945.0
TLS3_k127_1333925_3 Tetratricopeptide repeats - - - 2.684e-264 840.0
TLS3_k127_1333925_4 Saccharopine dehydrogenase C-terminal domain K00290,K00293 - 1.5.1.10,1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 577.0
TLS3_k127_1333925_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 514.0
TLS3_k127_1333925_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 409.0
TLS3_k127_1333925_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 384.0
TLS3_k127_1333925_8 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 369.0
TLS3_k127_1333925_9 Protein of unknown function (DUF3137) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
TLS3_k127_1363779_0 Peptidase family M49 K01277 - 3.4.14.4 1.617e-305 951.0
TLS3_k127_1363779_1 Phosphorylase superfamily K01241 - 3.2.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 439.0
TLS3_k127_1363779_2 - - - - 0.0000000000000000000000000000000000003873 143.0
TLS3_k127_1363779_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000009634 122.0
TLS3_k127_1363779_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000001625 103.0
TLS3_k127_1363779_5 P53-induced protein with a death domain K10130 GO:0000075,GO:0000077,GO:0000278,GO:0003674,GO:0005102,GO:0005123,GO:0005126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0006355,GO:0006919,GO:0006950,GO:0006974,GO:0006977,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007346,GO:0008150,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010948,GO:0010950,GO:0010952,GO:0012505,GO:0019219,GO:0019222,GO:0022402,GO:0023051,GO:0023052,GO:0023056,GO:0030162,GO:0030330,GO:0031323,GO:0031325,GO:0031326,GO:0031570,GO:0031571,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032813,GO:0033554,GO:0035556,GO:0042770,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043280,GO:0043281,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044773,GO:0044774,GO:0044783,GO:0044819,GO:0045786,GO:0045787,GO:0045862,GO:0045930,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051336,GO:0051345,GO:0051716,GO:0051726,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0071156,GO:0071158,GO:0072331,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0090068,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902041,GO:1902043,GO:1902400,GO:1902402,GO:1902403,GO:1902806,GO:1902807,GO:1903047,GO:1903506,GO:2000045,GO:2000112,GO:2000116,GO:2000134,GO:2001056,GO:2001141,GO:2001233,GO:2001235,GO:2001236,GO:2001238 - 0.00000000007709 66.0
TLS3_k127_1366257_0 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
TLS3_k127_1366257_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
TLS3_k127_1366257_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000001354 217.0
TLS3_k127_1366257_3 Pkd domain containing protein - - - 0.000000000000000000000000001099 120.0
TLS3_k127_1374591_0 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 559.0
TLS3_k127_1374591_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 519.0
TLS3_k127_1374591_2 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 492.0
TLS3_k127_1374591_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 379.0
TLS3_k127_1374591_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000005094 226.0
TLS3_k127_1374591_5 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000003058 210.0
TLS3_k127_1423975_0 Type IV secretion-system coupling protein DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 327.0
TLS3_k127_1423975_1 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 301.0
TLS3_k127_1423975_10 - - - - 0.0000000000204 67.0
TLS3_k127_1423975_13 - - - - 0.000000005087 64.0
TLS3_k127_1423975_14 - - - - 0.00002309 55.0
TLS3_k127_1423975_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0003525 44.0
TLS3_k127_1423975_2 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000008962 265.0
TLS3_k127_1423975_3 - - - - 0.000000000000000000000000000000000000000000000000000000001987 203.0
TLS3_k127_1423975_4 RadC-like JAB domain - - - 0.00000000000000000000000000000000004791 139.0
TLS3_k127_1423975_6 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000003312 130.0
TLS3_k127_1423975_7 - - - - 0.00000000000000007055 88.0
TLS3_k127_1423975_8 - - - - 0.0000000000000002948 85.0
TLS3_k127_1423975_9 Belongs to the 'phage' integrase family - - - 0.0000000000001566 81.0
TLS3_k127_1424535_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.57e-200 629.0
TLS3_k127_1424535_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000002966 154.0
TLS3_k127_1424535_3 - - - - 0.0007427 42.0
TLS3_k127_143430_0 Aromatic amino acid lyase K01745 - 4.3.1.3 1.031e-221 697.0
TLS3_k127_143430_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 2.646e-205 649.0
TLS3_k127_143430_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 465.0
TLS3_k127_143430_3 - - - - 0.00000000000000000000000000000000000000000000000000003981 195.0
TLS3_k127_1453145_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 490.0
TLS3_k127_1453145_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 487.0
TLS3_k127_1453145_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004068 210.0
TLS3_k127_1453145_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000002991 170.0
TLS3_k127_1453145_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001125 155.0
TLS3_k127_1453145_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000001638 155.0
TLS3_k127_1453145_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002629 150.0
TLS3_k127_1453145_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001441 144.0
TLS3_k127_1453145_16 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000003068 126.0
TLS3_k127_1453145_17 TIGRFAM ribosomal protein L30, bacterial organelle K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000121 83.0
TLS3_k127_1453145_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001878 80.0
TLS3_k127_1453145_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 419.0
TLS3_k127_1453145_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 314.0
TLS3_k127_1453145_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 296.0
TLS3_k127_1453145_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
TLS3_k127_1453145_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004232 256.0
TLS3_k127_1453145_7 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000258 229.0
TLS3_k127_1453145_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001601 213.0
TLS3_k127_1453145_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003773 211.0
TLS3_k127_1462804_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 477.0
TLS3_k127_1462804_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.00000000000000000000001172 115.0
TLS3_k127_1462804_2 surface antigen - - - 0.0000000000000002265 93.0
TLS3_k127_1533321_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0 1273.0
TLS3_k127_1533321_1 LVIVD repeat - - - 2.137e-224 719.0
TLS3_k127_1533321_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 516.0
TLS3_k127_1533321_3 MORN repeat variant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
TLS3_k127_1533321_4 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000003819 196.0
TLS3_k127_1533321_5 - - - - 0.000000000000000000000000000000000000000000003553 172.0
TLS3_k127_1533321_6 Thioredoxin - - - 0.0000000000000000000000000000000000004988 144.0
TLS3_k127_1533321_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000008876 117.0
TLS3_k127_1548461_0 COG3621 Patatin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 428.0
TLS3_k127_1551158_0 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000005586 215.0
TLS3_k127_1551158_1 Histidine kinase - - - 0.00000000000000000000000000000000001279 146.0
TLS3_k127_1551158_2 - - - - 0.000000000000000000000000005814 118.0
TLS3_k127_1553275_0 PFAM Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 1.829e-212 674.0
TLS3_k127_1553275_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 590.0
TLS3_k127_1553275_2 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 534.0
TLS3_k127_1553275_3 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 508.0
TLS3_k127_1553275_4 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
TLS3_k127_1553275_6 lysine biosynthetic process via aminoadipic acid K00997,K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.8.7 0.00007083 53.0
TLS3_k127_1580828_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 433.0
TLS3_k127_1580828_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 301.0
TLS3_k127_1580828_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
TLS3_k127_1580828_3 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000006453 241.0
TLS3_k127_1580828_4 TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000002751 235.0
TLS3_k127_1580828_5 GH3 auxin-responsive promoter - - - 0.0000000000000000001041 90.0
TLS3_k127_1580828_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000004111 79.0
TLS3_k127_1583499_0 TIGRFAM ATP-binding cassette protein, ChvD family K15738 - - 0.0 1004.0
TLS3_k127_1583499_1 Peptidase family M1 domain - - - 1.738e-244 760.0
TLS3_k127_1583499_10 - - - - 0.000000000000002389 79.0
TLS3_k127_1583499_11 - - - - 0.000000000000004139 81.0
TLS3_k127_1583499_12 - - - - 0.0000000000007177 75.0
TLS3_k127_1583499_13 Protein of unknown function (DUF2752) - - - 0.0000000000008214 71.0
TLS3_k127_1583499_2 PFAM Peptidase family M20 M25 M40 K01270 - - 3.135e-210 662.0
TLS3_k127_1583499_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 569.0
TLS3_k127_1583499_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006274 229.0
TLS3_k127_1583499_5 conserved protein (DUF2132) - - - 0.00000000000000000000000214 104.0
TLS3_k127_1583499_6 Putative quorum-sensing-regulated virulence factor K09954 - - 0.000000000000000000000004265 102.0
TLS3_k127_1583499_8 helix-turn-helix domain protein - - - 0.000000000000000000001732 97.0
TLS3_k127_1589540_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
TLS3_k127_1589540_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 294.0
TLS3_k127_1589540_2 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000006201 177.0
TLS3_k127_1589540_3 - - - - 0.00000001159 64.0
TLS3_k127_1594744_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 579.0
TLS3_k127_1594744_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 484.0
TLS3_k127_1594744_10 Multicopper oxidase - - - 0.0000002502 61.0
TLS3_k127_1594744_11 Fibronectin type III domain - - - 0.0000008475 53.0
TLS3_k127_1594744_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 442.0
TLS3_k127_1594744_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
TLS3_k127_1594744_4 cytochrome C peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 308.0
TLS3_k127_1594744_5 Phosphoheptose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003186 236.0
TLS3_k127_1594744_7 Multicopper oxidase - - - 0.000000000000000000000000000000000000003976 161.0
TLS3_k127_1594744_9 - - - - 0.0000000000000000000000521 104.0
TLS3_k127_1609326_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1129.0
TLS3_k127_1609326_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 8.148e-222 698.0
TLS3_k127_1609326_2 - - - - 2.897e-212 665.0
TLS3_k127_1609326_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 546.0
TLS3_k127_1609326_4 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002202 244.0
TLS3_k127_1609326_5 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000006469 213.0
TLS3_k127_1609326_6 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000000006171 194.0
TLS3_k127_1613782_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 621.0
TLS3_k127_1613782_1 - - - - 0.00000000000000000000000000000000000004362 147.0
TLS3_k127_1613782_2 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000000003068 130.0
TLS3_k127_1613782_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000002744 111.0
TLS3_k127_1613782_4 metallopeptidase activity - - - 0.000000000000000000000003137 116.0
TLS3_k127_1628882_0 Phosphotransferase enzyme family - - - 0.0 1198.0
TLS3_k127_1628882_1 PFAM Polysaccharide biosynthesis protein - - - 5.723e-228 722.0
TLS3_k127_1628882_10 CYTH K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000005498 165.0
TLS3_k127_1628882_11 Domain of unknown function (DUF4369) - - - 0.000000000000000000000000000000000000002972 164.0
TLS3_k127_1628882_12 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000006478 154.0
TLS3_k127_1628882_13 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000001619 133.0
TLS3_k127_1628882_14 Plasmid stabilization system - - - 0.00000000000000000000000000007928 117.0
TLS3_k127_1628882_16 DUF218 domain - - - 0.00000000000000000000006779 100.0
TLS3_k127_1628882_17 - - - - 0.0000000000002976 82.0
TLS3_k127_1628882_2 Domain of unknown function (DUF3520) K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 575.0
TLS3_k127_1628882_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
TLS3_k127_1628882_4 MORN repeat variant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 299.0
TLS3_k127_1628882_5 PFAM O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 281.0
TLS3_k127_1628882_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 263.0
TLS3_k127_1628882_7 Galactose binding lectin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001718 250.0
TLS3_k127_1628882_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000005015 231.0
TLS3_k127_1628882_9 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
TLS3_k127_1629115_0 PFAM Signal transduction histidine kinase, internal region - - - 0.00000000000000000000000000000000000000000000000000000000000025 237.0
TLS3_k127_1629115_1 acetyltransferase - - - 0.00000000000007882 76.0
TLS3_k127_1634167_0 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 435.0
TLS3_k127_1634167_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 395.0
TLS3_k127_1634167_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 364.0
TLS3_k127_1634167_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000005014 223.0
TLS3_k127_1634167_4 - - - - 0.000000000000000000001012 105.0
TLS3_k127_1634167_5 peptidyl-prolyl isomerase K03769,K07533 - 5.2.1.8 0.00000001312 61.0
TLS3_k127_1638131_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 535.0
TLS3_k127_1638131_1 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 297.0
TLS3_k127_1638131_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000006862 219.0
TLS3_k127_1638131_3 PFAM Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000005663 174.0
TLS3_k127_1638131_4 3-oxoacyl-(ACP) synthase - - - 0.00000000000000000000000000000000000000000009747 165.0
TLS3_k127_1638131_5 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000001566 138.0
TLS3_k127_1638131_6 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000005674 131.0
TLS3_k127_1638131_7 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000004817 99.0
TLS3_k127_1639334_0 chitin binding K01183,K05989 - 3.2.1.14,3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 345.0
TLS3_k127_1639334_1 CbiX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 324.0
TLS3_k127_1639334_2 COG1520 FOG WD40-like repeat - - - 0.0001155 49.0
TLS3_k127_1639334_3 - - - - 0.0002339 51.0
TLS3_k127_16470_0 PD-(D/E)XK nuclease superfamily - - - 2.955e-210 682.0
TLS3_k127_16470_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 302.0
TLS3_k127_16470_2 TraB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002658 253.0
TLS3_k127_1667384_0 RHS repeat-associated core domain protein - - - 1.048e-245 805.0
TLS3_k127_1667384_1 Salmonella virulence plasmid 28.1kDa A protein - - - 0.0000000000000000000000000007447 122.0
TLS3_k127_1677868_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.238e-258 814.0
TLS3_k127_1677868_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 486.0
TLS3_k127_1677868_2 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 432.0
TLS3_k127_1677868_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 425.0
TLS3_k127_1677868_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000007747 238.0
TLS3_k127_1677868_5 6-phosphogluconolactonase activity K20276 - - 0.00003674 55.0
TLS3_k127_1692602_0 Transporter K02429 - - 4.234e-222 701.0
TLS3_k127_1692602_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.291e-212 677.0
TLS3_k127_1692602_10 PFAM PKD domain - - - 0.00000000000000000000000000003663 128.0
TLS3_k127_1692602_11 iron ion homeostasis K03709,K03711,K04758,K04759 GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874 - 0.0000000000001542 73.0
TLS3_k127_1692602_2 Aldehyde K13877,K14519 - 1.2.1.26,1.2.1.4 1.624e-203 646.0
TLS3_k127_1692602_3 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 546.0
TLS3_k127_1692602_4 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 536.0
TLS3_k127_1692602_5 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 456.0
TLS3_k127_1692602_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 370.0
TLS3_k127_1692602_7 TIGRFAM C-terminal peptidase (prc) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 375.0
TLS3_k127_1692602_8 Belongs to the proline racemase family K12658 - 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 301.0
TLS3_k127_1692602_9 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 295.0
TLS3_k127_1705029_0 soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 501.0
TLS3_k127_1705029_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
TLS3_k127_1705029_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 292.0
TLS3_k127_1705029_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
TLS3_k127_1706997_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 597.0
TLS3_k127_1706997_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 558.0
TLS3_k127_1706997_2 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 499.0
TLS3_k127_1706997_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 421.0
TLS3_k127_1706997_4 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 388.0
TLS3_k127_1706997_5 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006968 275.0
TLS3_k127_1706997_6 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 276.0
TLS3_k127_1706997_7 Haem-binding domain - - - 0.00000000000000000000000000000000000000000000000002218 183.0
TLS3_k127_1706997_8 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000000006343 87.0
TLS3_k127_1742853_0 Rhs element Vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000556 263.0
TLS3_k127_1742853_1 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000001433 120.0
TLS3_k127_1742853_2 homolog of phage Mu protein gp47 - - - 0.0000000000002416 74.0
TLS3_k127_1742853_3 PFAM PAAR motif - - - 0.0000000006385 63.0
TLS3_k127_174720_0 Mn2 and Fe2 transporters of the NRAMP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 483.0
TLS3_k127_174720_1 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 352.0
TLS3_k127_174720_2 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 347.0
TLS3_k127_174720_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
TLS3_k127_174720_4 PFAM Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007942 285.0
TLS3_k127_174720_5 DNA-binding ferritin-like protein (Oxidative damage protectant) K04047 - - 0.00000000000000000000000000000000000000000000000000000000002394 208.0
TLS3_k127_178161_0 TIGRFAM phenylacetic acid degradation protein paaN K02618 - 1.2.1.91,3.3.2.12 0.0 1055.0
TLS3_k127_178161_1 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 626.0
TLS3_k127_178161_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 602.0
TLS3_k127_178161_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 551.0
TLS3_k127_178161_4 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 401.0
TLS3_k127_178161_5 Domain of unknown function (DUF4476) - - - 0.00000000000000000000000000000000009514 145.0
TLS3_k127_1788744_0 AsnC family K03719,K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
TLS3_k127_1788744_1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000008497 168.0
TLS3_k127_1795221_0 FAD dependent oxidoreductase K15736 - - 1.057e-205 646.0
TLS3_k127_1795221_1 Peptide-N-glycosidase F, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 374.0
TLS3_k127_1795221_2 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 347.0
TLS3_k127_1795221_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 313.0
TLS3_k127_1795221_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 294.0
TLS3_k127_1862679_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1119.0
TLS3_k127_1862679_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.118e-227 709.0
TLS3_k127_1862679_2 Fumarylacetoacetate (FAA) hydrolase family K01555 - 3.7.1.2 1.17e-198 627.0
TLS3_k127_1862679_3 OstA-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 454.0
TLS3_k127_1862679_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 342.0
TLS3_k127_1862679_5 metallopeptidase activity K01337 - 3.4.21.50 0.000000000005393 76.0
TLS3_k127_1867316_0 Nicotinate-nucleotide adenylyltransferase - - - 2.097e-240 749.0
TLS3_k127_1867316_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 542.0
TLS3_k127_1867316_10 phosphoserine phosphatase activity K02490,K07315,K20971 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000244 196.0
TLS3_k127_1867316_11 - - - - 0.000000000000000000000000000000000000000002315 165.0
TLS3_k127_1867316_12 helix_turn_helix, Lux Regulon - - - 0.0000000000000007321 87.0
TLS3_k127_1867316_2 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 515.0
TLS3_k127_1867316_3 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 380.0
TLS3_k127_1867316_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
TLS3_k127_1867316_5 UvrD/REP helicase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 327.0
TLS3_k127_1867316_6 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 304.0
TLS3_k127_1867316_7 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002718 244.0
TLS3_k127_1867316_8 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000008332 219.0
TLS3_k127_1867316_9 - - - - 0.0000000000000000000000000000000000000000000000000000006405 202.0
TLS3_k127_18691_0 histidine kinase-, DNA gyrase B - - - 8.622e-249 795.0
TLS3_k127_18691_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 602.0
TLS3_k127_18691_10 Histidine kinase - - - 0.00000000000000000000000000000000009489 149.0
TLS3_k127_18691_11 - - - - 0.00000000000000000000000000000003799 127.0
TLS3_k127_18691_12 helix_turn_helix, Lux Regulon K02479,K07692 - - 0.0000000000000000000000008071 110.0
TLS3_k127_18691_13 Short C-terminal domain - - - 0.000000000000000000000005576 102.0
TLS3_k127_18691_14 - - - - 0.00000000000000626 81.0
TLS3_k127_18691_15 membrane protein (DUF2078) K08982 - - 0.00000000003725 65.0
TLS3_k127_18691_16 response regulator, receiver K02479 - - 0.000000001412 61.0
TLS3_k127_18691_17 - - - - 0.00000001224 61.0
TLS3_k127_18691_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 452.0
TLS3_k127_18691_3 OmpA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 445.0
TLS3_k127_18691_4 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 272.0
TLS3_k127_18691_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001699 231.0
TLS3_k127_18691_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
TLS3_k127_18691_7 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000181 201.0
TLS3_k127_18691_8 - - - - 0.000000000000000000000000000000000000000000000001013 176.0
TLS3_k127_18691_9 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000002366 146.0
TLS3_k127_1876179_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1543.0
TLS3_k127_1876179_1 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000006542 147.0
TLS3_k127_1905598_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 301.0
TLS3_k127_1905598_1 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000754 219.0
TLS3_k127_1905598_2 - - - - 0.000000000000000000000005772 109.0
TLS3_k127_1905598_3 HAD family hydrolase - - - 0.00000000000000001078 89.0
TLS3_k127_1905598_4 Chain length determinant protein - - - 0.000000000000009294 85.0
TLS3_k127_1936884_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 352.0
TLS3_k127_1936884_1 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007951 283.0
TLS3_k127_1936884_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
TLS3_k127_1936884_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
TLS3_k127_1936884_4 Bacterial toxin 23 - - - 0.000000000000000000000000000000000000000000000000000000000001137 222.0
TLS3_k127_1936884_5 PFAM Kelch motif - - - 0.000000000000000000001474 106.0
TLS3_k127_1953683_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000001977 147.0
TLS3_k127_1953683_1 helix_turn_helix, Lux Regulon - - - 0.000003222 49.0
TLS3_k127_1987183_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
TLS3_k127_1987183_1 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
TLS3_k127_1987183_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
TLS3_k127_1987183_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003113 257.0
TLS3_k127_1987183_4 - - - - 0.0000000000000000000008254 95.0
TLS3_k127_1987183_5 Psort location Cytoplasmic, score 8.96 K00796 - 2.5.1.15 0.00000002535 55.0
TLS3_k127_1987183_6 Belongs to the peptidase S8 family K07004,K20755 - 3.4.21.121 0.0002042 49.0
TLS3_k127_201582_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 283.0
TLS3_k127_201582_2 Reeler domain - - - 0.00000000000000000000000000000000000000000004614 171.0
TLS3_k127_201582_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000001265 156.0
TLS3_k127_201582_4 Cytochrome c - - - 0.000000000000003705 79.0
TLS3_k127_20206_0 Alpha-2-Macroglobulin K06894 - - 0.0 1787.0
TLS3_k127_20206_1 Sodium/hydrogen exchanger family - - - 0.0 1176.0
TLS3_k127_20206_2 - - - - 0.0000000000000000000000000000000000000000000000000002302 186.0
TLS3_k127_20206_3 Belongs to the UPF0312 family - - - 0.0005033 50.0
TLS3_k127_2034939_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001233 240.0
TLS3_k127_2034939_1 Vitamin K-dependent gamma-carboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000001872 237.0
TLS3_k127_2034939_2 Belongs to the peptidase S8 family - - - 0.000000000000000008804 96.0
TLS3_k127_2035883_0 Patatin-like phospholipase K07001 - - 1.418e-245 781.0
TLS3_k127_2035883_1 beta-lactamase - - - 5.202e-205 649.0
TLS3_k127_2035883_10 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00002083 47.0
TLS3_k127_2035883_2 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 553.0
TLS3_k127_2035883_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 557.0
TLS3_k127_2035883_4 THUMP K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 477.0
TLS3_k127_2035883_5 Esterase K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 330.0
TLS3_k127_2035883_6 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006971 261.0
TLS3_k127_2035883_7 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000004323 181.0
TLS3_k127_2035883_8 Thioesterase K07107 - - 0.00000000000000000000000000000000004762 138.0
TLS3_k127_2035883_9 - - - - 0.000000000000006216 79.0
TLS3_k127_2047128_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 452.0
TLS3_k127_2047128_1 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 307.0
TLS3_k127_2047128_2 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002402 289.0
TLS3_k127_2047128_3 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000003865 205.0
TLS3_k127_2047128_4 PFAM Rhodanese-like domain - - - 0.0000000000000000000000005871 106.0
TLS3_k127_2047128_5 lipolytic protein G-D-S-L family - - - 0.0001615 51.0
TLS3_k127_2077381_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 478.0
TLS3_k127_2077381_1 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 355.0
TLS3_k127_2077381_10 Tetratricopeptide repeat - - - 0.00000000826 68.0
TLS3_k127_2077381_11 PFAM SMP-30 Gluconolaconase - - - 0.000006921 59.0
TLS3_k127_2077381_2 peptidase M1 K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 305.0
TLS3_k127_2077381_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003711 273.0
TLS3_k127_2077381_4 sodium ion export across plasma membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000007922 248.0
TLS3_k127_2077381_5 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000312 127.0
TLS3_k127_2077381_6 - - - - 0.00000000000000000000000007346 113.0
TLS3_k127_2077381_7 Peptidase family M28 - - - 0.000000000000000000006967 107.0
TLS3_k127_2077381_8 4-amino-4-deoxy-L-arabinose transferase activity K07264 - 2.4.2.43 0.00000000000000008443 91.0
TLS3_k127_2077381_9 - - - - 0.0000000000000009758 81.0
TLS3_k127_2092958_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123,K18332 - 1.12.1.3,1.17.1.9 0.0 1380.0
TLS3_k127_2092958_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 540.0
TLS3_k127_2092958_10 Domain of unknown function (DUF4286) - - - 0.00000000000000000000000000000005821 127.0
TLS3_k127_2092958_12 Lysozyme inhibitor LprI - - - 0.0000000000000001472 91.0
TLS3_k127_2092958_13 - - - - 0.00000008084 56.0
TLS3_k127_2092958_2 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 506.0
TLS3_k127_2092958_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 455.0
TLS3_k127_2092958_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 427.0
TLS3_k127_2092958_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 346.0
TLS3_k127_2092958_6 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
TLS3_k127_2092958_7 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003939 246.0
TLS3_k127_2092958_8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000001592 221.0
TLS3_k127_2092958_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002145 185.0
TLS3_k127_2093818_0 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 443.0
TLS3_k127_2093818_1 PFAM Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 367.0
TLS3_k127_2093818_10 membrane - - - 0.000000000000007241 79.0
TLS3_k127_2093818_11 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.00000000000005177 87.0
TLS3_k127_2093818_12 - - - - 0.000000001761 67.0
TLS3_k127_2093818_13 NlpC p60 family - - - 0.00000004653 64.0
TLS3_k127_2093818_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
TLS3_k127_2093818_3 Gliding motility-associated C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 323.0
TLS3_k127_2093818_4 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000003507 197.0
TLS3_k127_2093818_5 - - - - 0.0000000000000000000000000000000000000000000000000005762 197.0
TLS3_k127_2093818_6 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000004376 168.0
TLS3_k127_2093818_7 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000131 147.0
TLS3_k127_2093818_8 Conserved repeat domain - - - 0.000000000000000000000000000001615 136.0
TLS3_k127_2093818_9 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.0000000000000001442 93.0
TLS3_k127_2105333_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 510.0
TLS3_k127_2105333_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 371.0
TLS3_k127_2105333_2 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 324.0
TLS3_k127_2105333_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006892 241.0
TLS3_k127_2105333_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000001598 145.0
TLS3_k127_2105333_5 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000008285 130.0
TLS3_k127_2105333_6 Transcription elongation factor - - - 0.00000000000000000000008167 103.0
TLS3_k127_2128450_0 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 560.0
TLS3_k127_2128450_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 342.0
TLS3_k127_2128450_2 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
TLS3_k127_2128450_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001525 287.0
TLS3_k127_2128450_4 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005584 253.0
TLS3_k127_2128450_5 glyoxalase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000002343 247.0
TLS3_k127_2128450_6 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
TLS3_k127_2131739_0 COG4206 Outer membrane cobalamin receptor protein K02014 - - 2.467e-232 732.0
TLS3_k127_2131739_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 2.035e-202 647.0
TLS3_k127_2131739_2 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 327.0
TLS3_k127_2131739_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000034 192.0
TLS3_k127_2131739_4 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000004543 126.0
TLS3_k127_2131739_5 Protein of unknown function (DUF523) - - - 0.000000000000000000008929 101.0
TLS3_k127_2137815_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.768e-227 707.0
TLS3_k127_2137815_1 Collagen triple helix repeat (20 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 302.0
TLS3_k127_2137815_2 Protein of unknown function (DUF4199) - - - 0.00000000000001262 81.0
TLS3_k127_2137815_3 self proteolysis - - - 0.00000001007 62.0
TLS3_k127_2180697_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 394.0
TLS3_k127_2180697_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 350.0
TLS3_k127_2180697_2 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 320.0
TLS3_k127_2180697_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 319.0
TLS3_k127_2180697_4 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000002083 213.0
TLS3_k127_2180697_5 undecaprenyl-phosphate glucose phosphotransferase activity K19428 - - 0.000000000000000000000000000000001566 135.0
TLS3_k127_2180697_6 Belongs to the ompA family K03286 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000005448 104.0
TLS3_k127_2180697_7 Beta-lactamase enzyme family - - - 0.000000000000005584 83.0
TLS3_k127_2182628_0 Transposase domain (DUF772) K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 402.0
