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Overview

ID MAG04199
Name WLSH2_bin.20
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Paracaedibacterales
Family Paracaedibacteraceae
Genus
Species
Assembly information
Completeness (%) 86.54
Contamination (%) 0.12
GC content (%) 44.0
N50 (bp) 23,208
Genome size (bp) 2,150,706

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1534

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10220876_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 1.275e-237 743.0
WLSH2_k127_10220876_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 593.0
WLSH2_k127_10220876_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 449.0
WLSH2_k127_10220876_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 408.0
WLSH2_k127_10220876_4 ATPase domain predominantly from Archaea K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 373.0
WLSH2_k127_10220876_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000002044 206.0
WLSH2_k127_1041284_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.413e-239 752.0
WLSH2_k127_1041284_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 3.631e-221 703.0
WLSH2_k127_1041284_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 587.0
WLSH2_k127_1041284_3 COG3288 NAD NADP transhydrogenase alpha subunit K00324 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
WLSH2_k127_1041284_4 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 479.0
WLSH2_k127_1041284_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000000001517 201.0
WLSH2_k127_1041284_6 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000005252 186.0
WLSH2_k127_1041284_7 Golgin subfamily A member 4 K20283 GO:0000138,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005802,GO:0005829,GO:0006810,GO:0006892,GO:0006893,GO:0007275,GO:0007399,GO:0008104,GO:0008150,GO:0008361,GO:0009987,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016192,GO:0017016,GO:0017137,GO:0019899,GO:0022008,GO:0022603,GO:0022604,GO:0030154,GO:0030306,GO:0030307,GO:0030516,GO:0031267,GO:0031344,GO:0031346,GO:0031984,GO:0031985,GO:0032501,GO:0032502,GO:0032535,GO:0033036,GO:0034613,GO:0040008,GO:0042802,GO:0042803,GO:0042886,GO:0043001,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045927,GO:0046983,GO:0048193,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0051020,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051960,GO:0051962,GO:0060284,GO:0061387,GO:0061951,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090066,GO:0090150,GO:0098791,GO:0098876,GO:0120035,GO:1990778,GO:2000026 - 0.00007909 55.0
WLSH2_k127_10633501_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1026.0
WLSH2_k127_10633501_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.177e-232 724.0
WLSH2_k127_10633501_10 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 336.0
WLSH2_k127_10633501_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 336.0
WLSH2_k127_10633501_12 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 319.0
WLSH2_k127_10633501_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
WLSH2_k127_10633501_14 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 291.0
WLSH2_k127_10633501_15 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
WLSH2_k127_10633501_16 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008713 235.0
WLSH2_k127_10633501_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000002771 212.0
WLSH2_k127_10633501_18 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000007205 181.0
WLSH2_k127_10633501_19 unfolded protein binding K06142 - - 0.00000000000000000000000000000000000000000001301 169.0
WLSH2_k127_10633501_2 TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 509.0
WLSH2_k127_10633501_20 protein disulfide oxidoreductase activity K03611 - - 0.00000000000000000000000000000000000000006259 158.0
WLSH2_k127_10633501_21 Biotin-lipoyl like K02022 - - 0.000000000000000000000000000000002821 144.0
WLSH2_k127_10633501_22 AKAP7 2'5' RNA ligase-like domain K01975 - 3.1.4.58 0.0000000000000000444 88.0
WLSH2_k127_10633501_23 Belongs to the BolA IbaG family K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0106035,GO:1901564 - 0.0000000000001232 74.0
WLSH2_k127_10633501_24 - - - - 0.0000001316 53.0
WLSH2_k127_10633501_25 Endonuclease Exonuclease phosphatase - - - 0.000001265 51.0
WLSH2_k127_10633501_26 Endonuclease/Exonuclease/phosphatase family - - - 0.0001175 53.0
WLSH2_k127_10633501_3 Beta-lactamase K01467 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 491.0
WLSH2_k127_10633501_4 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 411.0
WLSH2_k127_10633501_5 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 399.0
WLSH2_k127_10633501_6 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 406.0
WLSH2_k127_10633501_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 391.0
WLSH2_k127_10633501_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 385.0
WLSH2_k127_10633501_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 361.0
WLSH2_k127_10843958_0 Belongs to the peptidase S1C family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
WLSH2_k127_10843958_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 562.0
WLSH2_k127_10843958_10 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
WLSH2_k127_10843958_11 ETC complex I subunit conserved region - - - 0.00000000000000000000000000000000003865 138.0
WLSH2_k127_10843958_12 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.00000000000000000000000000000002661 135.0
WLSH2_k127_10843958_13 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000005445 119.0
WLSH2_k127_10843958_14 Flagellar hook-length control protein FliK - - - 0.0000000000000000000007592 111.0
WLSH2_k127_10843958_15 peptidyl-tyrosine sulfation - - - 0.0000000000000000000009064 109.0
WLSH2_k127_10843958_17 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000001069 53.0
WLSH2_k127_10843958_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 540.0
WLSH2_k127_10843958_3 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 554.0
WLSH2_k127_10843958_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 462.0
WLSH2_k127_10843958_5 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 406.0
WLSH2_k127_10843958_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 390.0
WLSH2_k127_10843958_7 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 377.0
WLSH2_k127_10843958_8 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 368.0
WLSH2_k127_10843958_9 Ribonuclease D K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000002057 249.0
WLSH2_k127_11137066_0 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 1.093e-241 760.0
WLSH2_k127_11137066_1 Patatin-like phospholipase K07001 - - 3.883e-195 613.0
WLSH2_k127_11137066_10 - - - - 0.0000000000000000000000000000002461 128.0
WLSH2_k127_11137066_11 - - - - 0.000000000000000000000006711 109.0
WLSH2_k127_11137066_12 Helix-turn-helix domain - - - 0.000000000000002484 78.0
WLSH2_k127_11137066_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 422.0
WLSH2_k127_11137066_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 298.0
WLSH2_k127_11137066_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
WLSH2_k127_11137066_5 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 293.0
WLSH2_k127_11137066_6 protein related to capsule biosynthesis enzymes K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 294.0
WLSH2_k127_11137066_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003994 261.0
WLSH2_k127_11137066_8 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000003594 205.0
WLSH2_k127_11137066_9 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000003341 175.0
WLSH2_k127_11183788_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18989 - - 0.0 1284.0
WLSH2_k127_11183788_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 426.0
WLSH2_k127_11183788_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
WLSH2_k127_11183788_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 318.0
WLSH2_k127_11183788_4 Vesicular-fusion protein SEC18 K06027 GO:0000045,GO:0000149,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0005937,GO:0006810,GO:0006886,GO:0006888,GO:0006891,GO:0006892,GO:0006893,GO:0006906,GO:0006914,GO:0006996,GO:0007033,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016050,GO:0016192,GO:0016236,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022406,GO:0022411,GO:0022607,GO:0030427,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033036,GO:0034613,GO:0035494,GO:0035639,GO:0036094,GO:0042144,GO:0042886,GO:0042995,GO:0043001,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043332,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0045184,GO:0046907,GO:0048193,GO:0048211,GO:0048219,GO:0048278,GO:0048280,GO:0048284,GO:0051179,GO:0051234,GO:0051286,GO:0051640,GO:0051641,GO:0051649,GO:0061024,GO:0061025,GO:0061919,GO:0061951,GO:0070300,GO:0070727,GO:0070925,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090150,GO:0090174,GO:0097159,GO:0097367,GO:0097576,GO:0098876,GO:0120025,GO:0120038,GO:0140056,GO:1901265,GO:1901363,GO:1905037,GO:1990778 3.6.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 310.0
WLSH2_k127_11183788_5 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000001784 58.0
WLSH2_k127_11228938_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1242.0
WLSH2_k127_11228938_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.483e-229 713.0
WLSH2_k127_11228938_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.32e-198 629.0
WLSH2_k127_11228938_3 E1-E2 ATPase K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 567.0
WLSH2_k127_11228938_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K01487,K12960 - 3.5.4.28,3.5.4.3,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 473.0
WLSH2_k127_11228938_5 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 413.0
WLSH2_k127_11228938_6 HMGL-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 357.0
WLSH2_k127_11228938_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000294 258.0
WLSH2_k127_11228938_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000001583 198.0
WLSH2_k127_11228938_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000000002342 168.0
WLSH2_k127_11277634_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 1.545e-272 852.0
WLSH2_k127_11277634_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 398.0
WLSH2_k127_11277634_2 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007385 249.0
WLSH2_k127_11277634_3 - - - - 0.0000000000000002588 81.0
WLSH2_k127_11277634_4 ATPase domain predominantly from Archaea K06921 - - 0.0000000000000002762 79.0
WLSH2_k127_11277634_5 AAA ATPase domain K06921 - - 0.0000000001685 66.0
WLSH2_k127_11319858_0 Phosphate acyltransferases - - - 4.305e-280 889.0
WLSH2_k127_11319858_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.094e-247 777.0
WLSH2_k127_11319858_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 374.0
WLSH2_k127_11319858_11 L COG3436 Transposase and inactivated derivatives K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 313.0
WLSH2_k127_11319858_12 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 298.0
WLSH2_k127_11319858_13 Enoyl-(Acyl carrier protein) reductase K00038,K17754 - 1.1.1.163,1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 301.0
WLSH2_k127_11319858_14 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
WLSH2_k127_11319858_15 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
WLSH2_k127_11319858_16 Transmembrane protein 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006374 251.0
WLSH2_k127_11319858_17 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001106 251.0
WLSH2_k127_11319858_18 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000003826 239.0
WLSH2_k127_11319858_19 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000006979 199.0
WLSH2_k127_11319858_2 AAA domain - - - 5.588e-215 711.0
WLSH2_k127_11319858_20 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000001992 199.0
WLSH2_k127_11319858_21 AAA domain - - - 0.000000000000000000000000000000000000000444 151.0
WLSH2_k127_11319858_22 Protein conserved in bacteria K09928 - - 0.0000000000000000000000001182 113.0
WLSH2_k127_11319858_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000005272 110.0
WLSH2_k127_11319858_24 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000002977 107.0
WLSH2_k127_11319858_25 AMP binding - - - 0.0000000000000000000001321 108.0
WLSH2_k127_11319858_26 Tetratricopeptide repeat - - - 0.0000000000000000000001984 109.0
WLSH2_k127_11319858_27 Conjugal transfer protein TraD - - - 0.000000000001702 73.0
WLSH2_k127_11319858_28 - K07485 - - 0.0000000001157 63.0
