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Overview

ID MAG04068
Name TLS3_bin.9
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Actinomycetes
Order Actinomycetales
Family Dermatophilaceae
Genus F2B08
Species
Assembly information
Completeness (%) 89.2
Contamination (%) 0.55
GC content (%) 71.0
N50 (bp) 20,822
Genome size (bp) 3,147,833

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2923

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1044576_0 AMP-binding enzyme - - - 0.0 1072.0
TLS3_k127_1044576_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 1.83e-254 812.0
TLS3_k127_1044576_10 Ribosome-associated protein Y (PSrp-1) - - - 0.0000000001082 72.0
TLS3_k127_1044576_2 PFAM Metallo-beta-lactamase superfamily - - - 2.388e-209 669.0
TLS3_k127_1044576_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 577.0
TLS3_k127_1044576_4 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 500.0
TLS3_k127_1044576_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 448.0
TLS3_k127_1044576_6 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 333.0
TLS3_k127_1044576_7 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 340.0
TLS3_k127_1044576_8 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.000000000000000000000000000000000000000000000000000001691 196.0
TLS3_k127_1044576_9 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000002817 98.0
TLS3_k127_1049480_0 DNA ligase - - - 0.0 1145.0
TLS3_k127_1049480_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1060.0
TLS3_k127_1049480_10 Na+ dependent nucleoside transporter C-terminus K03317,K11535,K16323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 535.0
TLS3_k127_1049480_11 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 466.0
TLS3_k127_1049480_12 membrane K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 464.0
TLS3_k127_1049480_13 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 458.0
TLS3_k127_1049480_14 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 426.0
TLS3_k127_1049480_15 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 434.0
TLS3_k127_1049480_16 Chlorite dismutase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 418.0
TLS3_k127_1049480_17 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 407.0
TLS3_k127_1049480_18 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 300.0
TLS3_k127_1049480_19 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005234 283.0
TLS3_k127_1049480_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.501e-317 989.0
TLS3_k127_1049480_20 Peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004259 269.0
TLS3_k127_1049480_21 Protein of unknown function (DUF3000) - - - 0.000000000000000000000000000000000000000000000000000000000000000001508 235.0
TLS3_k127_1049480_22 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
TLS3_k127_1049480_23 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000001789 166.0
TLS3_k127_1049480_24 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.00000000000000000000000000000000000003875 148.0
TLS3_k127_1049480_25 RibD C-terminal domain K00082 - 1.1.1.193 0.000000000000000000000000000000000002465 156.0
TLS3_k127_1049480_26 - - - - 0.000000000000000000000000000000001739 134.0
TLS3_k127_1049480_27 - - - - 0.000000000003531 72.0
TLS3_k127_1049480_3 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 - 2.5.1.7 4.39e-280 866.0
TLS3_k127_1049480_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 4.682e-225 703.0
TLS3_k127_1049480_5 N-terminal domain of (some) glycogen debranching enzymes - - - 1.063e-198 642.0
TLS3_k127_1049480_6 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 591.0
TLS3_k127_1049480_7 ABC transporter K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 578.0
TLS3_k127_1049480_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 567.0
TLS3_k127_1049480_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 570.0
TLS3_k127_105365_0 amidohydrolase - - - 4.718e-259 809.0
TLS3_k127_105365_1 RNA helicase - - - 4.376e-211 666.0
TLS3_k127_105365_10 - - - - 0.00000000000000000000000000000000001571 151.0
TLS3_k127_105365_2 L-carnitine dehydratase bile acid-inducible protein F - - - 2.879e-194 614.0
TLS3_k127_105365_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 553.0
TLS3_k127_105365_4 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 484.0
TLS3_k127_105365_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 421.0
TLS3_k127_105365_6 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001125 254.0
TLS3_k127_105365_7 - - - - 0.00000000000000000000000000000000000000000000000000000000001342 210.0
TLS3_k127_105365_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000006446 160.0
TLS3_k127_105365_9 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000006344 155.0
TLS3_k127_1154630_0 4-alpha-glucanotransferase K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 8.541e-260 819.0
TLS3_k127_1154630_1 PTS system sugar-specific permease component K03475 - - 5.852e-235 737.0
TLS3_k127_1154630_10 Domain of unknown function (DUF4177) - - - 0.00000000000000000000000003126 122.0
TLS3_k127_1154630_11 Universal stress protein - - - 0.0000000000000002433 85.0
TLS3_k127_1154630_12 - - - - 0.000000000001025 70.0
TLS3_k127_1154630_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 1.706e-200 632.0
TLS3_k127_1154630_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 576.0
TLS3_k127_1154630_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 376.0
TLS3_k127_1154630_5 amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 382.0
TLS3_k127_1154630_6 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 331.0
TLS3_k127_1154630_7 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
TLS3_k127_1154630_8 ABC transporter (Permease) K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000171 246.0
TLS3_k127_1154630_9 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000113 154.0
TLS3_k127_116146_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 8.161e-229 734.0
TLS3_k127_116146_1 Domain of unknown function (DUF2088) - - - 2.823e-216 679.0
TLS3_k127_116146_2 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 369.0
TLS3_k127_116146_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 357.0
TLS3_k127_116146_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000005504 54.0
TLS3_k127_1248937_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.15,6.4.1.3 2.566e-231 719.0
TLS3_k127_1248937_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 602.0
TLS3_k127_1248937_10 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000002403 152.0
TLS3_k127_1248937_2 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 601.0
TLS3_k127_1248937_3 adenylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 405.0
TLS3_k127_1248937_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
TLS3_k127_1248937_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 334.0
TLS3_k127_1248937_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 263.0
TLS3_k127_1248937_7 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000006195 218.0
TLS3_k127_1248937_8 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001066 217.0
TLS3_k127_1248937_9 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000001265 208.0
TLS3_k127_1270391_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.023e-241 769.0
TLS3_k127_1270391_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 365.0
TLS3_k127_1270391_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008306 274.0
TLS3_k127_1297770_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 401.0
TLS3_k127_1297770_1 the major facilitator superfamily K18926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 409.0
TLS3_k127_1297770_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 394.0
TLS3_k127_1297770_3 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002225 271.0
TLS3_k127_1297770_4 MafB19-like deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000004465 203.0
TLS3_k127_1297770_5 - - - - 0.000000000000000000000000000000000000000003391 160.0
TLS3_k127_1297770_6 Cupin domain K08641,K11312 - 3.4.13.22 0.000000000000000000000000000000000000000009528 160.0
TLS3_k127_1297770_7 Protein of unknown function (DUF2945) - - - 0.00000000000000000000000000002226 122.0
TLS3_k127_1297770_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000002497 113.0
TLS3_k127_1297770_9 HNH nucleases - - - 0.0000000000004346 71.0
TLS3_k127_1307543_0 trehalose synthase K01187,K05341,K05343 - 2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 573.0
TLS3_k127_1307543_1 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 507.0
TLS3_k127_1307543_10 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000000000000003295 143.0
TLS3_k127_1307543_11 - - - - 0.0000000000000000000000005287 120.0
TLS3_k127_1307543_12 regulatory protein, arsR - - - 0.000000000000000000000003274 105.0
TLS3_k127_1307543_13 HNH endonuclease - - - 0.00000000000004449 76.0
TLS3_k127_1307543_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 441.0
TLS3_k127_1307543_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 323.0
TLS3_k127_1307543_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
TLS3_k127_1307543_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001056 260.0
TLS3_k127_1307543_6 PFAM methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000007826 241.0
TLS3_k127_1307543_7 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000000001199 220.0
TLS3_k127_1307543_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000001021 171.0
TLS3_k127_1307543_9 Matrixin - - - 0.000000000000000000000000000000000000000000002128 173.0
TLS3_k127_1312568_0 Sodium glutamate symporter K03312 - - 1.105e-253 789.0
TLS3_k127_1312568_1 helix_turn_helix, Lux Regulon K03556 - - 6.944e-250 799.0
TLS3_k127_1312568_10 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000005623 204.0
TLS3_k127_1312568_11 cyclic nucleotide binding - - - 0.00000000000000000000000000000000000000000000001066 183.0
TLS3_k127_1312568_12 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000001343 168.0
TLS3_k127_1312568_13 - - - - 0.0000000000000000000000000000000000000000001352 173.0
TLS3_k127_1312568_14 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000001232 91.0
TLS3_k127_1312568_15 - - - - 0.00000001982 61.0
TLS3_k127_1312568_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.724e-246 770.0
TLS3_k127_1312568_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 504.0
TLS3_k127_1312568_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 486.0
TLS3_k127_1312568_5 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 411.0
TLS3_k127_1312568_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 413.0
TLS3_k127_1312568_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004338 282.0
TLS3_k127_1312568_8 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
TLS3_k127_1312568_9 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000001505 241.0
TLS3_k127_1323306_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1411.0
TLS3_k127_1323306_1 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 0.0 1278.0
TLS3_k127_1323306_10 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 289.0
TLS3_k127_1323306_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004845 245.0
TLS3_k127_1323306_12 Domain of unknown function (DUF1931) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001493 232.0
TLS3_k127_1323306_13 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
TLS3_k127_1323306_14 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000001042 212.0
TLS3_k127_1323306_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000001204 199.0
TLS3_k127_1323306_16 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000001055 145.0
TLS3_k127_1323306_17 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000001092 121.0
TLS3_k127_1323306_18 Transglycosylase associated protein - - - 0.0000000000000003875 80.0
TLS3_k127_1323306_19 Domain of unknown function (DUF397) - - - 0.0000000000001772 76.0
TLS3_k127_1323306_2 Heat shock 70 kDa protein K04043 - - 1.146e-321 1005.0
TLS3_k127_1323306_3 Cyclic nucleotide-monophosphate binding domain K00384 - 1.8.1.9 3.532e-253 798.0
TLS3_k127_1323306_4 PFAM Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 1.538e-241 751.0
TLS3_k127_1323306_5 Alcohol dehydrogenase GroES-associated - - - 2.957e-237 745.0
TLS3_k127_1323306_6 PucR C-terminal helix-turn-helix domain - - - 1.162e-196 625.0
TLS3_k127_1323306_7 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 450.0
TLS3_k127_1323306_8 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 345.0
TLS3_k127_1323306_9 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 326.0
TLS3_k127_1374117_0 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 301.0
TLS3_k127_1374117_1 Signal transduction histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
TLS3_k127_1374117_2 response to pH - - - 0.00000000000000000000000000000000000000000000000003817 195.0
TLS3_k127_1393877_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.0 1177.0
TLS3_k127_1393877_1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1140.0
TLS3_k127_1393877_10 GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 501.0
TLS3_k127_1393877_11 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 498.0
TLS3_k127_1393877_12 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 485.0
TLS3_k127_1393877_13 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 446.0
TLS3_k127_1393877_14 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 419.0
TLS3_k127_1393877_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 413.0
TLS3_k127_1393877_16 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 383.0
TLS3_k127_1393877_17 Permeases of the drug metabolite transporter DMT superfamily K15269 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
TLS3_k127_1393877_18 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 351.0
TLS3_k127_1393877_19 HIT family hydrolase K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 313.0
TLS3_k127_1393877_2 Dienelactone hydrolase family - - - 6.051e-274 859.0
TLS3_k127_1393877_20 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
TLS3_k127_1393877_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 287.0
TLS3_k127_1393877_22 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003019 265.0
TLS3_k127_1393877_23 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001112 247.0
TLS3_k127_1393877_24 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
TLS3_k127_1393877_25 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004985 251.0
TLS3_k127_1393877_26 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000001503 230.0
TLS3_k127_1393877_27 PFAM Abortive infection protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001738 231.0
TLS3_k127_1393877_28 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000008414 224.0
TLS3_k127_1393877_29 LemA family - - - 0.0000000000000000000000000000000000000000000000000000001816 199.0
TLS3_k127_1393877_3 Amidase K01426 - 3.5.1.4 2.563e-268 835.0
TLS3_k127_1393877_30 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000005678 204.0
TLS3_k127_1393877_31 SnoaL-like domain - - - 0.000000000000000000000000000000000003817 141.0
TLS3_k127_1393877_32 Zn_pept - - - 0.00000000000000000000000000001043 127.0
TLS3_k127_1393877_33 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000000000003111 117.0
TLS3_k127_1393877_35 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000004374 102.0
TLS3_k127_1393877_36 - - - - 0.00000000000000000895 92.0
TLS3_k127_1393877_37 Predicted membrane protein (DUF2207) - - - 0.000000000000001636 85.0
TLS3_k127_1393877_38 Zn_pept - - - 0.00000000000006886 79.0
TLS3_k127_1393877_39 Transposase, Mutator family - - - 0.00000000000007735 72.0
TLS3_k127_1393877_4 Sigma-70 region 2 K03088 - - 4.231e-264 823.0
TLS3_k127_1393877_40 Antibiotic biosynthesis monooxygenase - - - 0.00000000000008508 82.0
TLS3_k127_1393877_41 - - - - 0.00000000000107 75.0
TLS3_k127_1393877_42 Zn_pept - - - 0.0000000003716 68.0
TLS3_k127_1393877_43 - - - - 0.0002762 46.0
TLS3_k127_1393877_5 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 1.031e-212 681.0
TLS3_k127_1393877_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 585.0
TLS3_k127_1393877_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 560.0
TLS3_k127_1393877_8 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 540.0
TLS3_k127_1393877_9 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 535.0
TLS3_k127_158106_0 beta-galactosidase K12308 - 3.2.1.23 1.948e-276 872.0
TLS3_k127_158106_1 acetyl-CoA carboxylase K01962,K01963 - 2.1.3.15,6.4.1.2 9.224e-247 776.0
TLS3_k127_158106_10 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000004029 201.0
TLS3_k127_158106_2 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 8.544e-200 631.0
TLS3_k127_158106_3 Bacterial extracellular solute-binding protein K02027 - - 1.907e-195 618.0
TLS3_k127_158106_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 524.0
TLS3_k127_158106_5 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 493.0
TLS3_k127_158106_6 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 452.0
TLS3_k127_158106_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 425.0
TLS3_k127_158106_8 Bacterial regulatory proteins, deoR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003925 291.0
TLS3_k127_158106_9 Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid K03383,K19794 - 3.5.2.1,3.5.2.15 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
TLS3_k127_1595863_0 Glycosyltransferase 36 associated - - - 0.0 1535.0
TLS3_k127_1595863_1 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.029e-303 940.0
TLS3_k127_1595863_2 synthetase K01897 - 6.2.1.3 9.607e-239 760.0
TLS3_k127_1595863_3 Putative glucoamylase - - - 4.283e-227 712.0
TLS3_k127_1595863_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 456.0
TLS3_k127_1595863_5 ABC-type branched-chain amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 425.0
TLS3_k127_1595863_6 amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 346.0
TLS3_k127_1595863_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 314.0
TLS3_k127_1595863_8 amino acid K01996 - - 0.0000000000000128 74.0
TLS3_k127_1644119_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 572.0
TLS3_k127_1644119_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 566.0
TLS3_k127_1644119_10 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000004179 143.0
TLS3_k127_1644119_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 526.0
TLS3_k127_1644119_3 Esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 372.0
TLS3_k127_1644119_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 334.0
TLS3_k127_1644119_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
TLS3_k127_1644119_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
TLS3_k127_1644119_7 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
TLS3_k127_1644119_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001179 219.0
TLS3_k127_1644119_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000002249 165.0
TLS3_k127_168827_0 Aminotransferase class-V - - - 6.789e-254 793.0
TLS3_k127_168827_1 SNF2 family N-terminal domain - - - 1.45e-249 815.0
TLS3_k127_168827_10 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 293.0
TLS3_k127_168827_11 ASCH - - - 0.0000000000000000000000000000000000000000000000000000000000000009666 224.0
TLS3_k127_168827_12 MT0933-like antitoxin protein - - - 0.00000000000000824 83.0
TLS3_k127_168827_13 cyclase dehydrase - - - 0.0000000000002827 76.0
TLS3_k127_168827_2 FAD dependent oxidoreductase - - - 2.725e-205 653.0
TLS3_k127_168827_3 Glycine betaine ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 587.0
TLS3_k127_168827_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 360.0
TLS3_k127_168827_5 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 353.0
TLS3_k127_168827_6 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 329.0
TLS3_k127_168827_7 ABC transporter (Permease) K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 311.0
TLS3_k127_168827_8 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 308.0
TLS3_k127_168827_9 ABC transporter (Permease) K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
TLS3_k127_1719722_0 ABC transporter K02004 - - 8.623e-273 868.0
TLS3_k127_1719722_1 PhoD-like phosphatase - - - 7.282e-242 759.0
TLS3_k127_1719722_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 474.0
TLS3_k127_1719722_3 ATP-grasp K17810 - 6.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 437.0
TLS3_k127_1719722_4 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 382.0
TLS3_k127_1719722_5 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002482 252.0
TLS3_k127_1766689_0 Fe-S oxidoreductase - - - 0.0 1238.0
TLS3_k127_1766689_1 Peptidase family M3 K01284 - 3.4.15.5 0.0 1075.0
TLS3_k127_1766689_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 4.55e-217 691.0
TLS3_k127_1766689_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 520.0
TLS3_k127_1766689_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 475.0
TLS3_k127_1766689_5 Serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
TLS3_k127_1766689_6 Cold-shock protein K03704 - - 0.00000000000000000000000000000000836 130.0
TLS3_k127_1766689_7 - - - - 0.0000000000000000000002459 104.0
TLS3_k127_1785188_0 ABC transporter transmembrane region K02021,K06147,K16786,K16787 - - 2.827e-306 957.0
TLS3_k127_1785188_1 ABC transporter transmembrane region - - - 2.83e-306 949.0
TLS3_k127_1785188_10 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 302.0
TLS3_k127_1785188_11 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
TLS3_k127_1785188_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K11608 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000006261 259.0
TLS3_k127_1785188_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
TLS3_k127_1785188_14 Protein of unknown function (DUF3145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004157 241.0
TLS3_k127_1785188_15 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000004937 208.0
TLS3_k127_1785188_16 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000003034 208.0
TLS3_k127_1785188_18 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000003192 182.0
TLS3_k127_1785188_19 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000000624 175.0
TLS3_k127_1785188_2 AMP-binding enzyme C-terminal domain K00666 - - 3.368e-275 857.0
TLS3_k127_1785188_20 Nitroreductase family - - - 0.0000000000000000000000000000000000000000001948 178.0
TLS3_k127_1785188_21 Peptidase M15 K08640 - 3.4.17.14 0.000000000000000000000000000000001153 138.0
TLS3_k127_1785188_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.000000000000000000000000000000005931 138.0
TLS3_k127_1785188_23 Dodecin K09165 - - 0.0000000000000000000000989 103.0
TLS3_k127_1785188_24 - - - - 0.00000009795 59.0
TLS3_k127_1785188_3 Propionyl-CoA carboxylase subunit beta K18472 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494 2.1.3.15,6.4.1.2,6.4.1.3 4.242e-262 813.0
TLS3_k127_1785188_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 582.0
TLS3_k127_1785188_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 584.0
TLS3_k127_1785188_6 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 561.0
TLS3_k127_1785188_7 Major Facilitator K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 511.0
TLS3_k127_1785188_8 ATP-binding protein K10008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 429.0
TLS3_k127_1785188_9 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 336.0
TLS3_k127_1807217_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 561.0
TLS3_k127_1807217_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 469.0
TLS3_k127_1807217_10 Putative transmembrane protein (PGPGW) - - - 0.0000792 51.0
TLS3_k127_1807217_2 tail sheath protein K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 465.0
TLS3_k127_1807217_3 ABC transporter, ATP-binding protein K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 412.0
TLS3_k127_1807217_4 ABC transporter (Permease) K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 414.0
TLS3_k127_1807217_5 LPXTG-motif cell wall anchor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 338.0
TLS3_k127_1807217_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 317.0
TLS3_k127_1807217_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
TLS3_k127_1807217_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000002962 222.0
TLS3_k127_1807217_9 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000001458 104.0
TLS3_k127_1821959_0 Multidrug ABC transporter ATPase K06147 - - 6.868e-261 818.0
TLS3_k127_1821959_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 496.0
TLS3_k127_1821959_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 321.0
TLS3_k127_1821959_3 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 279.0
TLS3_k127_1821959_4 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
TLS3_k127_1821959_5 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000173 200.0
TLS3_k127_1821959_6 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000001263 148.0
TLS3_k127_1821959_7 Haem-degrading - - - 0.00000000000000000000000000000002502 131.0
TLS3_k127_1821959_8 MarR family transcriptional regulator - - - 0.00000000000000000000000003634 115.0
TLS3_k127_1824673_0 Phosphotransferase system, EIIC K02768,K02769,K02770 - 2.7.1.202 3e-323 1001.0
TLS3_k127_1824673_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.268e-264 829.0
TLS3_k127_1824673_10 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 325.0
TLS3_k127_1824673_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 317.0
TLS3_k127_1824673_12 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000008462 238.0
TLS3_k127_1824673_13 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
TLS3_k127_1824673_14 Vitamin K epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000004604 211.0
TLS3_k127_1824673_15 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0071702 - 0.0000000000000000000000000000000000000189 147.0
TLS3_k127_1824673_16 ATPases associated with a variety of cellular activities K15738 - - 0.00000000000001089 74.0
TLS3_k127_1824673_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 4.65e-233 731.0
TLS3_k127_1824673_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 2.57e-222 698.0
TLS3_k127_1824673_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 611.0
TLS3_k127_1824673_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 556.0
TLS3_k127_1824673_6 Phosphomethylpyrimidine kinase K00882,K16370 - 2.7.1.11,2.7.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 412.0
TLS3_k127_1824673_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 378.0
TLS3_k127_1824673_8 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 357.0
TLS3_k127_1824673_9 Trans-aconitate methyltransferase K00598 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 335.0
TLS3_k127_1840141_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0 1208.0
TLS3_k127_1840141_1 mechanosensitive ion channel protein MscS K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 390.0
TLS3_k127_1840141_10 - - - - 0.000003363 50.0
TLS3_k127_1840141_2 Major Facilitator Superfamily K03449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 316.0
TLS3_k127_1840141_3 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 308.0
TLS3_k127_1840141_4 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001794 303.0
TLS3_k127_1840141_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006076 284.0
TLS3_k127_1840141_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
TLS3_k127_1840141_7 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000005245 248.0
TLS3_k127_1840141_8 alpha-glucosidase K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
TLS3_k127_1840141_9 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000001054 216.0
TLS3_k127_1917270_0 ATP-dependent helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 0.0 1027.0
TLS3_k127_1917270_1 Iron ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 588.0
TLS3_k127_1917270_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000959 137.0
TLS3_k127_1917270_11 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000002177 128.0
TLS3_k127_1917270_12 Transglycosylase associated protein - - - 0.0000000000000000000000000001096 118.0
TLS3_k127_1917270_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 550.0
TLS3_k127_1917270_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 428.0
TLS3_k127_1917270_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 409.0
TLS3_k127_1917270_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
TLS3_k127_1917270_6 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 336.0
TLS3_k127_1917270_7 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
TLS3_k127_1917270_8 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000006884 164.0
TLS3_k127_1917270_9 Acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000001119 175.0
TLS3_k127_1935197_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 317.0
TLS3_k127_1935197_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 309.0
TLS3_k127_1935197_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000001067 128.0
TLS3_k127_1935197_3 Protein of unknown function (DUF3117) - - - 0.00000000000000000000000007431 108.0
TLS3_k127_1937709_0 Butyryl-CoA dehydrogenase - - - 0.0 1076.0
TLS3_k127_1937709_1 the major facilitator superfamily - - - 8.773e-270 845.0
TLS3_k127_1937709_10 N-acetyltransferase GCN5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 467.0
TLS3_k127_1937709_11 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 455.0
TLS3_k127_1937709_12 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 448.0
TLS3_k127_1937709_13 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 441.0
TLS3_k127_1937709_14 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 432.0
TLS3_k127_1937709_15 KR domain K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 319.0
TLS3_k127_1937709_16 apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 318.0
TLS3_k127_1937709_17 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 280.0
TLS3_k127_1937709_18 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
TLS3_k127_1937709_19 Fructose transport system kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004224 258.0
TLS3_k127_1937709_2 Cytochrome C oxidase assembly protein K02351,K07245 - - 4.07e-234 747.0
TLS3_k127_1937709_20 Rifampin ADP-ribosyl transferase K19062 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003989 243.0
TLS3_k127_1937709_21 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000417 245.0
TLS3_k127_1937709_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 246.0
TLS3_k127_1937709_23 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
TLS3_k127_1937709_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000276 233.0
TLS3_k127_1937709_25 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000000000000009473 219.0
TLS3_k127_1937709_26 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000438 204.0
TLS3_k127_1937709_27 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000007675 163.0
TLS3_k127_1937709_28 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000003722 166.0
TLS3_k127_1937709_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000009846 140.0
TLS3_k127_1937709_3 Belongs to the RimK family K05827,K05844 - 6.3.2.43 1.027e-212 670.0
TLS3_k127_1937709_30 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000003768 141.0
TLS3_k127_1937709_31 - - - - 0.00000000000000000000025 108.0
TLS3_k127_1937709_32 Protein of unknown function (DUF2568) - - - 0.00000000000249 72.0
TLS3_k127_1937709_4 mannose-ethanolamine phosphotransferase activity - - - 6.799e-211 664.0
TLS3_k127_1937709_5 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 583.0
TLS3_k127_1937709_6 D-amino acid K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 514.0
TLS3_k127_1937709_7 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 518.0
TLS3_k127_1937709_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 493.0
TLS3_k127_1937709_9 Succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 489.0