TLS3_k127_2182628_1 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 366.0
TLS3_k127_2202840_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0 1522.0
TLS3_k127_2202840_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.065e-290 897.0
TLS3_k127_2202840_10 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003562 240.0
TLS3_k127_2202840_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000001543 232.0
TLS3_k127_2202840_12 KTSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000002418 217.0
TLS3_k127_2202840_13 Uncharacterized protein family UPF0029 - - - 0.00000000000000000000000000000000000000000000000000005038 193.0
TLS3_k127_2202840_14 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000005083 192.0
TLS3_k127_2202840_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000001552 183.0
TLS3_k127_2202840_16 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000006518 178.0
TLS3_k127_2202840_17 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000007371 163.0
TLS3_k127_2202840_18 - - - - 0.0000000000000000000000002005 109.0
TLS3_k127_2202840_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.223e-243 762.0
TLS3_k127_2202840_20 Domain of unknown function DUF11 - - - 0.000000000000005704 75.0
TLS3_k127_2202840_22 PFAM Tetratricopeptide repeat - - - 0.0000001649 61.0
TLS3_k127_2202840_24 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0008608 51.0
TLS3_k127_2202840_3 PFAM Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 446.0
TLS3_k127_2202840_4 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 434.0
TLS3_k127_2202840_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 431.0
TLS3_k127_2202840_6 PFAM Major Facilitator Superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 406.0
TLS3_k127_2202840_7 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 398.0
TLS3_k127_2202840_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 352.0
TLS3_k127_2202840_9 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 329.0
TLS3_k127_2203782_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 580.0
TLS3_k127_2203782_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 529.0
TLS3_k127_2203782_10 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000003478 190.0
TLS3_k127_2203782_11 - - - - 0.000000000000000000000000000000000000000000000000003833 185.0
TLS3_k127_2203782_13 4-alpha-L-fucosyltransferase glycosyl transferase group 56 - - - 0.0000000000000000000000004693 119.0
TLS3_k127_2203782_14 Glycosyltransferase like family 2 - - - 0.00000000000000000000000338 114.0
TLS3_k127_2203782_15 - - - - 0.00000000000000006197 85.0
TLS3_k127_2203782_2 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 482.0
TLS3_k127_2203782_3 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 467.0
TLS3_k127_2203782_4 PFAM Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 379.0
TLS3_k127_2203782_5 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 342.0
TLS3_k127_2203782_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 316.0
TLS3_k127_2203782_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007938 281.0
TLS3_k127_2203782_8 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 269.0
TLS3_k127_2203782_9 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
TLS3_k127_2204696_0 Amidohydrolase family - - - 5.806e-293 932.0
TLS3_k127_2204696_1 PFAM Peptidase family M20 M25 M40 - - - 4.227e-238 742.0
TLS3_k127_2204696_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 356.0
TLS3_k127_2204696_11 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 336.0
TLS3_k127_2204696_12 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 306.0
TLS3_k127_2204696_13 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 281.0
TLS3_k127_2204696_14 - - - - 0.000000000000000000000000000000000000000000000000000000003386 206.0
TLS3_k127_2204696_15 - - - - 0.000000000000000000000000000000000000000000000000000007899 192.0
TLS3_k127_2204696_16 - - - - 0.000000000000000000000000000000000000000000002392 168.0
TLS3_k127_2204696_17 - - - - 0.00000000000000000000000000000001541 138.0
TLS3_k127_2204696_18 NifU-like domain - - - 0.000000000000000000000009178 102.0
TLS3_k127_2204696_19 - - - - 0.0000000259 65.0
TLS3_k127_2204696_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.432e-194 613.0
TLS3_k127_2204696_20 Cytochrome c K00406,K08906 - - 0.000004384 53.0
TLS3_k127_2204696_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K01929 - 5.1.1.1,6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 626.0
TLS3_k127_2204696_4 metallopeptidase activity K01337 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 614.0
TLS3_k127_2204696_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 581.0
TLS3_k127_2204696_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 475.0
TLS3_k127_2204696_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 458.0
TLS3_k127_2204696_8 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 430.0
TLS3_k127_2204696_9 PFAM Bacterial phospho-glucose isomerase C-terminal region K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 374.0
TLS3_k127_2221974_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 441.0
TLS3_k127_2221974_1 Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
TLS3_k127_2221974_2 membrane - - - 0.00000000000000000000000000000000000000000000004543 176.0
TLS3_k127_2226199_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 3.985e-199 624.0
TLS3_k127_2226199_1 Trypsin-like peptidase domain K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 528.0
TLS3_k127_2226199_10 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
TLS3_k127_2226199_11 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000000000001092 199.0
TLS3_k127_2226199_12 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor - - - 0.0000000000000000000000000000000000000004851 164.0
TLS3_k127_2226199_13 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000000000000000000000000000000000000008392 148.0
TLS3_k127_2226199_14 Protein of unknown function (DUF3098) - - - 0.0000000000000001148 83.0
TLS3_k127_2226199_2 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 502.0
TLS3_k127_2226199_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 370.0
TLS3_k127_2226199_4 FtsX-like permease family K09811 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 359.0
TLS3_k127_2226199_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 353.0
TLS3_k127_2226199_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 318.0
TLS3_k127_2226199_7 phosphoserine phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 314.0
TLS3_k127_2226199_8 PFAM Cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 316.0
TLS3_k127_2226199_9 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002494 253.0
TLS3_k127_2234575_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 378.0
TLS3_k127_2234575_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009811 254.0
TLS3_k127_2234575_2 S4 domain K14761 - - 0.0000000000000000003889 88.0
TLS3_k127_22539_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 557.0
TLS3_k127_22539_1 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001258 255.0
TLS3_k127_22539_2 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000297 243.0
TLS3_k127_22539_3 LysM domain - - - 0.00000000000000000000000000000000000000000000000000003349 192.0
TLS3_k127_22539_4 - - - - 0.000002205 50.0
TLS3_k127_2265140_0 PFAM Zinc-binding dehydrogenase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 492.0
TLS3_k127_2265140_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 387.0
TLS3_k127_2265140_2 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 317.0
TLS3_k127_2265140_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000179 248.0
TLS3_k127_2265140_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000466 203.0
TLS3_k127_2265140_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000006859 118.0
TLS3_k127_2271334_0 Glycosyl hydrolases family 2, sugar binding domain K01192 - 3.2.1.25 1.427e-273 864.0
TLS3_k127_2271334_1 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 1.633e-238 758.0
TLS3_k127_2271334_2 Asparaginase K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 434.0
TLS3_k127_2271334_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 419.0
TLS3_k127_2271334_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
TLS3_k127_2271334_5 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000006886 101.0
TLS3_k127_2286399_0 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 566.0
TLS3_k127_2286399_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 506.0
TLS3_k127_2286399_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000002476 177.0
TLS3_k127_2286399_3 - - - - 0.0000000007156 62.0
TLS3_k127_2291340_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1072.0
TLS3_k127_2291340_1 Hsp90 protein K04079 - - 2.879e-315 974.0
TLS3_k127_2291340_10 PFAM Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000001666 168.0
TLS3_k127_2291340_11 NUDIX domain - - - 0.0000000000000000000000000000000000001627 149.0
TLS3_k127_2291340_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000009584 138.0
TLS3_k127_2291340_13 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000005669 128.0
TLS3_k127_2291340_14 - - - - 0.0000000000000000000000000002256 121.0
TLS3_k127_2291340_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 476.0
TLS3_k127_2291340_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
TLS3_k127_2291340_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762,K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
TLS3_k127_2291340_5 Methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 304.0
TLS3_k127_2291340_6 Tellurite resistance protein TerB K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 289.0
TLS3_k127_2291340_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 294.0
TLS3_k127_2291340_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
TLS3_k127_2291340_9 PFAM Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000002917 182.0
TLS3_k127_2300331_0 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 429.0
TLS3_k127_2300331_2 ABC-2 type transporter - - - 0.000000000000000000000000001275 119.0
TLS3_k127_2300331_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000173 114.0
TLS3_k127_2306687_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1452.0
TLS3_k127_2306687_1 Participates in both transcription termination and antitermination K02600 - - 4.867e-236 733.0
TLS3_k127_2306687_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 544.0
TLS3_k127_2306687_3 tRNA hydroxylase K06169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 317.0
TLS3_k127_2306687_4 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 309.0
TLS3_k127_2306687_5 Protein of unknown function (DUF3109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000118 284.0
TLS3_k127_2306687_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001995 266.0
TLS3_k127_2306687_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000004797 171.0
TLS3_k127_2306687_8 protein conserved in bacteria - - - 0.00000000000000000000000000000001071 128.0
TLS3_k127_2306687_9 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000006389 128.0
TLS3_k127_2312218_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08314 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 363.0
TLS3_k127_2312218_1 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000004913 176.0
TLS3_k127_2312218_2 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000008827 169.0
TLS3_k127_2312218_3 Subtilase family - - - 0.00000000000000000000000000000000000003101 146.0
TLS3_k127_2312218_4 WG containing repeat - - - 0.000000000000000000000000000000000002367 143.0
TLS3_k127_2316636_0 FAD dependent oxidoreductase K00382 - 1.8.1.4 2.286e-240 750.0
TLS3_k127_2316636_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 438.0
TLS3_k127_2316636_2 SPTR CHU large protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003355 238.0
TLS3_k127_2316636_3 - - - - 0.000000000000000000000000000000000000000000000000001088 201.0
TLS3_k127_2316636_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000002718 189.0
TLS3_k127_2316636_6 - - - - 0.00000000000000000000000001596 109.0
TLS3_k127_2317160_0 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.00000000000000000000000006155 119.0
TLS3_k127_2317160_1 - - - - 0.000000000002467 70.0
TLS3_k127_2317160_2 - - - - 0.00000001031 68.0
TLS3_k127_2317160_3 - - - - 0.0000323 54.0
TLS3_k127_2317427_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003819 272.0
TLS3_k127_2317427_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
TLS3_k127_2317427_2 Damage-inducible protein DinB - - - 0.000000000000000000000000000000000000000000000000000000007026 202.0
TLS3_k127_2317427_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000001822 171.0
TLS3_k127_2317427_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000001949 134.0
TLS3_k127_2317427_6 - - - - 0.0000000000008401 73.0
TLS3_k127_2322518_0 AAA ATPase central domain protein - - - 0.00000000000000000000004995 108.0
TLS3_k127_2322518_1 peptidase - - - 0.000004281 61.0
TLS3_k127_2337718_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102,K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 491.0
TLS3_k127_2337718_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 480.0
TLS3_k127_2337718_2 Rho termination factor, N-terminal domain - - - 0.0006313 48.0
TLS3_k127_2359544_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.584e-292 900.0
TLS3_k127_2359544_1 Calx-beta domain - - - 7.535e-284 894.0
TLS3_k127_2359544_10 PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000002963 123.0
TLS3_k127_2359544_11 Fibronectin type III domain K20276 - - 0.000000000003525 79.0
TLS3_k127_2359544_2 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 7.632e-252 789.0
TLS3_k127_2359544_3 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 2.215e-220 700.0
TLS3_k127_2359544_4 ABC-type transport system involved in lipoprotein release permease component K09808,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 398.0
TLS3_k127_2359544_5 Pkd domain containing protein K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 363.0
TLS3_k127_2359544_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 346.0
TLS3_k127_2359544_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 335.0
TLS3_k127_2359544_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000005868 157.0
TLS3_k127_2359544_9 Peptidase family M23 - - - 0.000000000000000000000000000000000000000009389 165.0
TLS3_k127_23723_0 Uncharacterized protein family (UPF0051) K09014 - - 2.855e-284 876.0
TLS3_k127_23723_1 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 430.0
TLS3_k127_23723_10 - - - - 0.0000002819 55.0
TLS3_k127_23723_11 iron ion homeostasis K02012 - - 0.00006274 54.0
TLS3_k127_23723_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 399.0
TLS3_k127_23723_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 298.0
TLS3_k127_23723_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
TLS3_k127_23723_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008161 250.0
TLS3_k127_23723_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000004354 193.0
TLS3_k127_23723_7 TIGRFAM Iron-sulfur cluster assembly accessory protein K13628 - - 0.00000000000000000000000000000000000000000000000000009532 187.0
TLS3_k127_23723_8 - - - - 0.000000000000000000000000000000000002037 147.0
TLS3_k127_23723_9 phosphohistidine phosphatase K08296 - - 0.0000001925 59.0
TLS3_k127_2378521_0 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 1.447e-217 717.0
TLS3_k127_2378521_1 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 325.0
TLS3_k127_2378521_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
TLS3_k127_2378521_3 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 268.0
TLS3_k127_2378521_4 PFAM PKD domain - - - 0.000000000000000000000000003478 127.0
TLS3_k127_2378521_6 - - - - 0.000000000000000004747 91.0
TLS3_k127_2378521_7 Belongs to the peptidase S8 family - - - 0.0000000000000002345 93.0
TLS3_k127_2392058_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 387.0
TLS3_k127_2392058_1 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000000000000000000000000000000000000007468 191.0
TLS3_k127_2392058_2 - - - - 0.000000000000000000000000000000000000000007554 168.0
TLS3_k127_2392058_3 - - - - 0.0007567 47.0
TLS3_k127_2393394_0 PFAM Mur ligase family, catalytic domain K01924,K02558 - 6.3.2.45,6.3.2.8 4.925e-221 692.0
TLS3_k127_2393394_1 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 285.0
TLS3_k127_2393394_2 ApbE family K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000515 270.0
TLS3_k127_239413_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.805e-200 633.0
TLS3_k127_2402484_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 4.693e-214 689.0
TLS3_k127_2402484_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 548.0
TLS3_k127_2402484_10 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000001895 78.0
TLS3_k127_2402484_11 - - - - 0.00005615 53.0
TLS3_k127_2402484_2 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 491.0
TLS3_k127_2402484_3 Phenylacetate-CoA oxygenase K02609 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 462.0
TLS3_k127_2402484_4 PFAM Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 310.0
TLS3_k127_2402484_5 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000006474 235.0
TLS3_k127_2402484_6 CRP FNR family transcriptional regulator K01420 - - 0.000000000000000000000000000000000000000000000000000000001578 207.0
TLS3_k127_2402484_7 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000000000008161 174.0
TLS3_k127_2402484_8 Phenylacetic acid degradation B K02610 - - 0.0000000000000000000000000000000006004 132.0
TLS3_k127_2402484_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000007812 94.0
TLS3_k127_2416666_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000006611 164.0
TLS3_k127_2416666_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000000004213 158.0
TLS3_k127_2429811_0 OmpA family K03640 - - 3.96e-265 833.0
TLS3_k127_2429811_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 6.696e-218 679.0
TLS3_k127_2429811_10 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000000000000000002714 175.0
TLS3_k127_2429811_11 positive regulation of macromolecule biosynthetic process K03973 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944 - 0.0000000000000000000000000000005738 123.0
TLS3_k127_2429811_12 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.000000000000000218 90.0
TLS3_k127_2429811_13 Belongs to the LOG family K06966 - 3.2.2.10 0.000009607 47.0
TLS3_k127_2429811_2 alanine symporter K03310 - - 4.143e-205 653.0
TLS3_k127_2429811_3 - - - - 3.142e-199 644.0
TLS3_k127_2429811_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 520.0
TLS3_k127_2429811_5 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 366.0
TLS3_k127_2429811_6 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 328.0
TLS3_k127_2429811_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000005412 263.0
TLS3_k127_2429811_8 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004599 254.0
TLS3_k127_2429811_9 PASTA K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
TLS3_k127_2455161_0 PFAM Cys Met metabolism PLP-dependent enzyme - - - 1.682e-290 902.0
TLS3_k127_2455161_1 Cation transport protein K03498 - - 2.964e-258 804.0
TLS3_k127_2455161_10 Two component regulator propeller - - - 0.000000000000000000009335 94.0
TLS3_k127_2455161_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 432.0
TLS3_k127_2455161_3 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 377.0
TLS3_k127_2455161_4 - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 310.0
TLS3_k127_2455161_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
TLS3_k127_2455161_6 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003893 253.0
TLS3_k127_2455161_7 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000011 250.0
TLS3_k127_2455161_8 XRE family transcriptional regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
TLS3_k127_2455161_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000002173 136.0
TLS3_k127_2464176_0 ATPase activity K16907 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 391.0
TLS3_k127_2464176_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001346 222.0
TLS3_k127_2464176_2 - K16905 - - 0.0000000000000000000000000000000000000000000000000007228 192.0
TLS3_k127_2464176_3 transmembrane transport K16906 - - 0.0000000000000000000000000000000000000000000004442 175.0
TLS3_k127_2472363_0 C-terminal domain of CHU protein family - - - 0.0 1322.0
TLS3_k127_2472363_1 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
TLS3_k127_2472363_2 Pkd domain containing protein K01337 - 3.4.21.50 0.00000000000000000000000000000005821 127.0
TLS3_k127_2533237_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 389.0
TLS3_k127_2533237_1 8-amino-7-oxononanoate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 277.0
TLS3_k127_2533237_2 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000000001399 178.0
TLS3_k127_254248_0 C-terminal domain of CHU protein family - - - 0.0 1401.0
TLS3_k127_254248_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1317.0
TLS3_k127_254248_10 Dolichyl-phosphate-mannose-protein mannosyltransferase K07264 - 2.4.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 400.0
TLS3_k127_254248_11 phosphate ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 313.0
TLS3_k127_254248_12 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000308 188.0
TLS3_k127_254248_13 addiction module antidote protein HigA - - - 0.000000000000000000000000000006971 122.0
TLS3_k127_254248_14 addiction module antidote protein HigA - - - 0.00000000000000000000000000002258 120.0
TLS3_k127_254248_15 - - - - 0.0000000000000000000001068 107.0
TLS3_k127_254248_16 Belongs to the peptidase S8 family K13276 - - 0.000189 51.0
TLS3_k127_254248_2 C-terminal domain of CHU protein family K01337 - 3.4.21.50 0.0 1246.0
TLS3_k127_254248_3 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 5.184e-301 930.0
TLS3_k127_254248_4 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.817e-272 845.0
TLS3_k127_254248_5 OmpA family - - - 5.402e-228 727.0
TLS3_k127_254248_6 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.918e-221 696.0
TLS3_k127_254248_7 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 515.0
TLS3_k127_254248_8 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 501.0
TLS3_k127_254248_9 TonB-dependent receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 443.0
TLS3_k127_2565033_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1277.0
TLS3_k127_2565033_1 ATPase family associated with various cellular activities (AAA) K03696 - - 0.0 1241.0
TLS3_k127_2565033_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000008399 143.0
TLS3_k127_2586342_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 493.0
TLS3_k127_2586342_1 Cytochrome c - - - 0.00000948 50.0
TLS3_k127_262564_0 PFAM tRNA synthetases class I (I, L, M and V) K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1450.0
TLS3_k127_262564_1 Carboxypeptidase regulatory-like domain - - - 0.0 1054.0
TLS3_k127_262564_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 311.0
TLS3_k127_262564_11 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 304.0
TLS3_k127_262564_12 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003625 272.0
TLS3_k127_262564_13 PFAM MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004214 261.0
TLS3_k127_262564_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001949 256.0
TLS3_k127_262564_15 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000004645 218.0
TLS3_k127_262564_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000003883 223.0
TLS3_k127_262564_17 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K20866 - 3.1.3.10 0.00000000000000000000000000000000000000000000000000001263 195.0
TLS3_k127_262564_18 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000007364 180.0
TLS3_k127_262564_19 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000002105 174.0
TLS3_k127_262564_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.687e-232 724.0
TLS3_k127_262564_20 - - - - 0.00000000000000000000000000000000000000000001331 165.0
TLS3_k127_262564_21 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000001748 141.0
TLS3_k127_262564_22 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000002474 104.0
TLS3_k127_262564_23 Zinc metalloprotease (Elastase) - - - 0.0000000000000001258 95.0
TLS3_k127_262564_24 SPTR CHU large protein - - - 0.0000000000000001659 94.0
TLS3_k127_262564_25 YceI-like domain - - - 0.000000000000003241 85.0
TLS3_k127_262564_26 PD-(D/E)XK nuclease superfamily - - - 0.000000000000385 76.0
TLS3_k127_262564_3 MORN repeat variant - - - 5.335e-217 687.0
TLS3_k127_262564_4 PFAM Signal transduction histidine kinase, internal region - - - 1.791e-213 685.0
TLS3_k127_262564_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.986e-197 631.0
TLS3_k127_262564_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 400.0
TLS3_k127_262564_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 392.0
TLS3_k127_262564_8 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 384.0
TLS3_k127_262564_9 PFAM Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 371.0
TLS3_k127_269221_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1456.0
TLS3_k127_269221_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 4.833e-209 655.0
TLS3_k127_269221_2 Cys/Met metabolism PLP-dependent enzyme K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 483.0
TLS3_k127_269221_3 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000000000000001813 214.0
TLS3_k127_269221_4 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000001537 177.0
TLS3_k127_269221_5 TIGRFAM FeS assembly SUF system protein - - - 0.00000000000000000000000000000000000000000002639 162.0
TLS3_k127_269221_6 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000004491 148.0
TLS3_k127_2706024_0 Rhs element Vgr protein - - - 5.868e-245 764.0
TLS3_k127_2706024_1 LysM domain - - - 0.000000000000000000000000003612 111.0
TLS3_k127_2718130_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 2.242e-194 611.0
TLS3_k127_2718130_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 631.0
TLS3_k127_2718130_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 552.0
TLS3_k127_2718130_3 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 373.0
TLS3_k127_2718130_4 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
TLS3_k127_2756396_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 0.0 1174.0
TLS3_k127_2756396_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 485.0
TLS3_k127_2756396_2 Succinate dehydrogenase fumarate reductase Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 452.0
TLS3_k127_2756396_3 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
TLS3_k127_2756396_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008719 284.0
TLS3_k127_2756396_5 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000841 266.0
TLS3_k127_2756396_6 - - - - 0.0006157 48.0
TLS3_k127_275819_0 Motility related/secretion protein - - - 0.0 3144.0
TLS3_k127_275819_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0 1218.0
TLS3_k127_275819_2 COGs COG2823 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 284.0
TLS3_k127_275819_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 282.0
TLS3_k127_275819_4 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000007191 224.0
TLS3_k127_275819_5 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000001274 175.0
TLS3_k127_275819_6 Transcriptional regulator K02529 - - 0.00002678 49.0
TLS3_k127_2776671_0 PFAM Alanine dehydrogenase PNT, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 550.0
TLS3_k127_2776671_1 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270,K21749 - 2.7.7.43,2.7.7.92,3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
TLS3_k127_2776671_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000001213 240.0
TLS3_k127_2781719_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 488.0
TLS3_k127_2781719_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 313.0
TLS3_k127_2781719_2 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
TLS3_k127_2781719_3 Beta-lactamase K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000006605 207.0
TLS3_k127_2781719_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000002829 193.0
TLS3_k127_2781719_5 Histidine kinase - - - 0.000000000000000000000000000003587 125.0
TLS3_k127_2781719_6 endo-1,4-beta-xylanase activity K01179,K07407 - 3.2.1.22,3.2.1.4 0.00002213 57.0
TLS3_k127_278929_0 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 600.0
TLS3_k127_278929_1 leucine- rich repeat protein - - - 0.0000000000000000000000000000000000003776 156.0
TLS3_k127_278929_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000002776 134.0
TLS3_k127_278929_3 cellulose binding - - - 0.00009243 46.0
TLS3_k127_278929_4 Pectate lyase - - - 0.0008608 51.0
TLS3_k127_280884_0 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000002497 140.0
TLS3_k127_280884_1 Antibiotic biosynthesis monooxygenase - - - 0.0001392 51.0
TLS3_k127_2818646_0 - - - - 0.00000000000000000000000000000002249 129.0
TLS3_k127_2818646_3 - - - - 0.0000000000000002947 85.0
TLS3_k127_2818646_4 Catalase - - - 0.0000000002913 61.0
TLS3_k127_2818646_5 - - - - 0.000000002025 60.0
TLS3_k127_2844301_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.529e-231 721.0
TLS3_k127_2844301_1 B12 binding domain K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 553.0
TLS3_k127_2844301_10 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
TLS3_k127_2844301_11 - - - - 0.0000000000000000000000000000000000000000000000001544 179.0
TLS3_k127_2844301_12 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000004415 182.0
TLS3_k127_2844301_13 - - - - 0.000000000000000000000000000000000001257 148.0
TLS3_k127_2844301_14 Tellurite resistance protein TerB - - - 0.000000000000000000000000000002609 124.0
TLS3_k127_2844301_15 cell cycle K05589,K12065,K13052 - - 0.000000000000000002792 87.0
TLS3_k127_2844301_17 antisigma factor binding K04749,K06378 - - 0.00000001402 61.0
TLS3_k127_2844301_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 437.0
TLS3_k127_2844301_3 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 361.0
TLS3_k127_2844301_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 351.0
TLS3_k127_2844301_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 329.0
TLS3_k127_2844301_6 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 311.0
TLS3_k127_2844301_7 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002427 273.0
TLS3_k127_2844301_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
TLS3_k127_2844301_9 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
TLS3_k127_2860479_0 phage tail tape measure protein - - - 1.122e-243 778.0
TLS3_k127_2868298_0 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 465.0
TLS3_k127_2868298_1 AAA domain, putative AbiEii toxin, Type IV TA system K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 318.0
TLS3_k127_2872464_0 PFAM Metallo-beta-lactamase superfamily - - - 2.223e-210 662.0
TLS3_k127_2872464_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 527.0
TLS3_k127_2872464_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 357.0
TLS3_k127_2872464_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 336.0
TLS3_k127_2872464_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 324.0
TLS3_k127_2872464_5 Heavy-metal-associated domain - - - 0.0000001308 60.0
TLS3_k127_2894328_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 511.0
TLS3_k127_2894328_1 Protein of unknown function (DUF2490) - - - 0.0000000000000000000002155 106.0
TLS3_k127_2929655_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.036e-254 795.0
TLS3_k127_2929655_1 radical SAM domain protein - - - 1.102e-232 729.0
TLS3_k127_2929655_2 - - - - 0.000000000000000000000000000000000000000000000000000000008186 204.0
TLS3_k127_2929655_3 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0001924 49.0
TLS3_k127_2934626_0 periplasmic ligand-binding sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 299.0
TLS3_k127_2934626_1 MvaI/BcnI restriction endonuclease family - - - 0.00000000000000000000000000000000000000000000000000016 185.0
TLS3_k127_2934626_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000003027 170.0
TLS3_k127_2934626_3 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000002258 159.0
TLS3_k127_2934626_4 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000001041 174.0
TLS3_k127_2936647_0 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 476.0
TLS3_k127_2936647_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000003251 230.0
TLS3_k127_2936647_10 Cellulose synthase K20543 - - 0.00005146 53.0
TLS3_k127_2936647_11 - - - - 0.0002469 51.0
TLS3_k127_2936647_2 chelatase, subunit chli K07391 - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
TLS3_k127_2936647_3 - - - - 0.000000000000000000000000000000000000000000000000000003086 194.0
TLS3_k127_2936647_5 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000003432 183.0
TLS3_k127_2936647_7 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000001359 108.0
TLS3_k127_2936647_8 SMI1 / KNR4 family - - - 0.00000000000000000000211 100.0
TLS3_k127_29611_0 Coenzyme A transferase K01029,K01032 - 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 409.0