WLSH2_k127_11319858_29 AAA domain K07133 - - 0.00000000421 60.0
WLSH2_k127_11319858_3 Cation transporter/ATPase, N-terminus - - - 5.936e-212 688.0
WLSH2_k127_11319858_30 Transcriptional regulator - - - 0.0004929 49.0
WLSH2_k127_11319858_4 ABC transporter, ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 576.0
WLSH2_k127_11319858_5 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 441.0
WLSH2_k127_11319858_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 430.0
WLSH2_k127_11319858_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 400.0
WLSH2_k127_11319858_8 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 379.0
WLSH2_k127_11319858_9 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 377.0
WLSH2_k127_11451104_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.239e-226 723.0
WLSH2_k127_11451104_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 520.0
WLSH2_k127_11451104_10 PFAM transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002711 248.0
WLSH2_k127_11451104_11 PFAM transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000001317 195.0
WLSH2_k127_11451104_12 - - - - 0.000000000000000000000000000000000000000000000006067 173.0
WLSH2_k127_11451104_13 carbohydrate metabolic process K09798 - - 0.00000000000000000000000000000000000000000003513 179.0
WLSH2_k127_11451104_14 IS66 Orf2 like protein - - - 0.000000000000000000000000000000000000003472 154.0
WLSH2_k127_11451104_15 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000006687 145.0
WLSH2_k127_11451104_16 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.00000000000000000000000000000007383 126.0
WLSH2_k127_11451104_17 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.0000000000001938 73.0
WLSH2_k127_11451104_18 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000146 65.0
WLSH2_k127_11451104_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 490.0
WLSH2_k127_11451104_21 - - - - 0.0006758 48.0
WLSH2_k127_11451104_3 ATPase domain predominantly from Archaea K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 449.0
WLSH2_k127_11451104_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 404.0
WLSH2_k127_11451104_5 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
WLSH2_k127_11451104_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 344.0
WLSH2_k127_11451104_7 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 333.0
WLSH2_k127_11451104_8 hmm pf01612 K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
WLSH2_k127_11451104_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
WLSH2_k127_1252386_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
WLSH2_k127_1252386_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 396.0
WLSH2_k127_1252386_2 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000009483 166.0
WLSH2_k127_1269271_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 9.114e-267 841.0
WLSH2_k127_1269271_1 ATPase domain predominantly from Archaea K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 563.0
WLSH2_k127_1269271_2 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 562.0
WLSH2_k127_1269271_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 517.0
WLSH2_k127_1269271_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 507.0
WLSH2_k127_1269271_5 Bacterial transferase hexapeptide (six repeats) K00638 - 2.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 333.0
WLSH2_k127_1269271_6 Bacterial transcription activator, effector binding domain - - - 0.000000000000000000000000000000000000000000000000000001795 195.0
WLSH2_k127_1269271_7 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000002918 147.0
WLSH2_k127_1269271_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000001795 109.0
WLSH2_k127_1432414_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.719e-253 792.0
WLSH2_k127_1432414_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 606.0
WLSH2_k127_1432414_2 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 424.0
WLSH2_k127_1432414_3 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
WLSH2_k127_1432414_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 327.0
WLSH2_k127_1432414_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000002537 126.0
WLSH2_k127_1432414_6 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000004053 110.0
WLSH2_k127_1432414_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002048 79.0
WLSH2_k127_1432414_8 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000008232 58.0
WLSH2_k127_1432414_9 Protein of unknown function (DUF559) - - - 0.0002559 44.0
WLSH2_k127_1447716_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.172e-306 945.0
WLSH2_k127_1447716_1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 2.235e-228 714.0
WLSH2_k127_1447716_10 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 250.0
WLSH2_k127_1447716_11 ERAD pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000006545 265.0
WLSH2_k127_1447716_12 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000002463 217.0
WLSH2_k127_1447716_13 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000003317 185.0
WLSH2_k127_1447716_14 - - - - 0.000000000000000000000000000000000000000000000002838 181.0
WLSH2_k127_1447716_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000322 170.0
WLSH2_k127_1447716_16 regulation of response to stimulus K19613 - - 0.0000000000000000000000000000000000000157 158.0
WLSH2_k127_1447716_17 Sel1-like repeats. K07126 - - 0.00000000000000001299 98.0
WLSH2_k127_1447716_18 Domain of unknown function - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005886,GO:0012505,GO:0016020,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000593 97.0
WLSH2_k127_1447716_19 ERAD pathway - - - 0.000000000001376 82.0
WLSH2_k127_1447716_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.879e-226 710.0
WLSH2_k127_1447716_20 Transposase IS66 family K07484 - - 0.0000008066 51.0
WLSH2_k127_1447716_21 Sel1-like repeats. K07126 - - 0.000004048 61.0
WLSH2_k127_1447716_23 Lipase (class 3) - - - 0.0002993 55.0
WLSH2_k127_1447716_3 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 604.0
WLSH2_k127_1447716_4 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 542.0
WLSH2_k127_1447716_5 Branched-chain amino acid transport protein K03311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 493.0
WLSH2_k127_1447716_6 Surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 491.0
WLSH2_k127_1447716_7 TamB, inner membrane protein subunit of TAM complex - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 494.0
WLSH2_k127_1447716_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 335.0
WLSH2_k127_1447716_9 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
WLSH2_k127_1449565_0 Heat shock 70 kDa protein K04043 - - 0.0 1016.0
WLSH2_k127_1449565_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 489.0
WLSH2_k127_1449565_10 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000001848 156.0
WLSH2_k127_1449565_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000002144 144.0
WLSH2_k127_1449565_12 Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 K16643 GO:0000003,GO:0001558,GO:0002028,GO:0003006,GO:0003008,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005102,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006950,GO:0006996,GO:0007162,GO:0007275,GO:0007320,GO:0007399,GO:0007417,GO:0007420,GO:0007565,GO:0007566,GO:0007596,GO:0007599,GO:0007600,GO:0007610,GO:0007617,GO:0007618,GO:0007620,GO:0008150,GO:0008201,GO:0008285,GO:0008589,GO:0009314,GO:0009581,GO:0009582,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009888,GO:0009892,GO:0009894,GO:0009895,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010256,GO:0010466,GO:0010468,GO:0010543,GO:0010544,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010755,GO:0010757,GO:0010766,GO:0010951,GO:0010955,GO:0010959,GO:0010975,GO:0010976,GO:0012505,GO:0014013,GO:0014015,GO:0014066,GO:0014067,GO:0016020,GO:0016043,GO:0016050,GO:0019098,GO:0019222,GO:0019897,GO:0019898,GO:0019953,GO:0021549,GO:0021575,GO:0021587,GO:0021675,GO:0021681,GO:0021683,GO:0021695,GO:0021696,GO:0022008,GO:0022037,GO:0022407,GO:0022408,GO:0022414,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030193,GO:0030195,GO:0030234,GO:0030308,GO:0030334,GO:0030414,GO:0030902,GO:0031012,GO:0031091,GO:0031232,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031410,GO:0031594,GO:0031982,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032940,GO:0033363,GO:0034110,GO:0034111,GO:0035295,GO:0036477,GO:0040008,GO:0040012,GO:0040034,GO:0042060,GO:0042127,GO:0042176,GO:0042177,GO:0042628,GO:0043025,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043269,GO:0043271,GO:0044085,GO:0044092,GO:0044297,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0045202,GO:0045297,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045685,GO:0045687,GO:0045861,GO:0045879,GO:0045926,GO:0046903,GO:0048167,GO:0048505,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048608,GO:0048609,GO:0048699,GO:0048710,GO:0048711,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050804,GO:0050806,GO:0050817,GO:0050818,GO:0050819,GO:0050865,GO:0050866,GO:0050877,GO:0050878,GO:0050896,GO:0050906,GO:0050954,GO:0050974,GO:0050982,GO:0051049,GO:0051051,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051336,GO:0051346,GO:0051606,GO:0051704,GO:0051960,GO:0051962,GO:0051966,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060384,GO:0060429,GO:0061041,GO:0061045,GO:0061107,GO:0061108,GO:0061110,GO:0061134,GO:0061135,GO:0061458,GO:0062023,GO:0065007,GO:0065008,GO:0065009,GO:0070613,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0090330,GO:0090331,GO:0097367,GO:0097458,GO:0097708,GO:0098552,GO:0098772,GO:0099177,GO:0099503,GO:0120035,GO:1900046,GO:1900047,GO:1901681,GO:1902531,GO:1902532,GO:1903034,GO:1903035,GO:1903317,GO:1903318,GO:2000026,GO:2000145 - 0.00000000000000007176 93.0
WLSH2_k127_1449565_14 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000002084 67.0
WLSH2_k127_1449565_15 - - - - 0.000249 53.0
WLSH2_k127_1449565_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 458.0
WLSH2_k127_1449565_3 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 350.0
WLSH2_k127_1449565_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 326.0
WLSH2_k127_1449565_5 NLPA lipoprotein K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 304.0
WLSH2_k127_1449565_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000009154 233.0
WLSH2_k127_1449565_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000471 183.0
WLSH2_k127_1449565_8 ATPase domain predominantly from Archaea K06921 - - 0.00000000000000000000000000000000000000000000004299 173.0
WLSH2_k127_1449565_9 Ion transport protein K08714 - - 0.0000000000000000000000000000000000000000006018 169.0
WLSH2_k127_1499747_0 ImcF-related N-terminal domain K11891 - - 0.0 1724.0
WLSH2_k127_1499747_1 AMP-binding enzyme K01907 - 6.2.1.16 1.652e-279 873.0
WLSH2_k127_1499747_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004029 271.0
WLSH2_k127_1499747_11 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
WLSH2_k127_1499747_12 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000355 262.0
WLSH2_k127_1499747_13 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000147 259.0
WLSH2_k127_1499747_14 YheO-like PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
WLSH2_k127_1499747_15 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000002174 208.0
WLSH2_k127_1499747_16 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.0000000000000000000000000000000008315 132.0
WLSH2_k127_1499747_17 Domain of unknown function (DUF4280) - - - 0.0000000000000000006451 90.0
WLSH2_k127_1499747_18 Leucine rich repeat containing 39 - GO:0003007,GO:0003008,GO:0003013,GO:0003015,GO:0006996,GO:0007010,GO:0007275,GO:0007507,GO:0007517,GO:0008015,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010927,GO:0014706,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0031032,GO:0032501,GO:0032502,GO:0032989,GO:0042692,GO:0044085,GO:0045214,GO:0048468,GO:0048513,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0055008,GO:0060047,GO:0060415,GO:0060537,GO:0061061,GO:0070925,GO:0071840,GO:0072359,GO:0097435 - 0.00000000000001317 81.0
WLSH2_k127_1499747_19 - - - - 0.00000000000001805 86.0
WLSH2_k127_1499747_2 RmuC family K09760 - - 2.261e-221 697.0
WLSH2_k127_1499747_20 DDE superfamily endonuclease - - - 0.00005401 46.0
WLSH2_k127_1499747_3 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 582.0
WLSH2_k127_1499747_4 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 517.0
WLSH2_k127_1499747_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 472.0