TLS3_k127_19657_0 FAD binding domain - - - 2.602e-217 683.0
TLS3_k127_19657_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 564.0
TLS3_k127_19657_2 WD40 repeats - - - 0.0000000000000000000000000000008233 137.0
TLS3_k127_1987377_0 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 612.0
TLS3_k127_1987377_1 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 494.0
TLS3_k127_1987377_10 - - - - 0.00001292 57.0
TLS3_k127_1987377_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 348.0
TLS3_k127_1987377_3 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004762 258.0
TLS3_k127_1987377_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000004262 205.0
TLS3_k127_1987377_5 DNA helicase - - - 0.000000000000000000000000000000000000000000000000000001154 216.0
TLS3_k127_1987377_6 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000005801 178.0
TLS3_k127_1987377_7 - - - - 0.00000000000002322 74.0
TLS3_k127_1987377_9 - - - - 0.00000006728 58.0
TLS3_k127_2022752_0 ABC transporter K06147 - - 1.89e-299 932.0
TLS3_k127_2022752_1 ABC transporter transmembrane region K06147 - - 6.003e-284 891.0
TLS3_k127_2022752_10 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000001264 112.0
TLS3_k127_2022752_2 Multidrug ABC transporter ATP-binding protein K06147 - - 3.891e-224 708.0
TLS3_k127_2022752_3 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 539.0
TLS3_k127_2022752_4 GDP-mannose 4,6 dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 446.0
TLS3_k127_2022752_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 400.0
TLS3_k127_2022752_7 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 309.0
TLS3_k127_2022752_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 312.0
TLS3_k127_2066406_0 Histidine ammonia-lyase K01745 - 4.3.1.3 4.332e-247 774.0
TLS3_k127_2066406_1 metal ion transport - - - 1.879e-216 687.0
TLS3_k127_2066406_10 - - - - 0.0000000000000000000000000006036 125.0
TLS3_k127_2066406_11 Short C-terminal domain - - - 0.00000000000000009628 85.0
TLS3_k127_2066406_12 META domain - - - 0.000000000000001565 82.0
TLS3_k127_2066406_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 582.0
TLS3_k127_2066406_3 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 484.0
TLS3_k127_2066406_4 ATPases associated with a variety of cellular activities K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 366.0
TLS3_k127_2066406_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 333.0
TLS3_k127_2066406_6 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 302.0
TLS3_k127_2066406_7 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 305.0
TLS3_k127_2066406_8 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001394 275.0
TLS3_k127_2066406_9 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002401 234.0
TLS3_k127_2105756_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1114.0
TLS3_k127_2105756_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 5.965e-232 750.0
TLS3_k127_2105756_10 Coenzyme F420-dependent NADP oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 375.0
TLS3_k127_2105756_11 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 364.0
TLS3_k127_2105756_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 340.0
TLS3_k127_2105756_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 325.0
TLS3_k127_2105756_14 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 342.0
TLS3_k127_2105756_15 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 321.0
TLS3_k127_2105756_16 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
TLS3_k127_2105756_17 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 311.0
TLS3_k127_2105756_18 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 319.0
TLS3_k127_2105756_19 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
TLS3_k127_2105756_2 proteinase - - - 2.127e-200 640.0
TLS3_k127_2105756_20 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000000000000000002461 161.0
TLS3_k127_2105756_21 Protein of unknown function (DUF3180) - - - 0.000000000000000000000000000003758 132.0
TLS3_k127_2105756_22 family transcriptional regulator K13652 - - 0.00000000000000000000000000001742 124.0
TLS3_k127_2105756_23 - - - - 0.000000000000000000000006464 113.0
TLS3_k127_2105756_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000003646 95.0
TLS3_k127_2105756_25 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0008150,GO:0040007 6.1.1.6 0.0000000000000000000006487 97.0
TLS3_k127_2105756_26 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000001203 90.0
TLS3_k127_2105756_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 594.0
TLS3_k127_2105756_4 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 572.0
TLS3_k127_2105756_5 DNA polymerase III subunit delta K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 548.0
TLS3_k127_2105756_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 493.0
TLS3_k127_2105756_7 Coenzyme F420 biosynthesis-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 481.0
TLS3_k127_2105756_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 404.0
TLS3_k127_2105756_9 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 382.0
TLS3_k127_2121379_0 Helicase K10843 - 3.6.4.12 5.395e-264 818.0
TLS3_k127_2121379_1 permease K06901 - - 5.704e-239 748.0
TLS3_k127_2121379_10 Protein of unknown function (DUF3027) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 361.0
TLS3_k127_2121379_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 354.0
TLS3_k127_2121379_12 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000009291 257.0
TLS3_k127_2121379_13 Cold-shock protein K03704 - - 0.00000000000000000000000000000000000000000000000002867 197.0
TLS3_k127_2121379_14 Beta-lactamase - - - 0.00000000000000000000000000000000000002569 156.0
TLS3_k127_2121379_15 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000001161 144.0
TLS3_k127_2121379_16 Protein of unknown function (DUF2530) - - - 0.00000000000000000000001911 102.0
TLS3_k127_2121379_17 - - - - 0.00000000000000000000006232 106.0
TLS3_k127_2121379_18 - - - - 0.0000000001907 70.0
TLS3_k127_2121379_2 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 9.387e-203 637.0
TLS3_k127_2121379_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 1.528e-197 628.0
TLS3_k127_2121379_4 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 606.0
TLS3_k127_2121379_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 563.0
TLS3_k127_2121379_6 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 552.0
TLS3_k127_2121379_7 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 482.0
TLS3_k127_2121379_8 Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 387.0
TLS3_k127_2121379_9 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 363.0
TLS3_k127_2292509_0 Helicase - - - 0.0 1087.0
TLS3_k127_2292509_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 601.0
TLS3_k127_2292509_10 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 274.0
TLS3_k127_2292509_11 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 254.0
TLS3_k127_2292509_12 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000006873 256.0
TLS3_k127_2292509_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001143 206.0
TLS3_k127_2292509_14 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000000000000000004423 190.0
TLS3_k127_2292509_15 Domain of unknown function (DUF1876) - - - 0.000000000000000000000000000000000000000000000000001225 187.0
TLS3_k127_2292509_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000003495 180.0
TLS3_k127_2292509_17 Aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000006775 166.0
TLS3_k127_2292509_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000002064 136.0
TLS3_k127_2292509_19 Winged helix DNA-binding domain - - - 0.0000000000000000000000000001579 129.0
TLS3_k127_2292509_2 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 578.0
TLS3_k127_2292509_20 response to abiotic stimulus - - - 0.000000000000000000000002759 116.0
TLS3_k127_2292509_21 - - - - 0.0000000000000000601 93.0
TLS3_k127_2292509_22 - - - - 0.000000000004475 73.0
TLS3_k127_2292509_3 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 486.0
TLS3_k127_2292509_4 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 508.0
TLS3_k127_2292509_5 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 454.0
TLS3_k127_2292509_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 430.0
TLS3_k127_2292509_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 383.0
TLS3_k127_2292509_8 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 342.0
TLS3_k127_2292509_9 HAD-hyrolase-like K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009403 271.0
TLS3_k127_2299803_0 Alpha-amylase domain - - - 0.0 1024.0
TLS3_k127_2299803_1 ABC transporter - - - 1.303e-305 951.0
TLS3_k127_2299803_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 385.0
TLS3_k127_2299803_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 347.0
TLS3_k127_2299803_4 Protein of unknown function (DUF2993) - - - 0.0000000000000000000000000000000000000000000000000000002052 208.0
TLS3_k127_2299803_5 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000001013 152.0
TLS3_k127_2299803_6 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000006809 110.0
TLS3_k127_239215_0 Catalyzes the transfer of electrons from NADH to quinone K00336 - 1.6.5.3 0.0 1058.0
TLS3_k127_239215_1 ferredoxin oxidoreductase K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4e-323 997.0
TLS3_k127_239215_10 cytochrome C K07399 - - 3.939e-195 621.0
TLS3_k127_239215_11 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 8.554e-195 650.0
TLS3_k127_239215_12 Isochorismate synthase K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 589.0
TLS3_k127_239215_13 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 582.0
TLS3_k127_239215_14 2-oxoacid ferredoxin oxidoreductase subunit beta K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 569.0
TLS3_k127_239215_15 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 488.0
TLS3_k127_239215_16 acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 480.0
TLS3_k127_239215_17 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 497.0
TLS3_k127_239215_18 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 475.0
TLS3_k127_239215_19 Phosphate acyltransferases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 462.0
TLS3_k127_239215_2 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 1.345e-289 904.0
TLS3_k127_239215_20 Alanine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 458.0
TLS3_k127_239215_21 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 450.0
TLS3_k127_239215_22 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0008150,GO:0040007 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 448.0
TLS3_k127_239215_23 epimerase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 439.0
TLS3_k127_239215_24 NADH dehydrogenase subunit E K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 422.0
TLS3_k127_239215_25 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 400.0
TLS3_k127_239215_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 405.0
TLS3_k127_239215_27 cytochrome c biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 404.0
TLS3_k127_239215_28 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 390.0
TLS3_k127_239215_29 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 355.0
TLS3_k127_239215_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 4.135e-248 784.0
TLS3_k127_239215_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 346.0
TLS3_k127_239215_31 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 357.0
TLS3_k127_239215_32 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 314.0
TLS3_k127_239215_33 AMP-binding enzyme C-terminal domain K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 315.0
TLS3_k127_239215_34 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
TLS3_k127_239215_35 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001176 277.0
TLS3_k127_239215_36 YwiC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004729 276.0
TLS3_k127_239215_37 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000095 255.0
TLS3_k127_239215_38 Thiol disulfide interchange protein - - - 0.0000000000000000000000000000000000000000000000000000000007016 216.0
TLS3_k127_239215_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001156 201.0
TLS3_k127_239215_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.023e-247 768.0
TLS3_k127_239215_40 transcriptional regulator - - - 0.000000000000000000000000000000000000000000005169 185.0
TLS3_k127_239215_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000001798 162.0
TLS3_k127_239215_42 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000002317 157.0
TLS3_k127_239215_43 Transmembrane secretion effector - - - 0.0000000000000000000000000000005565 125.0
TLS3_k127_239215_44 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000002936 121.0
TLS3_k127_239215_45 membrane - - - 0.000000000000000000000000005111 113.0
TLS3_k127_239215_46 transcriptional regulator - - - 0.00000000000000000000000002465 108.0
TLS3_k127_239215_47 Protein of unknown function (DUF4229) - - - 0.0000000000000000000829 96.0
TLS3_k127_239215_48 Mitochondrial domain of unknown function (DUF1713) - - - 0.000000009564 56.0
TLS3_k127_239215_5 Uroporphyrin-III C-methyltransferase K01719,K13542 - 2.1.1.107,4.2.1.75 9.498e-225 709.0
TLS3_k127_239215_6 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 2.029e-221 698.0
TLS3_k127_239215_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 1.127e-218 689.0
TLS3_k127_239215_8 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 2.61e-218 689.0
TLS3_k127_239215_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 1.942e-210 670.0
TLS3_k127_2395951_0 Multidrug ABC transporter ATPase - - - 1.376e-268 857.0
TLS3_k127_2395951_1 ABC transporter - - - 4.642e-243 765.0
TLS3_k127_2395951_10 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000003015 138.0
TLS3_k127_2395951_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001508 93.0
TLS3_k127_2395951_2 Aminotransferase K00812,K14267 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.6.1.1,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 606.0
TLS3_k127_2395951_3 Magnesium chelatase, subunit ChlI C-terminal K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 550.0
TLS3_k127_2395951_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 532.0
TLS3_k127_2395951_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 404.0
TLS3_k127_2395951_6 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 339.0
TLS3_k127_2395951_7 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001589 189.0
TLS3_k127_2395951_8 Peptidase family M23 - - - 0.000000000000000000000000000000000000001109 157.0
TLS3_k127_2395951_9 - - - - 0.00000000000000000000000000000000000001038 149.0
TLS3_k127_2442365_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
TLS3_k127_2442365_1 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 321.0
TLS3_k127_2442365_2 Cobalt ABC transporter K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000004133 240.0
TLS3_k127_2442365_3 PDGLE domain K02009 - - 0.0000000000000000000000005105 109.0
TLS3_k127_2442365_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000001097 53.0
TLS3_k127_2446627_0 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 598.0
TLS3_k127_2446627_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 491.0
TLS3_k127_2446627_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008523 242.0
TLS3_k127_2446627_3 biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000003738 223.0
TLS3_k127_2560206_0 DEAD DEAH box helicase K03724 - - 0.0 1814.0
TLS3_k127_2560206_1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 511.0
TLS3_k127_2560206_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 321.0
TLS3_k127_2560206_3 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000006869 223.0
TLS3_k127_2560206_4 Protein of unknown function (DUF3046) - - - 0.0000000000000000000002995 98.0
TLS3_k127_2573165_0 WD40 repeats - - - 0.0 1119.0
TLS3_k127_2573165_1 Cation transporter/ATPase, N-terminus - - - 0.0 1087.0
TLS3_k127_2573165_10 AraC-like ligand binding domain - - - 0.000000000000000000000000000000001235 136.0
TLS3_k127_2573165_11 Sulfurtransferase - - - 0.0000000000000000000000000000007886 128.0
TLS3_k127_2573165_12 Cold shock protein K03704 - - 0.000000000000000000000000000002998 121.0
TLS3_k127_2573165_14 - - - - 0.000000000000000000000003315 109.0
TLS3_k127_2573165_15 Bacterial transcriptional activator domain - - - 0.000000000000000000005925 109.0
TLS3_k127_2573165_17 Two component transcriptional regulator, LuxR family - - - 0.000000002016 71.0
TLS3_k127_2573165_2 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 325.0
TLS3_k127_2573165_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 287.0
TLS3_k127_2573165_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000395 287.0
TLS3_k127_2573165_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001738 287.0
TLS3_k127_2573165_6 Peroxiredoxin K04063 - - 0.00000000000000000000000000000000000000000000000000000000002687 213.0
TLS3_k127_2573165_7 Golgi phosphoprotein 3 (GPP34) - - - 0.00000000000000000000000000000000000000000000000000000001725 204.0
TLS3_k127_2573165_8 - - - - 0.0000000000000000000000000000000000000000000000000000528 199.0
TLS3_k127_2573165_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001685 156.0
TLS3_k127_2604613_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1209.0
TLS3_k127_2604613_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1104.0
TLS3_k127_2604613_10 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 460.0
TLS3_k127_2604613_11 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 406.0
TLS3_k127_2604613_12 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 402.0
TLS3_k127_2604613_13 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 398.0
TLS3_k127_2604613_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 368.0
TLS3_k127_2604613_15 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 368.0
TLS3_k127_2604613_16 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 338.0
TLS3_k127_2604613_17 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 319.0
TLS3_k127_2604613_18 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
TLS3_k127_2604613_19 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008195 274.0
TLS3_k127_2604613_2 Acetolactate synthase K01652 - 2.2.1.6 0.0 1021.0
TLS3_k127_2604613_20 acetolactate synthase K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
TLS3_k127_2604613_21 Phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 257.0
TLS3_k127_2604613_22 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
TLS3_k127_2604613_23 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
TLS3_k127_2604613_24 Protein of unknown function (DUF3618) - - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
TLS3_k127_2604613_25 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000001165 208.0
TLS3_k127_2604613_26 molybdopterin cofactor binding - - - 0.000000000000000000000000000000000000000000000000000007981 198.0
TLS3_k127_2604613_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000002461 198.0
TLS3_k127_2604613_28 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000000000000000000000000000000002937 188.0
TLS3_k127_2604613_29 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000007476 190.0
TLS3_k127_2604613_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 2.876e-272 848.0
TLS3_k127_2604613_30 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000003625 184.0
TLS3_k127_2604613_31 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000006897 155.0
TLS3_k127_2604613_32 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000309 150.0
TLS3_k127_2604613_33 SNARE associated Golgi protein - - - 0.000004848 55.0
TLS3_k127_2604613_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.732e-270 841.0
TLS3_k127_2604613_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.365e-265 850.0
TLS3_k127_2604613_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 2.215e-198 622.0
TLS3_k127_2604613_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 575.0
TLS3_k127_2604613_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 551.0
TLS3_k127_2604613_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 503.0
TLS3_k127_2632761_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1500.0
TLS3_k127_2632761_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 9.638e-317 983.0
TLS3_k127_2632761_10 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 324.0
TLS3_k127_2632761_11 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 320.0
TLS3_k127_2632761_12 cell wall binding repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002015 286.0
TLS3_k127_2632761_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001484 269.0
TLS3_k127_2632761_14 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001513 271.0
TLS3_k127_2632761_15 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
TLS3_k127_2632761_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001196 238.0
TLS3_k127_2632761_17 COG1555 DNA uptake protein and related DNA-binding K02237 - - 0.0000000000000000000000000000000000000000000000000000001183 204.0
TLS3_k127_2632761_18 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000001881 192.0
TLS3_k127_2632761_19 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000001046 166.0
TLS3_k127_2632761_2 Cation transport protein K03498 - - 2.402e-232 727.0
TLS3_k127_2632761_20 Domain of unknown function (DUF4259) - - - 0.000000000000000000000000000000001807 134.0
TLS3_k127_2632761_21 LysM domain - - - 0.000000000003184 72.0
TLS3_k127_2632761_23 Domain of unknown function (DUF4369) - - - 0.000009145 59.0
TLS3_k127_2632761_3 membrane K02238 - - 1.281e-207 674.0
TLS3_k127_2632761_4 Predicted Permease Membrane Region K07085 - - 1.607e-206 655.0
TLS3_k127_2632761_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.118e-198 625.0
TLS3_k127_2632761_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 451.0
TLS3_k127_2632761_7 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 410.0
TLS3_k127_2632761_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 364.0
TLS3_k127_2632761_9 NAD-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 349.0
TLS3_k127_2642555_0 AMP-binding protein K00666 - - 2.839e-272 870.0
TLS3_k127_2642555_1 in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor K00812,K14260 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.1,2.6.1.2,2.6.1.66 2.378e-250 776.0
TLS3_k127_2642555_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
TLS3_k127_2642555_11 Nitrate reductase K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 341.0
TLS3_k127_2642555_12 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 324.0
TLS3_k127_2642555_13 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 317.0
TLS3_k127_2642555_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
TLS3_k127_2642555_15 NlpC/P60 family K21471 - - 0.000000000000000000000000000000000000000000000000000000001339 211.0
TLS3_k127_2642555_16 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000008511 179.0
TLS3_k127_2642555_17 molybdenum cofactor guanylyltransferase activity K03752 - 2.7.7.77 0.0000000000000000000000000000000000000002474 156.0
TLS3_k127_2642555_18 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.0000000000000000000000000001425 117.0
TLS3_k127_2642555_19 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000002005 109.0
TLS3_k127_2642555_2 Acyl-CoA oxidase K00232 - 1.3.3.6 3.861e-221 707.0
TLS3_k127_2642555_20 - - - - 0.0000000000000000001326 102.0
TLS3_k127_2642555_21 molybdenum cofactor guanylyltransferase activity - - - 0.00000000000000001312 86.0
TLS3_k127_2642555_22 - - - - 0.000000001133 64.0
TLS3_k127_2642555_3 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 601.0
TLS3_k127_2642555_4 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 597.0
TLS3_k127_2642555_5 FAD-linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 601.0
TLS3_k127_2642555_6 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 547.0
TLS3_k127_2642555_7 the beta subunit is an iron sulfur cluster containing electron transfer subunit K00371 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 482.0
TLS3_k127_2642555_8 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 482.0
TLS3_k127_2642555_9 Nitrate reductase K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 431.0
TLS3_k127_2646625_0 Alkyl sulfatase dimerisation - - - 1.575e-309 960.0
TLS3_k127_2646625_1 COG2217 Cation transport ATPase - - - 1.731e-250 799.0
TLS3_k127_2646625_10 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 327.0
TLS3_k127_2646625_11 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
TLS3_k127_2646625_12 FR47-like protein - - - 0.000000000000000000000000000000000000000000001759 173.0
TLS3_k127_2646625_13 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000000001693 150.0
TLS3_k127_2646625_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000001371 139.0
TLS3_k127_2646625_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000573 101.0
TLS3_k127_2646625_16 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000009274 100.0
TLS3_k127_2646625_17 Diacylglycerol kinase - - - 0.0000000002907 72.0
TLS3_k127_2646625_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 2.179e-225 710.0
TLS3_k127_2646625_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 512.0
TLS3_k127_2646625_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 443.0
TLS3_k127_2646625_5 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 420.0
TLS3_k127_2646625_6 HAD family hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 394.0
TLS3_k127_2646625_7 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 365.0
TLS3_k127_2646625_8 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 364.0
TLS3_k127_2646625_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 346.0
TLS3_k127_265361_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1167.0
TLS3_k127_265361_1 RNA helicase K06877 - - 6.007e-213 683.0
TLS3_k127_265361_2 SAM-dependent methyltransferase - - - 1.505e-206 654.0
TLS3_k127_265361_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 364.0
TLS3_k127_265361_4 Extradiol ring-cleavage dioxygenase K15777 - - 0.000000000000000000000000000000000001527 139.0
TLS3_k127_265361_5 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000001391 131.0
TLS3_k127_2682638_0 4Fe-4S dicluster domain - - - 2.084e-320 1019.0
TLS3_k127_2682638_1 glutamate:sodium symporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 600.0
TLS3_k127_2682638_10 Protein of unknown function DUF72 - - - 0.000000000000001775 89.0
TLS3_k127_2682638_2 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 451.0
TLS3_k127_2682638_3 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 378.0
TLS3_k127_2682638_4 Enoyl reductase K12445 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005075 282.0
TLS3_k127_2682638_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002068 256.0
TLS3_k127_2682638_6 Protein of unknown function (DUF2587) - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
TLS3_k127_2682638_7 Sucrase/ferredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000002889 209.0
TLS3_k127_2682638_8 metal ion transport - - - 0.00000000000000000000000001243 109.0
TLS3_k127_2682638_9 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.000000000000000000000006653 108.0
TLS3_k127_2698338_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1441.0
TLS3_k127_2698338_1 Domain of unknown function (DUF4173) - - - 1.004e-264 849.0
TLS3_k127_2698338_10 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 440.0
TLS3_k127_2698338_11 Exporter of polyketide K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 454.0
TLS3_k127_2698338_12 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 421.0
TLS3_k127_2698338_13 Uracil permease K03458 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 425.0
TLS3_k127_2698338_14 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 419.0
TLS3_k127_2698338_15 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 354.0
TLS3_k127_2698338_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 312.0
TLS3_k127_2698338_17 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 295.0
TLS3_k127_2698338_18 carbon monoxide dehydrogenase subunit G - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 297.0
TLS3_k127_2698338_19 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 286.0
TLS3_k127_2698338_2 Sugar (and other) transporter K03290,K08178,K08369 - - 2.938e-233 727.0
TLS3_k127_2698338_20 Belongs to the UPF0234 family K09767 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 284.0
TLS3_k127_2698338_21 carbon monoxide dehydrogenase K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
TLS3_k127_2698338_22 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001033 274.0
TLS3_k127_2698338_23 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
TLS3_k127_2698338_24 Belongs to the UPF0336 family - - - 0.000000000000000000000000000000000000000000000000000000000000263 214.0
TLS3_k127_2698338_25 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
TLS3_k127_2698338_26 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000002457 179.0
TLS3_k127_2698338_27 - - - - 0.0000000000000000000000000000000000000006177 153.0
TLS3_k127_2698338_28 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000008422 142.0
TLS3_k127_2698338_29 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000006665 100.0
TLS3_k127_2698338_3 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 1.466e-197 627.0
TLS3_k127_2698338_30 Domain of unknown function (DUF202) - - - 0.000000000000000000004411 101.0
TLS3_k127_2698338_4 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 581.0
TLS3_k127_2698338_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 510.0
TLS3_k127_2698338_6 adenosine deaminase K01488 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 501.0
TLS3_k127_2698338_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 488.0
TLS3_k127_2698338_8 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 474.0
TLS3_k127_2698338_9 Von Willebrand factor K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 458.0
TLS3_k127_2769888_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 7.807e-198 621.0
TLS3_k127_2769888_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 537.0
TLS3_k127_2769888_2 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 450.0
TLS3_k127_2769888_3 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 388.0
TLS3_k127_2769888_4 O-methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 297.0
TLS3_k127_2769888_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 304.0
TLS3_k127_2769888_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
TLS3_k127_2769888_7 - - - - 0.000000000000000000000000000000000000000000000000002234 185.0
TLS3_k127_2769888_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000001496 161.0
TLS3_k127_2863238_0 Alpha-amylase domain K01187 - 3.2.1.20 2.023e-272 848.0
TLS3_k127_2863238_1 Aminotransferase class-III K01845 - 5.4.3.8 1.31e-257 799.0
TLS3_k127_2863238_10 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
TLS3_k127_2863238_11 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 419.0
TLS3_k127_2863238_12 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
TLS3_k127_2863238_13 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 351.0
TLS3_k127_2863238_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 346.0
TLS3_k127_2863238_15 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 330.0
TLS3_k127_2863238_16 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 302.0
TLS3_k127_2863238_17 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 310.0
TLS3_k127_2863238_18 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001732 282.0
TLS3_k127_2863238_19 YqcI/YcgG family K09190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
TLS3_k127_2863238_2 Bacterial protein of unknown function (DUF839) K07093 - - 5.335e-222 697.0
TLS3_k127_2863238_20 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005002 269.0