TLS3_k127_29611_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 332.0
TLS3_k127_29611_2 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 316.0
TLS3_k127_29611_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 299.0
TLS3_k127_29611_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001964 276.0
TLS3_k127_29611_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000008207 247.0
TLS3_k127_29611_6 Pregnancy-associated plasma protein-A - - - 0.0007961 44.0
TLS3_k127_2971399_0 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 359.0
TLS3_k127_2971399_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000007329 147.0
TLS3_k127_2971399_2 PKD domain - - - 0.00000000000003178 86.0
TLS3_k127_2971399_3 domain, Protein K06113,K12685 - 3.2.1.99 0.00000000000009746 84.0
TLS3_k127_2971399_4 Arylsulfotransferase (ASST) - - - 0.0000000000003211 83.0
TLS3_k127_2971399_5 Arylsulfotransferase (ASST) - - - 0.00005466 56.0
TLS3_k127_2978065_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005693 276.0
TLS3_k127_2978065_1 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000001658 194.0
TLS3_k127_2978065_10 pathogenesis - - - 0.0004838 53.0
TLS3_k127_2978065_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000004723 104.0
TLS3_k127_2978382_0 Salmonella virulence plasmid 28.1kDa A protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002349 284.0
TLS3_k127_3002216_0 helicase superfamily c-terminal domain - - - 5.444e-241 751.0
TLS3_k127_3002216_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000006572 143.0
TLS3_k127_3009403_0 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
TLS3_k127_3009403_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004908 245.0
TLS3_k127_3009403_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000001417 211.0
TLS3_k127_3009403_3 - - - - 0.0000000000000000000000000000000000000000000000000000003495 199.0
TLS3_k127_301505_0 TIGRFAM DNA topoisomerase III, bacteria and conjugative plasmid K03169 - 5.99.1.2 0.0 1043.0
TLS3_k127_301505_1 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 8.708e-297 935.0
TLS3_k127_301505_10 PhnA domain K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000000002856 237.0
TLS3_k127_301505_11 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000001381 241.0
TLS3_k127_301505_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000002067 227.0
TLS3_k127_301505_13 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000002392 228.0
TLS3_k127_301505_14 - - - - 0.0000000000000000000000000000000000000000000000000000009782 203.0
TLS3_k127_301505_15 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.00000000000000000000000000000000000000000004352 167.0
TLS3_k127_301505_16 - - - - 0.000000000000000000000000001665 119.0
TLS3_k127_301505_17 Domain of unknown function (DUF4440) - - - 0.0000000000000000002134 102.0
TLS3_k127_301505_18 Protein of unknown function (DUF1616) - - - 0.000000000379 63.0
TLS3_k127_301505_2 PFAM AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 5.97e-215 676.0
TLS3_k127_301505_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 576.0
TLS3_k127_301505_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 489.0
TLS3_k127_301505_5 TIGRFAM Orotidine 5'-phosphate decarboxylase, subfamily 2 K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 439.0
TLS3_k127_301505_6 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 441.0
TLS3_k127_301505_7 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 376.0
TLS3_k127_301505_8 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 328.0
TLS3_k127_301505_9 Bacterial capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 329.0
TLS3_k127_3047003_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 515.0
TLS3_k127_3047003_1 Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 469.0
TLS3_k127_3047003_2 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 449.0
TLS3_k127_3047003_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000006558 229.0
TLS3_k127_3072735_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 596.0
TLS3_k127_3072735_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 437.0
TLS3_k127_3072735_2 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 315.0
TLS3_k127_3072735_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000007281 186.0
TLS3_k127_3072735_4 decarboxylase K01585 - 4.1.1.19 0.000000000000001242 76.0
TLS3_k127_3075239_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 557.0
TLS3_k127_3075239_1 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008124 279.0
TLS3_k127_3075239_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000004861 198.0
TLS3_k127_3075239_3 OsmC-like protein - - - 0.00000000000002867 76.0
TLS3_k127_3075239_4 protein serine/threonine kinase activity K13412,K14005,K19690 GO:0002831,GO:0002833,GO:0007162,GO:0008150,GO:0009272,GO:0009405,GO:0009607,GO:0009987,GO:0010033,GO:0010570,GO:0022407,GO:0022408,GO:0030100,GO:0030155,GO:0030447,GO:0032879,GO:0033993,GO:0036180,GO:0040007,GO:0040008,GO:0042221,GO:0042546,GO:0042710,GO:0043900,GO:0044010,GO:0044011,GO:0044085,GO:0044182,GO:0044419,GO:0044764,GO:0045806,GO:0045927,GO:0046677,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0050896,GO:0051040,GO:0051042,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051703,GO:0051704,GO:0051716,GO:0060627,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071554,GO:0071840,GO:0071852,GO:0090033,GO:0090605,GO:0090609,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:1900190,GO:1900231,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901700,GO:1901701 2.7.11.1,2.7.13.3 0.000000000153 74.0
TLS3_k127_3090385_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 9.924e-229 713.0
TLS3_k127_3090385_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 599.0
TLS3_k127_3090385_10 Conserved repeat domain - - - 0.0000000000000000000000000000004891 140.0
TLS3_k127_3090385_11 domain protein - - - 0.0000000000000000000000001349 123.0
TLS3_k127_3090385_12 self proteolysis K20276 - - 0.000000000000000306 93.0
TLS3_k127_3090385_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005085 72.0
TLS3_k127_3090385_14 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000001891 61.0
TLS3_k127_3090385_15 positive regulation of lateral motor column neuron migration K06249 GO:0000902,GO:0000904,GO:0001101,GO:0001764,GO:0001932,GO:0001934,GO:0001941,GO:0003002,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007417,GO:0007420,GO:0007494,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007626,GO:0008104,GO:0008150,GO:0008152,GO:0008306,GO:0008347,GO:0009410,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010001,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010243,GO:0010468,GO:0010469,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0014066,GO:0014068,GO:0014070,GO:0016043,GO:0016310,GO:0016358,GO:0016477,GO:0017085,GO:0018108,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0021510,GO:0021511,GO:0021517,GO:0021536,GO:0021537,GO:0021542,GO:0021543,GO:0021761,GO:0021766,GO:0021769,GO:0021795,GO:0021799,GO:0021800,GO:0021801,GO:0021819,GO:0021854,GO:0021885,GO:0021987,GO:0022008,GO:0022029,GO:0022030,GO:0022603,GO:0022604,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030900,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031503,GO:0031644,GO:0031646,GO:0031960,GO:0032006,GO:0032008,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032570,GO:0032793,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033036,GO:0033555,GO:0033674,GO:0033993,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035176,GO:0035295,GO:0035418,GO:0035690,GO:0036211,GO:0036477,GO:0038026,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043113,GO:0043170,GO:0043200,GO:0043204,GO:0043269,GO:0043270,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044421,GO:0044424,GO:0044463,GO:0044464,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0046677,GO:0048167,GO:0048265,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048565,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051057,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051668,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051960,GO:0051962,GO:0051966,GO:0051968,GO:0055123,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061097,GO:0061098,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070325,GO:0070326,GO:0070542,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072578,GO:0072657,GO:0080090,GO:0090128,GO:0090129,GO:0097106,GO:0097107,GO:0097114,GO:0097119,GO:0097120,GO:0097305,GO:0097327,GO:0097447,GO:0097458,GO:0097475,GO:0097476,GO:0097477,GO:0097485,GO:0098698,GO:0098815,GO:0099068,GO:0099084,GO:0099173,GO:0099175,GO:0099177,GO:0099601,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:1900006,GO:1900271,GO:1900273,GO:1900449,GO:1900451,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1902076,GO:1902078,GO:1902531,GO:1902533,GO:1903506,GO:1904062,GO:1904064,GO:1904861,GO:1905483,GO:1905485,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000311,GO:2000463,GO:2000969,GO:2001141,GO:2001222,GO:2001224,GO:2001257,GO:2001259 - 0.000000699 63.0
TLS3_k127_3090385_16 Cell surface spherulin 4-like protein - - - 0.00001126 58.0
TLS3_k127_3090385_2 PFAM Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 565.0
TLS3_k127_3090385_3 metallopeptidase activity K01337 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 556.0
TLS3_k127_3090385_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 346.0
TLS3_k127_3090385_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001803 236.0
TLS3_k127_3090385_7 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001914 232.0
TLS3_k127_3090385_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001409 202.0
TLS3_k127_3090385_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000126 141.0
TLS3_k127_3117682_0 DegT/DnrJ/EryC1/StrS aminotransferase family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 573.0
TLS3_k127_3117682_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 292.0
TLS3_k127_3117682_2 ArsR family transcriptional regulator - - - 0.00000000000006352 76.0
TLS3_k127_3133730_0 PFAM Peptidase family M13 K07386 - - 6.615e-219 691.0
TLS3_k127_3133730_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 545.0
TLS3_k127_3133730_2 Protein of unknown function (DUF3078) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 328.0
TLS3_k127_3133730_3 Flavodoxin-like fold K00355,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
TLS3_k127_3133730_4 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000003318 212.0
TLS3_k127_3133730_5 - - - - 0.000000000000000000000000003097 119.0
TLS3_k127_3139899_0 TonB dependent receptor K16087 - - 0.0 1041.0
TLS3_k127_3139899_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000004698 214.0
TLS3_k127_3139899_2 protein homooligomerization - - - 0.000000000000000000000000000000000000000001352 173.0
TLS3_k127_3139899_3 - - - - 0.000000000000000000696 93.0
TLS3_k127_3161884_0 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 495.0
TLS3_k127_3161884_1 Belongs to the proline racemase family K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002161 248.0
TLS3_k127_316262_0 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 413.0
TLS3_k127_316262_1 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 365.0
TLS3_k127_316262_2 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000002085 126.0
TLS3_k127_3195482_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1305.0
TLS3_k127_3223156_0 GHKL domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 546.0
TLS3_k127_3223156_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 421.0
TLS3_k127_3263189_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 311.0
TLS3_k127_3263189_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005543 265.0
TLS3_k127_3263189_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000004288 156.0
TLS3_k127_3263189_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000002068 142.0
TLS3_k127_3263189_4 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000001552 125.0
TLS3_k127_3268691_0 - - - - 0.0 1490.0
TLS3_k127_3268691_1 PFAM Bacterial trigger factor protein (TF) K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 591.0
TLS3_k127_3268691_11 Pkd domain containing protein - - - 0.00002759 58.0
TLS3_k127_3268691_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 454.0
TLS3_k127_3268691_3 Large extracellular alpha-helical protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 289.0
TLS3_k127_3268691_4 Domain of unknown function (DUF3127) - - - 0.000000000000000000000000000000000000000000000000000000008059 202.0
TLS3_k127_3268691_5 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000005735 197.0
TLS3_k127_3268691_6 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000005922 189.0
TLS3_k127_3268691_7 lysyltransferase activity K07027 - - 0.00000000000000000000000001135 119.0
TLS3_k127_3268691_8 C-terminal domain of CHU protein family - - - 0.00000000000000000000008613 115.0
TLS3_k127_3268691_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000006597 63.0
TLS3_k127_3272398_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 597.0
TLS3_k127_3272398_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000003224 176.0
TLS3_k127_3272398_2 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000002021 167.0
TLS3_k127_3272398_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000207 106.0
TLS3_k127_3272398_4 phosphorelay signal transduction system K13587 - 2.7.13.3 0.0000000008599 68.0
TLS3_k127_3273909_0 Peptidase dimerisation domain K01258 - 3.4.11.4 2.28e-206 649.0
TLS3_k127_3273909_1 prohibitin homologues K07192 - - 6.906e-204 644.0
TLS3_k127_3273909_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000004792 239.0
TLS3_k127_3273909_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000001165 235.0
TLS3_k127_3273909_12 Domain of unknown function (DUF4924) - - - 0.000000000000000000000000000000000000000000000000000000000000000001199 232.0
TLS3_k127_3273909_13 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007982 234.0
TLS3_k127_3273909_14 serine protease - - - 0.00000000000000000000000000000000000000000000000000037 190.0
TLS3_k127_3273909_15 Domain of unknown function (DUF1987) - - - 0.000000000000000000000000000000000000000000000001535 176.0
TLS3_k127_3273909_16 pfam nudix - - - 0.000000000000000000000000000000000000000238 156.0
TLS3_k127_3273909_17 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000002821 139.0
TLS3_k127_3273909_18 unfolded protein binding K00507,K06142,K13924 - 1.14.19.1,2.1.1.80,3.1.1.61 0.00000000000000000000000001292 117.0
TLS3_k127_3273909_19 - - - - 0.000000000000000000000003807 107.0
TLS3_k127_3273909_2 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 557.0
TLS3_k127_3273909_21 - - - - 0.000000000000000000000008089 104.0
TLS3_k127_3273909_24 spectrin binding K15502,K15503 - - 0.00004577 51.0
TLS3_k127_3273909_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 502.0
TLS3_k127_3273909_4 PFAM ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 407.0
TLS3_k127_3273909_5 PFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 372.0
TLS3_k127_3273909_6 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 365.0
TLS3_k127_3273909_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 357.0
TLS3_k127_3273909_8 Hexapeptide repeat of succinyl-transferase K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 342.0
TLS3_k127_3273909_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000003252 254.0
TLS3_k127_3275943_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 480.0
TLS3_k127_3275943_1 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000000000000000005082 155.0
TLS3_k127_3275943_2 TamB, inner membrane protein subunit of TAM complex - - - 0.00000000000000000000000000000000000000009791 161.0
TLS3_k127_3275943_3 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000002297 154.0
TLS3_k127_3275943_4 - - - - 0.0000000000000000000000000003105 117.0
TLS3_k127_3283399_0 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000007638 220.0
TLS3_k127_3283399_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000009625 198.0
TLS3_k127_3283399_2 - - - - 0.0000000000000000000000002838 117.0
TLS3_k127_3283399_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000001909 102.0
TLS3_k127_3283399_4 SprB repeat - - - 0.0000000000007423 81.0
TLS3_k127_3283399_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0007093 49.0
TLS3_k127_3288137_0 Outer membrane protein protective antigen OMA87 - - - 3.568e-224 725.0
TLS3_k127_3288137_1 SpoU rRNA Methylase family K03437 - - 0.000000000009878 69.0
TLS3_k127_3300907_0 M61 glycyl aminopeptidase - - - 1.413e-231 733.0
TLS3_k127_3300907_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 463.0
TLS3_k127_3300907_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
TLS3_k127_3300907_3 AMP-binding enzyme C-terminal domain K01897,K18660 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 332.0
TLS3_k127_3300907_4 Multidrug ABC transporter ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
TLS3_k127_3300907_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002025 245.0
TLS3_k127_3300907_6 Transposase K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
TLS3_k127_3300907_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000005569 68.0
TLS3_k127_3301072_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.938e-295 915.0
TLS3_k127_3301072_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000001783 186.0
TLS3_k127_3301072_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000039 160.0
TLS3_k127_3301072_3 C-terminal domain of CHU protein family - - - 0.0000000000004499 83.0
TLS3_k127_3303912_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1452.0
TLS3_k127_3303912_1 POT family K03305 - - 2.213e-281 878.0
TLS3_k127_3303912_2 Leukotriene A4 hydrolase, C-terminal - - - 5.855e-230 728.0
TLS3_k127_3303912_3 amino acid peptide transporter K03305 - - 1.527e-211 670.0
TLS3_k127_3303912_4 Amidohydrolase family - - - 2.072e-200 638.0
TLS3_k127_3303912_5 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 511.0
TLS3_k127_3303912_6 ABC-type multidrug transport system ATPase and permease K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 394.0
TLS3_k127_3303912_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001209 236.0
TLS3_k127_3303912_8 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000004958 184.0
TLS3_k127_3318544_0 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002325 270.0
TLS3_k127_3318544_1 self proteolysis - - - 0.0000002642 58.0
TLS3_k127_3325165_0 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 488.0
TLS3_k127_3325165_1 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 315.0
TLS3_k127_3339959_0 PFAM FG-GAP repeat - - - 8.31e-207 668.0
TLS3_k127_3339959_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002595 248.0
TLS3_k127_3339959_2 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.00000000000000000000000001275 113.0
TLS3_k127_3339959_3 - - - - 0.0000000000001436 76.0
TLS3_k127_3341724_0 Peptide-N-glycosidase F, C terminal - - - 9.751e-285 897.0
TLS3_k127_3341724_1 Peptidase M14, carboxypeptidase A - - - 0.00000001634 57.0
TLS3_k127_3371957_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
TLS3_k127_3371957_1 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000006138 214.0
TLS3_k127_3371957_2 Acetyltransferase (GNAT) domain K03828 - - 0.000000000000000000000000000000000000000000000000009813 183.0
TLS3_k127_3371957_3 - - - - 0.000000000000000006693 93.0
TLS3_k127_3387682_0 - - - - 1.488e-209 666.0
TLS3_k127_3387682_1 AhpC TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 286.0
TLS3_k127_3387682_10 metallopeptidase activity - - - 0.000000249 61.0
TLS3_k127_3387682_2 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001655 259.0
TLS3_k127_3387682_3 Outer membrane protein Omp28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001096 241.0
TLS3_k127_3387682_4 Outer membrane protein Omp28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001238 243.0
TLS3_k127_3387682_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000001872 171.0
TLS3_k127_3387682_6 Gliding motility protein RemB - - - 0.0000000000000000000000000000000000000005941 158.0
TLS3_k127_3387682_7 UbiA prenyltransferase family - - - 0.000000000000000000000000001748 123.0
TLS3_k127_3387682_8 Pkd domain containing protein - - - 0.00000000000000001453 92.0
TLS3_k127_3389319_0 Stage II sporulation protein M - - - 2.337e-198 638.0
TLS3_k127_3389319_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003276 246.0
TLS3_k127_3389319_2 - - - - 0.0000000000000000000000000000000000000000000000000001534 196.0
TLS3_k127_3389319_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000007945 139.0
TLS3_k127_3394241_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.00000000000000000001082 108.0
TLS3_k127_3401514_0 PFAM DNA gyrase topoisomerase IV, subunit A K02621 - - 0.0 1421.0
TLS3_k127_3401514_1 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02622 - - 0.0 1094.0
TLS3_k127_3401514_10 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 278.0
TLS3_k127_3401514_11 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000185 273.0
TLS3_k127_3401514_12 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003573 245.0
TLS3_k127_3401514_13 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000001534 174.0
TLS3_k127_3401514_14 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000001655 169.0
TLS3_k127_3401514_15 - - - - 0.00000000000000000000000000000000000000000002053 168.0
TLS3_k127_3401514_16 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000905 161.0
TLS3_k127_3401514_17 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.0000000000000000000000000000000000000008765 165.0
TLS3_k127_3401514_18 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000154 155.0
TLS3_k127_3401514_19 STAS domain - - - 0.0000000000000000000000000000000000001642 143.0
TLS3_k127_3401514_2 ABC transporter C-terminal domain K15738 - - 1.6e-290 902.0
TLS3_k127_3401514_20 FG-GAP repeat - - - 0.00000000000000000000000000000000003009 154.0
TLS3_k127_3401514_21 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor - - - 0.0000000000000000000000000000000000769 150.0
TLS3_k127_3401514_22 Two component regulator propeller - - - 0.00000000000000000000000000000002091 141.0
TLS3_k127_3401514_23 metallopeptidase activity - - - 0.000000000000000000000004204 119.0
TLS3_k127_3401514_24 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000005448 115.0
TLS3_k127_3401514_25 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000006024 96.0
TLS3_k127_3401514_27 M6 family metalloprotease domain protein - - - 0.000000000001546 81.0
TLS3_k127_3401514_28 Erythromycin esterase K06880 - - 0.0000000001572 73.0
TLS3_k127_3401514_29 Domain of unknown function (DUF4293) - - - 0.000002971 55.0
TLS3_k127_3401514_3 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II K01835 - 5.4.2.2 9.081e-224 700.0
TLS3_k127_3401514_30 Lysyl oxidase - - - 0.00001991 58.0
TLS3_k127_3401514_31 addiction module antidote protein HigA - - - 0.00004733 48.0
TLS3_k127_3401514_32 - - - - 0.000539 43.0
TLS3_k127_3401514_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 8.357e-215 674.0
TLS3_k127_3401514_5 PFAM Aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 550.0
TLS3_k127_3401514_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 497.0
TLS3_k127_3401514_7 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 372.0
TLS3_k127_3401514_8 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 312.0
TLS3_k127_3401514_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
TLS3_k127_3439106_0 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003714 278.0
TLS3_k127_3439106_1 Universal stress protein family - - - 0.000000000000000000000000335 115.0
TLS3_k127_344863_0 usher protein - - - 0.0 1607.0
TLS3_k127_344863_1 TIGRFAM RHS repeat-associated core domain - - - 0.0 1266.0
TLS3_k127_344863_10 - - - - 0.00000000000000000000001009 114.0
TLS3_k127_344863_11 - - - - 0.000000000000001702 84.0
TLS3_k127_344863_12 Outer membrane protein (OmpH-like) K06142 - - 0.000000000004225 72.0
TLS3_k127_344863_13 - - - - 0.00000000009761 68.0
TLS3_k127_344863_14 - - - - 0.000000001683 65.0
TLS3_k127_344863_15 - - - - 0.00000003129 66.0
TLS3_k127_344863_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 576.0
TLS3_k127_344863_3 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 498.0
TLS3_k127_344863_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 355.0
TLS3_k127_344863_5 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000006378 211.0
TLS3_k127_344863_6 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000227 154.0
TLS3_k127_344863_7 - - - - 0.0000000000000000000000000000000000003994 152.0
TLS3_k127_344863_8 cellulase activity - - - 0.00000000000000000000000000000001038 139.0
TLS3_k127_344863_9 Prokaryotic N-terminal methylation motif K02655 - - 0.0000000000000000000000000000003932 126.0
TLS3_k127_3461755_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000002383 233.0
TLS3_k127_3461755_1 Domain of unknown function (DUF4411) - - - 0.00000000000000000000000000000000000007733 147.0
TLS3_k127_3461755_2 Alpha beta hydrolase - - - 0.00000000000000000000000000005507 125.0
TLS3_k127_3461755_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000001591 102.0
TLS3_k127_3461755_4 IrrE N-terminal-like domain - - - 0.0003157 46.0
TLS3_k127_3472544_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 454.0
TLS3_k127_3472544_1 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 419.0
TLS3_k127_3472544_2 GDSL family lipolytic protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 391.0
TLS3_k127_3472544_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
TLS3_k127_3472544_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
TLS3_k127_3472544_5 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K15460 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223 0.0000000000000000000000000000000000000000000002374 175.0
TLS3_k127_3529685_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 526.0
TLS3_k127_3529685_2 - - - - 0.00000000000000000000000001103 112.0
TLS3_k127_3529685_3 Domain of unknown function (DUF4476) - - - 0.0000006902 57.0
TLS3_k127_3529685_4 Collagen triple helix repeat - - - 0.00002694 57.0
TLS3_k127_3624809_0 ApbE family K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000009474 164.0
TLS3_k127_3624809_1 Periplasmic Protein - - - 0.00000000000000000000000000000000001172 146.0
TLS3_k127_3624809_2 Tetratricopeptide repeat - - - 0.000000000000005524 83.0
TLS3_k127_3624809_3 COG5337 Spore coat assembly protein - - - 0.000001356 51.0
TLS3_k127_3624895_0 PFAM PKD domain - - - 2.99e-254 801.0
TLS3_k127_3630739_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.482e-271 852.0
TLS3_k127_3630739_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.227e-214 670.0
TLS3_k127_3666176_0 DHH family K07462 - - 1.508e-198 634.0
TLS3_k127_3666176_1 SprB repeat - - - 6.952e-198 666.0
TLS3_k127_3666176_2 Helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 493.0
TLS3_k127_3666176_3 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 299.0
TLS3_k127_3666176_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000802 148.0
TLS3_k127_3666176_5 PKD domain containing protein - - - 0.000000000000002273 92.0
TLS3_k127_3667001_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000004407 193.0
TLS3_k127_3667001_1 histidine kinase A domain protein - - - 0.00000000000000000000000000001527 128.0
TLS3_k127_3667001_2 Conserved repeat domain - - - 0.0000000000000000001146 98.0
TLS3_k127_3674958_0 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 612.0
TLS3_k127_3674958_1 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 328.0
TLS3_k127_3674958_2 COG4206 Outer membrane cobalamin receptor protein K02014 - - 0.000000000000000000000000000000000000000000000000000000000002031 224.0
TLS3_k127_3680650_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 570.0
TLS3_k127_3680650_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
TLS3_k127_3684009_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01955 - 6.3.5.5 0.0 1733.0
TLS3_k127_3684009_1 PFAM Bacterial membrane protein YfhO - - - 3.673e-304 961.0
TLS3_k127_3684009_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
TLS3_k127_3684009_3 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000001167 158.0
TLS3_k127_3684009_4 Cytidylyltransferase K07257,K21750 - 2.7.7.92 0.000000000000000000000004461 105.0
TLS3_k127_3749536_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 594.0
TLS3_k127_3749536_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 480.0
TLS3_k127_3749536_2 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 319.0
TLS3_k127_3749536_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 300.0
TLS3_k127_3761958_0 Belongs to the ompA family - - - 1.202e-291 919.0
TLS3_k127_3761958_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.391e-213 669.0
TLS3_k127_3761958_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 497.0
TLS3_k127_3761958_3 Polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000796 184.0
TLS3_k127_3761958_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000002217 173.0
TLS3_k127_3761958_5 - - - - 0.000000000000000000000000005559 127.0
TLS3_k127_3761958_6 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.00000000000003459 74.0
TLS3_k127_3761958_8 Putative zinc-finger - - - 0.00009953 48.0
TLS3_k127_377071_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 346.0
TLS3_k127_377071_1 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000009022 183.0
TLS3_k127_377071_2 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000008336 164.0
TLS3_k127_377071_3 Cupin domain - - - 0.000000000000000000000000002412 116.0
TLS3_k127_3814392_0 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1099.0
TLS3_k127_3814392_1 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 587.0
TLS3_k127_3814392_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 406.0
TLS3_k127_3814392_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
TLS3_k127_3814392_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000001585 210.0
TLS3_k127_3814392_5 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000001197 143.0
TLS3_k127_3814392_6 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000003595 130.0
TLS3_k127_3814392_7 ThiS family K03154 - - 0.0000000438 57.0
TLS3_k127_383735_0 Sodium/hydrogen exchanger family - - - 1.914e-296 917.0
TLS3_k127_383735_1 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 446.0
TLS3_k127_383735_2 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 432.0
TLS3_k127_383735_3 Pfam Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000003815 214.0
TLS3_k127_383735_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000001108 186.0
TLS3_k127_3839127_0 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
TLS3_k127_3839127_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 289.0
TLS3_k127_3839127_2 Deoxyuridine 5'-triphosphate nucleotidohydrolase - - - 0.0000000000000000000000000000000000005975 141.0
TLS3_k127_3839127_3 OsmC-like protein - - - 0.0000000002805 62.0
TLS3_k127_3889749_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.0 1010.0
TLS3_k127_3889749_1 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002334 249.0
TLS3_k127_3889749_2 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000001904 197.0
TLS3_k127_3889749_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000001639 164.0
TLS3_k127_3889749_4 domain, Protein - - - 0.00000000000000000000000000000000000000227 159.0
TLS3_k127_3889749_5 PFAM transposase IS3 IS911 family protein - - - 0.000000000000000000000000004073 113.0
TLS3_k127_3934420_0 Fungalysin metallopeptidase (M36) - - - 6.975e-266 864.0
TLS3_k127_3934420_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 550.0
TLS3_k127_3934420_2 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
TLS3_k127_3934420_3 PFAM PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 362.0
TLS3_k127_3942026_0 C-terminal domain of CHU protein family - - - 7.542e-320 1007.0
TLS3_k127_3942026_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 361.0
TLS3_k127_3942026_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000003634 157.0
TLS3_k127_3942078_0 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 8.181e-195 616.0
TLS3_k127_3942078_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 595.0
TLS3_k127_3942078_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 279.0
TLS3_k127_3942078_3 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000008021 247.0
TLS3_k127_3942078_4 guanyl-nucleotide exchange factor activity - - - 0.0000000000000001467 95.0
TLS3_k127_3952947_0 Ribulose-phosphate 3 epimerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 433.0
TLS3_k127_3952947_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
TLS3_k127_397722_0 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 401.0
TLS3_k127_397722_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000005519 210.0
TLS3_k127_397722_2 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000156 150.0
TLS3_k127_397722_3 MORN repeat variant - - - 0.000000000000000000000000000001328 136.0
TLS3_k127_397722_4 - - - - 0.00001778 53.0
TLS3_k127_4006543_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 542.0