WLSH2_k127_1499747_6 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 386.0
WLSH2_k127_1499747_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 380.0
WLSH2_k127_1499747_8 Type VI secretion system protein DotU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 301.0
WLSH2_k127_1499747_9 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 301.0
WLSH2_k127_1501148_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1284.0
WLSH2_k127_1501148_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.406e-221 702.0
WLSH2_k127_1501148_10 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000007634 222.0
WLSH2_k127_1501148_11 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000007888 138.0
WLSH2_k127_1501148_12 ribosomal protein S21 K02970 - - 0.00000000000000000000000000001223 118.0
WLSH2_k127_1501148_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K00384 - 1.8.1.9 0.000000000000000000002222 99.0
WLSH2_k127_1501148_14 - - - - 0.0000000000000001119 80.0
WLSH2_k127_1501148_15 Zinc-finger domain - - - 0.000000000000001426 78.0
WLSH2_k127_1501148_17 Leucine Rich repeat - - - 0.000000004335 68.0
WLSH2_k127_1501148_18 Protein of unknown function (DUF1778) - - - 0.00000004477 57.0
WLSH2_k127_1501148_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 441.0
WLSH2_k127_1501148_3 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 433.0
WLSH2_k127_1501148_4 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 387.0
WLSH2_k127_1501148_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 380.0
WLSH2_k127_1501148_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
WLSH2_k127_1501148_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 335.0
WLSH2_k127_1501148_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003473 288.0
WLSH2_k127_1501148_9 TIGRFAM outer membrane adhesin like proteiin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001145 300.0
WLSH2_k127_1507486_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 607.0
WLSH2_k127_1507486_1 3-hydroxyacyl-CoA dehydrogenase K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 404.0
WLSH2_k127_1877122_0 ABC transporter transmembrane region K06147 - - 2.027e-256 803.0
WLSH2_k127_1877122_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 616.0
WLSH2_k127_1877122_10 Ion transport protein K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000003261 244.0
WLSH2_k127_1877122_11 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000005925 224.0
WLSH2_k127_1877122_12 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000004097 207.0
WLSH2_k127_1877122_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000002906 139.0
WLSH2_k127_1877122_14 - - - - 0.000000000000000000000000000001146 129.0
WLSH2_k127_1877122_15 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000006894 117.0
WLSH2_k127_1877122_16 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000003906 91.0
WLSH2_k127_1877122_17 ATP-dependent peptidase activity K07452 - - 0.00000005891 65.0
WLSH2_k127_1877122_18 spectrin binding - - - 0.0000058 54.0
WLSH2_k127_1877122_19 PFAM PEBP family protein K06910 - - 0.000008183 49.0
WLSH2_k127_1877122_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 545.0
WLSH2_k127_1877122_20 Acyl CoA binding protein - GO:0002039,GO:0003674,GO:0005070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006810,GO:0006839,GO:0006915,GO:0006996,GO:0007005,GO:0007006,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008219,GO:0009966,GO:0009967,GO:0009987,GO:0010638,GO:0010646,GO:0010647,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0012501,GO:0016043,GO:0023051,GO:0023052,GO:0023056,GO:0030054,GO:0030674,GO:0031974,GO:0031981,GO:0032879,GO:0032880,GO:0033043,GO:0035556,GO:0035591,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045786,GO:0046902,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051059,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051716,GO:0051726,GO:0060090,GO:0060341,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0071840,GO:0072331,GO:0072332,GO:0090559,GO:0097190,GO:0097193,GO:1900117,GO:1900119,GO:1900739,GO:1900740,GO:1901028,GO:1901030,GO:1901796,GO:1902531,GO:1903747,GO:1903749,GO:1903827,GO:1903829,GO:1904951,GO:1905475,GO:1905477,GO:2001233,GO:2001235 - 0.00004321 58.0
WLSH2_k127_1877122_3 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 461.0
WLSH2_k127_1877122_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 380.0
WLSH2_k127_1877122_5 Ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 363.0
WLSH2_k127_1877122_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001022 263.0
WLSH2_k127_1877122_7 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006965 261.0
WLSH2_k127_1877122_8 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 252.0
WLSH2_k127_1877122_9 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
WLSH2_k127_1890325_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 394.0
WLSH2_k127_1890325_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 302.0
WLSH2_k127_1890325_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000001597 218.0
WLSH2_k127_1890574_0 peptidase S9 K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 553.0
WLSH2_k127_1890574_1 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 424.0
WLSH2_k127_1890574_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001947 245.0
WLSH2_k127_1890574_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00001206 47.0
WLSH2_k127_1890574_4 Transposase - - - 0.0008007 44.0
WLSH2_k127_1919535_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004651 216.0
WLSH2_k127_1919535_1 NUDIX domain - - - 0.0000000000000000000000000002691 119.0
WLSH2_k127_1919535_2 GrpB protein - - - 0.0000000000003019 70.0
WLSH2_k127_2020611_0 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 1.22e-280 881.0
WLSH2_k127_2020611_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 1.028e-227 713.0
WLSH2_k127_2020611_10 transferase activity, transferring glycosyl groups K12993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001814 314.0
WLSH2_k127_2020611_12 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000000000000002231 124.0
WLSH2_k127_2020611_13 Bacteriophage replication gene A protein (GPA) - - - 0.00000000001125 66.0
WLSH2_k127_2020611_2 methyltransferase FkbM family - - - 5.43e-204 700.0
WLSH2_k127_2020611_3 Belongs to the mannose-6-phosphate isomerase type 2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 610.0
WLSH2_k127_2020611_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 515.0
WLSH2_k127_2020611_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 512.0
WLSH2_k127_2020611_6 ABC transporter K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 484.0
WLSH2_k127_2020611_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 404.0
WLSH2_k127_2020611_8 Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 357.0
WLSH2_k127_2020611_9 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 317.0
WLSH2_k127_2193765_0 ABC transporter K02010,K11076 - 3.6.3.30 5.421e-202 634.0
WLSH2_k127_2193765_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 449.0
WLSH2_k127_2193765_10 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000003222 168.0
WLSH2_k127_2193765_11 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000007654 158.0
WLSH2_k127_2193765_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000005299 119.0
WLSH2_k127_2193765_2 Binding-protein-dependent transport system inner membrane component K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 437.0
WLSH2_k127_2193765_3 Binding-protein-dependent transport system inner membrane component K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 405.0
WLSH2_k127_2193765_4 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 315.0
WLSH2_k127_2193765_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004637 227.0
WLSH2_k127_2193765_6 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001962 224.0
WLSH2_k127_2193765_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000003482 225.0
WLSH2_k127_2193765_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000002202 209.0
WLSH2_k127_2193765_9 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000002418 181.0
WLSH2_k127_2237152_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1297.0
WLSH2_k127_2237152_1 cation ABC transporter, periplasmic cation-binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 321.0
WLSH2_k127_2237152_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 283.0
WLSH2_k127_2237152_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
WLSH2_k127_2237152_4 Domain of unknown function (DUF3576) - - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
WLSH2_k127_2237152_5 - - - - 0.0000000000000000000000000000000000000000000002632 170.0
WLSH2_k127_2237152_6 - K03643 - - 0.0000000000000000000000000000005432 127.0
WLSH2_k127_2239654_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.62e-301 940.0
WLSH2_k127_2239654_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 400.0
WLSH2_k127_2239654_10 Hypoxia induced protein conserved region - - - 0.000000000000000000006758 93.0
WLSH2_k127_2239654_11 Phosphotransferase enzyme family - - - 0.000000000000000000008812 105.0
WLSH2_k127_2239654_12 Leucine-rich repeat (LRR) protein - - - 0.0000001368 61.0
WLSH2_k127_2239654_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 371.0
WLSH2_k127_2239654_3 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 353.0
WLSH2_k127_2239654_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 361.0
WLSH2_k127_2239654_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 340.0
WLSH2_k127_2239654_6 glutamine amidotransferases K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 319.0
WLSH2_k127_2239654_7 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 308.0
WLSH2_k127_2239654_8 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001092 249.0
WLSH2_k127_2239654_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000002089 179.0
WLSH2_k127_2272755_0 helicase K08282 - 2.7.11.1 1.735e-282 897.0
WLSH2_k127_2272755_1 2-Nitropropane dioxygenase - - - 2.613e-249 775.0
WLSH2_k127_2272755_10 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 289.0
WLSH2_k127_2272755_11 protein secretion K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001275 287.0
WLSH2_k127_2272755_12 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001656 272.0
WLSH2_k127_2272755_13 SpoU rRNA Methylase family K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000001167 207.0
WLSH2_k127_2272755_14 - - - - 0.000000000000000000128 102.0
WLSH2_k127_2272755_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 497.0
WLSH2_k127_2272755_3 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 490.0
WLSH2_k127_2272755_4 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 430.0
WLSH2_k127_2272755_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 425.0
WLSH2_k127_2272755_6 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 368.0
WLSH2_k127_2272755_7 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 346.0
WLSH2_k127_2272755_8 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 342.0
WLSH2_k127_2272755_9 Ankyrin repeat K15503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 339.0
WLSH2_k127_2273103_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 550.0
WLSH2_k127_2273103_1 Biopolymer transport K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 369.0
WLSH2_k127_2273103_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 301.0
WLSH2_k127_2273103_3 domain, Protein K01674,K03646 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003756 255.0
WLSH2_k127_2273103_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000000000000000009327 205.0
WLSH2_k127_2382976_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1357.0
WLSH2_k127_2382976_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
WLSH2_k127_2382976_2 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000000000002846 195.0
WLSH2_k127_2382976_3 PFAM Patatin-like phospholipase - - - 0.0000000000000000000000000000009763 139.0
WLSH2_k127_2684554_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 8.393e-306 958.0
WLSH2_k127_2684554_1 Carboxyl transferase domain K01969 - 6.4.1.4 6.008e-284 878.0
WLSH2_k127_2684554_2 3-phosphoshikimate 1-carboxyvinyltransferase K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 555.0
WLSH2_k127_2684554_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006694 238.0
WLSH2_k127_2684554_4 Pyrroline-5-carboxylate reductase dimerisation K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000001108 216.0
WLSH2_k127_2684554_5 Leucine-rich repeats, outliers - - - 0.000000000000367 81.0