TLS3_k127_2863238_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001212 261.0
TLS3_k127_2863238_22 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
TLS3_k127_2863238_23 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000003406 174.0
TLS3_k127_2863238_24 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000004001 168.0
TLS3_k127_2863238_25 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000000000000001075 176.0
TLS3_k127_2863238_26 Ornithine cyclodeaminase mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000006627 169.0
TLS3_k127_2863238_27 acetyltransferase K06975 - - 0.0000000000000000000000000000000000001413 145.0
TLS3_k127_2863238_28 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000001759 131.0
TLS3_k127_2863238_29 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000006174 118.0
TLS3_k127_2863238_3 Bacterial extracellular solute-binding protein K10117 - - 1.952e-204 643.0
TLS3_k127_2863238_4 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 2.292e-197 632.0
TLS3_k127_2863238_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 492.0
TLS3_k127_2863238_6 Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 455.0
TLS3_k127_2863238_7 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 452.0
TLS3_k127_2863238_8 Binding-protein-dependent transport systems inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 441.0
TLS3_k127_2863238_9 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 428.0
TLS3_k127_291822_0 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 517.0
TLS3_k127_291822_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 400.0
TLS3_k127_291822_2 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 384.0
TLS3_k127_291822_3 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 290.0
TLS3_k127_291822_4 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000006656 244.0
TLS3_k127_291822_5 Belongs to the WXG100 family - - - 0.000000000000000000000000000004797 135.0
TLS3_k127_291822_6 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000006013 121.0
TLS3_k127_2931762_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1206.0
TLS3_k127_2931762_1 RNA helicase K06877 - - 0.0 1058.0
TLS3_k127_2931762_10 Protein of unknown function (DUF4244) - - - 0.0000001514 57.0
TLS3_k127_2931762_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 371.0
TLS3_k127_2931762_3 type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 339.0
TLS3_k127_2931762_4 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000003864 120.0
TLS3_k127_2931762_5 Secretion system protein - - - 0.00000000000000000002873 100.0
TLS3_k127_2931762_6 - - - - 0.0000000000000000001887 99.0
TLS3_k127_2931762_7 Type ii secretion system K12510 - - 0.000000000002653 77.0
TLS3_k127_2931762_8 - K02282 - - 0.00000000007568 72.0
TLS3_k127_2931762_9 TIGRFAM helicase secretion neighborhood TadE-like protein - - - 0.00000006697 63.0
TLS3_k127_2979712_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1417.0
TLS3_k127_2979712_1 MFS transporter - - - 8.82e-204 661.0
TLS3_k127_2979712_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 425.0
TLS3_k127_2979712_3 C4-dicarboxylate transporter malic acid transport protein K03304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 305.0
TLS3_k127_2979712_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005563 275.0
TLS3_k127_2979712_5 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
TLS3_k127_2979712_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000006357 228.0
TLS3_k127_2979712_7 LppX_LprAFG lipoprotein K14954 - - 0.000000000000000000000000000000000000000000000000000000000007312 221.0
TLS3_k127_2979712_8 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000242 169.0
TLS3_k127_2979712_9 HNH endonuclease - - - 0.000001824 53.0
TLS3_k127_299008_0 Peptidase family M28 - - - 1.023e-216 684.0
TLS3_k127_299008_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.482e-210 682.0
TLS3_k127_299008_10 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
TLS3_k127_299008_11 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
TLS3_k127_299008_12 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000009487 252.0
TLS3_k127_299008_13 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000005489 214.0
TLS3_k127_299008_14 COG1585 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000000000000000000003169 194.0
TLS3_k127_299008_15 phosphoglycerate mutase K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000005288 195.0
TLS3_k127_299008_16 - - - - 0.0000000000000000000000000000000000000000000000005138 189.0
TLS3_k127_299008_17 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000007143 175.0
TLS3_k127_299008_18 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000000000000000003001 174.0
TLS3_k127_299008_19 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000007351 154.0
TLS3_k127_299008_2 Glycosyl transferase family 1 K16148 - 2.4.1.342 5.733e-208 652.0
TLS3_k127_299008_20 - - - - 0.000000000000000008817 89.0
TLS3_k127_299008_21 - - - - 0.00000000000000003315 85.0
TLS3_k127_299008_3 acyl-ACP desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 584.0
TLS3_k127_299008_4 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 553.0
TLS3_k127_299008_5 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 509.0
TLS3_k127_299008_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 486.0
TLS3_k127_299008_7 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 435.0
TLS3_k127_299008_8 RRNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 415.0
TLS3_k127_299008_9 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
TLS3_k127_2991597_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 439.0
TLS3_k127_2991597_1 deoxyhypusine monooxygenase activity K01932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 372.0
TLS3_k127_2991597_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 323.0
TLS3_k127_2991597_3 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000001746 252.0
TLS3_k127_2991597_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000007108 232.0
TLS3_k127_2991597_5 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000003742 143.0
TLS3_k127_2991597_6 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000003124 123.0
TLS3_k127_3002816_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 505.0
TLS3_k127_3002816_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 456.0
TLS3_k127_3002816_10 response regulator K02479,K07684,K07685 - - 0.000000000000000000000000003004 120.0
TLS3_k127_3002816_11 - - - - 0.00000000000000000004371 95.0
TLS3_k127_3002816_13 - - - - 0.000000000002844 67.0
TLS3_k127_3002816_14 deoxyhypusine monooxygenase activity K01932 - - 0.0000000003602 70.0
TLS3_k127_3002816_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 405.0
TLS3_k127_3002816_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 391.0
TLS3_k127_3002816_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 323.0
TLS3_k127_3002816_5 Protein of unknown function (DUF3494) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006583 254.0
TLS3_k127_3002816_6 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000008508 228.0
TLS3_k127_3002816_7 Transcriptional regulator PadR-like family K10947 - - 0.00000000000000000000000000000000000000000000000000001622 189.0
TLS3_k127_3002816_8 Protein of unknown function (DUF1048) - - - 0.000000000000000000000000000000000000000000000001124 177.0
TLS3_k127_3002816_9 Methyltransferase domain - - - 0.00000000000000000000000000004108 131.0
TLS3_k127_3034085_0 COG0474 Cation transport ATPase - - - 9.355e-317 992.0
TLS3_k127_3034085_1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 2.056e-195 616.0
TLS3_k127_3034085_10 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
TLS3_k127_3034085_11 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001197 239.0
TLS3_k127_3034085_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000002809 145.0
TLS3_k127_3034085_13 - - - - 0.000000001176 61.0
TLS3_k127_3034085_2 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 537.0
TLS3_k127_3034085_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 525.0
TLS3_k127_3034085_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 479.0
TLS3_k127_3034085_5 Aminotransferase class v - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 453.0
TLS3_k127_3034085_6 Uncharacterized conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 420.0
TLS3_k127_3034085_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 398.0
TLS3_k127_3034085_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
TLS3_k127_3034085_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 334.0
TLS3_k127_3076560_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 0.0 1512.0
TLS3_k127_3076560_1 Exodeoxyribonuclease V, gamma subunit K03583 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.5 2.036e-313 977.0
TLS3_k127_3076560_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 1.812e-279 877.0
TLS3_k127_3076560_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 480.0
TLS3_k127_3076560_4 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003384 250.0
TLS3_k127_3107678_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848,K11942 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.13,5.4.99.2 0.0 1656.0
TLS3_k127_3107678_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1398.0
TLS3_k127_3107678_10 COG0419 ATPase involved in DNA repair K03546 - - 4.155e-208 683.0
TLS3_k127_3107678_11 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 3.719e-195 614.0
TLS3_k127_3107678_12 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 566.0
TLS3_k127_3107678_13 Lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 528.0
TLS3_k127_3107678_14 chromosome partitioning K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 520.0
TLS3_k127_3107678_15 Transfers the fatty acyl group on membrane lipoproteins K03820 GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 512.0
TLS3_k127_3107678_16 Zn-dependent alcohol dehydrogenase K18012 - 1.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 497.0
TLS3_k127_3107678_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 476.0
TLS3_k127_3107678_18 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 469.0
TLS3_k127_3107678_19 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 447.0
TLS3_k127_3107678_2 Alpha amylase, catalytic domain K05341 - 2.4.1.4 9.215e-303 939.0
TLS3_k127_3107678_20 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 445.0
TLS3_k127_3107678_21 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 441.0
TLS3_k127_3107678_22 Lysine 5,6-aminomutase subunit beta K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 424.0
TLS3_k127_3107678_23 recombinase XerD K04763 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 431.0
TLS3_k127_3107678_24 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 414.0
TLS3_k127_3107678_25 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03212 - 2.1.1.189 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
TLS3_k127_3107678_26 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 376.0
TLS3_k127_3107678_27 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 378.0
TLS3_k127_3107678_28 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 339.0
TLS3_k127_3107678_29 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 315.0
TLS3_k127_3107678_3 Lysine 2,3-aminomutase K01844 - 5.4.3.3 1.885e-295 911.0
TLS3_k127_3107678_30 PFAM NmrA family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 316.0
TLS3_k127_3107678_31 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
TLS3_k127_3107678_32 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 324.0
TLS3_k127_3107678_33 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 303.0
TLS3_k127_3107678_34 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 310.0
TLS3_k127_3107678_35 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 292.0
TLS3_k127_3107678_36 phosphoglycerate mutase K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 293.0
TLS3_k127_3107678_37 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001861 282.0
TLS3_k127_3107678_38 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002874 277.0
TLS3_k127_3107678_39 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000001114 254.0
TLS3_k127_3107678_4 belongs to the CobB CobQ family K13788 - 2.3.1.8 8.182e-279 872.0
TLS3_k127_3107678_40 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001899 240.0
TLS3_k127_3107678_41 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003692 232.0
TLS3_k127_3107678_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009475 244.0
TLS3_k127_3107678_43 3-aminobutyryl-CoA ammonia lyase K18014 - 4.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
TLS3_k127_3107678_44 Signal peptide protein - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
TLS3_k127_3107678_45 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000005502 224.0
TLS3_k127_3107678_46 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000007509 216.0
TLS3_k127_3107678_47 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004251 211.0
TLS3_k127_3107678_48 - - - - 0.000000000000000000000000000000000000000000000000000000001318 224.0
TLS3_k127_3107678_49 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000003413 200.0
TLS3_k127_3107678_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 7.428e-260 809.0
TLS3_k127_3107678_50 PFAM Uncharacterised ACR, COG1259 K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001086 209.0
TLS3_k127_3107678_51 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000000000000000000000005823 198.0
TLS3_k127_3107678_52 MerR family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000007712 195.0
TLS3_k127_3107678_53 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000046 187.0
TLS3_k127_3107678_54 membrane - - - 0.0000000000000000000000000000000000000000000000000009414 187.0
TLS3_k127_3107678_55 - - - - 0.0000000000000000000000000000000000000005371 170.0
TLS3_k127_3107678_56 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.0000000000000000000000000000000000000008467 161.0
TLS3_k127_3107678_57 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000004305 152.0
TLS3_k127_3107678_58 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000000000000001229 155.0
TLS3_k127_3107678_59 - - - - 0.000000000000000000000000000000000203 139.0
TLS3_k127_3107678_6 glutamate--cysteine ligase - - - 4.85e-258 803.0
TLS3_k127_3107678_60 Protein of unknown function (DUF861) K06995 - - 0.0000000000000000000000000000000003092 134.0
TLS3_k127_3107678_61 Acetyltransferase (GNAT) family K06977 - - 0.000000000000000000000000000000004799 136.0
TLS3_k127_3107678_62 Single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000002799 119.0
TLS3_k127_3107678_63 hydrolase K01048 - 3.1.1.5 0.0000000904 54.0
TLS3_k127_3107678_7 Na+/H+ antiporter family - - - 9.169e-228 719.0
TLS3_k127_3107678_8 Histidine--tRNA ligase K01892 - 6.1.1.21 1.03e-227 718.0
TLS3_k127_3107678_9 Major facilitator Superfamily K06902 - - 6.808e-213 671.0
TLS3_k127_313232_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1830.0
TLS3_k127_313232_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1270.0
TLS3_k127_313232_10 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 1.012e-194 616.0
TLS3_k127_313232_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 586.0
TLS3_k127_313232_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 555.0
TLS3_k127_313232_13 Thiamin pyrophosphokinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 518.0
TLS3_k127_313232_14 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 490.0
TLS3_k127_313232_15 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 454.0
TLS3_k127_313232_16 Dihydroorotate oxidase K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 447.0
TLS3_k127_313232_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 417.0
TLS3_k127_313232_18 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 406.0
TLS3_k127_313232_19 Virulence factor MVIN K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 408.0
TLS3_k127_313232_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 0.0 1047.0
TLS3_k127_313232_20 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
TLS3_k127_313232_21 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 363.0
TLS3_k127_313232_22 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 340.0
TLS3_k127_313232_23 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 356.0
TLS3_k127_313232_24 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 325.0
TLS3_k127_313232_25 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 312.0
TLS3_k127_313232_26 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
TLS3_k127_313232_27 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004004 299.0
TLS3_k127_313232_28 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004163 301.0
TLS3_k127_313232_29 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000907 280.0
TLS3_k127_313232_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 2.393e-307 960.0
TLS3_k127_313232_30 Shikimate K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003017 280.0
TLS3_k127_313232_31 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003851 271.0
TLS3_k127_313232_32 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
TLS3_k127_313232_33 ADP-ribose pyrophosphatase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000376 215.0
TLS3_k127_313232_34 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000001712 207.0
TLS3_k127_313232_35 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000002498 207.0
TLS3_k127_313232_36 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002217 199.0
TLS3_k127_313232_37 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000006179 199.0
TLS3_k127_313232_38 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000007759 196.0
TLS3_k127_313232_39 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000005207 184.0
TLS3_k127_313232_4 Phospholipase D. Active site motifs. - - - 1.583e-243 768.0
TLS3_k127_313232_40 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000007305 170.0
TLS3_k127_313232_41 Copper transport outer membrane protein, MctB - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796 - 0.00000000000000000000000000000000000007853 158.0
TLS3_k127_313232_42 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000001005 151.0
TLS3_k127_313232_43 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.00000000000000000000000000000000001363 138.0
TLS3_k127_313232_44 integration host factor - - - 0.00000000000000000000000000000000003698 138.0
TLS3_k127_313232_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 3.676e-226 717.0
TLS3_k127_313232_6 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 6.452e-221 692.0
TLS3_k127_313232_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 2.042e-218 684.0
TLS3_k127_313232_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.672e-206 647.0
TLS3_k127_313232_9 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 4.756e-204 643.0
TLS3_k127_3303260_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.114e-259 805.0
TLS3_k127_3303260_1 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 357.0
TLS3_k127_3303260_2 ABC transporter (Permease) K16927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
TLS3_k127_3303260_3 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 296.0
TLS3_k127_334220_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 1.787e-230 732.0
TLS3_k127_334220_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 608.0
TLS3_k127_334220_2 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
TLS3_k127_334220_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 364.0
TLS3_k127_334220_4 ABC transporter (Permease) K15269 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 304.0
TLS3_k127_334220_5 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.0000000000000000000000000001714 123.0
TLS3_k127_343085_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1692.0
TLS3_k127_343085_1 carbohydrate transport K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 581.0
TLS3_k127_343085_2 DNA topoisomerase K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 490.0
TLS3_k127_343085_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 482.0
TLS3_k127_343085_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.0000000000000000000000000000000000000000001583 161.0
TLS3_k127_34371_0 BCCT, betaine/carnitine/choline family transporter K02168 - - 4.595e-214 678.0
TLS3_k127_34371_1 Phosphate starvation protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 558.0
TLS3_k127_34371_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 520.0
TLS3_k127_34371_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000245 194.0
TLS3_k127_34371_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000001299 186.0
TLS3_k127_34371_5 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000001039 172.0
TLS3_k127_34371_6 HIT domain K02503 - - 0.000000000000000000000000000000000000004668 149.0
TLS3_k127_3441642_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 3.004e-279 872.0
TLS3_k127_3441642_1 AMP-binding enzyme K01897 - 6.2.1.3 4.045e-271 847.0
TLS3_k127_3441642_10 Domain of unknown function (DUF4142) - - - 0.00000000000000000000000000001089 126.0
TLS3_k127_3441642_11 S4 domain K14761 - - 0.00000000000000008231 87.0
TLS3_k127_3441642_2 Cholesterol oxidase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 9.18e-267 859.0
TLS3_k127_3441642_3 Calcineurin-like phosphoesterase - - - 2.552e-235 752.0
TLS3_k127_3441642_4 Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 5.085e-206 644.0
TLS3_k127_3441642_5 part of alternative pathway from alpha-ketoglutarate to succinate K00135 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79 4.283e-199 633.0
TLS3_k127_3441642_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.925e-198 631.0
TLS3_k127_3441642_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 585.0
TLS3_k127_3441642_8 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 534.0
TLS3_k127_3441642_9 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000008638 138.0
TLS3_k127_3443139_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 0.0 1079.0
TLS3_k127_3443139_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 451.0
TLS3_k127_3443139_10 - - - - 0.000000000000000000000000000008777 123.0
TLS3_k127_3443139_11 Reverse transcriptase-like K03469,K22316 - 3.1.26.4,3.1.3.73 0.00000000000000000006071 96.0
TLS3_k127_3443139_12 Bacterial PH domain K09167 - - 0.000000000000000009958 94.0
TLS3_k127_3443139_2 NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 374.0
TLS3_k127_3443139_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 380.0
TLS3_k127_3443139_4 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 357.0
TLS3_k127_3443139_5 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 340.0
TLS3_k127_3443139_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 297.0
TLS3_k127_3443139_7 C4-type zinc ribbon domain K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 289.0
TLS3_k127_3443139_8 Peroxiredoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000005586 215.0
TLS3_k127_3443139_9 Protein of unknown function (DUF3052) - - - 0.0000000000000000000000000000000000000003489 168.0
TLS3_k127_3505349_0 Transcriptional regulator - - - 0.0 1096.0
TLS3_k127_3505349_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1050.0
TLS3_k127_3505349_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 405.0
TLS3_k127_3505349_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 361.0
TLS3_k127_3505349_12 Phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 354.0
TLS3_k127_3505349_13 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 358.0
TLS3_k127_3505349_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 337.0
TLS3_k127_3505349_15 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 322.0
TLS3_k127_3505349_16 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 324.0
TLS3_k127_3505349_17 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 304.0
TLS3_k127_3505349_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000002452 247.0
TLS3_k127_3505349_19 peptidase M22 K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000997 244.0
TLS3_k127_3505349_2 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 1.022e-317 986.0
TLS3_k127_3505349_20 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000002809 233.0
TLS3_k127_3505349_21 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000000000000000000000399 195.0
TLS3_k127_3505349_22 G5 domain protein K21688 - - 0.000000000000000000000000000000000000000000000000000005314 199.0
TLS3_k127_3505349_23 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000000000000000000000000000000000000005255 199.0
TLS3_k127_3505349_24 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000007045 201.0
TLS3_k127_3505349_25 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000001313 179.0
TLS3_k127_3505349_26 DNA synthesis involved in DNA repair - - - 0.00000000000000000000000000000000000000000000001051 181.0
TLS3_k127_3505349_27 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000362 162.0
TLS3_k127_3505349_28 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000008558 173.0
TLS3_k127_3505349_29 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000734 151.0
TLS3_k127_3505349_3 ATP-binding protein K07175 - - 1.44e-248 772.0
TLS3_k127_3505349_30 Domain of unknown function (DUF4307) - - - 0.000000000000002077 89.0
TLS3_k127_3505349_31 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000005485 61.0
TLS3_k127_3505349_32 - - - - 0.0000005024 59.0
TLS3_k127_3505349_4 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 568.0
TLS3_k127_3505349_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 562.0
TLS3_k127_3505349_6 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 499.0
TLS3_k127_3505349_7 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
TLS3_k127_3505349_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 436.0
TLS3_k127_3505349_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 436.0
TLS3_k127_3519895_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 1.196e-280 868.0
TLS3_k127_3519895_1 Class II release factor RF3, C-terminal domain K02837 - - 5.148e-276 861.0
TLS3_k127_3519895_10 Phosphate acyltransferases K00655,K15781 - 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 541.0
TLS3_k127_3519895_11 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 521.0
TLS3_k127_3519895_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 348.0
TLS3_k127_3519895_13 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000147 256.0
TLS3_k127_3519895_14 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001703 252.0
TLS3_k127_3519895_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
TLS3_k127_3519895_16 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000001019 168.0
TLS3_k127_3519895_17 Sterol carrier protein - - - 0.000000000000000000000000000000000000000003566 158.0
TLS3_k127_3519895_18 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000003553 138.0
TLS3_k127_3519895_19 membrane - - - 0.00000000000000000000000000002579 120.0
TLS3_k127_3519895_2 Sulfate permease family K03321 - - 9.041e-267 830.0
TLS3_k127_3519895_20 Protein of unknown function (DUF3073) - - - 0.0000000000000000001575 89.0
TLS3_k127_3519895_22 - - - - 0.0000009179 55.0
TLS3_k127_3519895_23 - - - - 0.0000136 50.0
TLS3_k127_3519895_3 Belongs to the purine-cytosine permease (2.A.39) family K03457 - - 2.267e-254 793.0
TLS3_k127_3519895_4 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 2.796e-240 767.0
TLS3_k127_3519895_5 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 4.852e-235 747.0
TLS3_k127_3519895_6 Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.1.205 2.538e-232 726.0
TLS3_k127_3519895_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 583.0
TLS3_k127_3519895_8 Belongs to the Glu Leu Phe Val dehydrogenases family K00271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 535.0
TLS3_k127_3519895_9 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 577.0
TLS3_k127_3566604_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.0 1715.0
TLS3_k127_3566604_1 Domain of unknown function (DUF3367) - - - 0.0 1361.0
TLS3_k127_3566604_10 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 4.125e-196 613.0
TLS3_k127_3566604_11 May be required for sporulation K09762 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 555.0
TLS3_k127_3566604_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 548.0
TLS3_k127_3566604_13 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 533.0
TLS3_k127_3566604_14 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 520.0
TLS3_k127_3566604_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 490.0
TLS3_k127_3566604_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 462.0
TLS3_k127_3566604_17 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 456.0
TLS3_k127_3566604_18 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 451.0
TLS3_k127_3566604_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 439.0
TLS3_k127_3566604_2 Domain of unknown function (DUF3367) K16648 - - 0.0 1309.0
TLS3_k127_3566604_20 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 436.0
TLS3_k127_3566604_21 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 439.0
TLS3_k127_3566604_22 Branched-chain amino acid transport system / permease component K01997,K11956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 432.0
TLS3_k127_3566604_23 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 418.0
TLS3_k127_3566604_24 Methionine biosynthesis protein MetW K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 407.0
TLS3_k127_3566604_25 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
TLS3_k127_3566604_26 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 400.0
TLS3_k127_3566604_27 membrane K11939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 398.0
TLS3_k127_3566604_28 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 378.0
TLS3_k127_3566604_29 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 381.0
TLS3_k127_3566604_3 Phosphoenolpyruvate carboxylase K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0 1251.0
TLS3_k127_3566604_30 Protein of unknown function (DUF3068) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 366.0
TLS3_k127_3566604_31 Zn-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 339.0
TLS3_k127_3566604_32 SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 326.0
TLS3_k127_3566604_33 Tellurium resistance protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000005774 239.0
TLS3_k127_3566604_34 Tellurium resistance protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000006099 226.0
TLS3_k127_3566604_35 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - - - 0.000000000000000000000000000000000000000000000000000000001873 208.0
TLS3_k127_3566604_36 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000001437 194.0
TLS3_k127_3566604_37 - - - - 0.000000000000000000000000000000000001685 146.0
TLS3_k127_3566604_38 PFAM Rieske 2Fe-2S - - - 0.00000000000000000000000000000000008275 138.0
TLS3_k127_3566604_39 Preprotein translocase subunit SecG K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004607 129.0
TLS3_k127_3566604_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.0 1244.0
TLS3_k127_3566604_40 Domain of unknown function (DUF3806) - - - 0.000000000000000000000008043 106.0
TLS3_k127_3566604_41 - - - - 0.00000000000004402 78.0
TLS3_k127_3566604_42 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000001975 67.0
TLS3_k127_3566604_5 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1091.0
TLS3_k127_3566604_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.528e-301 936.0
TLS3_k127_3566604_7 in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.392e-274 853.0
TLS3_k127_3566604_8 Glucose-6-phosphate isomerase K01810 - 5.3.1.9 2.961e-211 670.0
TLS3_k127_3566604_9 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 1.108e-206 650.0
TLS3_k127_3595034_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575 2.3.1.9 2.332e-223 697.0