TLS3_k127_4006543_1 Homoserine dehydrogenase, NAD binding domain K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 450.0
TLS3_k127_4006543_2 Sulphur transport K07112 - - 0.000000000000000000000000000000001734 134.0
TLS3_k127_4006543_3 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000003587 125.0
TLS3_k127_4006543_4 OsmC-like protein K07397 - - 0.00000000000000000000000000002003 121.0
TLS3_k127_4006543_5 ABC transporter transmembrane region - - - 0.0000000000000000007119 88.0
TLS3_k127_4013421_0 CotH kinase protein - - - 0.0 1260.0
TLS3_k127_4013421_1 Tetratricopeptide repeat - - - 3.709e-292 929.0
TLS3_k127_4013421_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 380.0
TLS3_k127_4013421_11 protein CHP03519, membrane, Bacteroidetes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 379.0
TLS3_k127_4013421_12 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 379.0
TLS3_k127_4013421_13 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
TLS3_k127_4013421_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 323.0
TLS3_k127_4013421_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
TLS3_k127_4013421_16 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 301.0
TLS3_k127_4013421_17 ATPases associated with a variety of cellular activities K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 294.0
TLS3_k127_4013421_18 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 287.0
TLS3_k127_4013421_19 Psort location Cytoplasmic, score 8.96 K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000001967 226.0
TLS3_k127_4013421_2 Receptor - - - 1.282e-194 623.0
TLS3_k127_4013421_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004547 232.0
TLS3_k127_4013421_21 Molecular chaperone DnaK - - - 0.00000000000000000000000000000000000000000000000000004012 190.0
TLS3_k127_4013421_22 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000342 198.0
TLS3_k127_4013421_23 GldH lipoprotein - GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000601 172.0
TLS3_k127_4013421_25 Chaperone of endosialidase - - - 0.0000000000000000000000000000001183 136.0
TLS3_k127_4013421_26 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000682 130.0
TLS3_k127_4013421_27 - - - - 0.0000000000000000000000000000435 120.0
TLS3_k127_4013421_29 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000004264 116.0
TLS3_k127_4013421_3 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 596.0
TLS3_k127_4013421_30 Protein of unknown function (DUF2847) - - - 0.0000000000000000000000002067 110.0
TLS3_k127_4013421_31 - - - - 0.0000000000000000000008993 100.0
TLS3_k127_4013421_33 - - - - 0.0000000000004474 72.0
TLS3_k127_4013421_34 Glycosyl hydrolases family 16 - - - 0.000000000001576 77.0
TLS3_k127_4013421_37 - - - - 0.00000002512 63.0
TLS3_k127_4013421_38 helix_turn_helix, Lux Regulon - - - 0.000007515 57.0
TLS3_k127_4013421_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 530.0
TLS3_k127_4013421_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 475.0
TLS3_k127_4013421_6 TIGRFAM DNA polymerase III, delta' subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 457.0
TLS3_k127_4013421_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 447.0
TLS3_k127_4013421_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 452.0
TLS3_k127_4013421_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 394.0
TLS3_k127_4017822_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.786e-294 908.0
TLS3_k127_4017822_1 peptidase S9 prolyl oligopeptidase active site domain protein - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.328e-283 887.0
TLS3_k127_4017822_10 Tryptophan halogenase K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000005756 273.0
TLS3_k127_4017822_11 PFAM Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000965 229.0
TLS3_k127_4017822_12 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000000001865 198.0
TLS3_k127_4017822_13 - - - - 0.0000000000000000000000000000000000000000000000000002587 198.0
TLS3_k127_4017822_14 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000002692 190.0
TLS3_k127_4017822_15 Cytidylyltransferase-like K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000004545 176.0
TLS3_k127_4017822_16 - - - - 0.0000000000000000000000000000000000000000000002889 176.0
TLS3_k127_4017822_17 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000000000000000000000000000000000000000071 173.0
TLS3_k127_4017822_18 Protein of unknown function (DUF3822) - - - 0.0000000000000000000004288 106.0
TLS3_k127_4017822_2 - - - - 2.975e-275 868.0
TLS3_k127_4017822_20 Nodulation protein S (NodS) - - - 0.00000006303 63.0
TLS3_k127_4017822_21 COG NOG19144 non supervised orthologous group - - - 0.000008368 57.0
TLS3_k127_4017822_22 - - - - 0.0001207 47.0
TLS3_k127_4017822_23 - - - - 0.0004641 51.0
TLS3_k127_4017822_3 UvrD-like helicase C-terminal domain K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 489.0
TLS3_k127_4017822_4 COGs COG1033 exporter of the RND superfamily protein K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 422.0
TLS3_k127_4017822_5 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 428.0
TLS3_k127_4017822_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 404.0
TLS3_k127_4017822_7 conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 295.0
TLS3_k127_4017822_8 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
TLS3_k127_4017822_9 Psort location CytoplasmicMembrane, score 10.00 K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000004396 265.0
TLS3_k127_4028174_0 sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 322.0
TLS3_k127_4028174_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000005157 235.0
TLS3_k127_4028174_2 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000002421 204.0
TLS3_k127_4028174_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000006991 195.0
TLS3_k127_4028174_4 - - - - 0.0000000000000000000000000000000000009777 145.0
TLS3_k127_4028174_5 YbaB/EbfC DNA-binding family K09747 - - 0.00004465 50.0
TLS3_k127_4040598_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 498.0
TLS3_k127_4040598_1 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 271.0
TLS3_k127_4049798_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001671 258.0
TLS3_k127_4049798_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000003957 216.0
TLS3_k127_4049798_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00005869 48.0
TLS3_k127_4068826_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
TLS3_k127_4068826_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003069 239.0
TLS3_k127_4068826_2 NAD(P)H-binding - - - 0.0000000000000000001178 91.0
TLS3_k127_4068826_3 citrate synthase K01647 - 2.3.3.1 0.0000000003031 60.0
TLS3_k127_409306_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 316.0
TLS3_k127_409306_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000007069 219.0
TLS3_k127_409306_2 PFAM NAD dependent epimerase dehydratase family K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000001638 139.0
TLS3_k127_414522_0 CarboxypepD_reg-like domain - - - 0.0 1104.0
TLS3_k127_414522_1 Domain of unknown function (DUF4249) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 417.0
TLS3_k127_414522_2 Rhodanese Homology Domain - - - 0.000000000000000000000009157 104.0
TLS3_k127_414522_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000009492 79.0
TLS3_k127_4222815_0 HNH endonuclease - - - 0.000000000000000000006195 97.0
TLS3_k127_4222815_1 Response regulator of the LytR AlgR family - - - 0.0000000000000001604 89.0
TLS3_k127_4222815_3 Lipopolysaccharide assembly protein A domain - - - 0.0002564 48.0
TLS3_k127_4222815_4 Tetratricopeptide repeats - - - 0.0005214 50.0
TLS3_k127_422774_0 PFAM tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.859e-299 924.0
TLS3_k127_422774_1 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 445.0
TLS3_k127_422774_2 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
TLS3_k127_422774_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
TLS3_k127_422774_4 DNA-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 327.0
TLS3_k127_422774_6 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000009268 168.0
TLS3_k127_422774_7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000002484 92.0
TLS3_k127_422774_8 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000001258 79.0
TLS3_k127_4229269_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 592.0
TLS3_k127_4229269_1 FMN-dependent dehydrogenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 488.0
TLS3_k127_4229269_2 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 409.0
TLS3_k127_4229269_3 C-terminal domain of CHU protein family - - - 0.0000000000000000000002483 98.0
TLS3_k127_4229585_0 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 510.0
TLS3_k127_4229585_1 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001873 273.0
TLS3_k127_4229585_2 MgtE intracellular N domain K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001139 245.0
TLS3_k127_4229585_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000002342 107.0
TLS3_k127_4229585_4 - - - - 0.0000000000000002762 79.0
TLS3_k127_4232923_0 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 347.0
TLS3_k127_4232923_1 SprB repeat - - - 0.0000000000000000000000000000000000000000000000000000000002289 220.0
TLS3_k127_4232923_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000001464 206.0
TLS3_k127_4232923_3 PFAM Phage Tail Collar - - - 0.00000000000000000000000000000000000000000000001749 176.0
TLS3_k127_4232923_4 PFAM phage Tail Collar domain - - - 0.00000000000000000000000000000000000000000000003015 176.0
TLS3_k127_4232923_5 PFAM phage Tail Collar domain - - - 0.000000000000000000000000000000000000000000104 165.0
TLS3_k127_4251914_0 PFAM Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.0 1054.0
TLS3_k127_4251914_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 542.0
TLS3_k127_4251914_2 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001472 278.0
TLS3_k127_4251914_3 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000004121 196.0
TLS3_k127_4251914_4 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000008236 154.0
TLS3_k127_4251914_5 - - - - 0.00000000000000000000000006929 119.0
TLS3_k127_4368447_0 PFAM Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001229 277.0
TLS3_k127_4368447_1 membrane K08974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
TLS3_k127_443504_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 527.0
TLS3_k127_443504_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006968 275.0
TLS3_k127_443504_2 Damage-inducible protein DinB - - - 0.00000000000000000000000000000000000000000000003284 175.0
TLS3_k127_4443070_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 7.823e-242 755.0
TLS3_k127_4443070_1 TamB, inner membrane protein subunit of TAM complex - - - 2.854e-232 763.0
TLS3_k127_4443070_2 LVIVD repeat - - - 0.0000457 55.0
TLS3_k127_4467910_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0 1005.0
TLS3_k127_4467910_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001703 269.0
TLS3_k127_4467910_2 - - - - 0.00000000000000000000000000000000000000000000000000000002156 213.0
TLS3_k127_4467910_3 Glycosyl hydrolases family 18 - - - 0.000000000000000000000000000000000000000000000000001353 207.0
TLS3_k127_4467910_4 Pfam Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000006233 180.0
TLS3_k127_4467910_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000002967 166.0
TLS3_k127_4467910_6 Belongs to the peptidase S8 family - - - 0.00000000000000000009702 105.0
TLS3_k127_4496695_0 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
TLS3_k127_4496695_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
TLS3_k127_4496695_2 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000001739 214.0
TLS3_k127_4496695_3 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000003419 177.0
TLS3_k127_4496695_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000002204 145.0
TLS3_k127_4535969_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.945e-255 792.0
TLS3_k127_4535969_1 PPIC-type PPIASE domain K03771 - 5.2.1.8 1.467e-254 801.0
TLS3_k127_4535969_2 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
TLS3_k127_4535969_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000005584 156.0
TLS3_k127_4535969_4 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.000000000000000000000000003705 114.0
TLS3_k127_4535969_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000007291 82.0
TLS3_k127_4564374_0 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 330.0
TLS3_k127_4564374_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000002814 144.0
TLS3_k127_457785_0 Domain of unknown function (DUF4440) - - - 5.906e-228 715.0
TLS3_k127_457785_1 FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004588 244.0
TLS3_k127_457785_2 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002831 227.0
TLS3_k127_457785_3 - - - - 0.00000000000000000000000000003111 117.0
TLS3_k127_4578769_0 Peptidase S46 - - - 7.577e-266 835.0
TLS3_k127_4578769_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.953e-242 754.0
TLS3_k127_4578769_10 Pfam PAP2 superfamily - - - 0.00000000000000000000000000002289 126.0
TLS3_k127_4578769_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003985 260.0
TLS3_k127_4578769_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000051 252.0
TLS3_k127_4578769_4 ZIP Zinc transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
TLS3_k127_4578769_5 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000000007421 206.0
TLS3_k127_4578769_6 Domain of unknown function (DUF1987) - - - 0.00000000000000000000000000000000000000000000000000005207 189.0
TLS3_k127_4578769_7 - - - - 0.0000000000000000000000000000000000000000000000000002431 190.0
TLS3_k127_4578769_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000003517 170.0
TLS3_k127_4578769_9 - - - - 0.000000000000000000000000000000000000000000006442 171.0
TLS3_k127_4594794_0 PFAM Elongation factor Tu domain 2 K06207 - - 0.0 1030.0
TLS3_k127_4594794_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 6.628e-200 634.0
TLS3_k127_4616642_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1209.0
TLS3_k127_4616642_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 2.878e-207 649.0
TLS3_k127_4616642_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 389.0
TLS3_k127_4616642_3 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 343.0
TLS3_k127_4616642_4 sh3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000005775 207.0
TLS3_k127_4616642_5 sh3 domain protein K02450 - - 0.00000000000000000000000000000000000000000000000001071 192.0
TLS3_k127_4616642_6 sh3 domain protein - - - 0.0000000000000000000000000000000000000000005495 170.0
TLS3_k127_4616642_7 DoxX-like family - - - 0.00000000000000000000000005405 112.0
TLS3_k127_4622535_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1250.0
TLS3_k127_4622535_1 YHYH protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 385.0
TLS3_k127_4656547_0 Starch synthase catalytic domain K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 387.0
TLS3_k127_4656547_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 302.0
TLS3_k127_4656547_2 Domain of unknown function (DUF4270) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 249.0
TLS3_k127_4666248_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.744e-225 716.0
TLS3_k127_4666248_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 464.0
TLS3_k127_4666248_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002059 274.0
TLS3_k127_4666248_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000888 270.0
TLS3_k127_4666248_4 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.00000000000000000000000000000000000000000000000000000000000002488 220.0
TLS3_k127_4666248_5 - - - - 0.000000000000000000000000000000000000000000005036 185.0
TLS3_k127_4666248_6 PKD domain - - - 0.000000000009105 78.0
TLS3_k127_4701905_0 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 511.0
TLS3_k127_4701905_1 microcin C7 resistance K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
TLS3_k127_4701905_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
TLS3_k127_4701905_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000004334 223.0
TLS3_k127_4701905_4 - - - - 0.0000000000000000000000000000000000000000000000001181 184.0
TLS3_k127_4726386_0 Histidine kinase - - - 0.0 1009.0
TLS3_k127_4726386_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 436.0
TLS3_k127_4726386_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005225 290.0
TLS3_k127_4726386_3 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000001006 198.0
TLS3_k127_4726386_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000004483 208.0
TLS3_k127_4726386_5 Peptidase family C25 - - - 0.000000000000000000000005982 111.0
TLS3_k127_4726386_6 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.00000001187 66.0
TLS3_k127_4726386_8 Gliding motility-associated C-terminal domain - - - 0.00002453 55.0
TLS3_k127_4729333_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.547e-298 929.0
TLS3_k127_4735536_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 3.573e-277 872.0
TLS3_k127_4735536_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 8.596e-201 634.0
TLS3_k127_4735536_2 Y_Y_Y domain - - - 2.736e-196 637.0
TLS3_k127_4735536_3 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 448.0
TLS3_k127_4735536_4 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 357.0
TLS3_k127_4735536_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 307.0
TLS3_k127_4735536_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
TLS3_k127_4744540_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 511.0
TLS3_k127_4744540_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 486.0
TLS3_k127_4751108_0 Peptidase family C25 - - - 0.0 1211.0
TLS3_k127_4751108_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 4.476e-202 632.0
TLS3_k127_4751108_2 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 477.0
TLS3_k127_4751108_3 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 351.0
TLS3_k127_4751108_4 YgbB family K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000006731 231.0
TLS3_k127_4751108_5 Type IX secretion system membrane protein PorP/SprF - - - 0.000004673 49.0
TLS3_k127_4751108_6 - - - - 0.00008658 49.0
TLS3_k127_4761000_0 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 541.0
TLS3_k127_4761000_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 365.0
TLS3_k127_4761000_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000004108 258.0
TLS3_k127_4761000_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000001115 177.0
TLS3_k127_4768457_0 Chorismate mutase type II K04516 - 5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 288.0
TLS3_k127_4768457_1 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003357 264.0
TLS3_k127_4768457_2 Transcriptional regulatory protein, C terminal - - - 0.0000005732 51.0
TLS3_k127_4768457_3 - - - - 0.000008166 53.0
TLS3_k127_4770463_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 504.0
TLS3_k127_4770463_1 unidirectional conjugation K03205 - - 0.00000000000000000001956 105.0
TLS3_k127_4770463_2 Pkd domain containing protein - - - 0.0000002335 65.0
TLS3_k127_4793641_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 437.0
TLS3_k127_4793641_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 428.0
TLS3_k127_4793641_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 319.0
TLS3_k127_4793641_3 endonuclease I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003895 278.0
TLS3_k127_4793641_4 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000009885 239.0
TLS3_k127_4793641_5 OmpA family - - - 0.0000000000000000000000000000000000000000000000000002939 192.0
TLS3_k127_4793641_6 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000002786 174.0
TLS3_k127_4793641_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000004332 159.0
TLS3_k127_4793641_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000002587 127.0
TLS3_k127_479858_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 463.0
TLS3_k127_479858_1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 414.0
TLS3_k127_479858_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 380.0
TLS3_k127_479858_3 chorismate binding enzyme K02361,K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000003178 224.0
TLS3_k127_479858_4 Thioesterase superfamily K19222 - 3.1.2.28 0.00000000000000000000000000000000000000000000000000006611 189.0
TLS3_k127_479858_5 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000002423 179.0
TLS3_k127_479858_6 Belongs to the peptidase S8 family - - - 0.0000000000000000000000008017 119.0
TLS3_k127_479858_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000003841 106.0
TLS3_k127_479858_8 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000003831 84.0
TLS3_k127_4804863_0 Two component regulator propeller - - - 7.22e-252 828.0
TLS3_k127_4804863_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 461.0
TLS3_k127_4804863_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 423.0
TLS3_k127_4804863_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 362.0
TLS3_k127_4804863_4 Metalloenzyme superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 317.0
TLS3_k127_4804863_5 Penicillin-insensitive murein endopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001674 238.0
TLS3_k127_4804863_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000001425 221.0
TLS3_k127_4804863_7 - - - - 0.0000000000000000000000000000000000000000000000000000000002556 204.0
TLS3_k127_4804863_8 Pfam 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001449 156.0
TLS3_k127_4804863_9 Psort location CytoplasmicMembrane, score - - - 0.000000000001632 77.0
TLS3_k127_4811654_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 407.0
TLS3_k127_4811654_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 315.0
TLS3_k127_4818612_0 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 293.0
TLS3_k127_4818612_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000007403 199.0
TLS3_k127_4818612_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000001876 197.0
TLS3_k127_4824988_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 499.0
TLS3_k127_4824988_1 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000001031 181.0
TLS3_k127_4824988_2 T4-like virus tail tube protein gp19 - - - 0.0000000001858 67.0
TLS3_k127_4864546_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 6.037e-195 615.0
TLS3_k127_4864546_1 TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 427.0
TLS3_k127_4864546_2 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 353.0
TLS3_k127_4864546_3 PFAM PKD domain - - - 0.0000000000000000000000007997 116.0
TLS3_k127_4884129_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.47e-254 788.0
TLS3_k127_4884129_1 ABC-type multidrug transport system ATPase and permease K18890 - - 1.526e-239 754.0
TLS3_k127_4884129_10 - - - - 0.0000000000000000000000000000000000000000000000002904 179.0
TLS3_k127_4884129_11 response to oxidative stress K04063 - - 0.000000000000000000000000000000000000000000834 161.0
TLS3_k127_4884129_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 527.0
TLS3_k127_4884129_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 486.0
TLS3_k127_4884129_4 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 439.0
TLS3_k127_4884129_5 PFAM Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 439.0
TLS3_k127_4884129_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 308.0
TLS3_k127_4884129_7 Uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 300.0
TLS3_k127_4884129_8 heat shock protein binding K03686,K05801,K17867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006673 268.0
TLS3_k127_4884129_9 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000002368 233.0
TLS3_k127_4922054_0 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer K09952 - - 3.444e-277 897.0
TLS3_k127_4922054_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 331.0
TLS3_k127_4922054_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.000000000000000000000000000000000000000000002966 166.0
TLS3_k127_4931106_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 469.0
TLS3_k127_4931106_1 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 349.0
TLS3_k127_4945334_0 Fe-S oxidoreductase - - - 0.0 1148.0
TLS3_k127_4945334_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000000003346 188.0
TLS3_k127_4948903_0 Carbohydrate family 9 binding domain-like - - - 2.859e-201 653.0
TLS3_k127_4948903_1 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000904 242.0
TLS3_k127_4948903_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000001647 199.0
TLS3_k127_4953923_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.035e-265 825.0
TLS3_k127_4953923_1 HI0933 family K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 583.0
TLS3_k127_4953923_2 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 322.0
TLS3_k127_4953923_3 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000002672 188.0
TLS3_k127_4953923_5 - - - - 0.000000000000000001847 94.0
TLS3_k127_4972972_0 COG0457 FOG TPR repeat - - - 1.541e-215 682.0
TLS3_k127_4972972_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.398e-211 663.0
TLS3_k127_4972972_10 Outer membrane protein beta-barrel domain - - - 0.00000000000000000009802 92.0
TLS3_k127_4972972_11 YceI-like domain - - - 0.000000000000005696 89.0
TLS3_k127_4972972_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 403.0
TLS3_k127_4972972_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 336.0
TLS3_k127_4972972_4 Protein of unknown function (DUF2797) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
TLS3_k127_4972972_5 Gliding motility protein, GldB - - - 0.00000000000000000000000000000000000000000000000000000000000000000002049 244.0
TLS3_k127_4972972_6 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000009509 203.0
TLS3_k127_4972972_7 transferase activity, transferring glycosyl groups K07011,K13659 - 2.4.1.264 0.00000000000000000000000000000000000000000000000000001352 203.0
TLS3_k127_4972972_8 Gliding motility protein GldC - - - 0.000000000000000000000000000000000000000000000000007587 182.0
TLS3_k127_4972972_9 cellulose binding - - - 0.0000000000000000000000000000000000000000002859 180.0
TLS3_k127_4973891_0 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 494.0
TLS3_k127_4973891_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005938 284.0
TLS3_k127_4973891_10 - K03929,K12287 - - 0.0001941 54.0
TLS3_k127_4973891_2 SPTR CHU large protein - - - 0.0000000000000000000000000000000000000000006381 177.0
TLS3_k127_4973891_3 TIGRFAM single stranded DNA-binding protein (ssb) K03111 - - 0.000000000000000000000000000000000000000008703 156.0
TLS3_k127_4973891_4 Gliding motility protein RemB - - - 0.000000000000000000000000000000000000004592 155.0
TLS3_k127_4973891_5 domain, Protein - - - 0.000000000000000000000000000000000000149 154.0
TLS3_k127_4973891_6 Pkd domain containing protein - - - 0.0000000000000000000000000000002793 140.0
TLS3_k127_4973891_7 single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000001897 111.0
TLS3_k127_4973891_8 single-stranded DNA binding K03111 - - 0.000000000000000000000001247 108.0
TLS3_k127_4973891_9 Leucine-rich repeat (LRR) protein - - - 0.000000753 58.0
TLS3_k127_5047827_0 Glycosyl transferase family 21 K00786 - - 6.028e-275 858.0
TLS3_k127_5047827_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 343.0
TLS3_k127_5047827_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 319.0
TLS3_k127_5047827_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000006696 218.0
TLS3_k127_5047827_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000004076 197.0
TLS3_k127_5047827_5 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000003456 178.0
TLS3_k127_5047827_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000001251 128.0
TLS3_k127_5061937_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 316.0
TLS3_k127_5061937_1 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 320.0
TLS3_k127_5112223_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1104.0
TLS3_k127_5112223_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000432 146.0
TLS3_k127_514021_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 2.039e-231 719.0
TLS3_k127_514021_1 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 579.0
TLS3_k127_514021_2 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 409.0
TLS3_k127_514021_3 Belongs to the peptidase S8 family K07004,K20755 - 3.4.21.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 339.0
TLS3_k127_514021_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 304.0
TLS3_k127_514021_5 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000001218 158.0
TLS3_k127_514021_6 PFAM PKD domain - - - 0.000000000000000005805 96.0
TLS3_k127_5153348_0 Molybdopterin oxidoreductase Fe4S4 domain K00367 - 1.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
TLS3_k127_5153348_1 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
TLS3_k127_5154898_0 COGs COG3023 Negative regulator of beta-lactamase expression - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 329.0
TLS3_k127_5154898_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
TLS3_k127_5154898_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000003012 132.0
TLS3_k127_5178103_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1287.0
TLS3_k127_5178103_1 impB/mucB/samB family K02346 - 2.7.7.7 5.594e-216 674.0
TLS3_k127_5178103_2 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 610.0
TLS3_k127_5178103_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
TLS3_k127_5178103_4 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000004383 175.0
TLS3_k127_5178103_5 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000001346 111.0
TLS3_k127_5178103_6 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000008201 81.0
TLS3_k127_5178103_7 Domain in cystathionine beta-synthase and other proteins. K01895 - 6.2.1.1 0.000000003869 62.0
TLS3_k127_5178103_8 tRNA synthetase class II core domain (G, H, P, S and T) K01875 - 6.1.1.11 0.00000002225 55.0
TLS3_k127_5186144_0 HYR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 612.0
TLS3_k127_5186144_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 541.0
TLS3_k127_5186144_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 389.0
TLS3_k127_5186144_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000005212 241.0
TLS3_k127_5186144_4 Pfam:DUF3308 - - - 0.00000000000000000000000000000000000000000000000000000000000000001759 236.0
TLS3_k127_5186144_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000001284 136.0
TLS3_k127_5186144_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000003524 96.0
TLS3_k127_519057_0 COG1233 Phytoene dehydrogenase and related K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.531e-198 629.0
TLS3_k127_519057_1 Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
TLS3_k127_519057_2 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 302.0
TLS3_k127_519057_3 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000006982 170.0
TLS3_k127_519057_4 Fatty acid hydroxylase K15746 - 1.14.15.24 0.000000000000000000000002608 104.0
TLS3_k127_5234462_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006451 290.0
TLS3_k127_5234462_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
TLS3_k127_5234462_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000006236 169.0
TLS3_k127_5234462_3 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000000000000003646 173.0
TLS3_k127_5234462_4 metallopeptidase activity - - - 0.0004307 52.0
TLS3_k127_5248502_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000002011 169.0
TLS3_k127_5248502_1 Histidine kinase - - - 0.00000000000001031 82.0
TLS3_k127_5254797_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.526e-201 632.0
TLS3_k127_5254797_1 - - - - 0.000000000000000000000000000000000000000000000002279 185.0
TLS3_k127_5263515_0 phytoene K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 450.0
TLS3_k127_5263515_1 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 389.0
TLS3_k127_5263515_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000003112 243.0
TLS3_k127_5263515_3 - - - - 0.000000000000000000000000000001065 127.0
TLS3_k127_5263515_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000001407 107.0
TLS3_k127_5263515_5 Belongs to the glycosyl hydrolase family 6 K01218 - 3.2.1.78 0.0000000162 64.0
TLS3_k127_527101_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 7.55e-260 818.0
TLS3_k127_527101_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 372.0
TLS3_k127_527101_2 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000002151 64.0
TLS3_k127_5271228_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 1.056e-234 732.0
TLS3_k127_5271228_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 7.158e-211 664.0
TLS3_k127_5271228_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 499.0
TLS3_k127_5271228_3 PFAM Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
TLS3_k127_5271228_4 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 441.0
TLS3_k127_5271228_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 375.0
TLS3_k127_5271228_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 351.0
TLS3_k127_5271228_7 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000002333 141.0
TLS3_k127_5271228_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000000002266 117.0