WLSH2_k127_2696290_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.563e-275 853.0
WLSH2_k127_2696290_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000005405 147.0
WLSH2_k127_2696290_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0008483 42.0
WLSH2_k127_2974300_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 595.0
WLSH2_k127_2974300_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 553.0
WLSH2_k127_2974300_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 458.0
WLSH2_k127_2974300_3 HemY domain protein K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 335.0
WLSH2_k127_2974300_4 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 301.0
WLSH2_k127_2974300_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000002868 259.0
WLSH2_k127_2974300_6 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000003978 214.0
WLSH2_k127_2974300_7 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000001339 211.0
WLSH2_k127_2974300_8 Transposase - - - 0.0000004463 52.0
WLSH2_k127_2995694_0 TraG-like protein, N-terminal region K12056 - - 3.721e-289 914.0
WLSH2_k127_2995694_1 F pilus assembly Type-IV secretion system for plasmid transfer K12063 - - 1.856e-218 705.0
WLSH2_k127_2995694_10 Bacterial conjugation TrbI-like protein K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 316.0
WLSH2_k127_2995694_11 F plasmid transfer operon protein K12057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 295.0
WLSH2_k127_2995694_12 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001073 244.0
WLSH2_k127_2995694_13 phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001167 241.0
WLSH2_k127_2995694_14 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.000000000000000000000000000000000000000000000000000000000364 207.0
WLSH2_k127_2995694_15 TraE protein K12067 - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
WLSH2_k127_2995694_16 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000001032 198.0
WLSH2_k127_2995694_17 Conjugal transfer protein TraW K12061 - - 0.000000000000000000000000000000000000000000000397 173.0
WLSH2_k127_2995694_18 acetyltransferase - - - 0.0000000000000000000000000000000000000000005612 161.0
WLSH2_k127_2995694_19 TraK protein - - - 0.0000000000000000000000000000000000000006336 157.0
WLSH2_k127_2995694_2 Type IV secretory system Conjugative DNA transfer - - - 1.067e-197 632.0
WLSH2_k127_2995694_20 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000001249 140.0
WLSH2_k127_2995694_21 Signal peptidase, peptidase S26 K12062 - - 0.00000000000000000000000000000004077 132.0
WLSH2_k127_2995694_22 Methyltransferase domain - - - 0.000000000000000000000000005922 122.0
WLSH2_k127_2995694_23 Replication initiation and membrane attachment - - - 0.00000000000000000000000005764 123.0
WLSH2_k127_2995694_24 LysE type translocator - - - 0.0000000000000000000000001414 113.0
WLSH2_k127_2995694_25 methyltransferase K04791 - - 0.0000000000000000000000003084 117.0
WLSH2_k127_2995694_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000199 103.0
WLSH2_k127_2995694_27 TraL protein K12068 - - 0.000000000000000000000209 100.0
WLSH2_k127_2995694_28 Type-F conjugative transfer system pilin assembly protein K12059 - - 0.000000000000000000001718 101.0
WLSH2_k127_2995694_3 Conjugative relaxosome accessory transposon protein K12072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 601.0
WLSH2_k127_2995694_30 Transcriptional regulator - - - 0.0000000000000001699 81.0
WLSH2_k127_2995694_31 Protein of unknwon function (DUF3310) - - - 0.000000000000001626 83.0
WLSH2_k127_2995694_33 Transcriptional regulator - - - 0.000000000005402 77.0
WLSH2_k127_2995694_34 Cro/C1-type HTH DNA-binding domain - - - 0.00000000001468 72.0
WLSH2_k127_2995694_36 Acetyltransferase (GNAT) domain - - - 0.000000008829 64.0
WLSH2_k127_2995694_37 acetyltransferase - - - 0.00000001204 63.0
WLSH2_k127_2995694_4 TraU protein K12060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 507.0
WLSH2_k127_2995694_5 Type-1V conjugative transfer system mating pair stabilisation K12058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 452.0
WLSH2_k127_2995694_6 Choline/ethanolamine kinase K18844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 434.0
WLSH2_k127_2995694_7 peptidase S66 K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 378.0
WLSH2_k127_2995694_8 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 368.0
WLSH2_k127_2995694_9 Aminoglycoside/hydroxyurea antibiotic resistance kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 319.0
WLSH2_k127_30055_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1430.0
WLSH2_k127_30055_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.677e-260 817.0
WLSH2_k127_30055_10 DnaJ central domain K09503 - - 0.0009521 49.0
WLSH2_k127_30055_2 Cytochrome c-type biogenesis protein ccmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 581.0
WLSH2_k127_30055_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 367.0
WLSH2_k127_30055_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
WLSH2_k127_30055_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
WLSH2_k127_30055_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000002744 222.0
WLSH2_k127_30055_7 Belongs to the WrbA family - - - 0.000000000000000000000000000000000000000000000000000000001283 206.0
WLSH2_k127_30055_9 Belongs to the peptidase S8 family K14743 - - 0.000000001164 71.0
WLSH2_k127_3018623_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.706e-204 642.0
WLSH2_k127_3018623_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 443.0
WLSH2_k127_3018623_2 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 379.0
WLSH2_k127_3018623_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 231.0
WLSH2_k127_3018623_4 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000006544 187.0
WLSH2_k127_3018623_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000001258 170.0
WLSH2_k127_3018623_6 ATPase activator activity K04082,K05801 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.0000000000000000000000000003573 121.0
WLSH2_k127_3018623_7 MotA/TolQ/ExbB proton channel family K02556 - - 0.000001333 49.0
WLSH2_k127_3125491_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
WLSH2_k127_3125491_1 - - - - 0.000000000000000000000000000000000000000000000000000000001126 220.0
WLSH2_k127_3186500_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1360.0
WLSH2_k127_3186500_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 1.229e-213 671.0
WLSH2_k127_3186500_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 504.0
WLSH2_k127_3186500_3 Ankyrin repeat K15503 - - 0.000000000000000000000000001509 121.0
WLSH2_k127_3186500_4 Sel1-like repeats. K15475 - - 0.000000000001235 81.0
WLSH2_k127_3189011_0 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 586.0
WLSH2_k127_3189011_1 ABC-type metal ion transport system permease component K02072 - - 0.0000000000000000001947 88.0
WLSH2_k127_3197872_0 Amino acid adenylation domain - - - 9.02e-277 898.0
WLSH2_k127_3197872_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.006e-225 707.0
WLSH2_k127_3197872_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.29e-197 621.0
WLSH2_k127_3197872_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 475.0
WLSH2_k127_3197872_4 - - - - 0.0000000000000000000000000000000000000000000000082 179.0
WLSH2_k127_3197872_5 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000001299 112.0
WLSH2_k127_3230002_0 Aldehyde dehydrogenase family - - - 4.271e-241 754.0
WLSH2_k127_3230002_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 537.0
WLSH2_k127_3230002_10 regulation of response to stimulus - - - 0.00000000000000000000000000352 125.0
WLSH2_k127_3230002_11 Helix-turn-helix K07726 - - 0.00000000000000000000000004785 111.0
WLSH2_k127_3230002_12 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000007999 110.0
WLSH2_k127_3230002_13 Leucine-rich repeat protein K19613 GO:0000164,GO:0002119,GO:0002164,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007264,GO:0007265,GO:0007275,GO:0007517,GO:0008150,GO:0008157,GO:0008287,GO:0008543,GO:0009719,GO:0009791,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010646,GO:0010647,GO:0010921,GO:0016020,GO:0017016,GO:0019208,GO:0019220,GO:0019222,GO:0019888,GO:0019899,GO:0019902,GO:0019903,GO:0023051,GO:0023052,GO:0023056,GO:0030234,GO:0031267,GO:0031323,GO:0031344,GO:0031399,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032991,GO:0035303,GO:0035304,GO:0035556,GO:0040025,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043666,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046578,GO:0046579,GO:0048513,GO:0048518,GO:0048522,GO:0048569,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051020,GO:0051056,GO:0051057,GO:0051128,GO:0051171,GO:0051174,GO:0051246,GO:0051336,GO:0051716,GO:0060255,GO:0061061,GO:0065007,GO:0065009,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071774,GO:0071944,GO:0080090,GO:0098772,GO:1902494,GO:1902531,GO:1902533,GO:1903293 - 0.000000000000000000000000148 119.0
WLSH2_k127_3230002_14 PFAM Acetyltransferase (GNAT) family K03789 - 2.3.1.128 0.0000000000000007919 85.0
WLSH2_k127_3230002_15 OmpA-like transmembrane domain K03286 - - 0.0007787 50.0
WLSH2_k127_3230002_2 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 528.0
WLSH2_k127_3230002_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
WLSH2_k127_3230002_4 Domain of unknown function (DUF4172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 406.0
WLSH2_k127_3230002_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity) K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
WLSH2_k127_3230002_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001439 232.0
WLSH2_k127_3230002_7 COG2867 oligoketide cyclase lipid transport protein K18588 - - 0.00000000000000000000000000000000000000000000000000000000006199 207.0
WLSH2_k127_3230002_8 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000008015 170.0
WLSH2_k127_3230002_9 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000000000000000000003086 137.0
WLSH2_k127_3239306_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06147 - - 6.098e-197 629.0
WLSH2_k127_3239306_1 Protein of unknown function (DUF1016) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 479.0
WLSH2_k127_3239306_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 306.0
WLSH2_k127_3239306_3 Chloramphenicol phosphotransferase-like protein K18554 - - 0.000000000000000000000000000000000000000000000001231 177.0
WLSH2_k127_3239306_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000002757 173.0
WLSH2_k127_3239306_5 FR47-like protein - - - 0.00000000000000000046 93.0
WLSH2_k127_3239306_6 GrpB protein - - - 0.0000000000001373 71.0
WLSH2_k127_3239306_7 Chloramphenicol phosphotransferase-like protein K18554 - - 0.00000003504 59.0
WLSH2_k127_3239306_8 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0002382 50.0
WLSH2_k127_329047_0 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 303.0
WLSH2_k127_329047_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000108 216.0
WLSH2_k127_329047_2 GrpB protein - - - 0.0000000000000000000000000000000000000000000000000000921 193.0
WLSH2_k127_329047_3 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region K20262 - 1.10.3.16 0.000000000000000000000000000000000000000000000000165 183.0
WLSH2_k127_329047_4 AAA domain - - - 0.0000000000000000000000000000000004175 133.0
WLSH2_k127_3313823_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases - - - 0.0 1525.0
WLSH2_k127_3313823_1 Penicillin-Binding Protein C-terminus Family - - - 9.02e-272 854.0
WLSH2_k127_3313823_10 Transcriptional regulator K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 377.0
WLSH2_k127_3313823_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 323.0
WLSH2_k127_3313823_12 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
WLSH2_k127_3313823_13 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 307.0
WLSH2_k127_3313823_14 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000005519 257.0
WLSH2_k127_3313823_15 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000009308 207.0
WLSH2_k127_3313823_16 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000008403 190.0
WLSH2_k127_3313823_17 Alkylphosphonate utilization protein K06193 - - 0.0000000000000000000000000000000000000000000000001096 179.0
WLSH2_k127_3313823_18 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000001337 171.0
WLSH2_k127_3313823_19 TspO/MBR family K05770 - - 0.000000000000000000000000000000000001114 144.0
WLSH2_k127_3313823_2 ABC transporter C-terminal domain K15738 - - 6.399e-256 801.0
WLSH2_k127_3313823_20 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000419 115.0