TLS3_k127_3595034_1 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 502.0
TLS3_k127_3595034_2 NADPH quinone reductase K17829 - 1.3.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 333.0
TLS3_k127_3595034_3 Thioredoxin K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003257 272.0
TLS3_k127_3595034_4 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006707 255.0
TLS3_k127_3595034_5 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000009372 205.0
TLS3_k127_3595034_6 - - - - 0.0000000000000000000000000000000000000000000000000007627 199.0
TLS3_k127_3595034_7 - - - - 0.00000000000000000000000000001377 126.0
TLS3_k127_3609829_0 Malic enzyme, NAD binding domain K00027,K22212 - 1.1.1.38,4.1.1.101 1.96e-286 889.0
TLS3_k127_3609829_1 LVIVD repeat - - - 2.311e-274 857.0
TLS3_k127_3609829_10 dimethylargininase activity K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000006909 203.0
TLS3_k127_3609829_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000003458 198.0
TLS3_k127_3609829_12 fmn reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000001126 207.0
TLS3_k127_3609829_13 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000004317 172.0
TLS3_k127_3609829_14 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000008194 169.0
TLS3_k127_3609829_15 Histidine kinase - - - 0.000000000000000000001817 107.0
TLS3_k127_3609829_16 Tetratricopeptide repeat - - - 0.000000000000002993 81.0
TLS3_k127_3609829_2 LVIVD repeat - - - 8.012e-231 731.0
TLS3_k127_3609829_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.764e-202 636.0
TLS3_k127_3609829_4 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 573.0
TLS3_k127_3609829_5 Reductase C-terminal K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 573.0
TLS3_k127_3609829_6 Stearoyl-CoA 9-desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 500.0
TLS3_k127_3609829_7 Membrane K03980 GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 486.0
TLS3_k127_3609829_8 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 322.0
TLS3_k127_3609829_9 Peptidase M50B-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
TLS3_k127_3611536_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1346.0
TLS3_k127_3611536_1 Fe-S cluster assembly K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 2.009e-288 887.0
TLS3_k127_3611536_10 Enoyl- acyl-carrier-protein reductase NADH K00208,K11611 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 430.0
TLS3_k127_3611536_11 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 336.0
TLS3_k127_3611536_12 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 277.0
TLS3_k127_3611536_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000002048 219.0
TLS3_k127_3611536_14 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000000000349 228.0
TLS3_k127_3611536_15 metal-sulfur cluster biosynthetic enzyme - - - 0.0000000000000000000000000000000000000000000000000000000126 205.0
TLS3_k127_3611536_16 ferredoxin K05710 - - 0.0000000000000000000000000000000000000000000003119 173.0
TLS3_k127_3611536_17 Protein of unknown function (DUF3099) - - - 0.000000000000000001239 89.0
TLS3_k127_3611536_2 ABC transporter K06147 - - 1.02e-280 876.0
TLS3_k127_3611536_3 ABC transporter K06158 - - 7.564e-280 867.0
TLS3_k127_3611536_4 Tetratrico peptide repeat K03802 - 6.3.2.29,6.3.2.30 9.319e-245 777.0
TLS3_k127_3611536_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 5.31e-196 625.0
TLS3_k127_3611536_6 ABC transporter (Permease) K09015 GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 588.0
TLS3_k127_3611536_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 543.0
TLS3_k127_3611536_8 Iron ABC transporter ATP-binding protein K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 446.0
TLS3_k127_3611536_9 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 433.0
TLS3_k127_3639930_0 von Willebrand factor (vWF) type A domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.015e-319 1006.0
TLS3_k127_3639930_1 Thioredoxin reductase K00384 - 1.8.1.9 2.695e-259 813.0
TLS3_k127_3639930_10 Belongs to the ABC transporter superfamily K02017,K02018 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 371.0
TLS3_k127_3639930_11 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 304.0
TLS3_k127_3639930_12 HAD family hydrolase K01091,K06019 - 3.1.3.18,3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002226 278.0
TLS3_k127_3639930_13 Binding-protein-dependent transport system inner membrane component K02018,K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000005285 231.0
TLS3_k127_3639930_14 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000002351 229.0
TLS3_k127_3639930_15 molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000002281 202.0
TLS3_k127_3639930_16 TOBE domain - - - 0.0000000000000000000000000000000000000000000000000006314 187.0
TLS3_k127_3639930_17 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.00000000000000000000000000000000000000000000007967 183.0
TLS3_k127_3639930_18 transcriptional regulator K03892 - - 0.000000000000000000000000000000000000001214 156.0
TLS3_k127_3639930_19 Protein of unknown function (DUF3263) - - - 0.0000000000000000000000000000000005513 134.0
TLS3_k127_3639930_2 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 4.265e-239 745.0
TLS3_k127_3639930_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 5.693e-197 623.0
TLS3_k127_3639930_4 Sodium Bile acid symporter family K03325,K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 608.0
TLS3_k127_3639930_5 Cysteine desulfurase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 598.0
TLS3_k127_3639930_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 554.0
TLS3_k127_3639930_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K10216 - 3.7.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 408.0
TLS3_k127_3639930_8 G-D-S-L family lipolytic protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 385.0
TLS3_k127_3639930_9 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 380.0
TLS3_k127_3667866_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 520.0
TLS3_k127_3667866_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 495.0
TLS3_k127_3667866_10 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 336.0
TLS3_k127_3667866_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 331.0
TLS3_k127_3667866_12 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 322.0
TLS3_k127_3667866_13 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006078 286.0
TLS3_k127_3667866_14 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007676 270.0
TLS3_k127_3667866_15 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003394 254.0
TLS3_k127_3667866_16 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
TLS3_k127_3667866_17 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000006747 182.0
TLS3_k127_3667866_18 CAAX protease self-immunity - - - 0.00000000000000000000000000000001175 146.0
TLS3_k127_3667866_19 B3/4 domain - - - 0.00000000000000000000000000001734 118.0
TLS3_k127_3667866_2 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 485.0
TLS3_k127_3667866_20 CAAX protease self-immunity K07052 - - 0.000000000000000000000000006529 122.0
TLS3_k127_3667866_21 Polymer-forming cytoskeletal - - - 0.00000000000000000006029 104.0
TLS3_k127_3667866_22 - - - - 0.000000000003005 66.0
TLS3_k127_3667866_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 455.0
TLS3_k127_3667866_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 459.0
TLS3_k127_3667866_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 434.0
TLS3_k127_3667866_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 435.0
TLS3_k127_3667866_7 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 380.0
TLS3_k127_3667866_8 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
TLS3_k127_3667866_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 376.0
TLS3_k127_36754_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1074.0
TLS3_k127_36754_1 Sodium:solute symporter family K14393 - - 1.085e-302 935.0
TLS3_k127_36754_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 334.0
TLS3_k127_36754_11 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 308.0
TLS3_k127_36754_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002589 284.0
TLS3_k127_36754_13 trans-aconitate 2-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000129 282.0
TLS3_k127_36754_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001755 265.0
TLS3_k127_36754_15 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000001514 241.0
TLS3_k127_36754_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000008325 210.0
TLS3_k127_36754_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
TLS3_k127_36754_18 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000007536 194.0
TLS3_k127_36754_19 Sortase family - - - 0.0000000000000000000000000000000000000000000000000007662 190.0
TLS3_k127_36754_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 1.602e-237 762.0
TLS3_k127_36754_20 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000000000004266 171.0
TLS3_k127_36754_21 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000000000000001422 171.0
TLS3_k127_36754_22 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000004056 139.0
TLS3_k127_36754_23 spore germination K03605 - - 0.00000000000000000000000001347 126.0
TLS3_k127_36754_24 - - - - 0.00000000000000000000000719 109.0
TLS3_k127_36754_25 HupF/HypC family K04653,K04656 - - 0.0004861 48.0
TLS3_k127_36754_3 PFAM Nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 6.606e-203 650.0
TLS3_k127_36754_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 3.273e-201 633.0
TLS3_k127_36754_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 485.0
TLS3_k127_36754_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 475.0
TLS3_k127_36754_7 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 457.0
TLS3_k127_36754_8 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 402.0
TLS3_k127_36754_9 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 395.0
TLS3_k127_3771563_0 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0 1232.0
TLS3_k127_3771563_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 4.379e-208 653.0
TLS3_k127_3771563_10 LmbE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 338.0
TLS3_k127_3771563_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008389 229.0
TLS3_k127_3771563_12 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000004451 220.0
TLS3_k127_3771563_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000001491 226.0
TLS3_k127_3771563_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000003094 214.0
TLS3_k127_3771563_15 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000001647 191.0
TLS3_k127_3771563_16 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000004138 166.0
TLS3_k127_3771563_17 PspC domain - - - 0.00000000000000000000000000000000000000001838 171.0
TLS3_k127_3771563_18 - - - - 0.0000000000000000000000000000000000004438 142.0
TLS3_k127_3771563_19 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000007956 111.0
TLS3_k127_3771563_2 ATP-dependent DNA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 588.0
TLS3_k127_3771563_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 518.0
TLS3_k127_3771563_4 PspC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 422.0
TLS3_k127_3771563_5 Alpha/beta-hydrolase family N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 421.0
TLS3_k127_3771563_6 with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 397.0
TLS3_k127_3771563_7 Quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 388.0
TLS3_k127_3771563_8 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 372.0
TLS3_k127_3771563_9 Sugar kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 376.0
TLS3_k127_3786942_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1167.0
TLS3_k127_3786942_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 1.124e-211 667.0
TLS3_k127_3786942_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 1.796e-204 642.0
TLS3_k127_3786942_3 L-threonine 3-dehydrogenase K00060,K08322 - 1.1.1.103,1.1.1.380 1.384e-194 619.0
TLS3_k127_3786942_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 451.0
TLS3_k127_3786942_5 Belongs to the Fur family K22297 - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
TLS3_k127_3786942_6 Psort location Cytoplasmic, score - - - 0.000000000000000004235 89.0
TLS3_k127_3786942_7 Psort location Cytoplasmic, score - - - 0.0000004489 54.0
TLS3_k127_3796847_0 elongation factor G domain IV K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 9.738e-264 830.0
TLS3_k127_3796847_1 Flp pilus assembly protein ATPase CpaF K02283 - - 7.449e-212 664.0
TLS3_k127_3796847_10 Pilus biosynthesis protein TadE - - - 0.000000000000000000000000000000000007174 140.0
TLS3_k127_3796847_11 - - - - 0.000000000000000001246 97.0
TLS3_k127_3796847_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 458.0
TLS3_k127_3796847_3 pilus assembly protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 383.0
TLS3_k127_3796847_4 type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
TLS3_k127_3796847_5 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 327.0
TLS3_k127_3796847_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 327.0
TLS3_k127_3796847_7 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001807 234.0
TLS3_k127_3796847_8 - - - - 0.00000000000000000000000000000000000000000005729 171.0
TLS3_k127_3796847_9 FtsK/SpoIIIE family K03466 - - 0.0000000000000000000000000000000000003349 153.0
TLS3_k127_3873457_0 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 450.0
TLS3_k127_3873457_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004616 252.0
TLS3_k127_3873457_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
TLS3_k127_3873457_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000003198 185.0
TLS3_k127_3873457_4 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000756 177.0
TLS3_k127_3873457_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000001009 158.0
TLS3_k127_3873457_6 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000002042 114.0
TLS3_k127_3873457_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000002925 91.0
TLS3_k127_3882417_0 ATP-dependent helicase K03578 - 3.6.4.13 0.0 1656.0
TLS3_k127_3882417_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 8.528e-213 672.0
TLS3_k127_3882417_10 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 494.0
TLS3_k127_3882417_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 484.0
TLS3_k127_3882417_12 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 504.0
TLS3_k127_3882417_13 Cysteine desulfurase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 481.0
TLS3_k127_3882417_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 451.0
TLS3_k127_3882417_15 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 441.0
TLS3_k127_3882417_16 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 414.0
TLS3_k127_3882417_17 Proteasome assembly chaperone 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 425.0
TLS3_k127_3882417_18 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 362.0
TLS3_k127_3882417_19 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000601 281.0
TLS3_k127_3882417_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.54e-203 649.0
TLS3_k127_3882417_20 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001635 252.0
TLS3_k127_3882417_21 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000006547 252.0
TLS3_k127_3882417_22 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000002489 208.0
TLS3_k127_3882417_23 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001681 185.0
TLS3_k127_3882417_24 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000008915 141.0
TLS3_k127_3882417_25 membrane K02221 - - 0.000000000000000000000000000000005468 133.0
TLS3_k127_3882417_26 DivIVA protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000006901 131.0
TLS3_k127_3882417_27 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000002942 126.0
TLS3_k127_3882417_28 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000001879 129.0
TLS3_k127_3882417_29 - - - - 0.0000000000000000000000000493 122.0
TLS3_k127_3882417_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 8.654e-199 625.0
TLS3_k127_3882417_30 Domain of unknown function (DUF4192) - - - 0.000000000000000000000000274 119.0
TLS3_k127_3882417_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000000000000000000000231 109.0
TLS3_k127_3882417_33 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0001924 46.0
TLS3_k127_3882417_4 cell division protein FtsI K03587 - 3.4.16.4 9.282e-198 638.0
TLS3_k127_3882417_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 610.0
TLS3_k127_3882417_6 DNA polymerase I K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 616.0
TLS3_k127_3882417_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 581.0
TLS3_k127_3882417_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 529.0
TLS3_k127_3882417_9 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 507.0
TLS3_k127_3928708_0 GTP-binding protein TypA K06207 - - 0.0 1078.0
TLS3_k127_3928708_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.781e-237 740.0
TLS3_k127_3928708_10 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 332.0
TLS3_k127_3928708_11 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 298.0
TLS3_k127_3928708_12 heme binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003264 273.0
TLS3_k127_3928708_13 Acetyltransferase K22476 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000006273 256.0
TLS3_k127_3928708_14 ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000048 236.0
TLS3_k127_3928708_15 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000002317 179.0
TLS3_k127_3928708_16 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000002097 147.0
TLS3_k127_3928708_17 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000006853 134.0
TLS3_k127_3928708_18 Protein of unknown function (DUF3117) - - - 0.0000000000000000000000001178 108.0
TLS3_k127_3928708_19 regulation of cell shape - - - 0.000000000007887 73.0
TLS3_k127_3928708_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 584.0
TLS3_k127_3928708_3 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 570.0
TLS3_k127_3928708_4 VanW like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 517.0
TLS3_k127_3928708_5 Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 512.0
TLS3_k127_3928708_6 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 489.0
TLS3_k127_3928708_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 376.0
TLS3_k127_3928708_8 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 361.0
TLS3_k127_3928708_9 phosphoribosyl transferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 351.0
TLS3_k127_3970369_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1117.0
TLS3_k127_3970369_1 acyl-CoA dehydrogenase K09456 - - 1.975e-234 738.0
TLS3_k127_3970369_10 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 419.0
TLS3_k127_3970369_11 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 347.0
TLS3_k127_3970369_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 309.0
TLS3_k127_3970369_13 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 307.0
TLS3_k127_3970369_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 297.0
TLS3_k127_3970369_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001469 235.0
TLS3_k127_3970369_16 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
TLS3_k127_3970369_17 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000003066 228.0
TLS3_k127_3970369_18 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000000000000000000002646 187.0
TLS3_k127_3970369_19 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000174 181.0
TLS3_k127_3970369_2 AAA ATPase domain - - - 6.77e-212 662.0
TLS3_k127_3970369_20 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000317 194.0
TLS3_k127_3970369_21 - - - - 0.0000000000000000000000000000000000000007471 153.0
TLS3_k127_3970369_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000003207 152.0
TLS3_k127_3970369_23 Protein of unknown function (DUF2510) - - - 0.000000000000000000000000005061 123.0
TLS3_k127_3970369_24 - - - - 0.0000000000000000001538 89.0
TLS3_k127_3970369_25 - - - - 0.0001409 46.0
TLS3_k127_3970369_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 2.3.1.9 2.791e-208 653.0
TLS3_k127_3970369_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 626.0
TLS3_k127_3970369_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 605.0
TLS3_k127_3970369_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 599.0
TLS3_k127_3970369_7 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 460.0
TLS3_k127_3970369_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 441.0
TLS3_k127_3970369_9 ABC transporter K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 419.0
TLS3_k127_3982349_0 Sodium:sulfate symporter transmembrane region K14445 - - 2.827e-225 708.0
TLS3_k127_3982349_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 1.554e-221 696.0
TLS3_k127_3982349_2 Folylpolyglutamate synthase K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 1.594e-201 645.0
TLS3_k127_3982349_3 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 416.0
TLS3_k127_3982349_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003732 256.0
TLS3_k127_3982349_5 Protein of unknown function (DUF4233) - - - 0.00000000000000000000000000000000000001347 149.0
TLS3_k127_402047_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1042.0
TLS3_k127_402047_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 545.0
TLS3_k127_402047_10 HIT domain K02503 - - 0.00000000000000000000000000000000000000878 148.0
TLS3_k127_402047_11 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000001246 126.0
TLS3_k127_402047_12 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000001288 123.0
TLS3_k127_402047_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 566.0
TLS3_k127_402047_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 477.0
TLS3_k127_402047_4 Protein of unknown function (DUF3097) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 439.0
TLS3_k127_402047_5 protein tyrosine phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 320.0
TLS3_k127_402047_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008142 281.0
TLS3_k127_402047_7 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000001281 213.0
TLS3_k127_402047_8 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000000000000000000000000000000001016 186.0
TLS3_k127_402047_9 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000008922 169.0
TLS3_k127_4021471_0 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05565,K14086 - - 0.0 1185.0
TLS3_k127_4021471_1 Alpha-galactosidase K07407 - 3.2.1.22 1.816e-289 904.0
TLS3_k127_4021471_10 Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 393.0
TLS3_k127_4021471_11 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 375.0
TLS3_k127_4021471_12 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 323.0
TLS3_k127_4021471_13 Nudix hydrolase K18568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 306.0
TLS3_k127_4021471_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004909 266.0
TLS3_k127_4021471_15 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002326 259.0
TLS3_k127_4021471_16 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
TLS3_k127_4021471_17 GatB YqeY domain-containing protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000008887 208.0
TLS3_k127_4021471_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000000000000000004291 169.0
TLS3_k127_4021471_19 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000000000000000001425 169.0
TLS3_k127_4021471_2 Penicillin-binding Protein - - - 9.502e-220 718.0
TLS3_k127_4021471_20 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000000000003066 162.0
TLS3_k127_4021471_21 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000000000003877 157.0
TLS3_k127_4021471_22 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000000000000005552 143.0
TLS3_k127_4021471_23 - - - - 0.0000000000000000001053 93.0
TLS3_k127_4021471_24 endonuclease - - - 0.0000000000000005472 81.0
TLS3_k127_4021471_25 Multiple resistance and pH regulation protein F (MrpF / PhaF) - - - 0.0000000000001431 74.0
TLS3_k127_4021471_26 DNA integration - - - 0.00000001793 59.0
TLS3_k127_4021471_3 Major Facilitator Superfamily - - - 1.438e-201 640.0
TLS3_k127_4021471_4 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 555.0
TLS3_k127_4021471_5 Proton-conducting membrane transporter K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 558.0
TLS3_k127_4021471_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 524.0
TLS3_k127_4021471_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 428.0
TLS3_k127_4021471_8 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 421.0
TLS3_k127_4021471_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 409.0
TLS3_k127_4037475_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 1.95e-316 975.0
TLS3_k127_4037475_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.528e-250 781.0
TLS3_k127_4037475_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000008459 116.0
TLS3_k127_4037475_11 - - - - 0.0000000000000000000003473 102.0
TLS3_k127_4037475_12 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex - - - 0.000000000000000000008964 94.0
TLS3_k127_4037475_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 550.0
TLS3_k127_4037475_3 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 493.0
TLS3_k127_4037475_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 425.0
TLS3_k127_4037475_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 400.0
TLS3_k127_4037475_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 351.0
TLS3_k127_4037475_7 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
TLS3_k127_4037475_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 312.0
TLS3_k127_4037475_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000125 252.0
TLS3_k127_4203771_0 glycine cleavage system K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 591.0
TLS3_k127_4203771_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 484.0
TLS3_k127_4203771_2 Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.00000000000000000000000000000000000001977 147.0
TLS3_k127_4203771_3 - - - - 0.0000000000000000116 84.0
TLS3_k127_4220081_0 ABC transporter, ATP-binding protein K01990 - - 0.0 1142.0
TLS3_k127_4220081_1 Aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
TLS3_k127_4220081_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000002592 110.0
TLS3_k127_4220081_11 - - - - 0.0000000006841 62.0
TLS3_k127_4220081_2 integral membrane protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 368.0
TLS3_k127_4220081_3 Homocysteine K00547,K21169 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 339.0
TLS3_k127_4220081_4 transferase activity, transferring hexosyl groups - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 304.0
TLS3_k127_4220081_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000009328 211.0
TLS3_k127_4220081_6 Domain of unknown function (DUF1707) - - - 0.0000000000000000000000000000000000000000000000000000001816 216.0
TLS3_k127_4220081_7 Glutaredoxin K18917 - 1.20.4.3 0.0000000000000000000000000000000000000000000000000003867 192.0
TLS3_k127_4220081_8 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000004833 168.0
TLS3_k127_4220903_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 608.0
TLS3_k127_4220903_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 395.0
TLS3_k127_4220903_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 330.0
TLS3_k127_4220903_3 - - - - 0.000000000000000000000000000000000000000000000004594 184.0
TLS3_k127_4220903_4 Septum formation - - - 0.0000000000000000006915 96.0
TLS3_k127_4220903_5 COG3209 Rhs family protein - - - 0.0002771 51.0
TLS3_k127_4223099_0 ABC transporter - - - 1.208e-221 701.0
TLS3_k127_4223099_1 ABC transporter - - - 1.154e-202 645.0
TLS3_k127_4223099_2 ABC transporter, ATP-binding protein - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 382.0
TLS3_k127_4223099_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000001254 160.0
TLS3_k127_4223099_4 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000001539 113.0
TLS3_k127_4223099_5 Single-stranded DNA-binding protein K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000006149 109.0
TLS3_k127_4254029_0 Carboxypeptidase - - - 0.0 1047.0
TLS3_k127_4254029_1 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 3.112e-232 728.0
TLS3_k127_4254029_10 Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 336.0
TLS3_k127_4254029_11 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 315.0
TLS3_k127_4254029_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 307.0
TLS3_k127_4254029_13 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 305.0
TLS3_k127_4254029_14 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
TLS3_k127_4254029_15 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003403 248.0
TLS3_k127_4254029_16 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000015 231.0
TLS3_k127_4254029_17 SprT homologues. - - - 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
TLS3_k127_4254029_18 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
TLS3_k127_4254029_19 - - - - 0.00000000000000000000000000000000000000000000000000000000002094 222.0
TLS3_k127_4254029_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 589.0
TLS3_k127_4254029_20 EcsC protein family - - - 0.00000000000000000000000000000000000000000000000000000001047 211.0
TLS3_k127_4254029_21 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000002576 194.0
TLS3_k127_4254029_22 membrane - - - 0.0000000000000000000000000000000000000000000000003183 179.0
TLS3_k127_4254029_23 - - - - 0.000000000000000000000000000000000008423 143.0
TLS3_k127_4254029_24 - - - - 0.0000000000000000000000000000000000188 143.0
TLS3_k127_4254029_25 HNH endonuclease - - - 0.000000000000000000000002387 105.0
TLS3_k127_4254029_26 - - - - 0.00000000000000000000000491 104.0
TLS3_k127_4254029_27 Transcriptional regulator, MarR family - - - 0.000000002054 65.0
TLS3_k127_4254029_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 589.0
TLS3_k127_4254029_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 554.0
TLS3_k127_4254029_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 545.0
TLS3_k127_4254029_6 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 503.0
TLS3_k127_4254029_7 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 426.0
TLS3_k127_4254029_8 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 380.0
TLS3_k127_4254029_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 392.0
TLS3_k127_425820_0 1,4-alpha-glucan branching enzyme K00700 - 2.4.1.18 3.565e-240 758.0
TLS3_k127_425820_1 glycoside hydrolase family 81 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 413.0
TLS3_k127_425820_2 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000002156 234.0
TLS3_k127_425820_3 PFAM biotin lipoyl attachment domain-containing protein - - - 0.00000000000000000004181 100.0
TLS3_k127_4312980_0 ATP-dependent Clp protease K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 4.735e-293 904.0
TLS3_k127_4312980_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 599.0
TLS3_k127_4312980_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 449.0
TLS3_k127_4312980_3 DNA ligase K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 436.0
TLS3_k127_4312980_4 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 416.0
TLS3_k127_4312980_5 Belongs to the FPG family K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 413.0
TLS3_k127_4312980_6 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 308.0
TLS3_k127_4312980_7 von willebrand factor type a - - - 0.00000000000000000000000000000000000000000004582 185.0
TLS3_k127_4337912_0 Belongs to the DegT DnrJ EryC1 family - - - 2.376e-207 648.0
TLS3_k127_4337912_1 UDP binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 7.284e-204 649.0
TLS3_k127_4337912_10 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 477.0