TLS3_k127_5271228_9 Domain of unknown function (DUF4295) - - - 0.000000000000001237 77.0
TLS3_k127_528100_0 double-strand break repair - - - 1.114e-268 854.0
TLS3_k127_528100_1 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 534.0
TLS3_k127_528100_2 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 460.0
TLS3_k127_529061_0 O-succinylbenzoic acid--CoA ligase K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000394 273.0
TLS3_k127_529061_1 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.0000000000000000000000000000000001584 143.0
TLS3_k127_529061_2 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000001249 119.0
TLS3_k127_529061_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000004611 87.0
TLS3_k127_5301824_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000004541 228.0
TLS3_k127_5301824_1 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000000000000000000000000000007899 172.0
TLS3_k127_5301824_2 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000006706 149.0
TLS3_k127_5301824_3 histidine kinase A domain protein - - - 0.00000000000000000000000007439 123.0
TLS3_k127_5302722_0 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
TLS3_k127_5302722_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 282.0
TLS3_k127_5310458_0 Sodium hydrogen exchanger - - - 6.421e-294 919.0
TLS3_k127_5310458_1 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
TLS3_k127_5310458_2 FtsX-like permease family - - - 0.0000000005797 60.0
TLS3_k127_5311237_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000003778 240.0
TLS3_k127_5311237_1 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000001173 210.0
TLS3_k127_5311237_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000012 162.0
TLS3_k127_5311237_3 dioxygenase activity - - - 0.00000000000000000000000000000001001 141.0
TLS3_k127_5311237_4 Cyanobactin maturation protease, PatA PatG family - - - 0.000000000000000000000000000007902 130.0
TLS3_k127_5325183_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 5.499e-195 616.0
TLS3_k127_5325183_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 425.0
TLS3_k127_5325183_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 360.0
TLS3_k127_5325183_3 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 306.0
TLS3_k127_5325183_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 296.0
TLS3_k127_5325183_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000659 224.0
TLS3_k127_5325183_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000007731 162.0
TLS3_k127_5337811_0 homolog of phage Mu protein gp47 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 306.0
TLS3_k127_5337811_1 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000000000001355 188.0
TLS3_k127_5337811_2 PAAR motif - - - 0.00000000000000000000000000000000000000000000000003814 179.0
TLS3_k127_5337811_3 Rhs element Vgr protein - - - 0.00000000000000000000000001519 109.0
TLS3_k127_5339637_0 - - - - 1.303e-265 890.0
TLS3_k127_5339637_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 651.0
TLS3_k127_5339637_2 - - - - 0.00000000000000000000000000000000000000000000000000000000101 219.0
TLS3_k127_5339637_3 HmuY protein - - - 0.0000000000000000000000000000000000000000000000000000002524 199.0
TLS3_k127_5344209_0 Chain length determinant protein - - - 5.174e-263 833.0
TLS3_k127_5344209_1 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 526.0
TLS3_k127_5344209_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 472.0
TLS3_k127_5344209_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 364.0
TLS3_k127_5344209_4 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003073 251.0
TLS3_k127_5346904_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 448.0
TLS3_k127_5346904_1 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
TLS3_k127_5346904_2 - - - - 0.0000003774 59.0
TLS3_k127_53602_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1062.0
TLS3_k127_53602_1 NlpC/P60 family K13695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 290.0
TLS3_k127_53602_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000007622 248.0
TLS3_k127_5369346_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1054.0
TLS3_k127_5369346_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 343.0
TLS3_k127_5369346_2 Vitamin K-dependent gamma-carboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003523 274.0
TLS3_k127_5369346_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000006379 196.0
TLS3_k127_5369346_4 Belongs to the ompA family - - - 0.000000000000000000000000002862 119.0
TLS3_k127_5369346_5 Pregnancy-associated plasma protein-A - - - 0.00000001141 66.0
TLS3_k127_5371003_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 476.0
TLS3_k127_5371003_1 metallopeptidase activity K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 307.0
TLS3_k127_5371003_2 repeat protein - - - 0.00000008262 57.0
TLS3_k127_537461_0 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 471.0
TLS3_k127_5375862_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1206.0
TLS3_k127_5375862_1 Uncharacterized protein conserved in bacteria (DUF2135) - - - 8.136e-198 652.0
TLS3_k127_5375862_2 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 582.0
TLS3_k127_5375862_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 497.0
TLS3_k127_5375862_4 Sugar nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 437.0
TLS3_k127_5375862_5 - - - - 0.000000000000000000000000000000000000000000000000000000008698 203.0
TLS3_k127_5388306_0 PFAM Peptidase family M20 M25 M40 K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 543.0
TLS3_k127_5388306_1 nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 419.0
TLS3_k127_5388306_2 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 341.0
TLS3_k127_5388306_3 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000000000000001653 169.0
TLS3_k127_5388306_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000001818 140.0
TLS3_k127_5388306_6 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000008507 124.0
TLS3_k127_5388306_7 RQC K03654 - 3.6.4.12 0.00000000000000000000005974 98.0
TLS3_k127_5412415_0 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 413.0
TLS3_k127_5412415_1 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 384.0
TLS3_k127_5412415_10 positive regulation of catalytic activity in other organism involved in symbiotic interaction K14861 GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023 - 0.0001293 53.0
TLS3_k127_5412415_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 332.0
TLS3_k127_5412415_3 Na+/H+ antiporter family K03315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 334.0
TLS3_k127_5412415_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000003086 194.0
TLS3_k127_5412415_5 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000003625 201.0
TLS3_k127_5412415_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000001493 175.0
TLS3_k127_5412415_7 - - - - 0.00000000000000000000000000000000000005959 148.0
TLS3_k127_5412415_8 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000166 147.0
TLS3_k127_5412415_9 DinB family - - - 0.000000000000000001389 92.0
TLS3_k127_541748_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1139.0
TLS3_k127_541748_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.092e-250 776.0
TLS3_k127_541748_2 COGs COG3752 membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 409.0
TLS3_k127_541748_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 377.0
TLS3_k127_5425209_0 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 243.0
TLS3_k127_5429366_0 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 364.0
TLS3_k127_5429366_1 PFAM Signal transduction histidine kinase, internal region - - - 0.000000000000000000000000000178 133.0
TLS3_k127_5434924_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 494.0
TLS3_k127_5434924_1 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
TLS3_k127_5434924_10 - - - - 0.000000000000000000000000000000003254 136.0
TLS3_k127_5434924_11 Belongs to the glycosyl hydrolase 18 family K01227 - 3.2.1.96 0.0000000008929 70.0
TLS3_k127_5434924_12 MoaC family K03637 - 4.6.1.17 0.000002092 49.0
TLS3_k127_5434924_13 Domain of unknown function (DUF4157) - - - 0.0004888 47.0
TLS3_k127_5434924_2 Molybdenum Cofactor Synthesis C K03639,K20967 - 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 377.0
TLS3_k127_5434924_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 325.0
TLS3_k127_5434924_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004361 271.0
TLS3_k127_5434924_5 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000006464 205.0
TLS3_k127_5434924_6 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000000002063 194.0
TLS3_k127_5434924_7 factor 1 K13444 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0031974,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0070013,GO:0071704,GO:0120147,GO:1901135,GO:1901564,GO:1903135,GO:1903509 1.8.3.7 0.0000000000000000000000000000000000000000000000000005219 194.0
TLS3_k127_5434924_8 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000006736 181.0
TLS3_k127_5443132_0 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 607.0
TLS3_k127_5443132_1 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 575.0
TLS3_k127_5451294_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 467.0
TLS3_k127_5451294_1 molecular chaperone K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
TLS3_k127_5451294_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 294.0
TLS3_k127_5451294_3 Rifampin ADP-ribosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000075 229.0
TLS3_k127_5451294_4 amino acid racemase - - - 0.000000000000000000000000000000000000000000000000000000000007126 210.0
TLS3_k127_5451294_5 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000002045 194.0
TLS3_k127_5451294_6 - K01865 - 5.4.4.1 0.00000000000000000000000000000000000000003365 156.0
TLS3_k127_5451294_7 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000001552 125.0
TLS3_k127_5451294_8 alpha-L-arabinofuranosidase - - - 0.0003856 53.0
TLS3_k127_5465664_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 4.575e-302 933.0
TLS3_k127_5465664_1 Thioredoxin reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 324.0
TLS3_k127_5465664_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 299.0
TLS3_k127_5465664_3 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000000000000000000000006917 220.0
TLS3_k127_5465664_4 PFAM Peptidase family M13 K07386 - - 0.0000000000000000005994 89.0
TLS3_k127_5484606_0 RHS repeat-associated core domain protein - - - 8.098e-253 802.0
TLS3_k127_5494140_0 Outer membrane protein beta-barrel family - - - 1.395e-199 641.0
TLS3_k127_550702_0 Peptidase, S8 S53 family - - - 2.292e-237 753.0
TLS3_k127_550702_1 Phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 312.0
TLS3_k127_550702_2 Cytochrome c - - - 0.000001891 55.0
TLS3_k127_5524112_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 538.0
TLS3_k127_5524112_1 Peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.0000000000000000000001302 105.0
TLS3_k127_5524112_2 TraB family K09973 - - 0.00000000001628 65.0
TLS3_k127_5524112_3 - - - - 0.00002107 57.0
TLS3_k127_5524112_4 - - - - 0.00003979 53.0
TLS3_k127_5527191_0 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 491.0
TLS3_k127_5527191_1 TIGRFAM single stranded DNA-binding protein (ssb) K03111 - - 0.00000000000000000000000000000000000000000000000000000000391 203.0
TLS3_k127_5527191_2 A G-specific adenine glycosylase K03575 - - 0.00001032 50.0
TLS3_k127_5527191_3 gliding motility protein GldD - - - 0.0001485 45.0
TLS3_k127_5535763_0 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 629.0
TLS3_k127_5535763_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 410.0
TLS3_k127_5535763_2 PFAM Scaffold protein Nfu NifU N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 301.0
TLS3_k127_5535763_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001226 258.0
TLS3_k127_5535763_5 Protein of unknown function (Porph_ging) - - - 0.0000000000000000001556 98.0
TLS3_k127_5535763_6 - - - - 0.000000012 60.0
TLS3_k127_5535763_7 PFAM conserved - - - 0.0000002327 52.0
TLS3_k127_5535763_8 Metallo-peptidase family M12B Reprolysin-like - - - 0.00004194 54.0
TLS3_k127_553697_1 Endoribonuclease L-PSP K15067 - 3.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009018 269.0
TLS3_k127_553697_2 - - - - 0.00000000000000000000000000000000000000000000000004389 188.0
TLS3_k127_5538641_0 N-6 DNA Methylase - - - 7.479e-212 670.0
TLS3_k127_5538641_1 - - - - 0.000000000001081 72.0
TLS3_k127_5538641_2 Restriction endonuclease - - - 0.000000002438 68.0
TLS3_k127_5559739_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 527.0
TLS3_k127_5559739_1 adhesin AidA-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 487.0
TLS3_k127_5559739_10 Protein of unknown function (DUF1211) - - - 0.000000007035 57.0
TLS3_k127_5559739_11 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - 0.0000007388 62.0
TLS3_k127_5559739_2 Peptidase family S51 K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 323.0
TLS3_k127_5559739_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005424 266.0
TLS3_k127_5559739_4 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 249.0
TLS3_k127_5559739_5 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009405 243.0
TLS3_k127_5559739_6 Glyoxalase K04750 - - 0.00000000000000000000000000000000000000000000000000000005003 201.0
TLS3_k127_5559739_7 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000005218 181.0
TLS3_k127_5559739_8 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000004582 162.0
TLS3_k127_5559739_9 Parallel beta-helix repeats - - - 0.000000000004795 79.0
TLS3_k127_5566354_0 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 348.0
TLS3_k127_5566354_1 arginyl-trna synthetase - - - 0.00000000000000000000000000000000000000000004948 180.0
TLS3_k127_5566354_2 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000003559 163.0
TLS3_k127_5566354_3 - - - - 0.000000000000005491 79.0
TLS3_k127_5566354_4 Right handed beta helix region - - - 0.0001884 53.0
TLS3_k127_559778_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 413.0
TLS3_k127_559778_1 pectinesterase activity - - - 0.0000000000002065 76.0
TLS3_k127_5598099_0 Protein of unknown function, DUF255 K06888 - - 2.055e-219 699.0
TLS3_k127_5598099_1 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 312.0
TLS3_k127_5598099_2 NAD(P)H-binding K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005039 284.0
TLS3_k127_5598099_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000001063 204.0
TLS3_k127_5598099_5 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000000000000001488 157.0
TLS3_k127_5600310_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 558.0
TLS3_k127_5600310_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000005255 115.0
TLS3_k127_5606164_0 AcrB/AcrD/AcrF family - - - 1.104e-205 676.0
TLS3_k127_5606164_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0002582 46.0
TLS3_k127_5607603_0 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000002629 235.0
TLS3_k127_5607603_1 Restriction endonuclease - - - 0.000000000000000000000000000000000000000000000003365 182.0
TLS3_k127_5607603_2 Tetratricopeptide repeat - - - 0.00000000000000003558 94.0
TLS3_k127_5610551_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 331.0
TLS3_k127_5610551_1 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007292 262.0
TLS3_k127_5610551_2 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000002415 223.0
TLS3_k127_5610551_3 PFAM PKD domain containing protein - - - 0.0000000000000000000000000002929 133.0
TLS3_k127_5615951_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.134e-199 634.0
TLS3_k127_5615951_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 505.0
TLS3_k127_5615951_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005073 250.0
TLS3_k127_5615951_3 Protein of unknown function (DUF2795) - - - 0.00000000000000000000000000000000000001222 144.0
TLS3_k127_5662049_0 COG0471 Di- and tricarboxylate K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 350.0
TLS3_k127_5662049_1 Peroxide stress protein YaaA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
TLS3_k127_5662049_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000002238 172.0
TLS3_k127_5662049_4 Chaperone of endosialidase - - - 0.0003338 46.0
TLS3_k127_566518_0 Carboxypeptidase regulatory-like domain - - - 1.64e-317 990.0
TLS3_k127_566518_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 501.0
TLS3_k127_566518_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000006207 237.0
TLS3_k127_566518_11 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000009297 215.0
TLS3_k127_566518_12 - - - - 0.000000000000000000000000000000000000000000000000000001038 200.0
TLS3_k127_566518_13 lycopene cyclase - - - 0.00000000000000000000000000000000000000000000003237 177.0
TLS3_k127_566518_14 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000001415 168.0
TLS3_k127_566518_15 - - - - 0.000000000000000000000000000005381 131.0
TLS3_k127_566518_16 Predicted membrane protein (DUF2061) - - - 0.000000000000000000000000002319 113.0
TLS3_k127_566518_17 - - - - 0.0000000000000000000002438 97.0
TLS3_k127_566518_18 Fatty acid hydroxylase K15746 - 1.14.15.24 0.0000000000000000000003402 96.0
TLS3_k127_566518_19 Acyltransferase family - - - 0.0000001645 59.0
TLS3_k127_566518_2 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 479.0
TLS3_k127_566518_3 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 436.0
TLS3_k127_566518_4 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
TLS3_k127_566518_5 hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 320.0
TLS3_k127_566518_6 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 314.0
TLS3_k127_566518_7 aspartate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
TLS3_k127_566518_8 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 285.0
TLS3_k127_566518_9 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001255 257.0
TLS3_k127_5674952_0 - - - - 0.000000000000000000000000000000006888 138.0
TLS3_k127_5674952_2 FRG - - - 0.0000000000000001329 87.0
TLS3_k127_5674952_3 - - - - 0.000000007377 62.0
TLS3_k127_5677436_0 PFAM FG-GAP repeat - - - 1.229e-234 747.0
TLS3_k127_5677436_1 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 342.0
TLS3_k127_5677436_2 PFAM Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 318.0
TLS3_k127_5677436_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 309.0
TLS3_k127_5677436_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 278.0
TLS3_k127_5677436_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004676 266.0
TLS3_k127_5677436_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000003414 214.0
TLS3_k127_5678473_0 OmpA family - - - 2.645e-231 736.0
TLS3_k127_5678473_1 PFAM Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 456.0
TLS3_k127_5678473_2 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 300.0
TLS3_k127_5678473_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 322.0
TLS3_k127_5678473_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000007574 184.0
TLS3_k127_5678473_5 peptidase M1 K01256 - 3.4.11.2 0.00000000000000000000000000000000000000001778 159.0
TLS3_k127_5687396_0 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000001348 89.0
TLS3_k127_5687396_1 Domain of unknown function (DUF5110) - - - 0.000000000000000001366 100.0
TLS3_k127_5687396_2 Trypsin-like peptidase domain K01337 - 3.4.21.50 0.00001551 58.0
TLS3_k127_5687776_0 Berberine and berberine like - - - 1.378e-201 651.0
TLS3_k127_5687776_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 376.0
TLS3_k127_5687776_2 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 285.0
TLS3_k127_5687776_3 WG containing repeat - - - 0.0000000000000000000005801 112.0
TLS3_k127_5695519_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 522.0
TLS3_k127_5695519_1 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000001633 226.0
TLS3_k127_5695519_2 DoxX-like family - - - 0.00000000000000000000000000000000000001768 148.0
TLS3_k127_5695519_3 Peptidase M1 K01256 - 3.4.11.2 0.000000178 64.0
TLS3_k127_5695519_4 PFAM Resolvase, N-terminal - - - 0.0000001802 53.0
TLS3_k127_5695519_5 - - - - 0.0009594 44.0
TLS3_k127_5712982_0 Aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 4.519e-264 819.0
TLS3_k127_5712982_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 1.114e-232 723.0
TLS3_k127_5712982_10 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 383.0
TLS3_k127_5712982_11 MORN repeat variant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 325.0
TLS3_k127_5712982_12 response regulator, receiver K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 289.0
TLS3_k127_5712982_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000004269 229.0
TLS3_k127_5712982_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000109 220.0
TLS3_k127_5712982_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000002556 233.0
TLS3_k127_5712982_16 membrane protein (DUF2154) - - - 0.000000000000000000000000000000000000000000000000000002103 199.0
TLS3_k127_5712982_17 regulator of cell autolysis - - - 0.00000000000000000000000000000000000000000000000000001484 201.0
TLS3_k127_5712982_18 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000000001083 198.0
TLS3_k127_5712982_19 arginyl-trna synthetase - - - 0.00000000000000000000000000000000003577 147.0
TLS3_k127_5712982_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 2.967e-216 675.0
TLS3_k127_5712982_20 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000009996 138.0
TLS3_k127_5712982_21 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000001721 132.0
TLS3_k127_5712982_22 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000001045 131.0
TLS3_k127_5712982_23 glyoxalase K01759 - 4.4.1.5 0.00000000000000000000000001446 111.0
TLS3_k127_5712982_24 metallopeptidase activity - - - 0.000000005555 71.0
TLS3_k127_5712982_25 C-terminal domain of CHU protein family - - - 0.00000007341 65.0
TLS3_k127_5712982_26 - - - - 0.000001071 58.0
TLS3_k127_5712982_27 - - - - 0.000005703 54.0
TLS3_k127_5712982_3 C-terminal domain of CHU protein family - - - 6.303e-199 674.0
TLS3_k127_5712982_4 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 522.0
TLS3_k127_5712982_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 515.0
TLS3_k127_5712982_6 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 509.0
TLS3_k127_5712982_7 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 487.0
TLS3_k127_5712982_8 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 476.0
TLS3_k127_5712982_9 PFAM Uncharacterised conserved protein UCP016719 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 430.0
TLS3_k127_5715225_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2440.0
TLS3_k127_5715225_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2281.0
TLS3_k127_5715225_2 Domain of unknown function (DUF3552) K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 430.0
TLS3_k127_5715225_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 327.0
TLS3_k127_5715225_4 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000002585 143.0
TLS3_k127_5715225_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000001925 96.0
TLS3_k127_57187_0 Amidohydrolase K03392 - 4.1.1.45 3.903e-196 616.0
TLS3_k127_57187_1 SPTR Conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 331.0
TLS3_k127_5719970_0 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 359.0
TLS3_k127_5719970_1 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000000000000000000000000000006149 201.0
TLS3_k127_5719970_2 PFAM Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000007657 201.0
TLS3_k127_5719970_3 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000003791 93.0
TLS3_k127_5749895_0 ABC-type uncharacterized transport system K01992 - - 7.953e-213 676.0
TLS3_k127_5749895_1 TIGRFAM gliding motility-associated ABC transporter permease protein GldF K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 324.0
TLS3_k127_5749895_2 S-adenosyl-l-methionine hydroxide adenosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002687 241.0
TLS3_k127_5749895_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000001635 123.0
TLS3_k127_576274_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 399.0
TLS3_k127_576274_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 256.0
TLS3_k127_576274_2 Domain of unknown function (DUF4403) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007757 258.0
TLS3_k127_576274_3 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000001926 206.0
TLS3_k127_576274_4 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000004904 163.0
TLS3_k127_576274_5 cell redox homeostasis K12057 - - 0.00000000000000000000000000000000000002087 151.0
TLS3_k127_576274_6 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000006671 139.0
TLS3_k127_576274_7 - - - - 0.000000000000000007667 87.0
TLS3_k127_5777334_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 607.0
TLS3_k127_584076_0 Sulfatase-modifying factor enzyme 1 - - - 5.707e-304 935.0
TLS3_k127_584076_1 TIGRFAM gliding motility-associated protein GldM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 556.0
TLS3_k127_584076_2 Gliding motility protein GldL - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 456.0
TLS3_k127_584076_3 TIGRFAM gliding motility associated protien GldN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 438.0
TLS3_k127_584076_4 Arginase family K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 439.0
TLS3_k127_584076_5 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 308.0
TLS3_k127_584076_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000121 109.0
TLS3_k127_5877515_0 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 356.0
TLS3_k127_5877515_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004513 253.0
TLS3_k127_5877515_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001091 153.0
TLS3_k127_5877515_3 - - - - 0.000000000000000000000000008103 120.0
TLS3_k127_5877515_4 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.000000000000000004983 94.0
TLS3_k127_5877515_5 - - - - 0.00003487 47.0
TLS3_k127_5911965_0 Protein conserved in bacteria - - - 0.0 1261.0
TLS3_k127_5911965_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 552.0
TLS3_k127_5911965_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 334.0
TLS3_k127_5911965_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 315.0
TLS3_k127_5911965_4 PFAM Outer membrane protein (OmpH-like) K06142 - - 0.000000000000004538 82.0
TLS3_k127_5918204_0 PFAM Pregnancy-associated plasma protein-A - - - 9.307e-211 676.0
TLS3_k127_5918204_1 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 4.373e-198 623.0
TLS3_k127_5918204_2 PFAM Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 601.0
TLS3_k127_5918204_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 466.0
TLS3_k127_5918204_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 364.0
TLS3_k127_5918204_5 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002159 297.0
TLS3_k127_5918204_6 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008744 249.0
TLS3_k127_5918204_7 PFAM short chain dehydrogenase K16216 - 1.1.1.320 0.00000000000000000000000000000000000000002355 162.0
TLS3_k127_5918204_8 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000001415 144.0
TLS3_k127_5923258_0 COGs COG1233 Phytoene dehydrogenase and related protein K09835 - 5.2.1.13 1.158e-211 672.0
TLS3_k127_5923258_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
TLS3_k127_5923985_0 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K06959 - - 0.0 1029.0
TLS3_k127_5923985_1 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 570.0
TLS3_k127_5923985_10 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000009954 158.0
TLS3_k127_5923985_11 Outer membrane protein Omp28 - - - 0.0000000000000000002852 99.0
TLS3_k127_5923985_12 Dihaem cytochrome c - - - 0.0000000000003154 74.0
TLS3_k127_5923985_13 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000000001991 72.0
TLS3_k127_5923985_14 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.00002225 51.0
TLS3_k127_5923985_2 Outer membrane protein Omp28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 532.0
TLS3_k127_5923985_3 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 509.0
TLS3_k127_5923985_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 456.0
TLS3_k127_5923985_5 Thiazole biosynthesis protein ThiG K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 407.0
TLS3_k127_5923985_6 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 377.0
TLS3_k127_5923985_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003459 282.0
TLS3_k127_5923985_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
TLS3_k127_5923985_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003051 182.0
TLS3_k127_5962560_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 9.568e-220 686.0
TLS3_k127_5962560_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.706e-200 632.0
TLS3_k127_5962560_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.677e-200 629.0
TLS3_k127_5962560_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.994e-195 620.0
TLS3_k127_5962560_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 529.0
TLS3_k127_5962560_5 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 499.0
TLS3_k127_5962560_6 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 445.0
TLS3_k127_5962560_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 436.0
TLS3_k127_5962560_8 Cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000024 229.0
TLS3_k127_5962560_9 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000002735 224.0
TLS3_k127_6020290_0 Phosphoesterase family - - - 1.842e-225 708.0
TLS3_k127_6020290_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 539.0
TLS3_k127_6020290_2 COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
TLS3_k127_6020290_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000003577 203.0
TLS3_k127_6020290_5 - - - - 0.0000000000002362 80.0
TLS3_k127_6020290_6 long-chain fatty acid transport protein - - - 0.000000004811 69.0
TLS3_k127_6029937_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.45e-321 992.0
TLS3_k127_6029937_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.634e-211 669.0
TLS3_k127_6029937_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006052 255.0
TLS3_k127_6029937_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007797 241.0
TLS3_k127_6029937_4 integral membrane protein K07027 - - 0.000000000000000000000000000000000000000000000000000000000000005005 228.0
TLS3_k127_6029937_5 Cytidylyltransferase-like K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
TLS3_k127_6029937_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000002999 178.0
TLS3_k127_6038161_0 PFAM TonB-dependent Receptor Plug - - - 1.969e-232 743.0
TLS3_k127_6038161_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
TLS3_k127_6038161_2 GTPase activator activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000367 276.0
TLS3_k127_6038161_3 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000033 238.0
TLS3_k127_6038161_4 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000002515 149.0
TLS3_k127_6038161_5 PFAM FecR protein - - - 0.00000000000000000000000003953 120.0
TLS3_k127_6038161_6 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000005487 90.0
TLS3_k127_6081010_0 Sulfatase-modifying factor enzyme 1 - - - 0.0 1060.0
TLS3_k127_6081010_1 Glu Leu Phe Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 5.852e-225 702.0
TLS3_k127_6081010_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.769e-213 665.0
TLS3_k127_6081010_3 Na H antiporter NhaD and related arsenite - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 576.0
TLS3_k127_6081010_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 426.0
TLS3_k127_6081010_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 357.0
TLS3_k127_6081010_6 PFAM MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
TLS3_k127_6081010_7 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000007854 172.0
TLS3_k127_6081010_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000006546 100.0
TLS3_k127_6081010_9 synthase K11754 - 6.3.2.12,6.3.2.17 0.000001791 50.0
TLS3_k127_6107557_0 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000000000005595 199.0
TLS3_k127_6107557_1 - - - - 0.0000000000000000000000000000000000000000000001286 177.0
TLS3_k127_6107557_2 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000001005 109.0
TLS3_k127_6107557_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000004453 61.0
TLS3_k127_611386_0 of ABC transporters with duplicated ATPase K06158 - - 1.129e-307 947.0
TLS3_k127_611386_1 Multidrug transporter K08994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 340.0
TLS3_k127_611386_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003629 273.0
TLS3_k127_611386_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000353 258.0
TLS3_k127_611386_4 Domain of unknown function (DUF1906) - - - 0.00000000000000000000000000000000000000000000000000000000000000001939 230.0
TLS3_k127_611386_5 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000002344 190.0
TLS3_k127_611386_6 PFAM histidine kinase - - - 0.00000000000000000000000000000000000000000000001075 178.0
TLS3_k127_611386_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000001015 154.0