WLSH2_k127_3313823_21 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000008606 115.0
WLSH2_k127_3313823_22 Lipid A 3-O-deacylase (PagL) K12976 - - 0.000000000000000000000002101 109.0
WLSH2_k127_3313823_23 PFAM Leucine Rich Repeat K19613 - - 0.000000000000000000000003372 115.0
WLSH2_k127_3313823_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.0000000000000000001943 91.0
WLSH2_k127_3313823_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000004112 77.0
WLSH2_k127_3313823_26 Protein of unknown function (DUF1398) - - - 0.00000000001523 70.0
WLSH2_k127_3313823_27 chromosome segregation - - - 0.0000000002226 73.0
WLSH2_k127_3313823_29 Belongs to the ompA family K03286 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - 0.0001347 52.0
WLSH2_k127_3313823_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.043e-249 786.0
WLSH2_k127_3313823_4 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 544.0
WLSH2_k127_3313823_5 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 522.0
WLSH2_k127_3313823_6 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 437.0
WLSH2_k127_3313823_7 Sugar (and other) transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 420.0
WLSH2_k127_3313823_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 411.0
WLSH2_k127_3313823_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 384.0
WLSH2_k127_3439890_0 SNF2 family N-terminal domain - - - 7.666e-253 821.0
WLSH2_k127_3439890_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 554.0
WLSH2_k127_3439890_10 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001424 275.0
WLSH2_k127_3439890_11 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000000000000000000000006167 166.0
WLSH2_k127_3439890_12 Ubiquinol-cytochrome C chaperone - - - 0.00000000000000000000000000000000000004567 150.0
WLSH2_k127_3439890_13 Uncharacterized ACR, COG1399 - - - 0.000000000000000000000000000003363 128.0
WLSH2_k127_3439890_14 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000003444 105.0
WLSH2_k127_3439890_15 - - - - 0.00000000000001351 79.0
WLSH2_k127_3439890_16 Flavinator of succinate dehydrogenase - - - 0.000000000005317 68.0
WLSH2_k127_3439890_17 riboflavin kinase activity K11753 - 2.7.1.26,2.7.7.2 0.0000000000503 70.0
WLSH2_k127_3439890_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 501.0
WLSH2_k127_3439890_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 482.0
WLSH2_k127_3439890_4 Transmembrane amino acid transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 458.0
WLSH2_k127_3439890_5 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 430.0
WLSH2_k127_3439890_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 410.0
WLSH2_k127_3439890_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 391.0
WLSH2_k127_3439890_8 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 301.0
WLSH2_k127_3439890_9 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002468 285.0
WLSH2_k127_3581636_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.106e-281 872.0
WLSH2_k127_3581636_1 Terminase RNaseH-like domain - - - 1.117e-216 679.0
WLSH2_k127_3581636_2 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 515.0
WLSH2_k127_3581636_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 355.0
WLSH2_k127_3581636_4 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 344.0
WLSH2_k127_3581636_6 interleukin-8 biosynthetic process - - - 0.00000000000000003854 94.0
WLSH2_k127_3581636_7 - - - - 0.0000000001882 69.0
WLSH2_k127_3581636_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000008031 66.0
WLSH2_k127_3909915_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 5.4e-323 993.0
WLSH2_k127_3909915_1 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 3.997e-219 694.0
WLSH2_k127_3909915_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 598.0
WLSH2_k127_3909915_3 ABC transporter, permease protein K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 377.0
WLSH2_k127_3909915_4 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000000001324 201.0
WLSH2_k127_3909915_5 Leucine rich repeat containing 34 - - - 0.0001492 55.0
WLSH2_k127_3943768_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 516.0
WLSH2_k127_3943768_1 GIY-YIG type nucleases (URI domain) K07461 - - 0.00000000000000000000000000000007862 126.0
WLSH2_k127_4386031_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 1.564e-194 611.0
WLSH2_k127_4386031_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 486.0
WLSH2_k127_4386031_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 464.0
WLSH2_k127_4386031_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 343.0
WLSH2_k127_4386031_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000001007 110.0
WLSH2_k127_4386031_5 spectrin binding K15502,K15503 - - 0.00001898 55.0
WLSH2_k127_4408240_0 transport system, ATPase component K05833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 326.0
WLSH2_k127_4408240_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 308.0
WLSH2_k127_4408240_2 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 300.0
WLSH2_k127_4408240_3 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007481 288.0
WLSH2_k127_4408240_4 - - - - 0.0006317 43.0
WLSH2_k127_4570427_0 impB/mucB/samB family K03502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 463.0
WLSH2_k127_4570427_1 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 354.0
WLSH2_k127_4570427_2 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000000001275 214.0
WLSH2_k127_4570427_3 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000006494 188.0
WLSH2_k127_4570427_4 Recombinase zinc beta ribbon domain - - - 0.0000000557 56.0
WLSH2_k127_4612458_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.508e-282 874.0
WLSH2_k127_4612458_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.065e-215 693.0
WLSH2_k127_4612458_10 - - - - 0.0000872 50.0
WLSH2_k127_4612458_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 456.0
WLSH2_k127_4612458_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 397.0
WLSH2_k127_4612458_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000001203 226.0
WLSH2_k127_4612458_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000292 217.0
WLSH2_k127_4612458_6 - - - - 0.0000000000000000000000000000000000000000000000000005056 197.0
WLSH2_k127_4612458_7 Involved in protein export. Participates in an early event of protein translocation (By similarity) K03075 - - 0.0000000000000000000004948 98.0
WLSH2_k127_4612458_8 regulation of response to stimulus K01768,K19613 GO:0001501,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0002761,GO:0002762,GO:0005575,GO:0005576,GO:0005615,GO:0007275,GO:0008150,GO:0009888,GO:0032501,GO:0032502,GO:0044421,GO:0045595,GO:0045596,GO:0045637,GO:0045638,GO:0045670,GO:0045671,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048539,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051241,GO:0060348,GO:0065007,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:2000026 4.6.1.1 0.00000000000000000002542 101.0
WLSH2_k127_4612458_9 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000001413 95.0
WLSH2_k127_4639320_0 Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism K03301 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 2.331e-209 662.0
WLSH2_k127_4639320_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
WLSH2_k127_4643225_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1137.0
WLSH2_k127_4643225_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.291e-261 814.0
WLSH2_k127_4643225_10 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000001514 201.0
WLSH2_k127_4643225_11 - - - - 0.0000000000000000000000000004044 115.0
WLSH2_k127_4643225_12 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000004891 118.0
WLSH2_k127_4643225_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000005885 107.0
WLSH2_k127_4643225_15 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000004084 101.0
WLSH2_k127_4643225_16 SnoaL-like domain - - - 0.000000000000000000001089 101.0
WLSH2_k127_4643225_17 COG4520 Surface antigen - - - 0.00000000000000008165 85.0
WLSH2_k127_4643225_18 - - - - 0.000002302 55.0
WLSH2_k127_4643225_19 - - - - 0.000004944 54.0
WLSH2_k127_4643225_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.879e-247 769.0
WLSH2_k127_4643225_21 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0009778 51.0
WLSH2_k127_4643225_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 477.0
WLSH2_k127_4643225_4 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 470.0
WLSH2_k127_4643225_5 Sugar fermentation stimulation protein homolog K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 308.0
WLSH2_k127_4643225_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003885 277.0
WLSH2_k127_4643225_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
WLSH2_k127_4643225_8 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000876 257.0
WLSH2_k127_4643225_9 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000431 209.0
WLSH2_k127_4665941_0 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
WLSH2_k127_4665941_1 PFAM TPR repeat-containing protein K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002098 257.0
WLSH2_k127_4665941_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
WLSH2_k127_4665941_3 transmembrane transport K01992 - - 0.000000000000000000000000000000001836 135.0
WLSH2_k127_4665941_4 Protein of unknown function (DUF763) K09003 - - 0.000000000001239 70.0
WLSH2_k127_4665941_5 RNase LS, bacterial toxin - - - 0.00000005062 64.0
WLSH2_k127_4719128_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.745e-202 647.0
WLSH2_k127_4719128_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000005062 70.0
WLSH2_k127_4827228_0 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
WLSH2_k127_4827228_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000003352 173.0
WLSH2_k127_4877798_0 Cell Wall Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
WLSH2_k127_4877798_1 - - - - 0.0000000000000000000000000001251 117.0
WLSH2_k127_4991173_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1037.0
WLSH2_k127_4991173_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.361e-307 948.0
WLSH2_k127_4991173_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001358 277.0
WLSH2_k127_4991173_3 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000223 138.0
WLSH2_k127_4991173_4 Protein of unknown function (DUF2608) - - - 0.000001035 59.0
WLSH2_k127_5044619_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.316e-206 649.0
WLSH2_k127_5044619_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 518.0
WLSH2_k127_5044619_10 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.00000000000000000000000000000000000000000000000000000000000001537 231.0
WLSH2_k127_5044619_11 Domain of unknown function (DUF1287) K09974 - - 0.00000000000000000000000000000000000000000000000000000000005657 210.0
WLSH2_k127_5044619_12 DDE domain - - - 0.000000000000000000000009487 100.0
WLSH2_k127_5044619_13 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000003411 83.0
WLSH2_k127_5044619_14 Histidine phosphatase superfamily (branch 1) K15634 GO:0003674,GO:0003824,GO:0004647,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0070178,GO:0070179,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.4.2.12 0.0000000000008042 78.0
WLSH2_k127_5044619_15 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000005344 55.0
WLSH2_k127_5044619_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 505.0
WLSH2_k127_5044619_3 ATPase domain predominantly from Archaea K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 456.0
WLSH2_k127_5044619_4 D-alanyl-D-alanine carboxypeptidase K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
WLSH2_k127_5044619_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002675 287.0
WLSH2_k127_5044619_6 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001785 278.0
WLSH2_k127_5044619_7 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
WLSH2_k127_5044619_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000003011 235.0
WLSH2_k127_5044619_9 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002674 236.0
WLSH2_k127_5059158_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18989 - - 0.0 1395.0
WLSH2_k127_5059158_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 602.0
WLSH2_k127_5059158_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000001114 207.0
WLSH2_k127_5059158_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000001177 128.0
WLSH2_k127_5059158_12 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000004258 113.0
WLSH2_k127_5059158_13 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000002072 106.0