TLS3_k127_4337912_11 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 460.0
TLS3_k127_4337912_12 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 464.0
TLS3_k127_4337912_13 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 439.0
TLS3_k127_4337912_14 ABC transporter K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 420.0
TLS3_k127_4337912_15 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 420.0
TLS3_k127_4337912_16 ABC-2 type transporter K09692 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 403.0
TLS3_k127_4337912_17 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 398.0
TLS3_k127_4337912_18 Succinyl-CoA 3-ketoacid-CoA transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 353.0
TLS3_k127_4337912_19 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 349.0
TLS3_k127_4337912_2 Glycosyl transferase - - - 1.657e-197 635.0
TLS3_k127_4337912_20 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 338.0
TLS3_k127_4337912_21 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 325.0
TLS3_k127_4337912_22 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
TLS3_k127_4337912_23 SpoIID LytB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001968 298.0
TLS3_k127_4337912_24 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001754 273.0
TLS3_k127_4337912_25 Glycosyl transferase 4-like domain K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002327 268.0
TLS3_k127_4337912_26 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009253 269.0
TLS3_k127_4337912_27 D-glucuronyl C5-epimerase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000005598 258.0
TLS3_k127_4337912_28 - - - - 0.000000000000000000000000000000000000000000000000000001533 196.0
TLS3_k127_4337912_29 Ubiquinone biosynthesis O-methyltransferase - - - 0.000000000000000000000000001283 121.0
TLS3_k127_4337912_3 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 567.0
TLS3_k127_4337912_30 Putative cell wall binding repeat 2 K03641 - - 0.00000000000000001087 98.0
TLS3_k127_4337912_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 574.0
TLS3_k127_4337912_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 550.0
TLS3_k127_4337912_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 536.0
TLS3_k127_4337912_7 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 516.0
TLS3_k127_4337912_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 515.0
TLS3_k127_4337912_9 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 512.0
TLS3_k127_435518_0 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 533.0
TLS3_k127_435518_1 membrane protein terC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 481.0
TLS3_k127_435518_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 291.0
TLS3_k127_435518_3 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000001045 121.0
TLS3_k127_435518_4 - - - - 0.00000000000000000000000000001312 120.0
TLS3_k127_4380959_0 Aldehyde dehydrogenase family - - - 5.661e-253 792.0
TLS3_k127_4380959_1 Pyruvate dehydrogenase E1 K00161,K00166 - 1.2.4.1,1.2.4.4 7.187e-194 612.0
TLS3_k127_4380959_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 529.0
TLS3_k127_4380959_3 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 510.0
TLS3_k127_4380959_4 Von Willebrand factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 317.0
TLS3_k127_4380959_5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000003469 185.0
TLS3_k127_4380959_6 membrane K08972 - - 0.0000000000000000000000000000000000000000002273 177.0
TLS3_k127_4380959_7 - - - - 0.0002769 49.0
TLS3_k127_4402958_0 Major Facilitator Superfamily - - - 6.084e-312 967.0
TLS3_k127_4402958_1 AMP-dependent synthetase K01895 - 6.2.1.1 1.416e-288 893.0
TLS3_k127_4402958_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000001162 140.0
TLS3_k127_4402958_11 AI-2E family transporter - - - 0.00000000000000000000000000000000007783 149.0
TLS3_k127_4402958_12 Plasmid stability protein K21495 - - 0.0000000000000000000000000001737 121.0
TLS3_k127_4402958_13 Sh3 type 3 domain protein - - - 0.00000000000000000000000004507 124.0
TLS3_k127_4402958_2 Alpha amylase, catalytic domain K01176 - 3.2.1.1 2.381e-207 653.0
TLS3_k127_4402958_3 Domain of unknown function DUF87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 511.0
TLS3_k127_4402958_4 transcriptional regulator K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 355.0
TLS3_k127_4402958_5 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 301.0
TLS3_k127_4402958_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000001706 223.0
TLS3_k127_4402958_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000000000000000000000000000000000005895 207.0
TLS3_k127_4402958_8 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000009195 194.0
TLS3_k127_4402958_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000000004888 154.0
TLS3_k127_4412704_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0 1247.0
TLS3_k127_4412704_1 WD40 repeats - - - 1.88e-273 882.0
TLS3_k127_4412704_10 Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated - - - 0.000000000000000000000000000000000000000000000000000000000006142 229.0
TLS3_k127_4412704_2 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 6.72e-219 691.0
TLS3_k127_4412704_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 536.0
TLS3_k127_4412704_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 524.0
TLS3_k127_4412704_5 DUF1704 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 445.0
TLS3_k127_4412704_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 395.0
TLS3_k127_4412704_7 xanthine dehydrogenase accessory protein XdhC K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 382.0
TLS3_k127_4412704_8 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 382.0
TLS3_k127_4412704_9 membrane K08974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 363.0
TLS3_k127_4437378_0 cystathionine gamma-synthase K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 8.29e-210 676.0
TLS3_k127_4437378_1 Glutamate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 527.0
TLS3_k127_4437378_2 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 389.0
TLS3_k127_4437378_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 374.0
TLS3_k127_4437378_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 330.0
TLS3_k127_4437378_5 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000002897 195.0
TLS3_k127_4437378_6 - - - - 0.00000000000001411 78.0
TLS3_k127_4440851_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 6.318e-263 819.0
TLS3_k127_4440851_1 Sodium:alanine symporter family K03310 - - 2.031e-204 657.0
TLS3_k127_4440851_2 impB/mucB/samB family C-terminal domain K02346 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 510.0
TLS3_k127_4440851_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 447.0
TLS3_k127_4440851_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 302.0
TLS3_k127_4440851_5 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 302.0
TLS3_k127_4440851_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
TLS3_k127_4440851_7 AMP binding - - - 0.000000000000000000000000000000000000000000000000006281 184.0
TLS3_k127_4440851_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000001335 190.0
TLS3_k127_4440851_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000007512 55.0
TLS3_k127_4534137_0 DEAD DEAH box helicase - - - 0.0 1490.0
TLS3_k127_4534137_1 unusual protein kinase K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 608.0
TLS3_k127_4534137_10 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000000000000001971 229.0
TLS3_k127_4534137_11 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000001871 196.0
TLS3_k127_4534137_12 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000004542 183.0
TLS3_k127_4534137_13 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000001979 170.0
TLS3_k127_4534137_14 Putative transmembrane protein (PGPGW) - - - 0.000000000000000000000000000000003634 137.0
TLS3_k127_4534137_15 - - - - 0.00000000000000195 84.0
TLS3_k127_4534137_2 Formate/nitrite transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 411.0
TLS3_k127_4534137_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 419.0
TLS3_k127_4534137_4 Chloride transporter K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 406.0
TLS3_k127_4534137_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 401.0
TLS3_k127_4534137_6 Class IV aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 369.0
TLS3_k127_4534137_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 333.0
TLS3_k127_4534137_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004075 275.0
TLS3_k127_4534137_9 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000154 259.0
TLS3_k127_4583046_0 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 1.486e-308 983.0
TLS3_k127_4583046_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.661e-280 866.0
TLS3_k127_4583046_10 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 466.0
TLS3_k127_4583046_11 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 458.0
TLS3_k127_4583046_12 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 442.0
TLS3_k127_4583046_13 Plasmid partitioning protein ParA K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 397.0
TLS3_k127_4583046_14 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 390.0
TLS3_k127_4583046_15 Metal-dependent phosphoesterase K07053,K20859 - 3.1.3.97,3.1.4.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
TLS3_k127_4583046_16 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 353.0
TLS3_k127_4583046_17 LmbE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 320.0
TLS3_k127_4583046_18 Bacterial regulatory helix-turn-helix protein, lysR family K09681 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 322.0
TLS3_k127_4583046_19 Nudix hydrolase K03426 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
TLS3_k127_4583046_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 7.15e-273 853.0
TLS3_k127_4583046_20 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 286.0
TLS3_k127_4583046_21 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005021 259.0
TLS3_k127_4583046_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 239.0
TLS3_k127_4583046_23 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like - - - 0.00000000000000000000000000000000000000000000000000003194 200.0
TLS3_k127_4583046_24 - - - - 0.0000000000000000000000000000000000000000000000005405 188.0
TLS3_k127_4583046_25 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 - - 0.000000000000000000000000000000000004639 147.0
TLS3_k127_4583046_26 transglycosylase associated protein - - - 0.000000000000000000000000000001764 126.0
TLS3_k127_4583046_27 Glutaredoxin K18917 - 1.20.4.3 0.00000000000000000000000001044 113.0
TLS3_k127_4583046_28 ATP-binding protein - - - 0.0000000000000000000009303 98.0
TLS3_k127_4583046_29 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000001207 88.0
TLS3_k127_4583046_3 Belongs to the peptidase M24B family K01262 - 3.4.11.9 2.568e-266 826.0
TLS3_k127_4583046_30 - - - - 0.00000000002391 73.0
TLS3_k127_4583046_4 DNA helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 9.935e-259 817.0
TLS3_k127_4583046_5 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 2.571e-228 719.0
TLS3_k127_4583046_6 Polysaccharide deacetylase - - - 2.7e-199 640.0
TLS3_k127_4583046_7 ABC transporter, ATP-binding protein - - - 6.529e-198 630.0
TLS3_k127_4583046_8 helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 625.0
TLS3_k127_4583046_9 N-terminal half of MaoC dehydratase K14449 - 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 586.0
TLS3_k127_4618528_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 9.334e-307 961.0
TLS3_k127_4618528_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 4.944e-200 639.0
TLS3_k127_4618528_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000005044 58.0
TLS3_k127_4618528_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 573.0
TLS3_k127_4618528_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 362.0
TLS3_k127_4618528_4 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 348.0
TLS3_k127_4618528_5 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 331.0
TLS3_k127_4618528_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000004472 199.0
TLS3_k127_4618528_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000001332 194.0
TLS3_k127_4618528_9 Thioesterase K07107,K12500 - - 0.00000000000000000000000001252 115.0
TLS3_k127_4710093_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1406.0
TLS3_k127_4710093_1 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 0.0 1155.0
TLS3_k127_4710093_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 401.0
TLS3_k127_4710093_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 347.0
TLS3_k127_4710093_12 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 351.0
TLS3_k127_4710093_13 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005845 274.0
TLS3_k127_4710093_14 carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000001501 235.0
TLS3_k127_4710093_15 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000000000000000012 198.0
TLS3_k127_4710093_16 Uncharacterized protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000122 183.0
TLS3_k127_4710093_17 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000009739 157.0
TLS3_k127_4710093_18 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000005474 118.0
TLS3_k127_4710093_19 Protein of unknown function (DUF2877) - - - 0.000000000000000000000000216 116.0
TLS3_k127_4710093_2 Protein of unknown function (DUF1116) - - - 2.094e-249 782.0
TLS3_k127_4710093_20 Protein of unknown function (DUF3017) - - - 0.0000000000002731 76.0
TLS3_k127_4710093_3 Nitrate reductase K02824 - - 9.994e-245 767.0
TLS3_k127_4710093_4 FdrA family K02381 - - 3.246e-204 657.0
TLS3_k127_4710093_5 ATP dependent DNA ligase domain K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 573.0
TLS3_k127_4710093_6 5-oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 558.0
TLS3_k127_4710093_7 transcriptional regulator K09684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 547.0
TLS3_k127_4710093_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 479.0
TLS3_k127_4710093_9 apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 477.0
TLS3_k127_4771527_0 DNA helicase - - - 5.857e-252 790.0
TLS3_k127_4771527_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 6.287e-252 796.0
TLS3_k127_4771527_2 response regulator - - - 0.0000000000000000000000000000000000000000000000005073 186.0
TLS3_k127_4771527_3 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000000000000001002 132.0
TLS3_k127_4771527_4 Family of unknown function (DUF5302) - - - 0.000000000000000002937 87.0
TLS3_k127_4860003_0 RNA nucleotidyltransferase K00970,K00974 - 2.7.7.19,2.7.7.72 7.911e-244 762.0
TLS3_k127_4860003_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 2.44e-208 667.0
TLS3_k127_4860003_10 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000007232 213.0
TLS3_k127_4860003_11 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000009304 169.0
TLS3_k127_4860003_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000003505 139.0
TLS3_k127_4860003_13 Biotin-lipoyl like K02160 - - 0.00000000000000000006367 93.0
TLS3_k127_4860003_2 Penicillin-binding Protein - - - 1.944e-206 668.0
TLS3_k127_4860003_3 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
TLS3_k127_4860003_4 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001219 289.0
TLS3_k127_4860003_5 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002225 269.0
TLS3_k127_4860003_6 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 275.0
TLS3_k127_4860003_7 Serine threonine protein phosphatase K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000004484 260.0
TLS3_k127_4860003_8 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000116 221.0
TLS3_k127_4860003_9 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000001541 216.0
TLS3_k127_4866877_0 phosphomannomutase K01835,K01840 - 5.4.2.2,5.4.2.8 1.263e-252 791.0
TLS3_k127_4866877_1 Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 1.766e-233 731.0
TLS3_k127_4866877_10 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 390.0
TLS3_k127_4866877_11 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 324.0
TLS3_k127_4866877_12 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 305.0
TLS3_k127_4866877_13 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005424 266.0
TLS3_k127_4866877_14 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007107 257.0
TLS3_k127_4866877_15 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000001843 239.0
TLS3_k127_4866877_16 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001616 207.0
TLS3_k127_4866877_17 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000000000001038 158.0
TLS3_k127_4866877_18 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000007932 107.0
TLS3_k127_4866877_2 Exporter of polyketide K01992 - - 1.858e-204 665.0
TLS3_k127_4866877_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 546.0
TLS3_k127_4866877_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 509.0
TLS3_k127_4866877_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 514.0
TLS3_k127_4866877_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 468.0
TLS3_k127_4866877_7 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 452.0
TLS3_k127_4866877_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 444.0
TLS3_k127_4866877_9 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 452.0
TLS3_k127_4897103_0 PA domain - - - 7.057e-315 994.0
TLS3_k127_4897103_1 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 592.0
TLS3_k127_4897103_2 dimethylaminohydrolase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 359.0
TLS3_k127_4897103_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 340.0
TLS3_k127_4897103_4 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 329.0
TLS3_k127_4897103_5 - - - - 0.00000000000000003564 85.0
TLS3_k127_4987952_0 Multicopper oxidase K08100 - 1.3.3.5 4.786e-253 802.0
TLS3_k127_4987952_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 561.0
TLS3_k127_4987952_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 479.0
TLS3_k127_4987952_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 420.0
TLS3_k127_4987952_4 Tryptophanyl-tRNA synthetase K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 0.000000000000000000000000000000000000000000000000000000001415 222.0
TLS3_k127_5021991_0 Heat shock 70 kDa protein K04043 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - 0.0 1073.0
TLS3_k127_5021991_1 ABC transporter, ATP-binding protein K16785,K16786,K16787 - - 9.758e-242 769.0
TLS3_k127_5021991_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
TLS3_k127_5021991_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 372.0
TLS3_k127_5021991_12 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 349.0
TLS3_k127_5021991_13 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 324.0
TLS3_k127_5021991_14 ABC transporter (Permease) K16925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
TLS3_k127_5021991_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002064 262.0
TLS3_k127_5021991_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
TLS3_k127_5021991_17 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000006207 214.0
TLS3_k127_5021991_18 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000007037 212.0
TLS3_k127_5021991_19 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000008231 229.0
TLS3_k127_5021991_2 Multicopper oxidase K06324 - 1.16.3.3 3.898e-223 704.0
TLS3_k127_5021991_20 transcriptional regulator K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000003298 205.0
TLS3_k127_5021991_21 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000285 198.0
TLS3_k127_5021991_22 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000001148 194.0
TLS3_k127_5021991_23 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001158 160.0
TLS3_k127_5021991_24 Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.0000000000000000000000000000000000000001678 154.0
TLS3_k127_5021991_25 Sap, sulfolipid-1-addressing protein - - - 0.000000000000000000000000000000000000001169 155.0
TLS3_k127_5021991_26 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.000000000000000000000000000000000000001795 147.0
TLS3_k127_5021991_27 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000005717 152.0
TLS3_k127_5021991_28 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000001993 145.0
TLS3_k127_5021991_29 - - - - 0.000000000000000000000000006265 115.0
TLS3_k127_5021991_3 MFS transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 495.0
TLS3_k127_5021991_30 Protein of unknown function (DUF4235) - - - 0.00000000000000000000000002027 116.0
TLS3_k127_5021991_31 sigma 54 modulation protein ribosomal protein S30EA - - - 0.000000000000000000001333 99.0
TLS3_k127_5021991_32 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000001464 73.0
TLS3_k127_5021991_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 488.0
TLS3_k127_5021991_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 487.0
TLS3_k127_5021991_6 molecular chaperone K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 479.0
TLS3_k127_5021991_7 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 469.0
TLS3_k127_5021991_8 Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 442.0
TLS3_k127_5021991_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 394.0
TLS3_k127_5038298_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 8.04e-300 927.0
TLS3_k127_5038298_1 Peptidase dimerisation domain - - - 6.642e-207 652.0
TLS3_k127_5038298_10 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 282.0
TLS3_k127_5038298_11 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006915 265.0
TLS3_k127_5038298_12 Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000000000000000000000000000000000000003467 199.0
TLS3_k127_5038298_13 - - - - 0.000000000000000000000000000000001334 136.0
TLS3_k127_5038298_14 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000001405 132.0
TLS3_k127_5038298_15 - - - - 0.00000000000000002085 83.0
TLS3_k127_5038298_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 5.169e-201 628.0
TLS3_k127_5038298_3 Dehydrogenase K00382 - 1.8.1.4 4.198e-195 619.0
TLS3_k127_5038298_4 glycine cleavage system K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 589.0
TLS3_k127_5038298_5 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 583.0
TLS3_k127_5038298_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 531.0
TLS3_k127_5038298_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 366.0
TLS3_k127_5038298_8 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 378.0
TLS3_k127_5038298_9 epimerase K07071 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 335.0
TLS3_k127_5128487_0 Type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.331e-290 899.0
TLS3_k127_5128487_1 homogentisate 12-dioxygenase K00451 - 1.13.11.5 1.386e-239 746.0
TLS3_k127_5128487_10 Domain of unknown function (DUF2017) - - - 0.000000000000000000000000000000000000000000192 168.0
TLS3_k127_5128487_11 - - - - 0.00000000000000000000000000000000000001453 162.0
TLS3_k127_5128487_12 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000004082 111.0
TLS3_k127_5128487_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000839 93.0
TLS3_k127_5128487_14 - - - - 0.000000000104 68.0
TLS3_k127_5128487_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 5.979e-237 737.0
TLS3_k127_5128487_3 Fumarylacetoacetase K01555 - 3.7.1.2 8.082e-213 693.0
TLS3_k127_5128487_4 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 431.0
TLS3_k127_5128487_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 339.0
TLS3_k127_5128487_6 AsnC family transcriptional regulator K03718 - - 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
TLS3_k127_5128487_7 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000004926 218.0
TLS3_k127_5128487_8 Protein of unknown function (DUF2510) - - - 0.000000000000000000000000000000000000000000000001248 185.0
TLS3_k127_5128487_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000008235 161.0
TLS3_k127_5134534_0 SNF2 family N-terminal domain - - - 0.0 1053.0
TLS3_k127_5134534_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 320.0
TLS3_k127_5134534_2 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000009375 221.0
TLS3_k127_5134534_3 - - - - 0.00000000000000000000000000000000000009932 152.0
TLS3_k127_5134534_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000001938 79.0
TLS3_k127_5194061_0 B12 binding domain K00548 - 2.1.1.13 0.0 1804.0
TLS3_k127_5194061_1 RNA helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1293.0
TLS3_k127_5194061_10 Carboxylate--amine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 442.0
TLS3_k127_5194061_11 Protein of unknown function (DUF3866) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 434.0
TLS3_k127_5194061_12 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 402.0
TLS3_k127_5194061_13 Domain of unknown function DUF83 K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 391.0
TLS3_k127_5194061_14 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 406.0
TLS3_k127_5194061_15 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 385.0
TLS3_k127_5194061_16 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 368.0
TLS3_k127_5194061_17 Diacylglycerol kinase K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
TLS3_k127_5194061_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 303.0
TLS3_k127_5194061_19 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002868 283.0
TLS3_k127_5194061_2 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 3.563e-295 912.0
TLS3_k127_5194061_20 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000459 271.0
TLS3_k127_5194061_21 PFAM Phosphatidylinositol 3- and 4-kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
TLS3_k127_5194061_22 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005408 264.0
TLS3_k127_5194061_23 Cellulose-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002549 241.0
TLS3_k127_5194061_24 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
TLS3_k127_5194061_25 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
TLS3_k127_5194061_26 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000004958 212.0
TLS3_k127_5194061_27 Membrane - - - 0.00000000000000000001558 106.0
TLS3_k127_5194061_28 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000112 89.0
TLS3_k127_5194061_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000009679 86.0
TLS3_k127_5194061_3 Pup deamidase depupylase K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 2.483e-236 739.0
TLS3_k127_5194061_30 Protein of unknown function (DUF3090) - - - 0.0000000000000008131 77.0
TLS3_k127_5194061_4 Lysine 2,3-aminomutase K01843 - 5.4.3.2 4.879e-225 699.0
TLS3_k127_5194061_5 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 7.924e-224 701.0
TLS3_k127_5194061_6 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 557.0
TLS3_k127_5194061_7 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 531.0
TLS3_k127_5194061_8 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 508.0
TLS3_k127_5194061_9 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 449.0
TLS3_k127_5235489_0 ABC transporter, ATP-binding protein - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1046.0
TLS3_k127_5235489_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.364e-295 911.0
TLS3_k127_5235489_2 acyl-CoA dehydrogenase K00249,K00255 - 1.3.8.7,1.3.8.8 4.097e-214 685.0
TLS3_k127_5235489_3 Bacterial transcriptional activator domain - - - 5.19e-214 715.0
TLS3_k127_5235489_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 562.0
TLS3_k127_5235489_5 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 408.0
TLS3_k127_5235489_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 320.0
TLS3_k127_5235489_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000007654 223.0
TLS3_k127_5235489_8 single-stranded DNA-binding protein K03111 - - 0.000000001333 64.0
TLS3_k127_5236010_0 part of alternative pathway from alpha-ketoglutarate to succinate K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1988.0
TLS3_k127_5236010_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 1.103e-199 631.0
TLS3_k127_5236010_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001474 262.0
TLS3_k127_5236010_11 Ferritin-like domain K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
TLS3_k127_5236010_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005276 260.0
TLS3_k127_5236010_13 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002556 234.0
TLS3_k127_5236010_14 DoxX family - - - 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
TLS3_k127_5236010_15 G-D-S-L family lipolytic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000894 222.0
TLS3_k127_5236010_16 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000000000000001205 179.0
TLS3_k127_5236010_17 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000001402 151.0
TLS3_k127_5236010_18 - - - - 0.00000000000000000000001005 107.0
TLS3_k127_5236010_19 Peptidase S24-like - - - 0.00000000000000000001508 98.0
TLS3_k127_5236010_2 Malate dehydrogenase K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 591.0
TLS3_k127_5236010_20 Putative zinc-finger - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000006281 90.0
TLS3_k127_5236010_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 576.0
TLS3_k127_5236010_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 574.0
TLS3_k127_5236010_5 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
TLS3_k127_5236010_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 439.0
TLS3_k127_5236010_7 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 411.0
TLS3_k127_5236010_8 Peptide ABC transporter permease K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 386.0
TLS3_k127_5236010_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
TLS3_k127_524756_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 1.96e-309 960.0
TLS3_k127_524756_1 Transposase - - - 4.693e-197 621.0
TLS3_k127_524756_2 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 468.0
TLS3_k127_524756_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
TLS3_k127_524756_4 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000002755 229.0
TLS3_k127_524756_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000002549 186.0
TLS3_k127_524756_6 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000000000000000000000001227 179.0
TLS3_k127_524756_7 Bacterial transcriptional activator domain - - - 0.00000000002864 72.0
TLS3_k127_524756_8 Sigma-70 region 2 K03088 - - 0.000001076 56.0
TLS3_k127_5255069_0 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
TLS3_k127_5255069_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 381.0
TLS3_k127_5255069_2 Multidrug ABC transporter ATPase K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
TLS3_k127_5255069_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 269.0
TLS3_k127_5255069_4 ABC transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008551 269.0
TLS3_k127_5255069_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000006039 254.0
TLS3_k127_5255069_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000003328 174.0
TLS3_k127_5255069_7 Fe-S cluster assembly K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.000000000000000000000000000000000003856 144.0
TLS3_k127_5273637_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 9.005e-285 884.0
TLS3_k127_5273637_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 1.322e-200 631.0
TLS3_k127_5273637_10 Deoxyribose-phosphate aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 388.0
TLS3_k127_5273637_11 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 359.0
TLS3_k127_5273637_12 GntR family transcriptional regulator K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 350.0
TLS3_k127_5273637_13 5-deoxyglucuronate isomerase K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 367.0
TLS3_k127_5273637_14 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 342.0