TLS3_k127_611386_8 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000126 67.0
TLS3_k127_611386_9 Belongs to the peptidase S8 family - - - 0.0002934 48.0
TLS3_k127_6139010_0 4Fe-4S dicluster domain K00184 - - 0.0 1412.0
TLS3_k127_6139010_1 Polysulphide reductase, NrfD K00185 - - 1.059e-298 919.0
TLS3_k127_6139010_2 PFAM Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 600.0
TLS3_k127_6139010_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
TLS3_k127_615044_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 317.0
TLS3_k127_615044_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
TLS3_k127_615044_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000009236 181.0
TLS3_k127_615044_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000001211 161.0
TLS3_k127_615044_4 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000054 144.0
TLS3_k127_615044_5 mttA/Hcf106 family K03116 - - 0.0000000000000000004816 92.0
TLS3_k127_615044_6 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000009251 96.0
TLS3_k127_6153109_0 Protein of unknown function (DUF3089) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 318.0
TLS3_k127_6153109_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000001037 210.0
TLS3_k127_6153109_2 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000006827 95.0
TLS3_k127_6153109_3 COG3209 Rhs family protein K01183 - 3.2.1.14 0.0000000000000000002627 104.0
TLS3_k127_6153109_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000443 64.0
TLS3_k127_6167240_0 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 448.0
TLS3_k127_6167240_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 449.0
TLS3_k127_6167240_2 amino acid activation for nonribosomal peptide biosynthetic process K02406 - - 0.000000000000000000000000000000000000000000368 169.0
TLS3_k127_6180149_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 444.0
TLS3_k127_6180149_1 arylsulfatase activity - - - 0.00000000000000003048 89.0
TLS3_k127_6180149_2 Peptidase family S41 K03797 - 3.4.21.102 0.000000003829 61.0
TLS3_k127_6180149_3 Histidine kinase - - - 0.00000748 52.0
TLS3_k127_6187953_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000003561 214.0
TLS3_k127_6187953_1 YdjC-like protein - - - 0.00000000000000000846 95.0
TLS3_k127_6187953_2 - - - - 0.00000000000000001611 91.0
TLS3_k127_6192761_0 WD40-like Beta Propeller Repeat - - - 1.572e-223 716.0
TLS3_k127_6192761_1 PFAM Glycosyl transferase family 2 - - - 4.55e-217 691.0
TLS3_k127_6192761_2 PFAM 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 8.174e-205 646.0
TLS3_k127_6192761_3 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000006483 189.0
TLS3_k127_6192761_4 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000007187 181.0
TLS3_k127_6194406_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1234.0
TLS3_k127_6194406_1 Domain of unknown function (DUF3362) - - - 0.0 1055.0
TLS3_k127_6194406_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000007126 210.0
TLS3_k127_6194406_11 Uncharacterized ACR, COG1399 - - - 0.000000000000000000000000000000000000000003153 163.0
TLS3_k127_6194406_12 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000009031 151.0
TLS3_k127_6194406_14 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000001971 135.0
TLS3_k127_6194406_15 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000002681 125.0
TLS3_k127_6194406_16 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000002987 145.0
TLS3_k127_6194406_17 - - - - 0.0000000000000000000000000001412 134.0
TLS3_k127_6194406_18 Putative phage abortive infection protein - - - 0.000000000000000000000000177 117.0
TLS3_k127_6194406_19 Protein of unknown function (DUF983) - - - 0.0000000000000000000000009584 108.0
TLS3_k127_6194406_2 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01961 - 6.3.4.14,6.4.1.2 2.646e-272 841.0
TLS3_k127_6194406_20 Type I site-specific restriction-modification system, R (restriction) subunit and related K01153 - 3.1.21.3 0.00000000000000000000002263 103.0
TLS3_k127_6194406_21 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000402 98.0
TLS3_k127_6194406_22 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000003227 89.0
TLS3_k127_6194406_23 - - - - 0.00000000004596 72.0
TLS3_k127_6194406_24 Type IX secretion system membrane protein PorP/SprF - - - 0.0000001292 63.0
TLS3_k127_6194406_25 Flagellar rod assembly protein muramidase FlgJ - - - 0.0000001356 58.0
TLS3_k127_6194406_26 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000737 56.0
TLS3_k127_6194406_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 570.0
TLS3_k127_6194406_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 544.0
TLS3_k127_6194406_5 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 515.0
TLS3_k127_6194406_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 489.0
TLS3_k127_6194406_7 PFAM Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 491.0
TLS3_k127_6194406_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 368.0
TLS3_k127_6194406_9 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004494 285.0
TLS3_k127_6196722_0 O-methyltransferase K07003 - - 8.547e-267 850.0
TLS3_k127_6208748_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000005326 203.0
TLS3_k127_6208748_1 - - - - 0.00000000000000000000000000000000000000000001672 167.0
TLS3_k127_6208748_2 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000002198 179.0
TLS3_k127_6208748_3 protein homooligomerization - - - 0.000000000000000000000000000004721 135.0
TLS3_k127_6208748_4 - - - - 0.00000000000003338 76.0
TLS3_k127_6212305_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 379.0
TLS3_k127_6212305_1 PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 369.0
TLS3_k127_6212305_2 glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 314.0
TLS3_k127_6212305_3 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 303.0
TLS3_k127_6212305_4 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000989 269.0
TLS3_k127_6212305_5 COG COG0381 UDP-N-acetylglucosamine 2-epimerase K13019 - 5.1.3.23 0.0000000000000000000000000000000000000000000000000007844 186.0
TLS3_k127_6212305_6 O-Antigen ligase - - - 0.000000000000000000000000000000000000000005428 170.0
TLS3_k127_6212305_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000006933 147.0
TLS3_k127_6212305_8 DNA polymerase IV (family X) K02347,K04477 - - 0.0000000000000000000000003195 113.0
TLS3_k127_6215486_0 membrane - - - 4.561e-316 993.0
TLS3_k127_6215486_1 Cytochrome C assembly protein - - - 6.965e-294 931.0
TLS3_k127_6215486_2 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 580.0
TLS3_k127_6215486_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 511.0
TLS3_k127_6215486_4 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 473.0
TLS3_k127_6232759_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 448.0
TLS3_k127_6232759_1 Domain of unknown function (DUF4835) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 371.0
TLS3_k127_6232759_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
TLS3_k127_6232759_3 RNA polymerase Rpb6 - - - 0.000000000000000000000000000000000000005267 147.0
TLS3_k127_6242780_0 PFAM Carbamoyltransferase K00612 - - 3.25e-252 807.0
TLS3_k127_6242780_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
TLS3_k127_6242780_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000001298 120.0
TLS3_k127_6242780_3 Glycosyl transferase 4-like - - - 0.000000000000000001634 98.0
TLS3_k127_6242780_4 NAD(P)H-binding K01784 - 5.1.3.2 0.00007283 48.0
TLS3_k127_6243232_0 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
TLS3_k127_6243232_1 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 362.0
TLS3_k127_6243232_10 long-chain fatty acid transporting porin activity - - - 0.000000577 61.0
TLS3_k127_6243232_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 298.0
TLS3_k127_6243232_3 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 286.0
TLS3_k127_6243232_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007168 244.0
TLS3_k127_6243232_5 PFAM Fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000004693 236.0
TLS3_k127_6243232_6 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000000005197 199.0
TLS3_k127_6243232_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000001198 169.0
TLS3_k127_6243232_8 transmembrane transport K22044 - - 0.000000000000000000000000000000000000003408 152.0
TLS3_k127_6243232_9 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000001914 142.0
TLS3_k127_6254370_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 319.0
TLS3_k127_6254370_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000005359 221.0
TLS3_k127_6254370_2 - - - - 0.000000000000000000000000000000001363 130.0
TLS3_k127_6257057_0 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1125.0
TLS3_k127_6257057_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 367.0
TLS3_k127_6282826_0 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002672 265.0
TLS3_k127_6282826_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002857 239.0
TLS3_k127_6282826_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000005181 169.0
TLS3_k127_6282826_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000123 109.0
TLS3_k127_6282826_4 Belongs to the 'phage' integrase family - - - 0.000000000000976 71.0
TLS3_k127_6282826_5 - - - - 0.00000002209 60.0
TLS3_k127_6296993_0 Sortilin, neurotensin receptor 3, - - - 0.0 1240.0
TLS3_k127_6296993_1 OmpA family - - - 3.396e-273 856.0
TLS3_k127_6296993_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 425.0
TLS3_k127_6296993_3 epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 315.0
TLS3_k127_6296993_4 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000003564 213.0
TLS3_k127_6296993_5 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000000000000000000002838 214.0
TLS3_k127_6296993_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000107 208.0
TLS3_k127_6296993_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000002061 178.0
TLS3_k127_6323082_0 efflux protein, MATE family K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 412.0
TLS3_k127_6323082_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
TLS3_k127_6323082_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 291.0
TLS3_k127_6323082_3 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000004727 256.0
TLS3_k127_6323082_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000003 233.0
TLS3_k127_6323082_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000002048 146.0
TLS3_k127_632857_0 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 330.0
TLS3_k127_632857_1 TIGRFAM branched-chain amino acid aminotransferase, group II K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 304.0
TLS3_k127_632857_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 301.0
TLS3_k127_632857_3 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000966 279.0
TLS3_k127_632857_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000004496 206.0
TLS3_k127_632857_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000007397 207.0
TLS3_k127_632857_6 PFAM Formylglycine-generating sulfatase enzyme K20276 - - 0.00000000000003579 85.0
TLS3_k127_6342041_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 492.0
TLS3_k127_6342041_1 Signal transduction histidine kinase, LytS - - - 0.000000009354 59.0
TLS3_k127_6351754_0 nuclear chromosome segregation - - - 3.066e-316 1002.0
TLS3_k127_6351754_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.619e-254 791.0
TLS3_k127_6351754_2 geranylgeranyl reductase activity - - - 1.645e-202 644.0
TLS3_k127_6351754_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 576.0
TLS3_k127_6351754_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.000000000000000000000000000000000000000003699 159.0
TLS3_k127_6351754_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000001103 157.0
TLS3_k127_6351754_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000001208 153.0
TLS3_k127_6351754_7 cellulose binding - - - 0.00000000000000000000000000000000000001601 164.0
TLS3_k127_6356647_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 401.0
TLS3_k127_6356647_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 299.0
TLS3_k127_6365735_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1463.0
TLS3_k127_6365735_1 TspO/MBR family K05770 - - 0.000000000000000000000000000000000005219 138.0
TLS3_k127_637862_0 AhpC TSA family K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 375.0
TLS3_k127_637862_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000001016 184.0
TLS3_k127_637862_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000002743 167.0
TLS3_k127_637862_3 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000006451 144.0
TLS3_k127_6381891_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 399.0
TLS3_k127_6381891_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 323.0
TLS3_k127_6384954_0 Ribonuclease E/G family K08301 - - 5.522e-266 825.0
TLS3_k127_6384954_1 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 311.0
TLS3_k127_6384954_2 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000000001901 160.0
TLS3_k127_6384954_3 Regulatory protein RecX K03565 - - 0.00000000000000000000000000000000005287 139.0
TLS3_k127_6384954_4 - - - - 0.000006361 48.0
TLS3_k127_6385790_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 554.0
TLS3_k127_6385790_1 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 452.0
TLS3_k127_6385790_10 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000000002836 118.0
TLS3_k127_6385790_11 - - - - 0.0000000000000000000002264 102.0
TLS3_k127_6385790_12 Preprotein translocase subunit K03210 - - 0.00000000000000000000127 96.0
TLS3_k127_6385790_13 Multicopper oxidase K17713,K22348 - 1.16.3.3 0.000169 53.0
TLS3_k127_6385790_2 NusB family K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 385.0
TLS3_k127_6385790_3 S4 RNA-binding domain K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 338.0
TLS3_k127_6385790_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009427 247.0
TLS3_k127_6385790_5 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002194 248.0
TLS3_k127_6385790_6 acid phosphatase activity K01727 - 4.2.2.1 0.00000000000000000000000000000000000000000000000000000000000002546 228.0
TLS3_k127_6385790_7 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000000000000000003289 179.0
TLS3_k127_6385790_8 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000001424 186.0
TLS3_k127_6385790_9 Domain of unknown function (DUF4294) - - - 0.000000000000000000000000000001507 129.0
TLS3_k127_6424911_0 regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 299.0
TLS3_k127_6424911_1 Phospholipase, patatin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 258.0
TLS3_k127_6424911_2 Domain of unknown function (DUF5110) - - - 0.0000000003742 70.0
TLS3_k127_6424911_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0003928 52.0
TLS3_k127_643819_0 Ribosomal protein L9, C-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004179 219.0
TLS3_k127_643819_1 7TMR-DISM extracellular 2 - - - 0.00000000000000000000000000000000000000000000000000000000001614 221.0
TLS3_k127_643819_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000008462 163.0
TLS3_k127_643819_3 - - - - 0.00000000000000000000003694 108.0
TLS3_k127_643819_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000526 64.0
TLS3_k127_6441214_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 423.0
TLS3_k127_6441214_2 Zn-dependent protease - - - 0.0000000000004481 74.0
TLS3_k127_6448969_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02474,K13015 - 1.1.1.136 1.897e-235 732.0
TLS3_k127_6448969_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 537.0
TLS3_k127_6448969_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 314.0
TLS3_k127_6448969_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
TLS3_k127_6448969_4 COG4464 Capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000007263 264.0
TLS3_k127_6448969_5 Tetratricopeptide repeat - - - 0.0000000000000000000000008194 120.0
TLS3_k127_6448969_6 Belongs to the UPF0312 family - - - 0.000000004556 69.0
TLS3_k127_6456166_0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 589.0
TLS3_k127_6456166_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 465.0
TLS3_k127_6474090_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 297.0
TLS3_k127_6474090_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000009059 209.0
TLS3_k127_6474090_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000005614 173.0
TLS3_k127_6474090_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000001539 124.0
TLS3_k127_6482606_0 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 555.0
TLS3_k127_6482606_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 444.0
TLS3_k127_6482606_2 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 392.0
TLS3_k127_6520_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1045.0
TLS3_k127_6520_1 metallopeptidase activity K01337 - 3.4.21.50 3.322e-275 872.0
TLS3_k127_6520_10 CutC family K06201 - - 0.0000000000000000000000000000000000000000000000001824 184.0
TLS3_k127_6520_11 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000000000008179 190.0
TLS3_k127_6520_12 Serine hydrolase (FSH1) - - - 0.0000000000000000000000000000000000000000000004655 173.0
TLS3_k127_6520_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000002002 130.0
TLS3_k127_6520_15 Hep Hag repeat protein - - - 0.000000000000000000000000000002102 137.0
TLS3_k127_6520_19 - - - - 0.00000000001988 70.0
TLS3_k127_6520_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.911e-261 809.0
TLS3_k127_6520_3 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 627.0
TLS3_k127_6520_4 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 602.0
TLS3_k127_6520_5 Phosphorylase superfamily K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 387.0
TLS3_k127_6520_6 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 338.0
TLS3_k127_6520_7 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 287.0
TLS3_k127_6520_8 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002329 283.0
TLS3_k127_6520_9 Two component transcriptional regulator, LytTR family - - - 0.00000000000000000000000000000000000000000000000000003676 193.0
TLS3_k127_6558712_0 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001215 275.0
TLS3_k127_6558712_1 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000001845 201.0
TLS3_k127_6558712_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000002386 177.0
TLS3_k127_6568709_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 379.0
TLS3_k127_6568709_1 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005799 274.0
TLS3_k127_6568709_2 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000001833 244.0
TLS3_k127_6568709_3 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000008797 209.0
TLS3_k127_6568709_4 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000042 192.0
TLS3_k127_6568709_5 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000001066 169.0
TLS3_k127_6568709_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000002454 123.0
TLS3_k127_6568709_7 ThiS family - - - 0.00003242 49.0
TLS3_k127_658421_0 TonB-dependent receptor K02014,K16089 - - 1.262e-296 928.0
TLS3_k127_658421_1 PFAM Aminotransferase class I and II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 4.112e-217 677.0
TLS3_k127_658421_2 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
TLS3_k127_658421_3 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000005221 240.0
TLS3_k127_658421_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000003889 88.0
TLS3_k127_658421_5 Tetratricopeptide repeat - - - 0.00000009616 64.0
TLS3_k127_658421_6 Secretion protein - - - 0.00006029 54.0
TLS3_k127_6591333_0 PFAM Penicillin binding protein transpeptidase domain K05366 - 2.4.1.129,3.4.16.4 5.673e-302 948.0
TLS3_k127_6591333_1 PFAM Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 9.346e-287 891.0
TLS3_k127_6591333_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.618e-245 765.0
TLS3_k127_6591333_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 2.789e-196 614.0
TLS3_k127_6591333_4 Cell cycle protein K05837 - - 7.797e-194 614.0
TLS3_k127_6591333_5 Coenzyme A transferase K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 424.0
TLS3_k127_6591333_6 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 279.0
TLS3_k127_6591333_7 rod shape-determining protein MreD - - - 0.00000000000000000000000000000000000000000000000006576 183.0
TLS3_k127_6592364_0 CarboxypepD_reg-like domain - - - 0.0 1017.0
TLS3_k127_6592364_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 410.0
TLS3_k127_6600643_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1742.0
TLS3_k127_6600643_1 Zn_pept - - - 7.67e-270 852.0
TLS3_k127_6600643_10 - - - - 0.0000000000262 71.0
TLS3_k127_6600643_11 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00006763 47.0
TLS3_k127_6600643_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 5.782e-207 662.0
TLS3_k127_6600643_3 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 608.0
TLS3_k127_6600643_4 RND transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 599.0
TLS3_k127_6600643_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 482.0
TLS3_k127_6600643_6 PFAM chorismate binding K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 352.0
TLS3_k127_6600643_7 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 340.0
TLS3_k127_6600643_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001743 278.0
TLS3_k127_6600643_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000001332 214.0
TLS3_k127_6609855_0 Oxidoreductase NAD-binding domain K00351 - 1.6.5.8 6.81e-237 737.0
TLS3_k127_6609855_1 NQR2, RnfD, RnfE family K00347 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 510.0
TLS3_k127_6609855_2 Rnf-Nqr subunit, membrane protein K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
TLS3_k127_6609855_3 domain, Protein K03570,K11904,K12132,K21471 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 345.0
TLS3_k127_6609855_4 Rnf-Nqr subunit, membrane protein K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 302.0
TLS3_k127_6609855_5 FMN_bind K00348 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000004072 236.0
TLS3_k127_6609855_6 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000003199 202.0
TLS3_k127_6609855_7 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) K00346 - 1.6.5.8 0.000000000000000000000000000000000000004422 147.0
TLS3_k127_6637894_0 Participates in initiation and elongation during chromosome replication - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 588.0
TLS3_k127_6637894_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 412.0
TLS3_k127_6637894_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 342.0
TLS3_k127_6637894_3 PFAM Response regulator receiver domain K07658 - - 0.00000000001252 64.0
TLS3_k127_6637894_4 PFAM response regulator receiver - - - 0.00008729 50.0
TLS3_k127_6661048_0 Quinol cytochrome c oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 560.0
TLS3_k127_6661048_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007881 268.0
TLS3_k127_6661048_2 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000213 185.0
TLS3_k127_6663347_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 467.0
TLS3_k127_6663347_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 391.0
TLS3_k127_6663347_2 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000009098 141.0
TLS3_k127_6664942_0 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 349.0
TLS3_k127_6664942_1 PAS domain - - - 0.00000000000000000000000000000000000000335 150.0
TLS3_k127_6664942_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000001142 145.0
TLS3_k127_6664942_4 - - - - 0.00000000002746 76.0
TLS3_k127_6664942_5 - - - - 0.0000000009315 62.0
TLS3_k127_6664942_7 - - - - 0.0000006207 59.0
TLS3_k127_6681250_0 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 384.0
TLS3_k127_6681250_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 365.0
TLS3_k127_6681250_3 Protein of unknown function (DUF1573) - - - 0.00000000000000000000000007076 113.0
TLS3_k127_6685810_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003789 259.0
TLS3_k127_6685810_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000002121 142.0
TLS3_k127_6697532_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 1.044e-229 719.0
TLS3_k127_6697532_1 TIGRFAM cytochrome c oxidase accessory protein FixG - - - 1.387e-196 622.0
TLS3_k127_6697532_2 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 399.0
TLS3_k127_6697532_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000003259 208.0
TLS3_k127_6697532_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000005171 156.0
TLS3_k127_6697532_5 FixH - - - 0.000000000000001142 85.0
TLS3_k127_6697532_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000009766 72.0
TLS3_k127_6697532_7 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000001501 64.0
TLS3_k127_6708056_0 Aromatic amino acid lyase K01745,K10774 - 4.3.1.23,4.3.1.3 4.385e-227 713.0
TLS3_k127_6708056_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 1.656e-205 644.0
TLS3_k127_6708056_2 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
TLS3_k127_6708056_3 O-methyltransferase - - - 0.0000000000000000000000000000000000001971 142.0
TLS3_k127_6708056_4 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000002005 119.0
TLS3_k127_6708056_5 PFAM Bacterial lipid A biosynthesis acyltransferase - - - 0.000000001024 60.0
TLS3_k127_6711152_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 372.0
TLS3_k127_6711152_1 AcrB/AcrD/AcrF family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 370.0
TLS3_k127_6711152_2 unusual protein kinase K03688 - - 0.0000000000000000000006581 100.0
TLS3_k127_6711152_3 Phage integrase, N-terminal SAM-like domain - - - 0.0000000001058 63.0
TLS3_k127_6717921_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 360.0
TLS3_k127_6717921_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001435 276.0
TLS3_k127_6717921_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
TLS3_k127_6717921_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004709 258.0
TLS3_k127_6717921_4 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000001679 210.0
TLS3_k127_6717921_5 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000132 128.0
TLS3_k127_6717921_6 regulation of response to stimulus - - - 0.000000008755 60.0
TLS3_k127_6717921_7 Domain of unknown function (DUF4890) - - - 0.000000202 61.0
TLS3_k127_6748760_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 544.0
TLS3_k127_6748760_1 PFAM 2Fe-2S iron-sulfur cluster binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 442.0
TLS3_k127_6748760_10 - - - - 0.00000000000002822 74.0
TLS3_k127_6748760_11 - - - - 0.000000000005569 68.0
TLS3_k127_6748760_12 Belongs to the N-Me-Phe pilin family - - - 0.0006382 49.0
TLS3_k127_6748760_2 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 430.0
TLS3_k127_6748760_3 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
TLS3_k127_6748760_4 PFAM 2Fe-2S iron-sulfur cluster binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 312.0
TLS3_k127_6748760_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004182 235.0
TLS3_k127_6748760_6 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000007125 218.0
TLS3_k127_6748760_7 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000000002175 204.0
TLS3_k127_6748760_8 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000001482 162.0
TLS3_k127_6748760_9 protein CHP03519, membrane, Bacteroidetes - - - 0.00000000000000000000000000000000000004472 155.0
TLS3_k127_675739_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
TLS3_k127_675739_1 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 326.0
TLS3_k127_675739_2 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
TLS3_k127_675739_3 Cleaved Adhesin Domain - - - 0.00000000000000000000000000000000000000000000000000000005264 205.0
TLS3_k127_675739_4 Domain of unknown function (DUF4268) - - - 0.0000000000000000000000000000000000000000000000001616 180.0
TLS3_k127_675739_5 - - - - 0.000000000000000000000000000003997 127.0
TLS3_k127_675739_6 COGs COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000008741 117.0
TLS3_k127_675739_7 Acetyltransferase (GNAT) domain - - - 0.000004433 51.0
TLS3_k127_6792442_0 peptidase M1 K01256 - 3.4.11.2 3.321e-211 665.0
TLS3_k127_6792442_1 Domain of unknown function (DUF5106) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 325.0
TLS3_k127_6797431_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 586.0
TLS3_k127_6797431_1 FdhD/NarQ family K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 345.0
TLS3_k127_6797431_2 DinB family - - - 0.000000000000000000000000001028 118.0
TLS3_k127_6799330_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 421.0
TLS3_k127_6799330_1 Protein of unknown function (DUF1361) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
TLS3_k127_6799330_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003762 279.0
TLS3_k127_6799330_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000004935 205.0
TLS3_k127_6799330_4 3D domain protein - - - 0.0000000000000000000000000000000000000000000002729 176.0
TLS3_k127_6799330_5 Psort location CytoplasmicMembrane, score K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000002686 109.0
TLS3_k127_6799330_6 Mediates influx of magnesium ions K03284 - - 0.0000000000000000009724 85.0
TLS3_k127_6799330_7 Putative MetA-pathway of phenol degradation - - - 0.0000000125 61.0
TLS3_k127_6799979_0 Aminotransferase class-V K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 435.0
TLS3_k127_6799979_1 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 379.0
TLS3_k127_6799979_10 Glycosyltransferase like family 2 - - - 0.00005131 46.0
TLS3_k127_6799979_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 362.0
TLS3_k127_6799979_3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
TLS3_k127_6799979_4 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
TLS3_k127_6799979_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002878 240.0
TLS3_k127_6799979_6 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000008396 147.0
TLS3_k127_6799979_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000002166 152.0
TLS3_k127_6799979_8 Glycosyltransferase like family 2 - - - 0.000000000003352 66.0
TLS3_k127_6799979_9 Acetyltransferase (GNAT) domain - - - 0.000000002445 67.0
TLS3_k127_6800081_0 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 548.0
TLS3_k127_6800081_1 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 377.0
TLS3_k127_6800081_2 Dialkylrecorsinol condensing enzyme DarA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 336.0
TLS3_k127_6800081_3 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000001358 237.0
TLS3_k127_6800081_4 - - - - 0.00000000000000000000000000000000000000000000000006002 181.0
TLS3_k127_6800081_5 - - - - 0.00000000000000000000000003856 114.0
TLS3_k127_681206_0 Aconitate hydratase K01681 - 4.2.1.3 0.0 1336.0
TLS3_k127_681206_1 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 527.0
TLS3_k127_681206_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000188 151.0
TLS3_k127_681206_11 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000006641 156.0
TLS3_k127_681206_12 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000000000000001912 136.0
TLS3_k127_681206_2 COG5337 Spore coat assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 540.0
TLS3_k127_681206_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 482.0
TLS3_k127_681206_4 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 312.0
TLS3_k127_681206_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 292.0
TLS3_k127_681206_6 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003446 259.0
TLS3_k127_681206_7 Protein of unknown function (DUF1573) - - - 0.00000000000000000000000000000000000000000000000000000000000001286 218.0
TLS3_k127_681206_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002094 192.0
TLS3_k127_681206_9 Protein of unknown function (DUF1573) - - - 0.00000000000000000000000000000000000000000000001272 175.0
TLS3_k127_6818885_0 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 515.0
TLS3_k127_6818885_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 516.0
TLS3_k127_6818885_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000001576 183.0
TLS3_k127_681969_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.584e-220 689.0
TLS3_k127_6824489_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1045.0
TLS3_k127_6824489_1 S1 P1 Nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 503.0
TLS3_k127_6824489_10 AAA domain, putative AbiEii toxin, Type IV TA system K09697 - 3.6.3.7 0.000000000000000004218 84.0
TLS3_k127_6824489_2 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 401.0
TLS3_k127_6824489_3 Cystathionine beta-synthase K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 375.0
TLS3_k127_6824489_4 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 305.0
TLS3_k127_6824489_5 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000001558 183.0
TLS3_k127_6824489_6 TfoX N-terminal domain - - - 0.00000000000000000000000000000000000000802 148.0
TLS3_k127_6824489_7 - - - - 0.00000000000000000000000000000000007343 141.0
TLS3_k127_6824489_8 zinc-ribbon family - - - 0.00000000000000000000000000000001454 135.0
TLS3_k127_6824489_9 TIGRFAM integral membrane protein - - - 0.0000000000000000000001663 100.0