WLSH2_k127_5059158_15 regulator K18831 - - 0.0000000000000000001012 90.0
WLSH2_k127_5059158_2 reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 529.0
WLSH2_k127_5059158_3 Belongs to the SEDS family. MrdB RodA subfamily K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 519.0
WLSH2_k127_5059158_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 520.0
WLSH2_k127_5059158_5 Peptidase, M16 family K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 429.0
WLSH2_k127_5059158_6 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 389.0
WLSH2_k127_5059158_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 384.0
WLSH2_k127_5059158_8 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 329.0
WLSH2_k127_5059158_9 Penicillin binding protein transpeptidase domain K17838 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000005934 237.0
WLSH2_k127_5059163_0 GTP-binding protein TypA K06207 - - 0.0 1006.0
WLSH2_k127_5059163_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.515e-293 911.0
WLSH2_k127_5059163_10 Enoyl-(Acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 513.0
WLSH2_k127_5059163_11 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 502.0
WLSH2_k127_5059163_12 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 496.0
WLSH2_k127_5059163_13 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 471.0
WLSH2_k127_5059163_14 Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism K03301 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 479.0
WLSH2_k127_5059163_15 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 473.0
WLSH2_k127_5059163_16 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 464.0
WLSH2_k127_5059163_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 450.0
WLSH2_k127_5059163_18 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 472.0
WLSH2_k127_5059163_19 Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide- 1,4'-bisphosphate precursor of lipid A K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 409.0
WLSH2_k127_5059163_2 Poly(3-hydroxyalkanoate) synthetase K03821 - - 1.122e-284 886.0
WLSH2_k127_5059163_20 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 393.0
WLSH2_k127_5059163_21 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 398.0
WLSH2_k127_5059163_22 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
WLSH2_k127_5059163_23 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 370.0
WLSH2_k127_5059163_24 FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 371.0
WLSH2_k127_5059163_25 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 352.0
WLSH2_k127_5059163_26 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
WLSH2_k127_5059163_27 Alpha/beta hydrolase family K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 314.0
WLSH2_k127_5059163_28 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 301.0
WLSH2_k127_5059163_29 metal ion binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
WLSH2_k127_5059163_3 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 7.825e-262 818.0
WLSH2_k127_5059163_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 315.0
WLSH2_k127_5059163_31 Mitochondrial fission ELM1 K07276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 281.0
WLSH2_k127_5059163_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005539 278.0
WLSH2_k127_5059163_33 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001984 256.0
WLSH2_k127_5059163_34 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000001407 237.0
WLSH2_k127_5059163_35 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
WLSH2_k127_5059163_36 Including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000001012 197.0
WLSH2_k127_5059163_37 - - - - 0.000000000000000000000000000000000000000000000000005138 188.0
WLSH2_k127_5059163_38 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000003404 167.0
WLSH2_k127_5059163_39 Cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000004167 161.0
WLSH2_k127_5059163_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.878e-221 694.0
WLSH2_k127_5059163_40 Inositol hexakisphosphate - - - 0.00000000000000000000000000000000000002191 155.0
WLSH2_k127_5059163_41 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000003321 132.0
WLSH2_k127_5059163_42 Inositol hexakisphosphate - - - 0.0000000000000000000000000000000004946 143.0
WLSH2_k127_5059163_43 Inositol hexakisphosphate - - - 0.0000000000000000000000000000000009908 141.0
WLSH2_k127_5059163_44 ATPase domain predominantly from Archaea K06921 - - 0.00000000000000000000000000000006207 126.0
WLSH2_k127_5059163_45 LicD family - - - 0.000000000000000000000000000002 132.0
WLSH2_k127_5059163_46 Inositol hexakisphosphate - - - 0.00000000000000000000000000000714 131.0
WLSH2_k127_5059163_47 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000002156 117.0
WLSH2_k127_5059163_48 COG0711 F0F1-type ATP synthase, subunit b K02109 - - 0.000000000000000000000005214 109.0
WLSH2_k127_5059163_49 - - - - 0.000000000000000001138 93.0
WLSH2_k127_5059163_5 Poly-beta-hydroxybutyrate polymerase K03821 - - 6.974e-211 671.0
WLSH2_k127_5059163_50 Class II flagellar assembly regulator - - - 0.000000000000000002424 91.0
WLSH2_k127_5059163_51 Protein required for attachment to host cells - - - 0.000000000000000003736 89.0
WLSH2_k127_5059163_52 Inositol hexakisphosphate - - - 0.000000000000000006825 95.0
WLSH2_k127_5059163_53 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000004692 85.0
WLSH2_k127_5059163_54 - - - - 0.0000000000000004683 92.0
WLSH2_k127_5059163_55 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000001832 80.0
WLSH2_k127_5059163_56 Cell wall formation K00075 - 1.3.1.98 0.00000000003825 64.0
WLSH2_k127_5059163_58 Protein kinase domain - - - 0.000000004815 67.0
WLSH2_k127_5059163_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 6.708e-202 638.0
WLSH2_k127_5059163_60 C8 K03900,K10955,K13908,K21125,K22020 GO:0005575,GO:0005576 - 0.00000001916 68.0
WLSH2_k127_5059163_61 OmpA-like transmembrane domain K16079 - - 0.0000004924 60.0
WLSH2_k127_5059163_62 - - - - 0.00001962 50.0
WLSH2_k127_5059163_7 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 611.0
WLSH2_k127_5059163_8 phosphomannomutase K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 594.0
WLSH2_k127_5059163_9 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 577.0
WLSH2_k127_5061706_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1109.0
WLSH2_k127_5061706_1 Participates in both transcription termination and antitermination K02600 - - 1.019e-227 716.0
WLSH2_k127_5061706_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000004027 133.0
WLSH2_k127_5061706_11 - - - - 0.000000000000000000000000000005794 136.0
WLSH2_k127_5061706_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000003493 122.0
WLSH2_k127_5061706_13 - - - - 0.0000000000002549 72.0
WLSH2_k127_5061706_14 Evidence 5 No homology to any previously reported sequences - - - 0.000213 46.0
WLSH2_k127_5061706_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 9.561e-205 643.0
WLSH2_k127_5061706_3 fructose-bisphosphate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 467.0
WLSH2_k127_5061706_4 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 381.0
WLSH2_k127_5061706_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 304.0
WLSH2_k127_5061706_6 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000005038 193.0
WLSH2_k127_5061706_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000005461 186.0
WLSH2_k127_5061706_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000003791 179.0
WLSH2_k127_5061706_9 - - - - 0.0000000000000000000000000000000000000003662 158.0
WLSH2_k127_5098174_0 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
WLSH2_k127_5098174_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 376.0
WLSH2_k127_5098174_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005782 267.0
WLSH2_k127_5098174_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000003172 102.0
WLSH2_k127_5129671_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.535e-271 841.0
WLSH2_k127_5129671_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.668e-261 819.0
WLSH2_k127_5129671_10 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 294.0
WLSH2_k127_5129671_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
WLSH2_k127_5129671_12 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000001564 233.0
WLSH2_k127_5129671_13 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000001093 192.0
WLSH2_k127_5129671_14 sequence-specific DNA binding K15539 - - 0.00000000000000000000000000000000000000000000000000008602 200.0
WLSH2_k127_5129671_15 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000001844 184.0
WLSH2_k127_5129671_16 COG1294 Cytochrome bd-type quinol oxidase, subunit 2 K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000003512 188.0
WLSH2_k127_5129671_17 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000004802 159.0
WLSH2_k127_5129671_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000006992 151.0
WLSH2_k127_5129671_19 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000005158 151.0
WLSH2_k127_5129671_2 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.098e-240 765.0
WLSH2_k127_5129671_20 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000003045 139.0
WLSH2_k127_5129671_21 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000005762 140.0
WLSH2_k127_5129671_22 PFAM Patatin-like phospholipase - - - 0.0000000000000000000000002653 121.0
WLSH2_k127_5129671_23 COG3621 Patatin - - - 0.0000000000000000000009312 109.0
WLSH2_k127_5129671_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 465.0
WLSH2_k127_5129671_4 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
WLSH2_k127_5129671_5 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 382.0
WLSH2_k127_5129671_6 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 387.0
WLSH2_k127_5129671_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 372.0
WLSH2_k127_5129671_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 336.0
WLSH2_k127_5129671_9 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 312.0
WLSH2_k127_5233852_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 609.0
WLSH2_k127_5233852_1 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 501.0
WLSH2_k127_5286427_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1086.0
WLSH2_k127_5286427_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 424.0
WLSH2_k127_5286427_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 319.0
WLSH2_k127_5286427_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001497 247.0
WLSH2_k127_5286427_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000004476 178.0
WLSH2_k127_5286427_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity) K06925 - - 0.000000000000000000000000000000000000000002819 159.0
WLSH2_k127_5367537_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 329.0
WLSH2_k127_5367537_1 COG1126 ABC-type polar amino acid transport system, ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 289.0
WLSH2_k127_5367537_2 NUDIX domain K01823 - 5.3.3.2 0.00000000000000000000000000000000001811 144.0
WLSH2_k127_5368693_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.274e-226 709.0
WLSH2_k127_5368693_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 485.0
WLSH2_k127_5368693_10 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001151 248.0
WLSH2_k127_5368693_11 Type II secretion system K02505,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000006675 248.0
WLSH2_k127_5368693_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000005874 190.0
WLSH2_k127_5368693_13 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000002077 175.0
WLSH2_k127_5368693_14 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000001277 168.0
WLSH2_k127_5368693_15 Two component regulator three Y domain protein - - - 0.000000000000000000000000000000000002585 153.0
WLSH2_k127_5368693_16 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000000318 134.0
WLSH2_k127_5368693_17 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000000009121 110.0
WLSH2_k127_5368693_18 Transposase - - - 0.00000000000000000000001286 100.0
WLSH2_k127_5368693_19 - - - - 0.000000001549 64.0
WLSH2_k127_5368693_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 459.0
WLSH2_k127_5368693_20 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000001463 59.0
WLSH2_k127_5368693_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 432.0
WLSH2_k127_5368693_4 KR domain K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 418.0
WLSH2_k127_5368693_5 Type II/IV secretion system protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 397.0