TLS3_k127_5273637_15 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
TLS3_k127_5273637_16 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004873 264.0
TLS3_k127_5273637_17 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
TLS3_k127_5273637_18 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000002061 171.0
TLS3_k127_5273637_2 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 574.0
TLS3_k127_5273637_3 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 541.0
TLS3_k127_5273637_4 Xylose isomerase-like TIM barrel K06605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 486.0
TLS3_k127_5273637_5 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 477.0
TLS3_k127_5273637_6 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 449.0
TLS3_k127_5273637_7 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 434.0
TLS3_k127_5273637_8 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 422.0
TLS3_k127_5273637_9 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 401.0
TLS3_k127_5314891_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.479e-195 623.0
TLS3_k127_5314891_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 640.0
TLS3_k127_5314891_10 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 415.0
TLS3_k127_5314891_11 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 391.0
TLS3_k127_5314891_12 Potassium K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 318.0
TLS3_k127_5314891_13 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 295.0
TLS3_k127_5314891_14 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 271.0
TLS3_k127_5314891_15 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005974 244.0
TLS3_k127_5314891_16 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002828 261.0
TLS3_k127_5314891_17 N-acetyltransferase GCN5 - - - 0.00000000000000000000000000000000000000000000000000000000000008734 225.0
TLS3_k127_5314891_18 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001484 149.0
TLS3_k127_5314891_2 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 556.0
TLS3_k127_5314891_3 ATP-dependent Clp protease K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 482.0
TLS3_k127_5314891_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 454.0
TLS3_k127_5314891_5 acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 446.0
TLS3_k127_5314891_6 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 451.0
TLS3_k127_5314891_7 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 415.0
TLS3_k127_5314891_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 409.0
TLS3_k127_5314891_9 Adenine glycosylase K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 412.0
TLS3_k127_5390139_0 carboxylase K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0 1006.0
TLS3_k127_5390139_1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.879e-218 690.0
TLS3_k127_5390139_10 GDYXXLXY protein - - - 0.0000000000000000000000000000000000000000003844 166.0
TLS3_k127_5390139_11 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000001044 83.0
TLS3_k127_5390139_12 - - - - 0.000000006133 63.0
TLS3_k127_5390139_2 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 4.22e-214 670.0
TLS3_k127_5390139_3 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 521.0
TLS3_k127_5390139_4 Peptidase family S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 507.0
TLS3_k127_5390139_5 Peptidase, S10 (Carboxypeptidase Y) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 466.0
TLS3_k127_5390139_6 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 441.0
TLS3_k127_5390139_7 Aldo/keto reductase family K06221 - 1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 382.0
TLS3_k127_5390139_8 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 300.0
TLS3_k127_5390139_9 MerR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001616 216.0
TLS3_k127_5398718_0 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 6.323e-213 663.0
TLS3_k127_5398718_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 580.0
TLS3_k127_5398718_10 Na H antiporter - - - 0.00000000000000000000000000000000000000000000004025 188.0
TLS3_k127_5398718_11 - - - - 0.000000000000000000000000000000000000000000001314 171.0
TLS3_k127_5398718_12 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000005904 163.0
TLS3_k127_5398718_13 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000001183 150.0
TLS3_k127_5398718_14 Belongs to the P(II) protein family - - - 0.000000000000000000000000000001259 135.0
TLS3_k127_5398718_15 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000005792 101.0
TLS3_k127_5398718_16 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000001935 94.0
TLS3_k127_5398718_17 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000001886 79.0
TLS3_k127_5398718_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 528.0
TLS3_k127_5398718_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 462.0
TLS3_k127_5398718_4 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 419.0
TLS3_k127_5398718_5 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 400.0
TLS3_k127_5398718_6 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 391.0
TLS3_k127_5398718_7 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 364.0
TLS3_k127_5398718_8 Peptidoglycan-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 289.0
TLS3_k127_5398718_9 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009287 251.0
TLS3_k127_5500418_0 Belongs to the transketolase family K00615 - 2.2.1.1 3.328e-319 992.0
TLS3_k127_5500418_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 449.0
TLS3_k127_5500418_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 368.0
TLS3_k127_5500418_3 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
TLS3_k127_5500418_4 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000296 285.0
TLS3_k127_5500418_5 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.000000000000000000000000000000000000000000000000000000000000003792 218.0
TLS3_k127_5500418_6 HNH nucleases - - - 0.0000000000737 66.0
TLS3_k127_5513364_0 Domain of unknown function (DUF3390) K18929 - - 3.912e-261 820.0
TLS3_k127_5513364_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895 - 2.7.1.90 1.297e-229 714.0
TLS3_k127_5513364_2 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 557.0
TLS3_k127_5513364_3 Fe-S osidoreductase K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
TLS3_k127_5513364_4 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 407.0
TLS3_k127_5513364_5 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
TLS3_k127_5513364_6 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000001359 188.0
TLS3_k127_5513364_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000001083 156.0
TLS3_k127_5513364_8 Domain of unknown function (DUF4142) - - - 0.0000000000000000000000000000000000008235 162.0
TLS3_k127_5513364_9 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007,K21787 - 2.7.9.2 0.00000000001934 68.0
TLS3_k127_5573021_0 Belongs to the TPP enzyme family - - - 0.0 1037.0
TLS3_k127_5573021_1 ABC transporter transmembrane region K06147 - - 7.783e-213 676.0
TLS3_k127_5573021_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 519.0
TLS3_k127_5573021_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 459.0
TLS3_k127_5573021_4 Inosose dehydratase K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 448.0
TLS3_k127_5573021_5 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 421.0
TLS3_k127_5573021_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 406.0
TLS3_k127_5573021_7 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 318.0
TLS3_k127_5573021_8 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000615 228.0
TLS3_k127_5573021_9 Phosphotransferase enzyme family - - - 0.000000000000000000000000001315 128.0
TLS3_k127_5614426_0 Phosphotransferase system, EIIC K02802,K02803,K02804 - 2.7.1.193 0.0 1027.0
TLS3_k127_5614426_1 Transporter associated domain - - - 8.056e-215 676.0
TLS3_k127_5614426_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 430.0
TLS3_k127_5614426_11 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564,K02804 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 411.0
TLS3_k127_5614426_12 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 407.0
TLS3_k127_5614426_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 413.0
TLS3_k127_5614426_14 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 408.0
TLS3_k127_5614426_15 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 404.0
TLS3_k127_5614426_16 Glutaminase K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 390.0
TLS3_k127_5614426_17 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 381.0
TLS3_k127_5614426_18 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 350.0
TLS3_k127_5614426_19 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 349.0
TLS3_k127_5614426_2 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 572.0
TLS3_k127_5614426_20 homocysteine K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 334.0
TLS3_k127_5614426_21 Glycosyltransferase, MGT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002232 293.0
TLS3_k127_5614426_22 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003367 313.0
TLS3_k127_5614426_23 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000222 265.0
TLS3_k127_5614426_24 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
TLS3_k127_5614426_25 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 253.0
TLS3_k127_5614426_26 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
TLS3_k127_5614426_27 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000006359 256.0
TLS3_k127_5614426_28 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
TLS3_k127_5614426_29 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000003352 223.0
TLS3_k127_5614426_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 561.0
TLS3_k127_5614426_30 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000000009 200.0
TLS3_k127_5614426_31 - - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000003342 185.0
TLS3_k127_5614426_32 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000001334 181.0
TLS3_k127_5614426_33 RDD family - - - 0.0000000000000000000000000000000009834 140.0
TLS3_k127_5614426_34 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000001539 137.0
TLS3_k127_5614426_35 - - - - 0.00000000000000000000000000001829 125.0
TLS3_k127_5614426_36 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000005319 126.0
TLS3_k127_5614426_37 2'-5' RNA ligase superfamily - - - 0.00000000000000000000001878 107.0
TLS3_k127_5614426_38 Ion channel - - - 0.0000000000000000000004443 104.0
TLS3_k127_5614426_39 GAF domain - - - 0.0000000000000000007096 93.0
TLS3_k127_5614426_4 Rhodanese Homology Domain K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 505.0
TLS3_k127_5614426_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 474.0
TLS3_k127_5614426_6 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 478.0
TLS3_k127_5614426_7 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 465.0
TLS3_k127_5614426_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 456.0
TLS3_k127_5614426_9 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 449.0
TLS3_k127_57039_0 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 3.598e-223 702.0
TLS3_k127_57039_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.468e-218 685.0
TLS3_k127_57039_2 D-arabinono-1,4-lactone oxidase K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 485.0
TLS3_k127_57039_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 422.0
TLS3_k127_57039_4 Bacterial PH domain - - - 0.000000000000000000000001576 114.0
TLS3_k127_57039_5 - - - - 0.00000000000005641 81.0
TLS3_k127_5890140_0 PTS system mannitol-specific K02798,K02799,K02800 - 2.7.1.197 2.276e-295 919.0
TLS3_k127_5890140_1 Peptide ABC transporter substrate-binding protein K15580 - - 3.377e-222 703.0
TLS3_k127_5890140_2 NADH dehydrogenase K03885 - 1.6.99.3 8.604e-212 669.0
TLS3_k127_5890140_3 alcohol dehydrogenase K00008 - 1.1.1.14 3.965e-203 636.0
TLS3_k127_5890140_4 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 591.0
TLS3_k127_5890140_5 protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 517.0
TLS3_k127_5890140_6 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 394.0
TLS3_k127_5890140_7 PFAM amino acid permease-associated region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 389.0
TLS3_k127_5890140_8 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000009349 136.0
TLS3_k127_5890140_9 - - - - 0.0000003626 54.0
TLS3_k127_5986270_0 Domain of unknown function (DUF1727) - - - 2.545e-194 621.0
TLS3_k127_5986270_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 609.0
TLS3_k127_5986270_2 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 471.0
TLS3_k127_5986270_3 CobB/CobQ-like glutamine amidotransferase domain K07009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 365.0
TLS3_k127_5986270_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 305.0
TLS3_k127_5986270_5 - - - - 0.0000004588 55.0
TLS3_k127_6032630_0 Glycosyltransferase Family 4 K15521 - 2.4.1.250 3.018e-235 746.0
TLS3_k127_6032630_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 3.404e-214 674.0
TLS3_k127_6032630_10 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000004745 140.0
TLS3_k127_6032630_11 Epimerase dehydratase - - - 0.000000000000000000000000000000000008642 146.0
TLS3_k127_6032630_12 - - - - 0.00000000000000000000000000000001775 130.0
TLS3_k127_6032630_13 - - - - 0.00000000000000000000000000000002803 147.0
TLS3_k127_6032630_14 Cholesterol oxidase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.000000000000000000002071 108.0
TLS3_k127_6032630_17 uridine kinase K00876 - 2.7.1.48 0.0000000191 60.0
TLS3_k127_6032630_18 HNH nucleases - - - 0.0000000291 61.0
TLS3_k127_6032630_19 uridine kinase K00876 - 2.7.1.48 0.0001413 51.0
TLS3_k127_6032630_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 3.924e-211 662.0
TLS3_k127_6032630_3 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 483.0
TLS3_k127_6032630_4 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 445.0
TLS3_k127_6032630_5 UPF0060 membrane protein K09771 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000009019 205.0
TLS3_k127_6032630_6 GXWXG protein - - - 0.00000000000000000000000000000000000000000000000000002406 208.0
TLS3_k127_6032630_7 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000001674 194.0
TLS3_k127_6032630_8 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000001525 160.0
TLS3_k127_6032630_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000002711 147.0
TLS3_k127_6033406_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 422.0
TLS3_k127_6033406_10 ankyrin repeats - - - 0.0000000000000000000000000000000000000002437 162.0
TLS3_k127_6033406_11 AAA ATPase domain - - - 0.00000000000000000000000000000000001072 142.0
TLS3_k127_6033406_12 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000001483 116.0
TLS3_k127_6033406_13 GYD domain - - - 0.00000000000000000000004034 112.0
TLS3_k127_6033406_14 - - - - 0.000000000000000000001719 107.0
TLS3_k127_6033406_15 Cupin domain - - - 0.000000000000000000004512 99.0
TLS3_k127_6033406_16 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000105 89.0
TLS3_k127_6033406_17 Bacterial regulatory proteins, tetR family - - - 0.0000000000005127 77.0
TLS3_k127_6033406_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
TLS3_k127_6033406_3 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 391.0
TLS3_k127_6033406_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 319.0
TLS3_k127_6033406_5 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000002736 221.0
TLS3_k127_6033406_6 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000005593 210.0
TLS3_k127_6033406_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001105 211.0
TLS3_k127_6033406_8 - - - - 0.000000000000000000000000000000000000000000000005187 175.0
TLS3_k127_6033406_9 Glycosyltransferase, MGT family - - - 0.00000000000000000000000000000000000000000000001238 189.0
TLS3_k127_6033842_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.486e-216 682.0
TLS3_k127_6033842_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 2.377e-201 638.0
TLS3_k127_6033842_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 514.0
TLS3_k127_6033842_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 488.0
TLS3_k127_6033842_4 Polyprenyl synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 368.0
TLS3_k127_6033842_5 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 352.0
TLS3_k127_6033842_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 339.0
TLS3_k127_6033842_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003001 261.0
TLS3_k127_6033842_9 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000002373 121.0
TLS3_k127_6045860_0 DNA helicase - - - 0.0 1352.0
TLS3_k127_6045860_1 nuclease - - - 0.0 1241.0
TLS3_k127_6045860_10 molybdopterin K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 430.0
TLS3_k127_6045860_11 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 402.0
TLS3_k127_6045860_12 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 387.0
TLS3_k127_6045860_13 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 386.0
TLS3_k127_6045860_14 membrane K20469 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 361.0
TLS3_k127_6045860_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 302.0
TLS3_k127_6045860_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001656 289.0
TLS3_k127_6045860_17 Molybdenum cofactor biosynthesis protein MoaC K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000002652 247.0
TLS3_k127_6045860_18 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
TLS3_k127_6045860_19 Molybdenum cofactor synthesis protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000001914 213.0
TLS3_k127_6045860_2 penicillin amidase K01434 - 3.5.1.11 1.077e-321 1005.0
TLS3_k127_6045860_20 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000000000000004924 205.0
TLS3_k127_6045860_21 N-acetyltransferase GCN5 K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000005718 211.0
TLS3_k127_6045860_22 Fic/DOC family K07341 - - 0.0000000000000000000000000000000000000000000000000000000008626 203.0
TLS3_k127_6045860_23 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000002412 210.0
TLS3_k127_6045860_24 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000003065 222.0
TLS3_k127_6045860_25 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000002831 196.0
TLS3_k127_6045860_26 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000003075 210.0
TLS3_k127_6045860_27 Polysaccharide deacetylase K01181,K22278 - 3.2.1.8,3.5.1.104 0.000000000000000000000000000000000000000000000005114 179.0
TLS3_k127_6045860_28 Cupin domain - - - 0.00000000000000000000000000000000000000000000003218 175.0
TLS3_k127_6045860_29 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.000000000000000000000000000000000000000006661 165.0
TLS3_k127_6045860_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0050896,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 6.061e-225 711.0
TLS3_k127_6045860_30 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000001932 160.0
TLS3_k127_6045860_31 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000002225 154.0
TLS3_k127_6045860_32 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000000000000000000000000004763 146.0
TLS3_k127_6045860_33 mechanosensitive channel K03282 - - 0.00000000000000000000000000000000000008161 148.0
TLS3_k127_6045860_34 - - - - 0.0000000000000000000000000000000000005251 153.0
TLS3_k127_6045860_35 Nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000009402 126.0
TLS3_k127_6045860_36 CopG domain protein DNA-binding domain protein K18918 - - 0.000000000000000000000000000003046 121.0
TLS3_k127_6045860_37 Putative regulatory protein - - - 0.0000000000000000000000000002346 119.0
TLS3_k127_6045860_38 Protein of unknown function DUF86 - - - 0.000000000000000000000000002603 118.0
TLS3_k127_6045860_39 YCII-related domain - - - 0.000000000000000000000000158 108.0
TLS3_k127_6045860_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 563.0
TLS3_k127_6045860_40 - - - - 0.00000000000000000000001729 109.0
TLS3_k127_6045860_41 - - - - 0.0000000000000000000399 96.0
TLS3_k127_6045860_42 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000006161 97.0
TLS3_k127_6045860_43 Nucleotidyltransferase domain K07075 - - 0.00000000000000000008989 91.0
TLS3_k127_6045860_44 addiction module antidote protein, CC2985 family - GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.00000000000000001126 84.0
TLS3_k127_6045860_45 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000002811 61.0
TLS3_k127_6045860_46 Belongs to the 'phage' integrase family - - - 0.0008282 42.0
TLS3_k127_6045860_5 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 545.0
TLS3_k127_6045860_6 Potassium transporter CPA K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 551.0
TLS3_k127_6045860_7 NADPH quinone K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 504.0
TLS3_k127_6045860_8 ERCC4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 451.0
TLS3_k127_6045860_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 473.0
TLS3_k127_6048176_0 Catalyzes two discrete reactions in the de novo synthesis of purines the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide K01756 - 4.3.2.2 7.004e-263 817.0
TLS3_k127_6048176_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 469.0
TLS3_k127_6048176_2 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 385.0
TLS3_k127_6048176_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000007636 253.0
TLS3_k127_6048176_4 Putative cell wall binding repeat 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000153 254.0
TLS3_k127_6048176_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000007507 218.0
TLS3_k127_6048176_6 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000000001852 196.0
TLS3_k127_6048176_7 ABC transporter, ATP-binding protein K06148,K16012 - - 0.00000000000000000000000000000000000000000000000001525 184.0
TLS3_k127_6048176_8 Transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000509 152.0
TLS3_k127_6091169_0 Belongs to the major facilitator superfamily K07001 - - 2.291e-291 929.0
TLS3_k127_6091169_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 3.298e-210 668.0
TLS3_k127_6091169_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000007936 189.0
TLS3_k127_6091169_11 Response regulator receiver domain protein - - - 0.0000000000000000000000000000000000000000000000000006533 203.0
TLS3_k127_6091169_12 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000002431 174.0
TLS3_k127_6091169_13 cyclic nucleotide binding - - - 0.0000000000000000000000000000000000000000000472 167.0
TLS3_k127_6091169_14 Redoxin - - - 0.00000000000000000000000000000000164 138.0
TLS3_k127_6091169_15 Putative zinc-finger - - - 0.000000000000000000000000000001111 132.0
TLS3_k127_6091169_16 Belongs to the bacterial histone-like protein family K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000001224 107.0
TLS3_k127_6091169_17 - - - - 0.0000000000000000305 86.0
TLS3_k127_6091169_2 PFAM Sodium sulphate symporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 551.0
TLS3_k127_6091169_3 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 538.0
TLS3_k127_6091169_4 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 422.0
TLS3_k127_6091169_5 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
TLS3_k127_6091169_6 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 334.0
TLS3_k127_6091169_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
TLS3_k127_6091169_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000085 273.0
TLS3_k127_6091169_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
TLS3_k127_6094787_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 0.0 1029.0
TLS3_k127_6094787_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 3.092e-268 829.0
TLS3_k127_6094787_10 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 593.0
TLS3_k127_6094787_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 578.0
TLS3_k127_6094787_12 COG0687 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 569.0
TLS3_k127_6094787_13 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 568.0
TLS3_k127_6094787_14 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 533.0
TLS3_k127_6094787_15 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 511.0
TLS3_k127_6094787_16 Rossmann fold nucleotide-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 470.0
TLS3_k127_6094787_17 Copper type II ascorbate-dependent monooxygenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 466.0
TLS3_k127_6094787_18 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 426.0
TLS3_k127_6094787_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 425.0
TLS3_k127_6094787_2 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.126e-258 806.0
TLS3_k127_6094787_20 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 427.0
TLS3_k127_6094787_21 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 422.0
TLS3_k127_6094787_22 Hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 401.0
TLS3_k127_6094787_23 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 404.0
TLS3_k127_6094787_24 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 355.0
TLS3_k127_6094787_25 KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 353.0
TLS3_k127_6094787_26 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 342.0
TLS3_k127_6094787_27 Acetyltransferase K06976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
TLS3_k127_6094787_28 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 346.0
TLS3_k127_6094787_29 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 299.0
TLS3_k127_6094787_3 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.458e-249 776.0
TLS3_k127_6094787_30 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 298.0
TLS3_k127_6094787_31 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001125 286.0
TLS3_k127_6094787_32 transcriptional K03718 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
TLS3_k127_6094787_33 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000001061 164.0
TLS3_k127_6094787_34 - - - - 0.000000000000000000000000000000000002275 152.0
TLS3_k127_6094787_35 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000003809 107.0
TLS3_k127_6094787_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 6.097e-231 718.0
TLS3_k127_6094787_5 COG1748 Saccharopine dehydrogenase and related K00290 - 1.5.1.7 4.919e-229 719.0
TLS3_k127_6094787_6 inorganic phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 1.037e-225 713.0
TLS3_k127_6094787_7 Na phosphate symporter K03324 - - 2.143e-202 646.0
TLS3_k127_6094787_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 1.693e-199 641.0
TLS3_k127_6094787_9 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 615.0
TLS3_k127_6121524_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1031.0
TLS3_k127_6121524_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 363.0
TLS3_k127_6121524_2 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002975 304.0
TLS3_k127_6121524_3 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000001135 226.0
TLS3_k127_6121524_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000004001 141.0
TLS3_k127_6149415_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 481.0
TLS3_k127_6149415_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 377.0
TLS3_k127_6149415_2 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 368.0
TLS3_k127_6149415_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 345.0
TLS3_k127_6149415_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000162 247.0
TLS3_k127_6149415_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000005133 104.0
TLS3_k127_6149415_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000001275 87.0
TLS3_k127_6149415_7 Acyl-CoA carboxylase epsilon subunit - - - 0.0000000002651 66.0
TLS3_k127_6179068_0 alpha-glucosidase K01187 - 3.2.1.20 4.014e-233 743.0
TLS3_k127_6179068_1 Bacterial extracellular solute-binding protein K10232 - - 1.395e-199 630.0
TLS3_k127_6179068_10 - - - - 0.000001373 61.0
TLS3_k127_6179068_2 DNA polymerase LigD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 544.0
TLS3_k127_6179068_3 lacI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 449.0
TLS3_k127_6179068_4 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 355.0
TLS3_k127_6179068_5 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 366.0
TLS3_k127_6179068_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001243 219.0
TLS3_k127_6179068_7 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000001013 205.0
TLS3_k127_6179068_8 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000005008 150.0
TLS3_k127_6179068_9 Phospholipid methyltransferase - - - 0.000000000000001453 82.0
TLS3_k127_621937_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007,K21787 - 2.7.9.2 0.0 1386.0
TLS3_k127_621937_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 3.623e-247 791.0
TLS3_k127_621937_10 SnoaL-like domain - - - 0.000000268 64.0
TLS3_k127_621937_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 3.459e-223 707.0
TLS3_k127_621937_3 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 5.331e-216 705.0
TLS3_k127_621937_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 473.0
TLS3_k127_621937_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 324.0
TLS3_k127_621937_6 isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
TLS3_k127_621937_7 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 326.0
TLS3_k127_621937_8 Domain of unknown function (DUF5063) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004394 247.0
TLS3_k127_621937_9 mercury ion transmembrane transporter activity - - - 0.0000000000002628 81.0
TLS3_k127_623508_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1732.0
TLS3_k127_623508_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.659e-246 763.0
TLS3_k127_623508_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000001793 89.0
TLS3_k127_623508_11 Yqey-like protein K09117 - - 0.000000000000002676 83.0
TLS3_k127_623508_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 421.0
TLS3_k127_623508_3 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 388.0
TLS3_k127_623508_4 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 366.0
TLS3_k127_623508_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 303.0
TLS3_k127_623508_6 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004166 261.0
TLS3_k127_623508_7 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.0000000000000000000000000000000000000000000000000004706 189.0
TLS3_k127_623508_8 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000001274 190.0
TLS3_k127_623508_9 Septation ring formation regulator EzrA K13052 - - 0.000000000000000000000002052 112.0
TLS3_k127_6369031_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1275.0
TLS3_k127_6369031_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 595.0
TLS3_k127_6369031_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 566.0
TLS3_k127_6369031_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 517.0
TLS3_k127_6369031_4 acetylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 518.0
TLS3_k127_6369031_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 460.0
TLS3_k127_6369031_6 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 411.0
TLS3_k127_6369031_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 402.0
TLS3_k127_6369031_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 317.0
TLS3_k127_6369031_9 ACT domain K09707 - - 0.000000000000000000000000000005438 135.0
TLS3_k127_6372666_0 TIGRFAM Carbon-monoxide dehydrogenase, large subunit K03520 - 1.2.5.3 0.0 1416.0
TLS3_k127_6372666_1 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 619.0
TLS3_k127_6372666_10 DNA-binding transcription factor activity K16328 - 2.7.1.83 0.000000000000000000000000000000005637 132.0
TLS3_k127_6372666_11 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000001524 87.0
TLS3_k127_6372666_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 533.0