TLS3_k127_6824986_0 Psort location OuterMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 436.0
TLS3_k127_6824986_1 YjbR - - - 0.00000000000000003302 82.0
TLS3_k127_6827839_0 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.0 1054.0
TLS3_k127_6827839_1 PFAM nucleic acid binding, OB-fold, tRNA - - - 5.821e-251 795.0
TLS3_k127_6827839_2 Bacterial capsule synthesis protein PGA_cap K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 348.0
TLS3_k127_6827839_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 345.0
TLS3_k127_6827839_4 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000005413 119.0
TLS3_k127_6842827_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 579.0
TLS3_k127_6842827_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 445.0
TLS3_k127_6842827_2 Glycosyl transferases group 1 K12989 - - 0.00000000000000000000000000000000000000000000000000000008712 209.0
TLS3_k127_6852724_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 575.0
TLS3_k127_6852724_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 284.0
TLS3_k127_6861026_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 608.0
TLS3_k127_6861026_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006872 281.0
TLS3_k127_6861026_2 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.00000000000000000000000000000000001874 144.0
TLS3_k127_6861026_3 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000003706 137.0
TLS3_k127_6865915_0 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
TLS3_k127_6865915_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 291.0
TLS3_k127_6865915_2 VTC domain - - - 0.00000000000000000000000000000000000009867 146.0
TLS3_k127_6871505_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.513e-239 745.0
TLS3_k127_6871505_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.146e-223 700.0
TLS3_k127_6871505_2 TIGRFAM Na H antiporter NhaC K03315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 571.0
TLS3_k127_6871505_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 425.0
TLS3_k127_6871505_4 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 365.0
TLS3_k127_6871505_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 366.0
TLS3_k127_6871505_6 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 324.0
TLS3_k127_6871505_7 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.0000000000000000000000000000000000000001003 153.0
TLS3_k127_688313_0 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 342.0
TLS3_k127_688313_1 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000000000000000000000002911 240.0
TLS3_k127_688313_2 Immunoglobulin-like repeats containing protein domain K20276 - - 0.00000000000000000000000000000000000000000000000003876 205.0
TLS3_k127_688313_3 Fibronectin type 3 domain - - - 0.00000000000002343 88.0
TLS3_k127_6883823_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0 1393.0
TLS3_k127_6883823_1 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000002911 201.0
TLS3_k127_6896715_0 amino acid racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 323.0
TLS3_k127_6896715_1 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000001247 189.0
TLS3_k127_6896715_2 Ribosomal subunit interface protein - - - 0.000000000000000000000000000003577 124.0
TLS3_k127_6896715_3 - - - - 0.0000000000000004454 83.0
TLS3_k127_6896715_4 PFAM MerR family regulatory protein K22491 - - 0.00000000000349 71.0
TLS3_k127_6905788_0 B12 binding domain K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 594.0
TLS3_k127_6905788_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000003176 246.0
TLS3_k127_6914166_0 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0 1253.0
TLS3_k127_6914166_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 464.0
TLS3_k127_6914166_2 Aminotransferase class-V - - - 0.000000000000000000001251 96.0
TLS3_k127_6923190_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 573.0
TLS3_k127_6923190_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000000001946 189.0
TLS3_k127_6923190_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000003813 125.0
TLS3_k127_6923190_3 serine-type aminopeptidase activity - - - 0.0000000000000000000006421 104.0
TLS3_k127_6948543_0 PFAM Peptidase family M1 K01256 - 3.4.11.2 4.297e-292 923.0
TLS3_k127_6948543_1 Castor and Pollux, part of voltage-gated ion channel - - - 1.126e-255 803.0
TLS3_k127_6948543_10 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000009327 230.0
TLS3_k127_6948543_11 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000008871 198.0
TLS3_k127_6948543_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000003582 201.0
TLS3_k127_6948543_13 Biotin-requiring enzyme K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000005278 187.0
TLS3_k127_6948543_14 - - - - 0.000000000000000000000000000000000000000001037 174.0
TLS3_k127_6948543_15 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000009887 158.0
TLS3_k127_6948543_16 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000003057 154.0
TLS3_k127_6948543_17 amine dehydrogenase activity - - - 0.0000000000000000000000000001167 128.0
TLS3_k127_6948543_18 B12 binding domain - - - 0.0000000000000000001032 91.0
TLS3_k127_6948543_19 FMN_bind - - - 0.0000000000003387 76.0
TLS3_k127_6948543_2 COGs COG1233 Phytoene dehydrogenase and related protein K09835 - 5.2.1.13 1.488e-212 674.0
TLS3_k127_6948543_20 Belongs to the peptidase S8 family - - - 0.0001047 56.0
TLS3_k127_6948543_3 domain protein - - - 8.633e-204 676.0
TLS3_k127_6948543_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 579.0
TLS3_k127_6948543_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 558.0
TLS3_k127_6948543_6 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 508.0
TLS3_k127_6948543_7 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 350.0
TLS3_k127_6948543_8 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002077 249.0
TLS3_k127_6948543_9 Thiol peroxidase K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
TLS3_k127_6956253_0 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 471.0
TLS3_k127_6956253_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001967 220.0
TLS3_k127_6976220_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 6.218e-242 756.0
TLS3_k127_6976220_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 319.0
TLS3_k127_6976220_2 PFAM Alanine dehydrogenase PNT, C-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000005464 241.0
TLS3_k127_6976220_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000001588 153.0
TLS3_k127_6982368_0 PFAM Glycosyl hydrolase family 3 N terminal domain - - - 4.036e-300 949.0
TLS3_k127_6982368_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 490.0
TLS3_k127_7005404_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 553.0
TLS3_k127_7005404_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 464.0
TLS3_k127_7005404_2 PFAM Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 433.0
TLS3_k127_7005404_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 374.0
TLS3_k127_7005404_4 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 351.0
TLS3_k127_7005404_5 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 315.0
TLS3_k127_7005404_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001684 263.0
TLS3_k127_7005404_7 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 237.0
TLS3_k127_7005885_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 349.0
TLS3_k127_7005885_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000003742 196.0
TLS3_k127_7005885_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000005147 199.0
TLS3_k127_7005885_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000356 165.0
TLS3_k127_7005885_4 methyltransferase - - - 0.00000000000000000006035 100.0
TLS3_k127_7005885_5 - - - - 0.0007204 44.0
TLS3_k127_7007954_0 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 295.0
TLS3_k127_7007954_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002293 267.0
TLS3_k127_7007954_2 heat shock protein binding K03686,K05801,K17867 - - 0.00000000000000000000000000000000000000000000001615 181.0
TLS3_k127_7007954_3 Phage envelope protein - - - 0.000000000000001798 76.0
TLS3_k127_7013525_0 Aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 1.659e-263 816.0
TLS3_k127_7013525_1 Belongs to the peptidase S1B family K01337 - 3.4.21.50 2.917e-195 630.0
TLS3_k127_7013525_10 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000003018 58.0
TLS3_k127_7013525_11 PKD domain - - - 0.000002083 59.0
TLS3_k127_7013525_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 358.0
TLS3_k127_7013525_3 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 287.0
TLS3_k127_7013525_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 273.0
TLS3_k127_7013525_6 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000005647 203.0
TLS3_k127_7013525_7 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.0000000000000000000000001553 109.0
TLS3_k127_7013525_9 VanZ like family - - - 0.0000000001067 67.0
TLS3_k127_7013855_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 494.0
TLS3_k127_7013855_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 288.0
TLS3_k127_7013855_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
TLS3_k127_7013855_3 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000004659 230.0
TLS3_k127_7013855_4 - - - - 0.000000000000000000000000000000000000000000000000000000008333 200.0
TLS3_k127_7013855_5 DNA mismatch repair protein - - - 0.0000000001637 68.0
TLS3_k127_7047359_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 532.0
TLS3_k127_7047359_1 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 466.0
TLS3_k127_7047359_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 414.0
TLS3_k127_7047359_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 272.0
TLS3_k127_7047359_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
TLS3_k127_7047359_5 GSCFA family - - - 0.00000000000000000000000000000000000000000000000000000000000000988 227.0
TLS3_k127_7047359_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000006693 184.0
TLS3_k127_7057433_0 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 1.802e-217 692.0
TLS3_k127_7057433_1 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
TLS3_k127_7057433_2 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 275.0
TLS3_k127_7057433_3 Endonuclease exonuclease phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000008929 217.0
TLS3_k127_7057433_4 - - - - 0.0000000000000000000000000000000000000000000172 169.0
TLS3_k127_7057433_5 WbqC-like protein - - - 0.00000000000000000000000000000000002474 143.0
TLS3_k127_7057433_6 ParB-like nuclease domain K03497 - - 0.000000005119 57.0
TLS3_k127_7063025_0 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 515.0
TLS3_k127_707201_0 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 483.0
TLS3_k127_707201_1 dihydroorotase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 445.0
TLS3_k127_707201_2 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 306.0
TLS3_k127_707201_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000003122 156.0
TLS3_k127_707201_4 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000004863 113.0
TLS3_k127_7081382_0 HsdM N-terminal domain K03427 - 2.1.1.72 0.0 1410.0
TLS3_k127_7081382_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.01e-272 850.0
TLS3_k127_7081382_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
TLS3_k127_7081382_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 293.0
TLS3_k127_7081382_5 - - - - 0.0000000000000000000000000000000000000000002841 171.0
TLS3_k127_71081_0 - - - - 0.0000000000000000000000000000000000000000001414 167.0
TLS3_k127_71081_1 Protein of unknown function (DUF1702) K21161 - - 0.000000000000000000000000000000002322 139.0
TLS3_k127_71081_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000001266 98.0
TLS3_k127_71081_3 metallopeptidase activity - - - 0.000000000001192 78.0
TLS3_k127_7112043_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 2.24e-214 673.0
TLS3_k127_7112043_1 Phosphoadenosine phosphosulfate reductase family K19170 - - 9.137e-201 632.0
TLS3_k127_7112043_10 RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000001016 190.0
TLS3_k127_7112043_11 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000391 158.0
TLS3_k127_7112043_12 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000001049 142.0
TLS3_k127_7112043_13 - - - - 0.000000000000000000000000000001715 125.0
TLS3_k127_7112043_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000003504 70.0
TLS3_k127_7112043_15 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000002601 61.0
TLS3_k127_7112043_16 MORN repeat variant - - - 0.000000001164 63.0
TLS3_k127_7112043_2 DNA sulfur modification protein DndD K19171 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 614.0
TLS3_k127_7112043_3 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 465.0
TLS3_k127_7112043_4 Bestrophin, RFP-TM, chloride channel K08994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
TLS3_k127_7112043_5 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 286.0
TLS3_k127_7112043_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002828 261.0
TLS3_k127_7112043_7 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000008146 235.0
TLS3_k127_7112043_8 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000001163 201.0
TLS3_k127_7112043_9 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000002383 189.0
TLS3_k127_7115063_0 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 576.0
TLS3_k127_7115063_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 511.0
TLS3_k127_7115063_2 Sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 284.0
TLS3_k127_7115063_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 - - 0.0000000000000000000000167 102.0
TLS3_k127_7115063_4 Hep Hag repeat protein K09942,K21449 - - 0.0000000000000000000003976 107.0
TLS3_k127_7115063_5 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000002234 52.0
TLS3_k127_7152488_0 receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 556.0
TLS3_k127_7152488_1 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 325.0
TLS3_k127_7152488_2 PFAM Response regulator receiver domain K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007014 263.0
TLS3_k127_7158780_0 Hsp70 protein K04043 - - 0.0 1081.0
TLS3_k127_7158780_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
TLS3_k127_7158780_2 Mechanosensitive ion channel K16052 - - 0.0005003 45.0
TLS3_k127_71657_0 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 580.0
TLS3_k127_71657_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 394.0
TLS3_k127_71657_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 287.0
TLS3_k127_71657_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000546 150.0
TLS3_k127_71657_4 - - - - 0.000000000000000000000000000001479 125.0
TLS3_k127_7174293_0 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 479.0
TLS3_k127_7174293_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 445.0
TLS3_k127_7174293_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
TLS3_k127_7174293_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000002011 176.0
TLS3_k127_7174293_4 transport - - - 0.0000000000000000000000000000000000000000000003633 177.0
TLS3_k127_7174293_5 Esterase PHB depolymerase - - - 0.00003771 48.0
TLS3_k127_7216453_0 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000000000000000005628 212.0
TLS3_k127_7216453_1 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000003812 160.0
TLS3_k127_7216453_2 CotH kinase protein - - - 0.00000002771 59.0
TLS3_k127_7220363_0 TIGRFAM oligoendopeptidase, M3 family K08602 - - 1.38e-220 697.0
TLS3_k127_7220363_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 374.0
TLS3_k127_7220363_2 - - - - 0.0000000000000000000000000000000000000000000000000245 184.0
TLS3_k127_7222238_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000368 257.0
TLS3_k127_7222238_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000009552 226.0
TLS3_k127_7222238_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000002465 126.0
TLS3_k127_7222238_3 Domain of unknown function (DUF4476) - - - 0.000000009039 64.0
TLS3_k127_7241212_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 567.0
TLS3_k127_7241212_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 375.0
TLS3_k127_7241212_2 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000008888 181.0
TLS3_k127_7260082_0 CarboxypepD_reg-like domain - - - 0.0 1100.0
TLS3_k127_7260082_1 RQC K03654 - 3.6.4.12 1.184e-265 824.0
TLS3_k127_7260082_2 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 451.0
TLS3_k127_7260082_3 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 404.0
TLS3_k127_7260082_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 344.0
TLS3_k127_7260082_5 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.0000000000000000000000000000000000000000000000004673 183.0
TLS3_k127_7263464_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1126.0
TLS3_k127_7263464_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.263e-230 720.0
TLS3_k127_7263464_10 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003029 279.0
TLS3_k127_7263464_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 279.0
TLS3_k127_7263464_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003407 242.0
TLS3_k127_7263464_13 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001228 226.0
TLS3_k127_7263464_14 - - - - 0.000000000000000000000000000000000000000000000001741 179.0
TLS3_k127_7263464_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000007131 175.0
TLS3_k127_7263464_16 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000000000000000000000000000023 145.0
TLS3_k127_7263464_17 - - - - 0.0000000000000000000000006543 114.0
TLS3_k127_7263464_18 YceI-like domain - - - 0.00000000000000000000004255 105.0
TLS3_k127_7263464_19 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.000000000000000000006087 102.0
TLS3_k127_7263464_2 PFAM FG-GAP repeat - - - 1.472e-226 724.0
TLS3_k127_7263464_20 - - - - 0.0000000000000000000378 94.0
TLS3_k127_7263464_21 Domain of unknown function (DUF4837) - - - 0.000000000000000003651 96.0
TLS3_k127_7263464_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000156 84.0
TLS3_k127_7263464_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000009145 76.0
TLS3_k127_7263464_24 Helix-turn-helix domain - - - 0.0000000002076 72.0
TLS3_k127_7263464_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000001516 66.0
TLS3_k127_7263464_26 - - - - 0.0002561 51.0
TLS3_k127_7263464_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.103e-204 646.0
TLS3_k127_7263464_4 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 577.0
TLS3_k127_7263464_5 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 561.0
TLS3_k127_7263464_6 membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 393.0
TLS3_k127_7263464_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 379.0
TLS3_k127_7263464_8 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 338.0
TLS3_k127_7263464_9 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 308.0
TLS3_k127_7278250_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003404 232.0
TLS3_k127_7278250_1 peptidase - - - 0.000000000000000000000000000000000000000000008477 177.0
TLS3_k127_7278250_2 - - - - 0.00000000000000000000007324 106.0
TLS3_k127_7279084_0 WD-40 repeat - - - 0.000000001595 69.0
TLS3_k127_7279084_1 - - - - 0.000009006 55.0
TLS3_k127_728053_0 ABC-type multidrug transport system ATPase and permease K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 617.0
TLS3_k127_728053_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 487.0
TLS3_k127_728053_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
TLS3_k127_728053_3 Protein of unknown function (DUF3276) - - - 0.000000000000000000000000000003885 122.0
TLS3_k127_7287610_0 Chorismate mutase type II K04516 - 5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 485.0
TLS3_k127_7287610_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 375.0
TLS3_k127_7287610_2 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 322.0
TLS3_k127_7287610_3 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004366 246.0
TLS3_k127_7287610_4 TIGRFAM Gliding motility-associated lipoprotein GldK - - - 0.000000000000000000000000007163 117.0
TLS3_k127_7287610_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000003342 93.0
TLS3_k127_7293018_0 - - - - 0.000000000000000000000000000000000000000000001555 173.0
TLS3_k127_7293018_1 ADP-glyceromanno-heptose 6-epimerase activity K01784,K01955,K02377 - 1.1.1.271,5.1.3.2,6.3.5.5 0.0000000000000000000000000000000000003238 147.0
TLS3_k127_7293018_2 Protein of unknown function, DUF393 - - - 0.00000000000000000000000005617 120.0
TLS3_k127_7308941_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000000000000000001454 184.0
TLS3_k127_7308941_1 His Kinase A (phosphoacceptor) domain - - - 0.00001089 57.0
TLS3_k127_732851_0 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005447 275.0
TLS3_k127_7358180_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.181e-293 905.0
TLS3_k127_7358180_1 SprB repeat - - - 3.617e-240 802.0
TLS3_k127_7358180_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000001536 142.0
TLS3_k127_7358180_11 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000001018 106.0
TLS3_k127_7358180_12 oxidoreductase activity - - - 0.00000000000000001583 99.0
TLS3_k127_7358180_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 8.374e-221 692.0
TLS3_k127_7358180_3 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 600.0
TLS3_k127_7358180_4 ATPase (AAA superfamily) K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 477.0
TLS3_k127_7358180_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002437 277.0
TLS3_k127_7358180_6 Leucine-rich repeat (LRR) protein - - - 0.000000000000000000000000000000000000000000000000000000000001494 241.0
TLS3_k127_7358180_7 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000003097 163.0
TLS3_k127_7358180_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000001769 157.0
TLS3_k127_7358180_9 - - - - 0.000000000000000000000000000000000000000273 164.0
TLS3_k127_7368211_0 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 377.0
TLS3_k127_7368211_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 333.0
TLS3_k127_7368211_2 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 265.0
TLS3_k127_7368211_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000195 245.0
TLS3_k127_7368211_4 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000001886 233.0
TLS3_k127_7368211_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000001748 144.0
TLS3_k127_7383688_0 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000004303 252.0
TLS3_k127_7383688_1 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000005227 242.0
TLS3_k127_7410722_0 PhoU domain K03324 - - 7.157e-222 709.0
TLS3_k127_7410722_1 PFAM Response regulator receiver domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 305.0
TLS3_k127_7410722_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000001266 230.0
TLS3_k127_7410722_3 TonB dependent receptor - - - 0.00000000000000000000000007145 111.0
TLS3_k127_746897_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 8.114e-257 801.0
TLS3_k127_746897_1 GlcNAc-PI de-N-acetylase - - - 1.29e-225 716.0
TLS3_k127_746897_2 KAP family P-loop domain - - - 0.0000000000000000000000000000000000000000005388 179.0
TLS3_k127_7492660_0 Vitamin B12 dependent methionine synthase, activation domain K00548 - 2.1.1.13 0.0 1233.0
TLS3_k127_7492660_1 5-methyltetrahydrofolate-dependent methyltransferase activity K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 538.0
TLS3_k127_7492660_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 456.0
TLS3_k127_7492660_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000005832 178.0
TLS3_k127_7492660_4 membrane - - - 0.0000000000000000000000000405 112.0
TLS3_k127_7492660_6 - - - - 0.00005869 48.0
TLS3_k127_7504622_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 444.0
TLS3_k127_7504622_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000002103 91.0
TLS3_k127_7504622_2 SPTR CHU large protein - - - 0.00000000008102 63.0
TLS3_k127_7508059_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 532.0
TLS3_k127_7508059_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 405.0
TLS3_k127_7508059_2 Endonuclease/Exonuclease/phosphatase family K01117 - 3.1.4.12 0.000000001199 68.0
TLS3_k127_7511895_0 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 521.0
TLS3_k127_7511895_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
TLS3_k127_7511895_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000004517 188.0
TLS3_k127_7512829_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 8.314e-285 891.0
TLS3_k127_7512829_1 Response regulator of the LytR AlgR family - - - 0.0000000000000000000000000000000000000000000007402 167.0
TLS3_k127_7512829_2 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000007001 81.0
TLS3_k127_7528851_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 308.0
TLS3_k127_7528851_1 Domain of unknown function (DUF4494) - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
TLS3_k127_7528851_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
TLS3_k127_7528851_3 Transglycosylase associated protein - - - 0.0000000000004013 72.0
TLS3_k127_7528851_4 PFAM Peptidase M16 inactive domain - - - 0.0000000001368 63.0
TLS3_k127_7534805_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 6.985e-251 777.0
TLS3_k127_7534805_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 6.572e-194 609.0
TLS3_k127_7534805_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 485.0
TLS3_k127_7534805_3 ubiE/COQ5 methyltransferase family K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 343.0
TLS3_k127_7534805_4 CAAX amino terminal protease family K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008864 249.0
TLS3_k127_7534805_5 Wd-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002712 228.0
TLS3_k127_7534805_6 PFAM AhpC TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000003154 216.0
TLS3_k127_7534805_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000003169 194.0
TLS3_k127_7534805_8 WG containing repeat - - - 0.0000000004074 74.0
TLS3_k127_7538599_0 ABC transporter, transmembrane region K11085 - - 1.287e-264 826.0
TLS3_k127_7538599_1 FAD-NAD(P)-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 360.0
TLS3_k127_7538599_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000256 239.0
TLS3_k127_7538599_3 SPTR Cell surface protein K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000001203 235.0
TLS3_k127_7538599_4 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000002057 123.0
TLS3_k127_7538599_5 odorant binding - GO:0003008,GO:0003674,GO:0004857,GO:0004866,GO:0004869,GO:0005102,GO:0005488,GO:0005515,GO:0005549,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007635,GO:0008150,GO:0008152,GO:0008270,GO:0009892,GO:0010466,GO:0010605,GO:0010876,GO:0010951,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0019222,GO:0019538,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031404,GO:0032268,GO:0032269,GO:0032501,GO:0033036,GO:0042221,GO:0042802,GO:0042803,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043621,GO:0044092,GO:0044238,GO:0044421,GO:0045861,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071702,GO:0071704,GO:0080090,GO:0098772,GO:1901564 - 0.0000000000000000000000004422 121.0
TLS3_k127_7538599_6 regulation of response to stimulus - - - 0.000000000005926 78.0
TLS3_k127_7552777_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
TLS3_k127_7552777_1 Transcriptional regulator K13572 - - 0.000000000000000007265 86.0
TLS3_k127_7552777_2 - - - - 0.00000000007797 72.0
TLS3_k127_7552777_3 peptidase S41 - - - 0.00000147 61.0
TLS3_k127_7572226_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1253.0
TLS3_k127_7572226_1 Lamin Tail Domain - - - 2.959e-282 891.0
TLS3_k127_7572226_10 LETM1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 367.0
TLS3_k127_7572226_11 PFAM Peptidase C1-like family K01372 - 3.4.22.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 351.0
TLS3_k127_7572226_12 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 358.0
TLS3_k127_7572226_13 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 304.0
TLS3_k127_7572226_14 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001355 278.0
TLS3_k127_7572226_15 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
TLS3_k127_7572226_16 Suppressor of fused protein (SUFU) - - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
TLS3_k127_7572226_17 - - - - 0.0000000000000000000000000000000000000000000002477 171.0
TLS3_k127_7572226_18 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000004253 145.0
TLS3_k127_7572226_19 pectinesterase activity K10297,K15923,K18197 - 3.2.1.51,4.2.2.23 0.0000000000000000000000000001325 133.0
TLS3_k127_7572226_2 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 2.128e-215 677.0
TLS3_k127_7572226_20 - - - - 0.000000000000000000000000003062 123.0
TLS3_k127_7572226_21 - - - - 0.00000000000000000000000001043 123.0
TLS3_k127_7572226_22 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000001574 111.0
TLS3_k127_7572226_23 Belongs to the ompA family - - - 0.000000000000000000003559 104.0
TLS3_k127_7572226_24 Protein of unknown function (DUF2892) - - - 0.00000000000000138 78.0
TLS3_k127_7572226_25 - - - - 0.00000000001421 71.0
TLS3_k127_7572226_3 Aminotransferase class-III K01845 - 5.4.3.8 2.95e-212 668.0
TLS3_k127_7572226_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 8.569e-203 638.0
TLS3_k127_7572226_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 541.0
TLS3_k127_7572226_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 514.0
TLS3_k127_7572226_7 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 516.0
TLS3_k127_7572226_8 Class I and II K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 470.0
TLS3_k127_7572226_9 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 387.0
TLS3_k127_7588403_0 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000000731 166.0
TLS3_k127_7588403_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000003301 98.0
TLS3_k127_7588403_2 domain, Protein K01347,K03561,K12287 - 3.4.21.72 0.000000000000000000006493 106.0
TLS3_k127_7588403_3 regulation of response to stimulus - - - 0.0000000000203 72.0
TLS3_k127_7611140_0 metallopeptidase activity K01337,K13735,K15125 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000002751 267.0
TLS3_k127_7611140_1 - - - - 0.0000000000000000000000000000001949 135.0
TLS3_k127_7636705_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 599.0
TLS3_k127_7636705_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 481.0
TLS3_k127_7636705_2 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 412.0
TLS3_k127_7636705_3 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000502 248.0
TLS3_k127_7636705_4 Na dependent nucleoside transporter K03317 - - 0.00000000000004814 81.0
TLS3_k127_7636705_5 - - - - 0.000004227 56.0
TLS3_k127_7649803_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004022 270.0
TLS3_k127_7649803_1 Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001261 249.0
TLS3_k127_7649803_2 dioxygenase activity K03183,K04040 - 2.1.1.163,2.1.1.201,2.5.1.133,2.5.1.62 0.00000000000000000000000004923 121.0
TLS3_k127_767060_0 PFAM Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 353.0
TLS3_k127_767060_1 PFAM Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 303.0
TLS3_k127_767060_2 Spore coat protein CotH K01337,K04771 - 3.4.21.107,3.4.21.50 0.00000000000000000000000000000000005462 148.0
TLS3_k127_767060_3 - - - - 0.00000000000000000004218 91.0
TLS3_k127_767060_4 Ankyrin repeat - - - 0.0000000000000000007229 98.0
TLS3_k127_767060_5 metallopeptidase activity - - - 0.0000000000002612 81.0
TLS3_k127_7671832_0 Peptidoglycan-binding domain 1 protein - - - 3.72e-281 914.0
TLS3_k127_7676232_0 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 589.0
TLS3_k127_7676232_1 Bacterial low temperature requirement A protein (LtrA) K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 321.0
TLS3_k127_7676232_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009914 270.0
TLS3_k127_7676232_3 COG4206 Outer membrane cobalamin receptor protein K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006106 266.0
TLS3_k127_7676232_4 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
TLS3_k127_7696870_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979,K19714 - 1.1.3.48,2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 317.0
TLS3_k127_7696870_1 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001555 291.0
TLS3_k127_7696870_2 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001583 241.0
TLS3_k127_7696870_3 PFAM Peptidase C1-like family K01372 - 3.4.22.40 0.000000000000000000000000000000000000000000000001409 177.0
TLS3_k127_7697484_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000007236 209.0
TLS3_k127_7697484_1 C-terminal domain of CHU protein family - - - 0.00000000000002719 87.0
TLS3_k127_7707034_0 PFAM GHMP kinases N terminal domain K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 493.0
TLS3_k127_7707034_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 396.0
TLS3_k127_7707034_2 diphosphomevalonate decarboxylase K01597 - 4.1.1.33 0.000000000000000000005991 92.0
TLS3_k127_7727127_0 Nucleoside recognition K06373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 497.0