WLSH2_k127_5368693_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 309.0
WLSH2_k127_5368693_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 301.0
WLSH2_k127_5368693_8 protein conserved in bacteria K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
WLSH2_k127_5368693_9 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 261.0
WLSH2_k127_5428954_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1019.0
WLSH2_k127_5428954_1 metallo-beta-lactamase K12574 - - 8.46e-266 828.0
WLSH2_k127_5428954_10 Domain of unknown function (DUF1849) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 321.0
WLSH2_k127_5428954_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
WLSH2_k127_5428954_12 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000287 205.0
WLSH2_k127_5428954_13 COG2927 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000003404 199.0
WLSH2_k127_5428954_14 COG0642 Signal transduction histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000003931 164.0
WLSH2_k127_5428954_15 Inositol hexakisphosphate - - - 0.000000000000000000000000000000000000000001164 168.0
WLSH2_k127_5428954_16 trans-aconitate 2-methyltransferase activity K01935,K02169 - 2.1.1.197,6.3.3.3 0.000000000000000000000000002622 121.0
WLSH2_k127_5428954_17 - K11918 - - 0.00000000000000000000000006376 117.0
WLSH2_k127_5428954_18 Ribbon-helix-helix domain - - - 0.00000000001914 68.0
WLSH2_k127_5428954_19 peptidyl-tyrosine sulfation - - - 0.0000000002338 73.0
WLSH2_k127_5428954_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 6.363e-248 777.0
WLSH2_k127_5428954_20 Dehydrogenase K00382 - 1.8.1.4 0.0000000003574 62.0
WLSH2_k127_5428954_22 - - - - 0.00003853 52.0
WLSH2_k127_5428954_3 Dehydrogenase K00382 - 1.8.1.4 6.135e-230 719.0
WLSH2_k127_5428954_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 1.732e-196 625.0
WLSH2_k127_5428954_5 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 529.0
WLSH2_k127_5428954_6 Sugar (and other) transporter K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 470.0
WLSH2_k127_5428954_7 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 471.0
WLSH2_k127_5428954_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 365.0
WLSH2_k127_5428954_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 313.0
WLSH2_k127_5579978_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.225e-236 746.0
WLSH2_k127_5579978_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 566.0
WLSH2_k127_5579978_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 515.0
WLSH2_k127_5579978_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 367.0
WLSH2_k127_5579978_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 366.0
WLSH2_k127_5579978_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000001324 160.0
WLSH2_k127_5579978_6 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000008512 134.0
WLSH2_k127_5579978_7 Acetyltransferase (GNAT) domain - - - 0.00000000001591 74.0
WLSH2_k127_5579978_8 - - - - 0.000000005022 69.0
WLSH2_k127_5579978_9 chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0001312 47.0
WLSH2_k127_5583332_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.259e-317 985.0
WLSH2_k127_5583332_1 Histidine kinase - - - 1.933e-303 951.0
WLSH2_k127_5583332_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 518.0
WLSH2_k127_5583332_11 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 503.0
WLSH2_k127_5583332_12 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 460.0
WLSH2_k127_5583332_13 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 463.0
WLSH2_k127_5583332_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 411.0
WLSH2_k127_5583332_15 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 375.0
WLSH2_k127_5583332_16 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 379.0
WLSH2_k127_5583332_17 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 357.0
WLSH2_k127_5583332_18 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 345.0
WLSH2_k127_5583332_19 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 348.0
WLSH2_k127_5583332_2 Aromatic amino acid lyase K01745 - 4.3.1.3 2.495e-245 770.0
WLSH2_k127_5583332_20 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 329.0
WLSH2_k127_5583332_21 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 299.0
WLSH2_k127_5583332_22 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 296.0
WLSH2_k127_5583332_23 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 285.0
WLSH2_k127_5583332_24 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001269 278.0
WLSH2_k127_5583332_25 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003105 288.0
WLSH2_k127_5583332_26 dGTPase activity K06885 - - 0.00000000000000000000000000000000000000000000000000000000000001481 229.0
WLSH2_k127_5583332_27 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000005321 200.0
WLSH2_k127_5583332_28 AAA domain - - - 0.0000000000000000000000000000000000000000000000004351 181.0
WLSH2_k127_5583332_29 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000001822 175.0
WLSH2_k127_5583332_3 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 2.059e-224 702.0
WLSH2_k127_5583332_30 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000001642 169.0
WLSH2_k127_5583332_31 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000005914 166.0
WLSH2_k127_5583332_32 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000003759 164.0
WLSH2_k127_5583332_33 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000002383 167.0
WLSH2_k127_5583332_34 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000436 167.0
WLSH2_k127_5583332_35 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000002523 160.0
WLSH2_k127_5583332_36 Protein of unknown function (DUF3261) - - - 0.0000000000000000000000000000000000000009679 155.0
WLSH2_k127_5583332_37 - - - - 0.00000000000000000000000000000000000002482 158.0
WLSH2_k127_5583332_38 NUDIX domain K12152 - - 0.0000000000000000000000000000000000009045 144.0
WLSH2_k127_5583332_39 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000001209 146.0
WLSH2_k127_5583332_4 Glycosyl transferase family 2 - - - 1.002e-215 684.0
WLSH2_k127_5583332_40 - - - - 0.000000000000000000000000000000000005763 150.0
WLSH2_k127_5583332_41 Dehydratase - - - 0.000000000000000000000000000000000009531 142.0
WLSH2_k127_5583332_42 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000002277 135.0
WLSH2_k127_5583332_43 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000006896 131.0
WLSH2_k127_5583332_44 membrane - - - 0.00000000000000000000000000000003381 133.0
WLSH2_k127_5583332_45 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000002777 124.0
WLSH2_k127_5583332_46 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000007592 128.0
WLSH2_k127_5583332_47 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000001024 117.0
WLSH2_k127_5583332_48 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000001385 130.0
WLSH2_k127_5583332_49 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000003126 108.0
WLSH2_k127_5583332_5 Heparinase II III family protein - - - 3.616e-208 665.0
WLSH2_k127_5583332_50 FOG TPR repeat - - - 0.0000000000000000000004285 109.0
WLSH2_k127_5583332_51 Thioredoxin - - - 0.0000000000000000001864 94.0
WLSH2_k127_5583332_52 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - 0.0000000000000001958 93.0
WLSH2_k127_5583332_53 Acetyltransferase (GNAT) domain - - - 0.0000000000000004465 81.0
WLSH2_k127_5583332_54 - - - - 0.0000000000000005161 83.0
WLSH2_k127_5583332_55 Domain of unknown function (DUF4266) - - - 0.0000000000002413 72.0
WLSH2_k127_5583332_56 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000001636 70.0
WLSH2_k127_5583332_57 - - - - 0.00001579 49.0
WLSH2_k127_5583332_58 PhoQ Sensor - - - 0.00001638 57.0
WLSH2_k127_5583332_59 A nuclease of the HNH/ENDO VII superfamily with conserved LHH - - - 0.00003421 55.0
WLSH2_k127_5583332_6 exporter - - - 5.154e-198 643.0
WLSH2_k127_5583332_7 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 604.0
WLSH2_k127_5583332_8 Thioredoxin-like K08344 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 585.0
WLSH2_k127_5583332_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 544.0
WLSH2_k127_5994067_0 Large extracellular alpha-helical protein K06894 - - 0.0 1917.0
WLSH2_k127_5994067_1 SNF2 family N-terminal domain - - - 0.0 1139.0
WLSH2_k127_5994067_10 COG0515 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 582.0
WLSH2_k127_5994067_11 K+ potassium transporter K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 541.0
WLSH2_k127_5994067_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 516.0
WLSH2_k127_5994067_13 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 518.0
WLSH2_k127_5994067_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 497.0
WLSH2_k127_5994067_15 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 488.0
WLSH2_k127_5994067_16 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 473.0
WLSH2_k127_5994067_17 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 460.0
WLSH2_k127_5994067_18 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 438.0
WLSH2_k127_5994067_19 COG1472 Beta-glucosidase-related glycosidases K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 438.0
WLSH2_k127_5994067_2 histidine kinase response regulator K13587 - 2.7.13.3 0.0 1125.0
WLSH2_k127_5994067_20 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 427.0
WLSH2_k127_5994067_21 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 418.0
WLSH2_k127_5994067_22 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 412.0
WLSH2_k127_5994067_23 Membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 396.0
WLSH2_k127_5994067_24 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 396.0
WLSH2_k127_5994067_25 COG1137 ABC-type (unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 383.0
WLSH2_k127_5994067_26 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 381.0
WLSH2_k127_5994067_27 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 369.0
WLSH2_k127_5994067_28 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 372.0
WLSH2_k127_5994067_29 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 344.0
WLSH2_k127_5994067_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.857e-308 953.0
WLSH2_k127_5994067_30 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 342.0
WLSH2_k127_5994067_31 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 345.0
WLSH2_k127_5994067_32 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 335.0
WLSH2_k127_5994067_33 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
WLSH2_k127_5994067_34 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
WLSH2_k127_5994067_35 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009683 258.0
WLSH2_k127_5994067_36 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
WLSH2_k127_5994067_37 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
WLSH2_k127_5994067_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002331 231.0
WLSH2_k127_5994067_39 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000002599 230.0
WLSH2_k127_5994067_4 Sodium:sulfate symporter transmembrane region K03319 - - 6.445e-226 707.0
WLSH2_k127_5994067_40 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000003733 229.0
WLSH2_k127_5994067_41 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
WLSH2_k127_5994067_42 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000001296 221.0
WLSH2_k127_5994067_43 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000002628 228.0
WLSH2_k127_5994067_44 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000007646 222.0
WLSH2_k127_5994067_45 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000006793 206.0
WLSH2_k127_5994067_46 Patatin-like phospholipase K06900 - - 0.00000000000000000000000000000000000000000000000000000001836 215.0
WLSH2_k127_5994067_47 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000797 197.0
WLSH2_k127_5994067_48 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000004504 195.0
WLSH2_k127_5994067_49 COG0558 Phosphatidylglycerophosphate synthase - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
WLSH2_k127_5994067_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.582e-224 709.0
WLSH2_k127_5994067_50 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000002286 187.0
WLSH2_k127_5994067_51 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000003123 187.0
WLSH2_k127_5994067_52 - - - - 0.0000000000000000000000000000000000000000000000005217 185.0
WLSH2_k127_5994067_53 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000001211 178.0
WLSH2_k127_5994067_54 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000000000000000000000000000000000000000002729 184.0