TLS3_k127_6372666_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 408.0
TLS3_k127_6372666_4 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 402.0
TLS3_k127_6372666_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
TLS3_k127_6372666_6 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 305.0
TLS3_k127_6372666_7 ATP- GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005614 282.0
TLS3_k127_6372666_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
TLS3_k127_6372666_9 PFAM Roadblock LC7 K07131 - - 0.0000000000000000000000000000000000000000000000004773 179.0
TLS3_k127_6386396_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 2.659e-212 673.0
TLS3_k127_6386396_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 606.0
TLS3_k127_6386396_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 550.0
TLS3_k127_6386396_3 Preprotein translocase subunit YidC K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 454.0
TLS3_k127_6386396_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 350.0
TLS3_k127_6386396_5 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000006339 244.0
TLS3_k127_6386396_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000004575 144.0
TLS3_k127_6386396_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.000000000000000000000000000000002487 133.0
TLS3_k127_6386396_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001153 79.0
TLS3_k127_6458057_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 469.0
TLS3_k127_6458057_1 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 375.0
TLS3_k127_6458057_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000005138 188.0
TLS3_k127_6534351_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1313.0
TLS3_k127_6534351_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 589.0
TLS3_k127_6534351_2 DEAD DEAH box helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 308.0
TLS3_k127_6534351_3 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 278.0
TLS3_k127_6534351_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
TLS3_k127_6534351_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000007921 193.0
TLS3_k127_6534351_6 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000021 145.0
TLS3_k127_6534351_7 - - - - 0.00000000000000000000000000000000175 138.0
TLS3_k127_6534351_8 VanZ like family - - - 0.0000000000000000000000009852 112.0
TLS3_k127_6552642_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 0.0 1090.0
TLS3_k127_6552642_1 Toxic anion resistance protein (TelA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 575.0
TLS3_k127_6552642_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 301.0
TLS3_k127_6552642_11 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006772 267.0
TLS3_k127_6552642_12 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
TLS3_k127_6552642_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000004931 215.0
TLS3_k127_6552642_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000006989 188.0
TLS3_k127_6552642_15 Divalent ion tolerance protein K03926 - - 0.0000000000000000000000001577 111.0
TLS3_k127_6552642_2 Belongs to the amidase family K01426 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 582.0
TLS3_k127_6552642_3 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 522.0
TLS3_k127_6552642_4 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 514.0
TLS3_k127_6552642_5 Domain of unknown function (DUF4921) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 481.0
TLS3_k127_6552642_6 tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 430.0
TLS3_k127_6552642_7 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 363.0
TLS3_k127_6552642_8 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 350.0
TLS3_k127_6552642_9 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
TLS3_k127_6613479_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.0 1205.0
TLS3_k127_6613479_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.009e-239 746.0
TLS3_k127_6613479_10 Integrase core domain - - - 0.000000000000000000003398 97.0
TLS3_k127_6613479_11 Integrase core domain - - - 0.00000000000006905 81.0
TLS3_k127_6613479_12 amine dehydrogenase activity - - - 0.000000000002529 79.0
TLS3_k127_6613479_13 Integrase core domain - - - 0.000000000007473 67.0
TLS3_k127_6613479_14 OST-HTH/LOTUS domain - - - 0.000000803 51.0
TLS3_k127_6613479_15 COG2801 Transposase and inactivated derivatives K07497 - - 0.0007 43.0
TLS3_k127_6613479_2 membrane K00728 GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.109 6.444e-213 677.0
TLS3_k127_6613479_3 succinate dehydrogenase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 460.0
TLS3_k127_6613479_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 389.0
TLS3_k127_6613479_5 protease K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 375.0
TLS3_k127_6613479_6 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 292.0
TLS3_k127_6613479_7 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005135 280.0
TLS3_k127_6613479_8 Polysaccharide deacetylase K01181,K22278 - 3.2.1.8,3.5.1.104 0.000000000000000000000000000000000000000000000000004404 198.0
TLS3_k127_6613479_9 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000002474 132.0
TLS3_k127_6631466_0 phenylacetic acid degradation K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 452.0
TLS3_k127_6631466_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 419.0
TLS3_k127_6631466_2 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 394.0
TLS3_k127_6631466_3 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 318.0
TLS3_k127_6631466_4 SatD family (SatD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001475 242.0
TLS3_k127_6631466_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000431 209.0
TLS3_k127_6631466_6 - - - - 0.0000000000000000000000000000000000000000000000000008993 195.0
TLS3_k127_6631466_7 - - - - 0.00000000000000000000000000000000000000000000000135 179.0
TLS3_k127_6631466_8 Iron-sulfur cluster assembly protein K02612 - - 0.0000000000000000000000000000000000000000000002385 186.0
TLS3_k127_6828003_0 Serine phosphatase RsbU, regulator of sigma subunit - - - 6.272e-212 682.0
TLS3_k127_6828003_1 Belongs to the sigma-70 factor family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 629.0
TLS3_k127_6828003_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 505.0
TLS3_k127_6828003_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 423.0
TLS3_k127_6828003_4 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001655 243.0
TLS3_k127_6828003_5 - - - - 0.0000000000000000000000000000000000000000001666 162.0
TLS3_k127_6828003_6 - - - - 0.00000000000000000000000000000000000000001001 156.0
TLS3_k127_6828003_7 Polysaccharide lyase - - - 0.00000000000000000000000000000000007645 148.0
TLS3_k127_6828003_8 Phage integrase family - - - 0.000003562 53.0
TLS3_k127_6828003_9 Belongs to the 'phage' integrase family - - - 0.0002177 44.0
TLS3_k127_6908875_0 UPF0182 protein K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1323.0
TLS3_k127_6908875_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 442.0
TLS3_k127_6908875_2 Belongs to the peptidase S16 family K07177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001043 294.0
TLS3_k127_6908875_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002961 237.0
TLS3_k127_6908875_4 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000003574 181.0
TLS3_k127_6908875_5 MoaE protein K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.000000000000000000000000000000000000002804 168.0
TLS3_k127_6908875_6 - - - - 0.00000000000000000000008737 107.0
TLS3_k127_6908875_7 - - - - 0.0000001036 53.0
TLS3_k127_6951109_0 Predicted membrane protein (DUF2207) - - - 6.684e-206 659.0
TLS3_k127_6951109_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 586.0
TLS3_k127_6951109_2 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 406.0
TLS3_k127_6951109_3 Cell division K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 357.0
TLS3_k127_6951109_4 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 313.0
TLS3_k127_6951109_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007392 251.0
TLS3_k127_6951109_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 246.0
TLS3_k127_7121377_0 Fe-S oxidoreductase - - - 0.0 1219.0
TLS3_k127_7121377_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 1.211e-270 863.0
TLS3_k127_7121377_2 AMP-dependent synthetase K01897 - 6.2.1.3 2.069e-261 819.0
TLS3_k127_7121377_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 1.009e-234 732.0
TLS3_k127_7121377_4 Radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 323.0
TLS3_k127_7121377_5 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000002224 116.0
TLS3_k127_7121377_6 PFAM von Willebrand factor type A K07114 - - 0.000000001835 71.0
TLS3_k127_7137743_0 Domain of unknown function (DUF4032) - - - 2.79e-218 682.0
TLS3_k127_7137743_1 Belongs to the ABC transporter superfamily K10112 - - 1.176e-198 623.0
TLS3_k127_7137743_10 Protein of unknown function (DUF2752) - - - 0.000000000000000000000000000005751 123.0
TLS3_k127_7137743_11 - - - - 0.0000000000000000000000000008604 116.0
TLS3_k127_7137743_12 overlaps another CDS with the same product name K07071 - - 0.00000000000000000000000277 102.0
TLS3_k127_7137743_13 - - - - 0.000000000000000005049 91.0
TLS3_k127_7137743_14 Protein of unknown function (DUF433) - - - 0.0000000000000000258 84.0
TLS3_k127_7137743_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 553.0
TLS3_k127_7137743_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
TLS3_k127_7137743_4 Threonine/Serine exporter, ThrE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 432.0
TLS3_k127_7137743_5 epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
TLS3_k127_7137743_6 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002266 246.0
TLS3_k127_7137743_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000006109 196.0
TLS3_k127_7137743_8 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000347 158.0
TLS3_k127_7137743_9 Histidine kinase - - - 0.00000000000000000000000000000000000007224 156.0
TLS3_k127_7143785_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0 1268.0
TLS3_k127_7143785_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.029e-306 955.0
TLS3_k127_7143785_2 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000000464 136.0
TLS3_k127_7143785_3 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000001455 138.0
TLS3_k127_7143785_5 - - - - 0.000000007639 64.0
TLS3_k127_7177499_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.0 1067.0
TLS3_k127_7177499_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 3.718e-250 787.0
TLS3_k127_7177499_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 340.0
TLS3_k127_7177499_11 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
TLS3_k127_7177499_12 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 327.0
TLS3_k127_7177499_13 Alkylated DNA repair protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 307.0
TLS3_k127_7177499_14 Belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000003611 198.0
TLS3_k127_7177499_15 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000007299 172.0
TLS3_k127_7177499_16 TIGRFAM TIGR03943 family protein - - - 0.0000000000000000000000000000000000001674 155.0
TLS3_k127_7177499_17 - - - - 0.0000000000000000000000001655 108.0
TLS3_k127_7177499_19 regulation of translation - - - 0.0000004958 55.0
TLS3_k127_7177499_2 tRNA-dihydrouridine synthase - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 6.271e-195 631.0
TLS3_k127_7177499_3 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 618.0
TLS3_k127_7177499_4 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 605.0
TLS3_k127_7177499_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 467.0
TLS3_k127_7177499_6 ABC transporter K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 406.0
TLS3_k127_7177499_7 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 390.0
TLS3_k127_7177499_8 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 349.0
TLS3_k127_7177499_9 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 347.0
TLS3_k127_7188615_0 cell wall binding repeat - - - 0.0 1877.0
TLS3_k127_7188615_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 479.0
TLS3_k127_7188615_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 392.0
TLS3_k127_7188615_3 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 293.0
TLS3_k127_7188615_4 AAA ATPase domain - - - 0.000000000000000000000002737 105.0
TLS3_k127_7188615_5 AAA ATPase domain - - - 0.000000001074 62.0
TLS3_k127_7197935_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
TLS3_k127_7197935_1 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 381.0
TLS3_k127_7197935_2 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 340.0
TLS3_k127_7197935_3 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000001288 213.0
TLS3_k127_7197935_4 Membrane - - - 0.000000000000000000000000000000000000000000000000000002361 194.0
TLS3_k127_7197935_5 Universal stress protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000005476 98.0
TLS3_k127_7197935_6 Animal haem peroxidase - - - 0.0007031 47.0
TLS3_k127_7201566_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1128.0
TLS3_k127_7201566_1 hydrolase, family 3 K17641 - - 0.0 1038.0
TLS3_k127_7201566_10 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 473.0
TLS3_k127_7201566_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 439.0
TLS3_k127_7201566_12 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 446.0
TLS3_k127_7201566_13 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 445.0
TLS3_k127_7201566_14 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 454.0
TLS3_k127_7201566_15 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 431.0
TLS3_k127_7201566_16 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 437.0
TLS3_k127_7201566_17 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 419.0
TLS3_k127_7201566_18 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 415.0
TLS3_k127_7201566_19 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 409.0
TLS3_k127_7201566_2 D-xylose metabolic process K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 1.329e-240 745.0
TLS3_k127_7201566_20 Binding-protein-dependent transport system inner membrane component K02026,K10119,K17243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 402.0
TLS3_k127_7201566_21 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 392.0
TLS3_k127_7201566_22 asparaginase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 375.0
TLS3_k127_7201566_23 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 372.0
TLS3_k127_7201566_24 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 355.0
TLS3_k127_7201566_25 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 344.0
TLS3_k127_7201566_26 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 349.0
TLS3_k127_7201566_27 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 333.0
TLS3_k127_7201566_28 binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 340.0
TLS3_k127_7201566_29 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 332.0
TLS3_k127_7201566_3 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.781e-213 669.0
TLS3_k127_7201566_30 phosphohistidine phosphatase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 333.0
TLS3_k127_7201566_31 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 342.0
TLS3_k127_7201566_32 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 306.0
TLS3_k127_7201566_33 May play a role in the intracellular transport of hydrophobic ligands - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 292.0
TLS3_k127_7201566_34 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.00000000000000000000000000000000000000000000000000000000000000000000006848 261.0
TLS3_k127_7201566_35 Aldose 1-epimerase K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
TLS3_k127_7201566_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000699 254.0
TLS3_k127_7201566_37 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000000000000000000000005746 224.0
TLS3_k127_7201566_38 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000004631 203.0
TLS3_k127_7201566_39 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000005765 201.0
TLS3_k127_7201566_4 Bacterial regulatory proteins, lacI family K02529,K17640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 562.0
TLS3_k127_7201566_40 - - - - 0.0000000000000000000000000000000000000000000000004793 185.0
TLS3_k127_7201566_41 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000002372 171.0
TLS3_k127_7201566_42 DNA-binding protein - - - 0.000000000000000000000000000000000000000000001426 171.0
TLS3_k127_7201566_43 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000003578 160.0
TLS3_k127_7201566_44 - - - - 0.000000000000000000000000000000000000000002192 167.0
TLS3_k127_7201566_45 Mannose-6-phosphate isomerase K01809,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000007459 154.0
TLS3_k127_7201566_46 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000000000000000005788 146.0
TLS3_k127_7201566_47 Transglycosylase associated protein - - - 0.000000000000000000000000000000005174 129.0
TLS3_k127_7201566_48 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000003584 130.0
TLS3_k127_7201566_49 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000000001255 123.0
TLS3_k127_7201566_5 Bacterial extracellular solute-binding protein K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 546.0
TLS3_k127_7201566_50 DsrE/DsrF-like family - - - 0.000000000000000000000000000001563 134.0
TLS3_k127_7201566_51 Protein of unknown function (DUF2516) - - - 0.00000000000000000000000005867 109.0
TLS3_k127_7201566_52 redox-active disulfide protein 2 - - - 0.0000000000000000001421 102.0
TLS3_k127_7201566_53 ThiS family - - - 0.0000000000000004465 81.0
TLS3_k127_7201566_54 - - - - 0.000000653 53.0
TLS3_k127_7201566_55 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000467 52.0
TLS3_k127_7201566_6 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 539.0
TLS3_k127_7201566_7 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 504.0
TLS3_k127_7201566_8 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 495.0
TLS3_k127_7201566_9 3-keto-5-aminohexanoate cleavage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 486.0
TLS3_k127_7202_0 Cell division protein FtsK K03466 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0 1072.0
TLS3_k127_7202_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.429e-295 927.0
TLS3_k127_7202_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 355.0
TLS3_k127_7202_3 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 343.0
TLS3_k127_7202_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004311 241.0
TLS3_k127_7202_5 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000002946 122.0
TLS3_k127_7202_6 Psort location Cytoplasmic, score - - - 0.00000000000000000002636 102.0
TLS3_k127_7214711_0 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 338.0
TLS3_k127_7214711_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001791 228.0
TLS3_k127_7214711_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000006325 168.0
TLS3_k127_7214711_3 Belongs to the TPP enzyme family - - - 0.00000000000000002013 97.0
TLS3_k127_7214711_4 Domain of unknown function (DUF427) - - - 0.000000002205 62.0
TLS3_k127_729287_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1088.0
TLS3_k127_729287_1 Dehydrogenase K00074 - 1.1.1.157 1.193e-312 966.0
TLS3_k127_729287_10 Protein of unknown function (DUF2550) - - - 0.0000000000000003512 84.0
TLS3_k127_729287_11 - - - - 0.000000000000578 75.0
TLS3_k127_729287_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 8.17e-293 904.0
TLS3_k127_729287_3 NADPH quinone reductase K17829 - 1.3.1.86 2.865e-194 606.0
TLS3_k127_729287_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 449.0
TLS3_k127_729287_5 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 412.0
TLS3_k127_729287_6 Cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 311.0
TLS3_k127_729287_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000005097 140.0
TLS3_k127_729287_8 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000129 141.0
TLS3_k127_729287_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000007939 129.0
TLS3_k127_7293278_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1005.0
TLS3_k127_7293278_1 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 439.0
TLS3_k127_7293278_2 Dyp-type peroxidase family K15733 - 1.11.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 427.0
TLS3_k127_7293278_3 AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 394.0
TLS3_k127_7293278_4 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 385.0
TLS3_k127_7293278_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 386.0
TLS3_k127_7293278_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
TLS3_k127_7293278_7 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000001156 132.0
TLS3_k127_7302179_0 Belongs to the major facilitator superfamily K07001 - - 4.321e-278 889.0
TLS3_k127_7302179_1 Multidrug transporter MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 599.0
TLS3_k127_7302179_2 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 556.0
TLS3_k127_7302179_3 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 539.0
TLS3_k127_7302179_4 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 487.0
TLS3_k127_7302179_5 Periplasmic binding protein domain K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 374.0
TLS3_k127_7302179_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
TLS3_k127_7302179_7 - - - - 0.0000000000000000000000000000000000000000000000000000000103 208.0
TLS3_k127_7302179_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001823 204.0
TLS3_k127_7302179_9 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000004915 184.0
TLS3_k127_7334433_0 cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 7.165e-221 694.0
TLS3_k127_7334433_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 1.017e-194 610.0
TLS3_k127_7334433_2 ABC transporter K16013,K16014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 593.0
TLS3_k127_7334433_3 Cytochrome C oxidase assembly protein K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 472.0
TLS3_k127_7334433_4 ABC transporter, ATP-binding protein K06148,K16012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 411.0
TLS3_k127_7334433_5 Predicted membrane protein (DUF2254) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 314.0
TLS3_k127_7334433_6 Von Willebrand factor - - - 0.000000000003149 67.0
TLS3_k127_7351485_0 Multicopper oxidase K00368 - 1.7.2.1 8.262e-298 942.0
TLS3_k127_7351485_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000222 217.0
TLS3_k127_7351485_2 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000005328 139.0
TLS3_k127_7351485_3 IclR helix-turn-helix domain - - - 0.000000000000000000000000000003825 130.0
TLS3_k127_7351485_4 cytochrome P-450 K00493 - 1.14.14.1 0.0003365 45.0
TLS3_k127_7384019_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0 1432.0
TLS3_k127_7384019_1 The glycine cleavage system catalyzes the degradation of glycine - - - 0.0 1330.0
TLS3_k127_7384019_10 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 543.0
TLS3_k127_7384019_11 Glutamine amidotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 542.0
TLS3_k127_7384019_12 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 442.0
TLS3_k127_7384019_13 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 404.0
TLS3_k127_7384019_14 Nitronate monooxygenase K00459 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 378.0
TLS3_k127_7384019_15 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 299.0
TLS3_k127_7384019_17 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
TLS3_k127_7384019_18 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001124 261.0
TLS3_k127_7384019_19 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001314 222.0
TLS3_k127_7384019_2 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 1.048e-318 1015.0
TLS3_k127_7384019_20 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002963 224.0
TLS3_k127_7384019_21 SAM dependent carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000004721 199.0
TLS3_k127_7384019_22 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000000000000000000021 123.0
TLS3_k127_7384019_23 Ester cyclase - - - 0.0000000000000000000000000006541 132.0
TLS3_k127_7384019_24 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000009124 123.0
TLS3_k127_7384019_25 Histidine kinase - - - 0.0000000000006652 74.0
TLS3_k127_7384019_26 - - - - 0.00004 56.0
TLS3_k127_7384019_3 Belongs to the glutamate synthase family - - - 9.436e-290 894.0
TLS3_k127_7384019_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.044e-283 873.0
TLS3_k127_7384019_5 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 1.686e-236 738.0
TLS3_k127_7384019_6 flavoprotein involved in K transport K18277 - 1.14.13.148 2.356e-231 728.0
TLS3_k127_7384019_7 Glutathione S-transferase K07393 - 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 599.0
TLS3_k127_7384019_8 Ammonium transporter family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 591.0
TLS3_k127_7384019_9 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 546.0
TLS3_k127_7467441_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.0 1252.0
TLS3_k127_7467441_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1043.0
TLS3_k127_7467441_10 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
TLS3_k127_7467441_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 449.0
TLS3_k127_7467441_12 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 428.0
TLS3_k127_7467441_13 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 379.0
TLS3_k127_7467441_14 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 376.0
TLS3_k127_7467441_15 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 343.0
TLS3_k127_7467441_16 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000002984 244.0
TLS3_k127_7467441_17 ABC-type cobalt transport system, ATPase component K16784 - - 0.000000000000000000000000000000000000000000000000000000000000001226 229.0
TLS3_k127_7467441_18 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000000000000000000000000000000000000004174 214.0
TLS3_k127_7467441_19 - - - - 0.0000000000000000000000000000000000000000000002204 174.0
TLS3_k127_7467441_2 Trehalose synthase K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 0.0 1019.0
TLS3_k127_7467441_20 BioY family K03523 - - 0.000000000000000000000000000000000000000000001107 176.0
TLS3_k127_7467441_21 ABC-type cobalt transport system permease component CbiQ K16783 - - 0.000000000000000000000000002193 119.0
TLS3_k127_7467441_22 Bacterial PH domain - - - 0.0000000000000000000003974 105.0
TLS3_k127_7467441_23 - - - - 0.00000000000005675 86.0
TLS3_k127_7467441_3 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 7.973e-317 998.0
TLS3_k127_7467441_4 Phosphoglucomutase K01835 - 5.4.2.2 1.156e-311 965.0
TLS3_k127_7467441_5 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.552e-285 892.0
TLS3_k127_7467441_6 ligase activity - - - 1.074e-232 724.0
TLS3_k127_7467441_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 3.974e-230 722.0
TLS3_k127_7467441_8 Aminoglycoside phosphotransferase K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.7.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 574.0
TLS3_k127_7467441_9 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 515.0
TLS3_k127_7492295_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1116.0
TLS3_k127_7492295_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 583.0
TLS3_k127_7492295_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 516.0
TLS3_k127_7492295_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 331.0
TLS3_k127_7492295_4 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 326.0
TLS3_k127_7492295_5 Signal transduction histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 297.0
TLS3_k127_7492295_6 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002624 287.0
TLS3_k127_7492295_7 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
TLS3_k127_7492295_8 - - - - 0.000000000000000000000005917 111.0
TLS3_k127_7492295_9 Belongs to the universal stress protein A family - - - 0.000000000000000000006971 97.0
TLS3_k127_7547068_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 1.838e-226 708.0
TLS3_k127_7547068_1 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 590.0
TLS3_k127_7547068_2 MFS transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 580.0
TLS3_k127_7547068_3 lycopene cyclase K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 432.0
TLS3_k127_7547068_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000138 235.0
TLS3_k127_7547068_5 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001741 228.0
TLS3_k127_7547068_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000007294 199.0
TLS3_k127_7547068_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000006071 96.0
TLS3_k127_7547068_8 - - - - 0.0000000000000002826 81.0
TLS3_k127_7609758_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 2.2e-284 887.0
TLS3_k127_7609758_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 550.0
TLS3_k127_7609758_2 With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 511.0
TLS3_k127_7609758_3 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 333.0
TLS3_k127_7609758_4 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002309 71.0
TLS3_k127_7617578_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1475.0
TLS3_k127_7617578_1 phosphorylase K00688 - 2.4.1.1 0.0 1326.0
TLS3_k127_7617578_10 Acyltransferase family - - - 3.035e-195 630.0
TLS3_k127_7617578_11 Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 580.0
TLS3_k127_7617578_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 552.0
TLS3_k127_7617578_13 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 544.0
TLS3_k127_7617578_14 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 527.0
TLS3_k127_7617578_15 Major Facilitator Superfamily K18833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 526.0
TLS3_k127_7617578_16 Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
TLS3_k127_7617578_17 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 456.0
TLS3_k127_7617578_18 cystathionine gamma-synthase K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 455.0
TLS3_k127_7617578_19 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 443.0
TLS3_k127_7617578_2 peptidase M13 K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 7.912e-310 960.0
TLS3_k127_7617578_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 419.0
TLS3_k127_7617578_21 Zn-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 411.0
TLS3_k127_7617578_22 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 374.0
TLS3_k127_7617578_23 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 367.0
TLS3_k127_7617578_24 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 351.0
TLS3_k127_7617578_25 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 349.0
TLS3_k127_7617578_26 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
TLS3_k127_7617578_27 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 314.0
TLS3_k127_7617578_28 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001964 288.0
TLS3_k127_7617578_29 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003405 268.0
TLS3_k127_7617578_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.256e-269 842.0
TLS3_k127_7617578_30 metal-binding protein K07040 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003556 257.0
TLS3_k127_7617578_31 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
TLS3_k127_7617578_32 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
TLS3_k127_7617578_33 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001455 239.0
TLS3_k127_7617578_34 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000004043 224.0
TLS3_k127_7617578_35 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000006919 200.0
TLS3_k127_7617578_36 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000394 198.0