TLS3_k127_7727127_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 391.0
TLS3_k127_7727127_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 389.0
TLS3_k127_7727127_3 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003587 280.0
TLS3_k127_7727127_4 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 258.0
TLS3_k127_7727127_5 Eukaryotic integral membrane protein (DUF1751) K09650 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000001099 218.0
TLS3_k127_7727127_6 COG1807 4-amino-4-deoxy-L-arabinose transferase and related - - - 0.0000000000000000000000000000000000000000000000000000000002093 206.0
TLS3_k127_7727127_7 - - - - 0.0000000000000000000000000000000000000000000001864 172.0
TLS3_k127_7727127_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000001811 144.0
TLS3_k127_7738417_0 Belongs to the UPF0753 family K09822 - - 5.811e-285 898.0
TLS3_k127_7738417_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.874e-228 722.0
TLS3_k127_7738417_10 PFAM Peptidase C14, caspase catalytic - - - 0.000000000000000000000000000000000000000001415 178.0
TLS3_k127_7738417_11 Astacin (Peptidase family M12A) - - - 0.00000000000000000000000000000002637 145.0
TLS3_k127_7738417_12 - - - - 0.0000000000000000000000000000006335 134.0
TLS3_k127_7738417_14 Pkd domain containing protein - - - 0.000000000000005339 89.0
TLS3_k127_7738417_15 Histidine kinase - - - 0.00000000000008382 76.0
TLS3_k127_7738417_16 Protein conserved in bacteria - - - 0.0000000000002439 82.0
TLS3_k127_7738417_17 COGs COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000003254 69.0
TLS3_k127_7738417_19 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.00000005173 64.0
TLS3_k127_7738417_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 310.0
TLS3_k127_7738417_20 UbiA prenyltransferase K09833 GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 2.5.1.115,2.5.1.116 0.0000001368 63.0
TLS3_k127_7738417_21 - - - - 0.0007884 49.0
TLS3_k127_7738417_3 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008997 250.0
TLS3_k127_7738417_4 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008989 267.0
TLS3_k127_7738417_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000001908 207.0
TLS3_k127_7738417_6 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000000000009941 200.0
TLS3_k127_7738417_7 Phosphoribosyl transferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000007267 199.0
TLS3_k127_7738417_8 STAS domain K03321 - - 0.000000000000000000000000000000000000000000000004342 189.0
TLS3_k127_7738417_9 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000001034 179.0
TLS3_k127_7738639_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.684e-250 779.0
TLS3_k127_7738639_1 PFAM Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 579.0
TLS3_k127_7738639_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
TLS3_k127_7738639_12 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000002969 190.0
TLS3_k127_7738639_13 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000005683 110.0
TLS3_k127_7738639_14 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000004102 105.0
TLS3_k127_7738639_15 Recombinase - - - 0.000000000888 60.0
TLS3_k127_7738639_2 Iron-containing alcohol dehydrogenase K08325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008177 495.0
TLS3_k127_7738639_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 462.0
TLS3_k127_7738639_4 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 391.0
TLS3_k127_7738639_5 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 376.0
TLS3_k127_7738639_6 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 316.0
TLS3_k127_7738639_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 306.0
TLS3_k127_7738639_8 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 308.0
TLS3_k127_7738639_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 290.0
TLS3_k127_7741347_0 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 399.0
TLS3_k127_7741347_1 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 315.0
TLS3_k127_7743028_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 602.0
TLS3_k127_7743028_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
TLS3_k127_7743370_0 ubiE/COQ5 methyltransferase family K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000403 214.0
TLS3_k127_7743370_1 Mg-protoporphyrin IX monomethyl ester oxidative cyclase 66kD subunit K04034 - 1.21.98.3 0.000000000000000000000000000000000000002267 150.0
TLS3_k127_7743370_2 - - - - 0.00000000000000000000000000000000000009066 144.0
TLS3_k127_7743370_4 Domain of unknown function (DUF1735) - - - 0.0000000000000000000001767 112.0
TLS3_k127_7757642_0 Arginyl tRNA synthetase N terminal domain K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.315e-274 857.0
TLS3_k127_7757642_1 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 425.0
TLS3_k127_7757642_2 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 395.0
TLS3_k127_7757642_3 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
TLS3_k127_7757642_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
TLS3_k127_7757642_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000006195 218.0
TLS3_k127_7757642_6 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
TLS3_k127_7760388_0 Carboxypeptidase regulatory-like domain - - - 0.0 1665.0
TLS3_k127_7760388_1 - - - - 0.0 1542.0
TLS3_k127_7760388_2 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 499.0
TLS3_k127_7760388_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000001532 236.0
TLS3_k127_7760388_4 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000008787 215.0
TLS3_k127_7760388_5 HIT domain K02503 - - 0.00000000000000000000000000000000000000000000000000002145 191.0
TLS3_k127_7760388_6 Protein of unknown function (DUF1624) - - - 0.000686 44.0
TLS3_k127_777791_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 544.0
TLS3_k127_777791_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 529.0
TLS3_k127_777791_2 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000004331 200.0
TLS3_k127_777791_3 - - - - 0.000000005667 58.0
TLS3_k127_7786656_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 1.261e-230 722.0
TLS3_k127_7786656_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 541.0
TLS3_k127_7786656_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000009483 161.0
TLS3_k127_7786656_3 - - - - 0.000000000000000000000003515 107.0
TLS3_k127_7786656_4 Novel toxin 21 - - - 0.0000000000000005399 82.0
TLS3_k127_7805656_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 508.0
TLS3_k127_7805656_1 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 341.0
TLS3_k127_7805656_2 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
TLS3_k127_7805656_3 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000003516 250.0
TLS3_k127_7805656_4 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000546 231.0
TLS3_k127_7805656_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000001849 126.0
TLS3_k127_7805656_6 tetratricopeptide repeat - - - 0.0000000000009393 77.0
TLS3_k127_7809381_0 Protein of unknown function (DUF2723) - - - 0.0 1325.0
TLS3_k127_7809381_1 - - - - 1.972e-232 722.0
TLS3_k127_7809381_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000199 116.0
TLS3_k127_7809381_3 - - - - 0.000000000000000009392 83.0
TLS3_k127_7809381_4 - - - - 0.00000000000193 77.0
TLS3_k127_7820510_0 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 1.548e-297 919.0
TLS3_k127_7820510_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001092 222.0
TLS3_k127_7820510_2 signal transduction protein with a C-terminal ATPase domain - - - 0.00005419 53.0
TLS3_k127_7841437_0 - - - - 0.0 1903.0
TLS3_k127_7841437_1 oxidoreductase activity - - - 0.0 1593.0
TLS3_k127_7841437_2 Phage integrase SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000638 218.0
TLS3_k127_7848517_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 589.0
TLS3_k127_7848517_1 Helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 324.0
TLS3_k127_7848517_2 TIGRFAM branched-chain amino acid aminotransferase, group II K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
TLS3_k127_7853268_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 6.497e-275 859.0
TLS3_k127_7853268_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 415.0
TLS3_k127_7853268_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase CLD K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 394.0
TLS3_k127_7853268_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
TLS3_k127_7853268_4 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
TLS3_k127_7853268_5 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
TLS3_k127_7853268_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 264.0
TLS3_k127_7853268_7 repeat protein - - - 0.0003987 44.0
TLS3_k127_7879541_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 421.0
TLS3_k127_7887948_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 4.261e-296 913.0
TLS3_k127_7887948_1 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 341.0
TLS3_k127_7899315_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 512.0
TLS3_k127_7899315_1 alpha beta K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000007247 246.0
TLS3_k127_7899315_2 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000312 142.0
TLS3_k127_7899315_3 Excinuclease ABC subunit B - - - 0.0000000000000000000000000000002586 138.0
TLS3_k127_7930152_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.709e-281 870.0
TLS3_k127_7930152_1 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 585.0
TLS3_k127_7930152_10 Rieske (2Fe-2S) domain K05710 - - 0.000000000002581 72.0
TLS3_k127_7930152_2 Pfam Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 433.0
TLS3_k127_7930152_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 418.0
TLS3_k127_7930152_4 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 369.0
TLS3_k127_7930152_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 312.0
TLS3_k127_7930152_6 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
TLS3_k127_7930152_7 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000009106 183.0
TLS3_k127_7930152_8 HutD - - - 0.000000000000000000000000000000000000001138 154.0
TLS3_k127_7930152_9 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000571 97.0
TLS3_k127_7933810_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1109.0
TLS3_k127_7933810_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 368.0
TLS3_k127_7933810_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007254 275.0
TLS3_k127_7933810_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009767 205.0
TLS3_k127_7933810_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000003047 135.0
TLS3_k127_7933810_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000006934 110.0
TLS3_k127_7933810_6 - - - - 0.000000000000000000000003807 107.0
TLS3_k127_7936545_0 N-6 DNA Methylase - - - 0.0 1083.0
TLS3_k127_7936545_1 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 535.0
TLS3_k127_7936545_11 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000111 56.0
TLS3_k127_7936545_12 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0002416 44.0
TLS3_k127_7936545_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 426.0
TLS3_k127_7936545_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 394.0
TLS3_k127_7936545_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 335.0
TLS3_k127_7936545_5 RHS repeat-associated core domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 302.0
TLS3_k127_7936545_6 Type I restriction modification DNA specificity domain - - - 0.000000000000000000000000000000000000000000000000000000001792 226.0
TLS3_k127_7936545_7 Pkd domain containing protein - - - 0.000000000000000000000000000000000004856 154.0
TLS3_k127_7936545_8 - - - - 0.0000000000000000157 85.0
TLS3_k127_7936545_9 ABC transporter transmembrane region K06147 - - 0.000000004378 57.0
TLS3_k127_7938204_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.245e-268 830.0
TLS3_k127_7938204_1 SPTR Conserved repeat domain protein - - - 0.00000000000000000000000000000000000000002691 167.0
TLS3_k127_7938204_2 regulator of chromosome condensation, RCC1 - - - 0.000000000000002024 88.0
TLS3_k127_7941787_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 1.291e-217 681.0
TLS3_k127_7941787_1 CTP synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 296.0
TLS3_k127_7941787_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000007841 151.0
TLS3_k127_7941787_3 - - - - 0.000000000000000000000000000000000001595 148.0
TLS3_k127_7941787_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000368 102.0
TLS3_k127_7941787_5 LytTr DNA-binding domain K02477 - - 0.000000000001025 70.0
TLS3_k127_7945013_0 C-terminal domain of CHU protein family - - - 4.382e-268 852.0
TLS3_k127_7945013_1 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
TLS3_k127_7945013_2 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 334.0
TLS3_k127_7945013_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002309 291.0
TLS3_k127_7945013_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000005663 193.0
TLS3_k127_7945013_5 PFAM NAD-dependent epimerase dehydratase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000001167 158.0
TLS3_k127_7945013_6 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000000000000000000000000000121 144.0
TLS3_k127_7945013_7 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000008282 129.0
TLS3_k127_7945013_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000004441 62.0
TLS3_k127_7949253_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 443.0
TLS3_k127_7949253_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008481 253.0
TLS3_k127_7949253_2 PspC domain K03973 - - 0.000000000000000000000000000000000000000000000001972 192.0
TLS3_k127_7949253_3 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000153 169.0
TLS3_k127_7949253_4 Transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000000002145 163.0
TLS3_k127_7949253_5 Low molecular weight phosphotyrosine protein phosphatase - - - 0.00000000000000000000000000009856 119.0
TLS3_k127_7960125_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 554.0
TLS3_k127_7960125_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 464.0
TLS3_k127_7960125_10 response to abiotic stimulus - - - 0.0000004322 59.0
TLS3_k127_7960125_2 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 424.0
TLS3_k127_7960125_3 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 316.0
TLS3_k127_7960125_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 292.0
TLS3_k127_7960125_5 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005507 299.0
TLS3_k127_7960125_6 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000007292 218.0
TLS3_k127_7960125_7 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000001082 218.0
TLS3_k127_7960125_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000151 199.0
TLS3_k127_7960125_9 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000001613 183.0
TLS3_k127_7972903_0 Peptidase family C25 - - - 0.0 1447.0
TLS3_k127_7972903_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0 1212.0
TLS3_k127_7972903_10 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 329.0
TLS3_k127_7972903_11 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
TLS3_k127_7972903_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 282.0
TLS3_k127_7972903_13 - - - - 0.00000000000000000000000000000000000000000000003148 175.0
TLS3_k127_7972903_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000007892 173.0
TLS3_k127_7972903_15 response to heat K03808 - - 0.000000000000000000000000000000000000000003446 170.0
TLS3_k127_7972903_16 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000001029 135.0
TLS3_k127_7972903_17 Domain of unknown function (DUF4920) - - - 0.00000000000000000000000252 109.0
TLS3_k127_7972903_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1211.0
TLS3_k127_7972903_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.975e-302 935.0
TLS3_k127_7972903_4 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278,K18574 - 3.4.14.12,3.4.14.5 7.073e-286 893.0
TLS3_k127_7972903_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.325e-208 652.0
TLS3_k127_7972903_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 541.0
TLS3_k127_7972903_7 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
TLS3_k127_7972903_8 PFAM UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 420.0
TLS3_k127_7972903_9 DbpA RNA binding domain K05591 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 387.0
TLS3_k127_7978373_0 Squalene epoxidase K00511 - 1.14.14.17 3.589e-211 662.0
TLS3_k127_7978373_1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 588.0
TLS3_k127_7978373_2 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 562.0
TLS3_k127_7978373_3 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008677 277.0
TLS3_k127_7978373_4 YHYH protein - - - 0.000000000000000000000000000000000000000000007284 167.0
TLS3_k127_7992505_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.561e-298 921.0
TLS3_k127_7992505_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.13e-204 653.0
TLS3_k127_7992505_2 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000001369 209.0
TLS3_k127_7992505_3 PFAM Kelch motif - - - 0.0000000002999 63.0
TLS3_k127_7992505_4 - - - - 0.00002288 53.0
TLS3_k127_8015789_0 phosphatase K07004 - - 0.000004227 56.0
TLS3_k127_8015789_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.0001459 51.0
TLS3_k127_8034413_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 519.0
TLS3_k127_8034413_1 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
TLS3_k127_8034413_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 289.0
TLS3_k127_8057207_0 AcrB/AcrD/AcrF family - - - 0.0 1131.0
TLS3_k127_8057207_1 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000000000006252 113.0
TLS3_k127_8066180_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 1.064e-300 929.0
TLS3_k127_8066180_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 437.0
TLS3_k127_8066180_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 297.0
TLS3_k127_8066180_4 phosphoserine phosphatase activity - - - 0.00000001143 59.0
TLS3_k127_8086751_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000503 210.0
TLS3_k127_8086751_1 Peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.00000000000000000000000000000000002089 141.0
TLS3_k127_8086751_2 - - - - 0.000000000000000000000000000000004211 141.0
TLS3_k127_8086751_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000004346 115.0
TLS3_k127_8113755_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001465 297.0
TLS3_k127_8121907_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 406.0
TLS3_k127_8121907_1 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000001064 188.0
TLS3_k127_8121907_2 Protein of unknown function (DUF3634) - - - 0.00000002488 61.0
TLS3_k127_8127602_0 PFAM TonB-dependent Receptor Plug Domain - - - 1.071e-310 969.0
TLS3_k127_8127602_1 Domain of unknown function (DUF4249) - - - 0.000000000000000000000002146 109.0
TLS3_k127_8128458_0 TonB dependent receptor K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000001584 263.0
TLS3_k127_815194_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.504e-273 857.0
TLS3_k127_815194_1 AMP-binding enzyme K01897 - 6.2.1.3 3.4e-253 793.0
TLS3_k127_815194_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 591.0
TLS3_k127_815194_3 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 439.0
TLS3_k127_815194_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001181 187.0
TLS3_k127_8157355_0 - - - - 9.973e-243 760.0
TLS3_k127_8157355_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 353.0
TLS3_k127_8157355_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 348.0
TLS3_k127_8292994_0 ATPase domain of DNA mismatch repair MUTS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 533.0
TLS3_k127_8292994_1 COG5337 Spore coat assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 453.0
TLS3_k127_8292994_2 Protein of unknown function (DUF2490) - - - 0.0000000000000000000002882 101.0
TLS3_k127_8316848_0 - - - - 0.0 1660.0
TLS3_k127_8316848_1 nuclear chromosome segregation - - - 8.959e-265 895.0
TLS3_k127_8316848_2 DoxX family - - - 9.263e-216 687.0
TLS3_k127_8316848_3 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 313.0
TLS3_k127_8316848_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
TLS3_k127_8316848_5 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
TLS3_k127_8316848_6 Domain of Unknown Function (DUF1599) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
TLS3_k127_8316848_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
TLS3_k127_8316848_8 PFAM ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000000000000007694 140.0
TLS3_k127_8316848_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000216 66.0
TLS3_k127_831926_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 550.0
TLS3_k127_831926_1 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 499.0
TLS3_k127_831926_2 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 341.0
TLS3_k127_831926_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 316.0
TLS3_k127_831926_4 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000001752 178.0
TLS3_k127_831926_5 - - - - 0.00000000005894 65.0
TLS3_k127_831926_6 YtxH-like protein - - - 0.00000000152 60.0
TLS3_k127_831926_7 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00005329 50.0
TLS3_k127_8329890_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 329.0
TLS3_k127_8329890_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000004473 196.0
TLS3_k127_8335032_0 Sulfatase K01138 - - 2.635e-209 670.0
TLS3_k127_8335032_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 451.0
TLS3_k127_8335032_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
TLS3_k127_8335032_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 338.0
TLS3_k127_8335032_4 zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 311.0
TLS3_k127_8335032_5 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000000000000000000000000000000000002355 162.0
TLS3_k127_8335032_6 - - - - 0.00000000000000000000000000004437 126.0
TLS3_k127_8335032_7 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000001141 121.0
TLS3_k127_8350847_0 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 465.0
TLS3_k127_8350847_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 392.0
TLS3_k127_8350847_2 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 328.0
TLS3_k127_8350847_3 - - - - 0.00000000000003804 77.0
TLS3_k127_8377084_0 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 6.481e-307 955.0
TLS3_k127_8377084_1 Glycosyl hydrolase family 92 - - - 5.224e-286 910.0
TLS3_k127_8377084_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000001144 230.0
TLS3_k127_8377084_11 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002886 216.0
TLS3_k127_8377084_12 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000000000000002866 208.0
TLS3_k127_8377084_13 Uncharacterized ACR, COG1678 K07735 - - 0.000000000000000000000000000000000000000000000000004495 187.0
TLS3_k127_8377084_14 4Fe-4S dicluster domain - - - 0.00000000000000000000000000005261 118.0
TLS3_k127_8377084_15 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000006341 123.0
TLS3_k127_8377084_16 - - - - 0.0000002775 53.0
TLS3_k127_8377084_2 Organic solvent tolerance protein OstA - - - 1.18e-240 770.0
TLS3_k127_8377084_3 ATPase family associated with various cellular activities (AAA) K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 614.0
TLS3_k127_8377084_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 480.0
TLS3_k127_8377084_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 416.0
TLS3_k127_8377084_6 Glucokinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 391.0
TLS3_k127_8377084_7 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 364.0
TLS3_k127_8377084_8 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 336.0
TLS3_k127_8377084_9 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002011 251.0
TLS3_k127_8402286_0 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
TLS3_k127_8402286_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 376.0
TLS3_k127_8402286_2 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005646 283.0
TLS3_k127_8402286_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000001056 169.0
TLS3_k127_8402286_4 PFAM Penicillinase repressor - - - 0.000000000000000000000000000000000000003109 149.0
TLS3_k127_8402286_5 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000004029 141.0
TLS3_k127_8402286_6 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000007099 93.0
TLS3_k127_8402286_7 - - - - 0.00000000000000000002779 93.0
TLS3_k127_8402286_9 - - - - 0.00000000003332 68.0
TLS3_k127_8453014_0 Sortilin, neurotensin receptor 3, - - - 0.0 1444.0
TLS3_k127_8453014_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.765e-237 738.0
TLS3_k127_8453014_10 SMART von Willebrand factor, type A K07114 - - 0.00000000000000000000000000004411 136.0
TLS3_k127_8453014_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000005496 121.0
TLS3_k127_8453014_12 RHS Repeat - - - 0.0000000000000000982 95.0
TLS3_k127_8453014_13 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000006814 89.0
TLS3_k127_8453014_14 40-residue YVTN family beta-propeller repeat - - - 0.000000001967 70.0
TLS3_k127_8453014_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 431.0
TLS3_k127_8453014_4 - K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 429.0
TLS3_k127_8453014_5 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 368.0
TLS3_k127_8453014_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
TLS3_k127_8453014_7 SPTR Cell surface protein K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000002538 215.0
TLS3_k127_8453014_8 SprB repeat - - - 0.0000000000000000000000000000001622 143.0
TLS3_k127_8453014_9 Heavy-metal-associated domain - - - 0.000000000000000000000000000005215 124.0
TLS3_k127_845719_0 PFAM Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 604.0
TLS3_k127_845719_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 245.0
TLS3_k127_845719_2 GCN5 family acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002173 200.0
TLS3_k127_8463818_0 MgtE intracellular N domain K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 395.0
TLS3_k127_8463818_1 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 393.0
TLS3_k127_8463818_2 S-adenosylmethionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 386.0
TLS3_k127_8463818_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000001606 210.0
TLS3_k127_849104_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.63e-227 711.0
TLS3_k127_849104_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 385.0
TLS3_k127_849104_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001042 272.0
TLS3_k127_849104_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000001572 124.0
TLS3_k127_8500162_0 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000003978 141.0
TLS3_k127_8500162_1 Beta-lactamase enzyme family - - - 0.000000000000000000000004078 108.0
TLS3_k127_8531040_0 ABC transporter K06158 - - 1.92e-258 812.0
TLS3_k127_8531040_1 TIGRFAM gliding motility-associated protein GldM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 546.0
TLS3_k127_8531040_2 TIGRFAM gliding motility associated protien GldN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 428.0
TLS3_k127_8536262_0 Sulfate permease K03321 - - 2.069e-272 846.0
TLS3_k127_8536262_1 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 1.228e-223 713.0
TLS3_k127_8536262_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 433.0
TLS3_k127_8536262_3 fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 386.0
TLS3_k127_8536262_4 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000005321 196.0
TLS3_k127_8536262_5 Cold shock protein domain - - - 0.000000000000000000000000000000001116 134.0
TLS3_k127_8536262_6 Cold-shock protein K03704 - - 0.00000000000000000000004013 99.0
TLS3_k127_8536262_7 - - - - 0.0000000000000000001545 97.0
TLS3_k127_8536262_8 - - - - 0.00000000007717 63.0
TLS3_k127_854862_0 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 372.0
TLS3_k127_854862_1 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000009139 198.0
TLS3_k127_854862_2 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000000000000000003397 169.0
TLS3_k127_854862_3 pfam nudix - - - 0.00000000000000000000000000000003631 131.0
TLS3_k127_854862_4 - - - - 0.000000000000000000000000000000714 142.0
TLS3_k127_854862_5 Outer membrane protein beta-barrel domain - - - 0.0000002113 60.0
TLS3_k127_8556807_0 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001647 217.0
TLS3_k127_8556807_1 - - - - 0.0008605 49.0
TLS3_k127_8556921_0 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 607.0
TLS3_k127_8556921_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
TLS3_k127_8583311_0 protein of Photorhabdus and some similarities with - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 385.0
TLS3_k127_8583311_1 protein and some similarities with VgrG protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 301.0
TLS3_k127_8583311_2 protein of Photorhabdus and some similarities with - - - 0.00000000000000000000000000000000000000000000000000000004413 219.0
TLS3_k127_8583311_3 PAAR motif - - - 0.00000000000000000000000000000000000000000000000000000007181 197.0
TLS3_k127_8583311_4 LysM domain - - - 0.0000000000000000000000000000000000000000002937 162.0
TLS3_k127_8583311_5 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000001075 123.0
TLS3_k127_8583311_6 tail collar domain protein - - - 0.0000608 53.0
TLS3_k127_882751_0 Ftsk_gamma K03466 - - 7.852e-281 872.0
TLS3_k127_882751_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 478.0
TLS3_k127_882751_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
TLS3_k127_898475_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.104e-200 630.0
TLS3_k127_898475_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 384.0
TLS3_k127_898475_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 267.0
TLS3_k127_898475_3 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000001413 237.0
TLS3_k127_898475_4 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000002468 163.0
TLS3_k127_908278_0 Carbon-nitrogen hydrolase - - - 8.356e-302 929.0
TLS3_k127_908278_1 Multicopper oxidase - - - 3.255e-255 790.0
TLS3_k127_908278_2 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002247 302.0
TLS3_k127_908278_3 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000002228 214.0
TLS3_k127_908278_4 Membrane - - - 0.00000000000000000000000000000000000000000000000003216 197.0
TLS3_k127_908278_5 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000002518 147.0
TLS3_k127_957585_0 Squalene-hopene cyclase N-terminal domain K01852 - 5.4.99.7 0.0 1289.0
TLS3_k127_957585_1 Domain of unknown function (DUF4143) K07133 - - 6.686e-284 873.0
TLS3_k127_957585_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002739 243.0
TLS3_k127_957585_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000003004 115.0
TLS3_k127_958526_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 486.0
TLS3_k127_958526_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 454.0
TLS3_k127_958526_2 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 413.0
TLS3_k127_958526_3 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 335.0
TLS3_k127_958526_4 - - - - 0.0000000000000000000000000000000000000000003395 160.0
TLS3_k127_958526_5 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000001382 162.0
TLS3_k127_958526_6 YceI-like domain - - - 0.00000000000000000000000000000000000002516 151.0
TLS3_k127_958526_7 - - - - 0.000000000000000000001224 104.0
TLS3_k127_960932_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1240.0
TLS3_k127_960932_2 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000000001508 175.0
TLS3_k127_960932_3 Serine aminopeptidase, S33 - - - 0.0000000001942 63.0
TLS3_k127_973196_0 Membrane protein involved in D-alanine export K19294 - - 5.023e-215 682.0
TLS3_k127_973196_1 LysM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 497.0
TLS3_k127_973196_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000008283 186.0
TLS3_k127_973196_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000003521 124.0
TLS3_k127_977736_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 548.0
TLS3_k127_977736_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 422.0
TLS3_k127_977736_10 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.00000000000000000000000000000001569 130.0
TLS3_k127_977736_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000003663 114.0
TLS3_k127_977736_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 421.0
TLS3_k127_977736_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 397.0
TLS3_k127_977736_4 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 301.0
TLS3_k127_977736_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004047 250.0
TLS3_k127_977736_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000005349 243.0
TLS3_k127_977736_7 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006836 200.0
TLS3_k127_977736_8 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000004154 171.0
TLS3_k127_977736_9 RNA-binding protein - - - 0.000000000000000000000000000000012 130.0
TLS3_k127_985669_0 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 497.0