TLS3_k127_7617578_37 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000005979 198.0
TLS3_k127_7617578_38 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000001118 166.0
TLS3_k127_7617578_39 chorismate mutase K04092 - 5.4.99.5 0.000000000000000000000000000000000000000003532 157.0
TLS3_k127_7617578_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 4.2.1.33,4.2.1.35 5.156e-264 818.0
TLS3_k127_7617578_40 Protein of unknown function (DUF3515) - - - 0.00000000000000000000000000000000000000003844 161.0
TLS3_k127_7617578_41 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000000356 168.0
TLS3_k127_7617578_42 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000000005123 141.0
TLS3_k127_7617578_43 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000003459 126.0
TLS3_k127_7617578_44 AsnC family transcriptional regulator - - - 0.00000000000000000000000000000164 126.0
TLS3_k127_7617578_45 acyl-coA-binding protein - - - 0.0000000000000000000000000004987 117.0
TLS3_k127_7617578_46 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000002244 117.0
TLS3_k127_7617578_47 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000004402 98.0
TLS3_k127_7617578_48 GTP binding - - - 0.000000000000001742 80.0
TLS3_k127_7617578_49 - - - - 0.000000000231 64.0
TLS3_k127_7617578_5 ATP-dependent DNA helicase RecG K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 2.856e-261 824.0
TLS3_k127_7617578_50 recombinase activity - - - 0.0009127 49.0
TLS3_k127_7617578_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.334e-256 797.0
TLS3_k127_7617578_7 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 2.171e-242 776.0
TLS3_k127_7617578_8 2-Nitropropane dioxygenase - - - 1.637e-238 745.0
TLS3_k127_7617578_9 Ammonium Transporter Family K03320 - - 3.082e-202 638.0
TLS3_k127_7661629_0 synthetase K01897 - 6.2.1.3 2.334e-291 904.0
TLS3_k127_7661629_1 PA domain - - - 1.423e-226 715.0
TLS3_k127_7661629_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 338.0
TLS3_k127_7661629_11 Bacterial regulatory helix-turn-helix protein, lysR family K05596 GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003700,GO:0005488,GO:0006275,GO:0006355,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
TLS3_k127_7661629_12 Phenazine biosynthesis protein PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 317.0
TLS3_k127_7661629_13 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 306.0
TLS3_k127_7661629_14 membrane K20469 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 302.0
TLS3_k127_7661629_15 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686 281.0
TLS3_k127_7661629_16 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000608 266.0
TLS3_k127_7661629_17 LysE type translocator K06895 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
TLS3_k127_7661629_18 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003715 200.0
TLS3_k127_7661629_19 Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
TLS3_k127_7661629_2 arylsulfatase activity - - - 6.113e-225 720.0
TLS3_k127_7661629_20 Protein of unknown function (DUF4446) - - - 0.0000000000000000000000000000000000000000000000004166 178.0
TLS3_k127_7661629_21 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000252 121.0
TLS3_k127_7661629_3 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 542.0
TLS3_k127_7661629_4 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 436.0
TLS3_k127_7661629_5 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 435.0
TLS3_k127_7661629_6 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 420.0
TLS3_k127_7661629_7 TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter K11104,K16209,K16248 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 425.0
TLS3_k127_7661629_8 SEC-C motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 359.0
TLS3_k127_7661629_9 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 358.0
TLS3_k127_7706839_0 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 2.362e-214 677.0
TLS3_k127_7706839_1 peptidase M4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 524.0
TLS3_k127_7706839_2 XRE family transcriptional regulator K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 320.0
TLS3_k127_7706839_3 Zn-dependent K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 326.0
TLS3_k127_7706839_4 CarD family transcriptional regulator K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 295.0
TLS3_k127_7706839_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003489 267.0
TLS3_k127_7706839_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000005771 247.0
TLS3_k127_7706839_7 Winged helix DNA-binding domain - - - 0.00000000000000000000000002411 116.0
TLS3_k127_7706839_8 - - - - 0.0000000000001719 77.0
TLS3_k127_7769277_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 598.0
TLS3_k127_7769277_1 Binding-protein-dependent transport system inner membrane component K10241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 469.0
TLS3_k127_7769277_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 450.0
TLS3_k127_7769277_3 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 437.0
TLS3_k127_7769277_4 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 286.0
TLS3_k127_7772888_0 probably involved in cell wall - - - 3.669e-239 762.0
TLS3_k127_7772888_1 tetrahydromethanopterin reductase - - - 1.308e-218 692.0
TLS3_k127_7772888_2 Allophanate hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
TLS3_k127_7772888_3 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 355.0
TLS3_k127_7772888_4 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 330.0
TLS3_k127_7772888_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 302.0
TLS3_k127_7772888_6 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
TLS3_k127_7772888_7 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007806 273.0
TLS3_k127_7772888_8 - - - - 0.00000000000000002207 94.0
TLS3_k127_7772888_9 Psort location Cytoplasmic, score - - - 0.00000000000005958 74.0
TLS3_k127_7833213_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1597.0
TLS3_k127_7833213_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1573.0
TLS3_k127_7833213_10 Orn Lys Arg decarboxylase K01585 - 4.1.1.19 2.119e-210 671.0
TLS3_k127_7833213_11 Sugar ABC transporter substrate-binding protein K10232 - - 6.871e-208 656.0
TLS3_k127_7833213_12 Contains 3'-5'exonuclease domain K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 3.549e-199 640.0
TLS3_k127_7833213_13 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 621.0
TLS3_k127_7833213_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 587.0
TLS3_k127_7833213_15 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 517.0
TLS3_k127_7833213_16 Ubiquinol-cytochrome C reductase K03890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 512.0
TLS3_k127_7833213_17 Ribokinase K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 508.0
TLS3_k127_7833213_18 glucokinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 479.0
TLS3_k127_7833213_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 477.0
TLS3_k127_7833213_2 DNA topoisomerase (ATP-hydrolyzing) K02469 - 5.99.1.3 0.0 1236.0
TLS3_k127_7833213_20 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 476.0
TLS3_k127_7833213_21 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 467.0
TLS3_k127_7833213_22 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 452.0
TLS3_k127_7833213_23 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 436.0
TLS3_k127_7833213_24 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 431.0
TLS3_k127_7833213_25 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 435.0
TLS3_k127_7833213_26 nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 421.0
TLS3_k127_7833213_27 Cytochrome c oxidase subunit K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 402.0
TLS3_k127_7833213_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 400.0
TLS3_k127_7833213_29 Aminotransferase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 396.0
TLS3_k127_7833213_3 DNA topoisomerase (ATP-hydrolyzing) K02470 - 5.99.1.3 0.0 1154.0
TLS3_k127_7833213_30 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 389.0
TLS3_k127_7833213_31 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 380.0
TLS3_k127_7833213_32 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 379.0
TLS3_k127_7833213_33 Cytochrome K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 360.0
TLS3_k127_7833213_34 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
TLS3_k127_7833213_35 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 361.0
TLS3_k127_7833213_36 Portal protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 360.0
TLS3_k127_7833213_37 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 360.0
TLS3_k127_7833213_38 Cystathionine beta-lyase K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 341.0
TLS3_k127_7833213_39 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 337.0
TLS3_k127_7833213_4 Multidrug ABC transporter permease - - - 0.0 1084.0
TLS3_k127_7833213_40 Periplasmic binding protein-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 345.0
TLS3_k127_7833213_41 Potassium transporter TrkA K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 344.0
TLS3_k127_7833213_42 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 317.0
TLS3_k127_7833213_43 DNA-binding protein - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 310.0
TLS3_k127_7833213_44 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 304.0
TLS3_k127_7833213_45 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 305.0
TLS3_k127_7833213_46 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 310.0
TLS3_k127_7833213_47 Protein of unknown function (DUF3159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003857 271.0
TLS3_k127_7833213_48 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 268.0
TLS3_k127_7833213_49 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006312 272.0
TLS3_k127_7833213_5 DNA-binding protein - - - 1.787e-316 993.0
TLS3_k127_7833213_50 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
TLS3_k127_7833213_51 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
TLS3_k127_7833213_52 Protein of unknown function (DUF3710) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003422 242.0
TLS3_k127_7833213_53 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
TLS3_k127_7833213_54 Regulator - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000008115 205.0
TLS3_k127_7833213_55 Domain of unknown function (DUF4193) - - - 0.00000000000000000000000000000000000000000000000003545 179.0
TLS3_k127_7833213_56 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000006971 183.0
TLS3_k127_7833213_57 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000002999 178.0
TLS3_k127_7833213_58 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000006959 179.0
TLS3_k127_7833213_59 transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000001071 175.0
TLS3_k127_7833213_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 4.101e-314 968.0
TLS3_k127_7833213_60 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000004522 171.0
TLS3_k127_7833213_61 Belongs to the cytochrome c oxidase bacterial subunit CtaF family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000009739 169.0
TLS3_k127_7833213_62 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000001153 155.0
TLS3_k127_7833213_63 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000008457 123.0
TLS3_k127_7833213_64 - - - - 0.00000000000000000000000009205 111.0
TLS3_k127_7833213_65 - - - - 0.000000000000000000000002547 115.0
TLS3_k127_7833213_66 Protein of unknown function (DUF3040) - - - 0.0000000000000000000006047 102.0
TLS3_k127_7833213_67 - - - - 0.000000000000000000005732 100.0
TLS3_k127_7833213_68 aminopeptidase N - - - 0.00000000000000001111 96.0
TLS3_k127_7833213_69 Nucleic acid binding, OB-fold, tRNA - - - 0.0000000000000007189 84.0
TLS3_k127_7833213_7 Cytochrome B subunit K03891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.614e-278 864.0
TLS3_k127_7833213_70 Belongs to the UPF0235 family K09131 - - 0.0000000000001541 78.0
TLS3_k127_7833213_71 - - - - 0.000000000005232 70.0
TLS3_k127_7833213_72 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000007293 68.0
TLS3_k127_7833213_73 - - - - 0.0001392 50.0
TLS3_k127_7833213_74 - - - - 0.0004768 49.0
TLS3_k127_7833213_8 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 3.982e-246 766.0
TLS3_k127_7833213_9 Belongs to the acetyltransferase family. ArgA subfamily K00619,K00930,K14682 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0004358,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 2.495e-228 716.0
TLS3_k127_7834863_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 0.0 1391.0
TLS3_k127_7834863_1 acyl-CoA synthetase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 616.0
TLS3_k127_7834863_2 TipAS antibiotic-recognition domain K21744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
TLS3_k127_7834863_3 HEAT repeats - - - 0.000000000000000000000000000000003729 138.0
TLS3_k127_793227_0 Belongs to the glutamine synthetase family K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 3.656e-264 816.0
TLS3_k127_793227_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.505e-212 669.0
TLS3_k127_793227_10 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 321.0
TLS3_k127_793227_11 Zn-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 312.0
TLS3_k127_793227_12 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000000000000000002925 218.0
TLS3_k127_793227_13 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000004328 213.0
TLS3_k127_793227_14 - - - - 0.00000000000000000000000000000000000000000000000002849 184.0
TLS3_k127_793227_15 - - - - 0.00000000000000000000000000000000003958 144.0
TLS3_k127_793227_17 - - - - 0.00000000000000000000000534 109.0
TLS3_k127_793227_18 - - - - 0.0000000000000000001263 90.0
TLS3_k127_793227_19 - - - - 0.000000000000009866 75.0
TLS3_k127_793227_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 607.0
TLS3_k127_793227_3 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 589.0
TLS3_k127_793227_4 ribonuclease II K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 542.0
TLS3_k127_793227_5 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 537.0
TLS3_k127_793227_6 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 507.0
TLS3_k127_793227_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 507.0
TLS3_k127_793227_8 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 412.0
TLS3_k127_793227_9 Reverse transcriptase-like K03469,K22316 - 3.1.26.4,3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 347.0
TLS3_k127_7958806_0 of the RND superfamily K06994 - - 0.0 1058.0
TLS3_k127_7958806_1 ABC transporter - - - 0.0 1054.0
TLS3_k127_7958806_10 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 314.0
TLS3_k127_7958806_11 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004427 250.0
TLS3_k127_7958806_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 249.0
TLS3_k127_7958806_13 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
TLS3_k127_7958806_14 YjbR - - - 0.0000000000000000000000000000000000000000000000000003071 188.0
TLS3_k127_7958806_15 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000004008 196.0
TLS3_k127_7958806_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000007124 179.0
TLS3_k127_7958806_17 - - - - 0.00000000000000000000001047 110.0
TLS3_k127_7958806_18 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000007114 70.0
TLS3_k127_7958806_19 Predicted membrane protein (DUF2306) - - - 0.000001383 55.0
TLS3_k127_7958806_2 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 1.643e-228 717.0
TLS3_k127_7958806_20 - - - - 0.0007422 51.0
TLS3_k127_7958806_3 AP endonuclease family 2 C terminus - - - 8.951e-205 649.0
TLS3_k127_7958806_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 576.0
TLS3_k127_7958806_5 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 526.0
TLS3_k127_7958806_6 membrane K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 539.0
TLS3_k127_7958806_7 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 508.0
TLS3_k127_7958806_8 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 495.0
TLS3_k127_7958806_9 helix_turn_helix isocitrate lyase regulation K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 384.0
TLS3_k127_8026859_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.797e-289 906.0
TLS3_k127_8026859_1 ABC transporter K02056 - 3.6.3.17 7.818e-258 804.0
TLS3_k127_8026859_10 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 456.0
TLS3_k127_8026859_11 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 416.0
TLS3_k127_8026859_12 Tryptophanyl-tRNA synthetase K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 404.0
TLS3_k127_8026859_13 ATP-binding protein K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 259.0
TLS3_k127_8026859_14 cytidine deaminase K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000000000000000000005292 222.0
TLS3_k127_8026859_15 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000009072 227.0
TLS3_k127_8026859_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001381 193.0
TLS3_k127_8026859_17 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K00980 - 2.7.7.39 0.000000000000000000000000000000000000000000004779 188.0
TLS3_k127_8026859_2 pyrimidine-nucleoside phosphorylase K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 2.425e-222 696.0
TLS3_k127_8026859_3 Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 581.0
TLS3_k127_8026859_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 580.0
TLS3_k127_8026859_5 amidohydrolase K01436,K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 530.0
TLS3_k127_8026859_6 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 517.0
TLS3_k127_8026859_7 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 502.0
TLS3_k127_8026859_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 498.0
TLS3_k127_8026859_9 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
TLS3_k127_8049194_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1081.0
TLS3_k127_8049194_1 Bacterial protein of unknown function (DUF853) K06915 - - 1.047e-250 790.0
TLS3_k127_8049194_10 - - - - 0.00000000000000007365 81.0
TLS3_k127_8049194_11 LytR cell envelope-related transcriptional attenuator - - - 0.00000000000001605 83.0
TLS3_k127_8049194_13 cell wall organization - - - 0.00007484 49.0
TLS3_k127_8049194_14 N-acetylmuramoyl-L-alanine amidase - - - 0.0001193 46.0
TLS3_k127_8049194_2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone K15510 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019725,GO:0030312,GO:0031406,GO:0036094,GO:0042592,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046983,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0055114,GO:0065007,GO:0065008,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 1.1.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 534.0
TLS3_k127_8049194_3 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 407.0
TLS3_k127_8049194_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 367.0
TLS3_k127_8049194_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000003306 211.0
TLS3_k127_8049194_6 - - - - 0.00000000000000000000000000000000000000000000000000008691 189.0
TLS3_k127_8049194_7 Transcription regulator of the Arc MetJ class - - - 0.000000000000000000000000000000000000000000001417 166.0
TLS3_k127_8049194_8 Domain of unknown function (DUF3817) - - - 0.0000000000000000000000000000000000000001753 162.0
TLS3_k127_8049194_9 PFAM CHAD domain containing protein - - - 0.000000000000000000000000000000000001848 153.0
TLS3_k127_8055923_0 Protein kinase G tetratricopeptide repeat K14949 - 2.7.11.1 6.161e-320 1012.0
TLS3_k127_8055923_1 von Willebrand factor type A domain - - - 9.923e-195 620.0
TLS3_k127_8055923_2 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 392.0
TLS3_k127_8055923_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 381.0
TLS3_k127_8055923_4 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 370.0
TLS3_k127_8055923_5 phosphoserine phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 304.0
TLS3_k127_8055923_6 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004202 290.0
TLS3_k127_8055923_7 Enoyl reductase K12445 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000002729 238.0
TLS3_k127_8055923_8 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000002003 181.0
TLS3_k127_8092026_0 Type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.104e-296 917.0
TLS3_k127_8092026_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 6.831e-232 722.0
TLS3_k127_8092026_2 Protein of unknown function (DUF2786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006389 257.0
TLS3_k127_8092026_3 AsnC family transcriptional regulator K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000004609 227.0
TLS3_k127_8092026_4 SnoaL-like polyketide cyclase - - - 0.0000000000000001964 94.0
TLS3_k127_8143161_0 Glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2317.0
TLS3_k127_8143161_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1334.0
TLS3_k127_8143161_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 358.0
TLS3_k127_8143161_11 phosphatidylcholine synthase K01004 - 2.7.8.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 346.0
TLS3_k127_8143161_12 membrane K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
TLS3_k127_8143161_13 Regulator K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 316.0
TLS3_k127_8143161_14 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 305.0
TLS3_k127_8143161_15 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 256.0
TLS3_k127_8143161_16 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000002895 215.0
TLS3_k127_8143161_17 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000001237 199.0
TLS3_k127_8143161_18 Methylamine utilisation protein MauE - - - 0.0000000000000000000000000000000000000000000000007039 184.0
TLS3_k127_8143161_19 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000652 175.0
TLS3_k127_8143161_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.452e-253 792.0
TLS3_k127_8143161_20 Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139 3.6.1.31 0.000000000000000000000000000000000000000414 150.0
TLS3_k127_8143161_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001586 151.0
TLS3_k127_8143161_22 Bacterial PH domain - - - 0.000000000000000000000000000000001922 145.0
TLS3_k127_8143161_23 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000008879 123.0
TLS3_k127_8143161_24 Tryptophan-associated transmembrane protein (Trp_oprn_chp) - - - 0.0000000000000000000000009543 112.0
TLS3_k127_8143161_25 Catalyzes the formation of phosphoenolpyruvate from pyruvate K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00001992 49.0
TLS3_k127_8143161_3 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 2.77e-251 788.0
TLS3_k127_8143161_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 4.929e-219 694.0
TLS3_k127_8143161_5 Catalyzes the formation of phosphoenolpyruvate from pyruvate K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 2.519e-210 662.0
TLS3_k127_8143161_6 ATP phosphoribosyltransferase K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
TLS3_k127_8143161_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 436.0
TLS3_k127_8143161_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 408.0
TLS3_k127_8143161_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 372.0
TLS3_k127_8266993_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 2.466e-271 841.0
TLS3_k127_8266993_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 605.0
TLS3_k127_8266993_10 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000001188 154.0
TLS3_k127_8266993_11 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000007176 53.0
TLS3_k127_8266993_12 - - - - 0.00000436 52.0
TLS3_k127_8266993_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 519.0
TLS3_k127_8266993_3 Belongs to the pyridoxine kinase family K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 497.0
TLS3_k127_8266993_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 338.0
TLS3_k127_8266993_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 313.0
TLS3_k127_8266993_6 Belongs to the phosphoglycerate mutase family K01834,K22306 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 0.00000000000000000000000000000000000000000000000000005255 199.0
TLS3_k127_8266993_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000151 181.0
TLS3_k127_8266993_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002528 176.0
TLS3_k127_8266993_9 YhhN family - - - 0.0000000000000000000000000000000000000006496 157.0
TLS3_k127_8304169_0 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 4.835e-308 952.0
TLS3_k127_8304169_1 Carboxyl transferase domain - - - 1.405e-247 773.0
TLS3_k127_8304169_10 Thioesterase - - - 0.0000000000000000000000000000005833 127.0
TLS3_k127_8304169_12 - - - - 0.000000006988 68.0
TLS3_k127_8304169_2 AAA domain, putative AbiEii toxin, Type IV TA system K18230 - - 8.976e-245 767.0
TLS3_k127_8304169_3 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 1.136e-237 740.0
TLS3_k127_8304169_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 546.0
TLS3_k127_8304169_5 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 445.0
TLS3_k127_8304169_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 384.0
TLS3_k127_8304169_7 endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 367.0
TLS3_k127_8304169_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000173 153.0
TLS3_k127_8304169_9 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000000000000000006355 153.0
TLS3_k127_8337654_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.914e-210 665.0
TLS3_k127_8337654_1 Histidine kinase K18350 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 340.0
TLS3_k127_8337654_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 331.0
TLS3_k127_8337654_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002097 265.0
TLS3_k127_8337654_4 ArsC family - - - 0.0000000000000000000000000000002656 141.0
TLS3_k127_8457150_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1389.0
TLS3_k127_8457150_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 5e-324 997.0
TLS3_k127_8457150_10 TOBE domain K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 451.0
TLS3_k127_8457150_11 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 444.0
TLS3_k127_8457150_12 ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 407.0
TLS3_k127_8457150_13 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 411.0
TLS3_k127_8457150_14 Dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
TLS3_k127_8457150_15 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
TLS3_k127_8457150_16 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 350.0
TLS3_k127_8457150_17 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 325.0
TLS3_k127_8457150_18 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
TLS3_k127_8457150_19 Belongs to the carbohydrate kinase PfkB family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
TLS3_k127_8457150_2 Beta-glucosidase K05350 - 3.2.1.21 3.021e-231 722.0
TLS3_k127_8457150_20 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
TLS3_k127_8457150_21 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
TLS3_k127_8457150_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001484 274.0
TLS3_k127_8457150_23 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003006 259.0
TLS3_k127_8457150_24 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000104 256.0
TLS3_k127_8457150_25 Protein of unknown function (DUF4245) - - - 0.000000000000000000000000000000000000000000001194 172.0
TLS3_k127_8457150_26 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000001281 93.0
TLS3_k127_8457150_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 4.089e-225 704.0
TLS3_k127_8457150_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 602.0
TLS3_k127_8457150_5 Bacterial extracellular solute-binding protein K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 593.0
TLS3_k127_8457150_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 524.0
TLS3_k127_8457150_7 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 463.0
TLS3_k127_8457150_8 DNA polymerase V K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 458.0
TLS3_k127_8457150_9 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
TLS3_k127_8461294_0 - - - - 3.264e-320 1018.0
TLS3_k127_8461294_1 Extracellular solute-binding protein K10240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 348.0
TLS3_k127_8461294_2 Ferric reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 241.0
TLS3_k127_8461294_3 domain, Protein - - - 0.0000000000000000000000000000000001294 145.0
TLS3_k127_8480081_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.039e-294 909.0
TLS3_k127_8480081_1 LPXTG-motif cell wall anchor domain - - - 4.746e-261 840.0
TLS3_k127_8480081_10 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000003215 150.0
TLS3_k127_8480081_11 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000002774 106.0
TLS3_k127_8480081_2 Domain of unknown function (DUF1727) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 610.0
TLS3_k127_8480081_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 558.0
TLS3_k127_8480081_4 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 466.0
TLS3_k127_8480081_5 CobB/CobQ-like glutamine amidotransferase domain K07009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 357.0
TLS3_k127_8480081_6 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003569 285.0
TLS3_k127_8480081_7 RyR domain - - - 0.0000000000000000000000000000000000000000000000000001946 205.0
TLS3_k127_8480081_8 SURF1-like protein - - - 0.00000000000000000000000000000000000000000000000003106 187.0
TLS3_k127_8480081_9 - - - - 0.0000000000000000000000000000000000000000000001467 179.0
TLS3_k127_879947_0 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 9.816e-255 828.0
TLS3_k127_879947_1 Sulfate permease family K03321 GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 5.387e-242 780.0
TLS3_k127_879947_10 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 346.0
TLS3_k127_879947_11 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000003852 180.0
TLS3_k127_879947_12 lacI family K02529,K05499 - - 0.00000000000000000000000000000000002363 138.0
TLS3_k127_879947_13 - - - - 0.000000000000000004523 91.0
TLS3_k127_879947_2 Glucuronate isomerase K01812 - 5.3.1.12 6.495e-233 729.0
TLS3_k127_879947_3 Domain of unknown function (DUF2088) - - - 3.747e-219 689.0
TLS3_k127_879947_4 Secretory lipase - - - 5.194e-202 649.0
TLS3_k127_879947_5 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 582.0
TLS3_k127_879947_6 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 430.0
TLS3_k127_879947_7 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 402.0
TLS3_k127_879947_8 glycolate biosynthetic process K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
TLS3_k127_879947_9 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 368.0
TLS3_k127_884157_0 Malonate decarboxylase gamma subunit (MdcE) K17489 - 2.1.3.1 4.439e-290 896.0
TLS3_k127_884157_1 Conserved carboxylase domain K03416 - 2.1.3.1 1.217e-282 874.0
TLS3_k127_884157_10 - K17489 - 2.1.3.1 0.0000000000000000003069 99.0
TLS3_k127_884157_2 2-phospho-L-lactate transferase K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 496.0
TLS3_k127_884157_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 422.0
TLS3_k127_884157_4 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000000000000000000000000000000000000000000000000000000000007268 234.0
TLS3_k127_884157_5 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000001618 179.0
TLS3_k127_884157_6 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000762 159.0
TLS3_k127_884157_7 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000000000001289 158.0
TLS3_k127_884157_8 Biotin-lipoyl like K17490 - 2.1.3.1 0.00000000000000000000000000000000000002969 146.0
TLS3_k127_884157_9 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.000000000000000000000000004976 122.0