WLSH2_k127_5994067_55 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000001226 171.0
WLSH2_k127_5994067_56 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000006293 162.0
WLSH2_k127_5994067_57 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000001092 164.0
WLSH2_k127_5994067_58 - - - - 0.0000000000000000000000000000000000000000001416 177.0
WLSH2_k127_5994067_59 - - - - 0.0000000000000000000000000000000000000001517 159.0
WLSH2_k127_5994067_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.794e-212 665.0
WLSH2_k127_5994067_60 - - - - 0.0000000000000000000000000000000000000002499 158.0
WLSH2_k127_5994067_61 Gene 25-like lysozyme K11897 - - 0.000000000000000000000000000000000000007351 151.0
WLSH2_k127_5994067_62 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0000000000000000000000000000000001215 141.0
WLSH2_k127_5994067_63 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000001398 140.0
WLSH2_k127_5994067_64 Smr domain - - - 0.0000000000000000000000000006322 119.0
WLSH2_k127_5994067_65 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000001212 104.0
WLSH2_k127_5994067_66 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000001858 91.0
WLSH2_k127_5994067_67 - - - - 0.00000000000002886 77.0
WLSH2_k127_5994067_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.687e-209 657.0
WLSH2_k127_5994067_70 - - - - 0.0006651 43.0
WLSH2_k127_5994067_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.624e-203 643.0
WLSH2_k127_5994067_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 603.0
WLSH2_k127_6036451_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K02021,K11085 - - 3.85e-246 773.0
WLSH2_k127_6036451_1 CHASE4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 595.0
WLSH2_k127_6036451_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000003867 111.0
WLSH2_k127_6036451_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 507.0
WLSH2_k127_6036451_3 protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 286.0
WLSH2_k127_6036451_4 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003644 265.0
WLSH2_k127_6036451_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000025 209.0
WLSH2_k127_6036451_6 STAS domain K20978 - - 0.000000000000000000000000000000000000000000000002966 173.0
WLSH2_k127_6036451_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000007191 168.0
WLSH2_k127_6036451_8 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.00000000000000000000000000000000000000002163 155.0
WLSH2_k127_6036451_9 - - - - 0.00000000000000000000000000000004795 134.0
WLSH2_k127_6040546_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 485.0
WLSH2_k127_6040546_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000001097 100.0
WLSH2_k127_6108848_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
WLSH2_k127_6108848_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 362.0
WLSH2_k127_6108848_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003389 226.0
WLSH2_k127_6108848_3 Phage gp6-like head-tail connector protein - - - 0.0000000000000000000000000008191 119.0
WLSH2_k127_6108848_4 - - - - 0.0000000000000000000000000009478 117.0
WLSH2_k127_6108848_5 - - - - 0.00003431 51.0
WLSH2_k127_6160355_0 Ankyrin repeat domain protein - - - 0.00000000000000000000000000000000004416 156.0
WLSH2_k127_6235955_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1965.0
WLSH2_k127_6235955_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1080.0
WLSH2_k127_6235955_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000175 179.0
WLSH2_k127_6235955_11 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000121 153.0
WLSH2_k127_6235955_12 Uncharacterized protein conserved in bacteria (DUF2263) - - - 0.0000000000000000000000001329 118.0
WLSH2_k127_6235955_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000001212 106.0
WLSH2_k127_6235955_14 transposition - - - 0.0000000000000000000002971 108.0
WLSH2_k127_6235955_15 Protein of unknown function (DUF1467) - - - 0.000000000000000006258 87.0
WLSH2_k127_6235955_16 tail specific protease - - - 0.000003655 61.0
WLSH2_k127_6235955_17 transposition - - - 0.00003317 47.0
WLSH2_k127_6235955_2 PFAM type III restriction protein res subunit K01156 - 3.1.21.5 0.0 1049.0
WLSH2_k127_6235955_3 PFAM DNA methylase N-4 N-6 domain protein K07316 - 2.1.1.72 1.42e-237 754.0
WLSH2_k127_6235955_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 501.0
WLSH2_k127_6235955_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 380.0
WLSH2_k127_6235955_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004869 255.0
WLSH2_k127_6235955_8 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000001861 212.0
WLSH2_k127_6235955_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000001592 182.0
WLSH2_k127_6283679_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1133.0
WLSH2_k127_6283679_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA K00341 - 1.6.5.3 1.239e-289 901.0
WLSH2_k127_6283679_10 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 316.0
WLSH2_k127_6283679_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 300.0
WLSH2_k127_6283679_12 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
WLSH2_k127_6283679_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000006287 213.0
WLSH2_k127_6283679_14 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000001205 183.0
WLSH2_k127_6283679_15 protein secretion by the type IV secretion system - - - 0.00000000000000000000000000000000000000000004979 186.0
WLSH2_k127_6283679_16 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000001198 134.0
WLSH2_k127_6283679_17 Septum formation initiator - - - 0.00000000000000000000000000000003709 128.0
WLSH2_k127_6283679_18 2TM domain - - - 0.00000000000000000000000000002788 121.0
WLSH2_k127_6283679_19 ERAD pathway - - - 0.000000000000000000000000001101 120.0
WLSH2_k127_6283679_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) K00342 - 1.6.5.3 4.05e-248 773.0
WLSH2_k127_6283679_20 Ion channel - - - 0.0000000000000000000000002523 114.0
WLSH2_k127_6283679_3 Subtilase family - - - 1.979e-204 649.0
WLSH2_k127_6283679_4 Propionyl-CoA carboxylase alpha K01965 - 6.4.1.3 2.366e-203 656.0
WLSH2_k127_6283679_5 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 613.0
WLSH2_k127_6283679_6 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 542.0
WLSH2_k127_6283679_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 476.0
WLSH2_k127_6283679_8 Enoyl-CoA hydratase/isomerase K05605 - 3.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 406.0
WLSH2_k127_6283679_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 377.0
WLSH2_k127_6294733_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 299.0
WLSH2_k127_6385984_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1099.0
WLSH2_k127_6385984_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 550.0
WLSH2_k127_6385984_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 496.0
WLSH2_k127_6385984_3 Mortierella verticillata NRRL 6337 - - - 0.000000000000000000000000000000000000000000001438 184.0
WLSH2_k127_6385984_4 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000007308 139.0
WLSH2_k127_6385984_6 Leucine Rich repeat K17576 GO:0008150,GO:0009892,GO:0010563,GO:0010921,GO:0010923,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0035303,GO:0035305,GO:0043086,GO:0044092,GO:0045936,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051336,GO:0051346,GO:0065007,GO:0065009 - 0.00000000000000717 87.0
WLSH2_k127_6434029_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1292.0
WLSH2_k127_6434029_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000001299 156.0
WLSH2_k127_6434029_2 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000001169 148.0
WLSH2_k127_6559064_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1384.0
WLSH2_k127_6559064_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1264.0
WLSH2_k127_6559064_10 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 472.0
WLSH2_k127_6559064_11 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 445.0
WLSH2_k127_6559064_12 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 433.0
WLSH2_k127_6559064_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 404.0
WLSH2_k127_6559064_14 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 409.0
WLSH2_k127_6559064_15 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 383.0
WLSH2_k127_6559064_16 Pfam:HipA_N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 375.0
WLSH2_k127_6559064_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 378.0
WLSH2_k127_6559064_18 P-loop ATPase protein family K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 355.0
WLSH2_k127_6559064_19 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 359.0
WLSH2_k127_6559064_2 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0 1224.0
WLSH2_k127_6559064_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 339.0
WLSH2_k127_6559064_21 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 327.0
WLSH2_k127_6559064_22 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 326.0
WLSH2_k127_6559064_23 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 319.0
WLSH2_k127_6559064_24 Glycosyltransferase sugar-binding region containing DXD motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 321.0
WLSH2_k127_6559064_25 LicD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 317.0
WLSH2_k127_6559064_26 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 301.0
WLSH2_k127_6559064_27 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000001669 211.0
WLSH2_k127_6559064_28 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000000000000000001202 201.0
WLSH2_k127_6559064_29 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.000000000000000000000000000000000000000000000000000001424 197.0
WLSH2_k127_6559064_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1160.0
WLSH2_k127_6559064_30 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000001717 194.0
WLSH2_k127_6559064_31 Protein of unknown function (DUF2750) - - - 0.00000000000000000000000000000000000000000000001218 175.0
WLSH2_k127_6559064_32 - K03571 - - 0.0000000000000000000000000000000000000000000009814 170.0
WLSH2_k127_6559064_33 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000002167 150.0
WLSH2_k127_6559064_34 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000000005575 143.0
WLSH2_k127_6559064_36 kinase activity K07154 - 2.7.11.1 0.00000000000000000000000000006955 119.0
WLSH2_k127_6559064_37 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000001228 114.0
WLSH2_k127_6559064_38 beta-lactamase activity K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.0000000000000000000004233 113.0
WLSH2_k127_6559064_39 Pfam:DUF461 K09796 - - 0.0000000000000000003036 94.0
WLSH2_k127_6559064_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1069.0
WLSH2_k127_6559064_40 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000006062 83.0
WLSH2_k127_6559064_41 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000008308 82.0
WLSH2_k127_6559064_42 COG0842 ABC-type multidrug transport system, permease component K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000000000011 82.0
WLSH2_k127_6559064_46 OmpA-like transmembrane domain K16079 - - 0.000003793 57.0
WLSH2_k127_6559064_47 Major facilitator Superfamily - - - 0.000006361 48.0
WLSH2_k127_6559064_48 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.0001513 55.0
WLSH2_k127_6559064_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.082e-289 899.0
WLSH2_k127_6559064_6 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 8.389e-285 885.0
WLSH2_k127_6559064_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18989 - - 9.41e-221 721.0
WLSH2_k127_6559064_8 ABC transporter K01990 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 9.787e-209 663.0
WLSH2_k127_6559064_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 493.0
WLSH2_k127_6759875_0 isocitrate K00031 - 1.1.1.42 5.47e-251 780.0
WLSH2_k127_6759875_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 567.0
WLSH2_k127_6759875_10 Subtilase family - - - 0.000000000008888 78.0
WLSH2_k127_6759875_11 Subtilase family K13276,K17734 - - 0.00000006423 65.0
WLSH2_k127_6759875_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 458.0
WLSH2_k127_6759875_3 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 423.0
WLSH2_k127_6759875_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000395 285.0
WLSH2_k127_6759875_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000003799 220.0
WLSH2_k127_6759875_6 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000002492 214.0
WLSH2_k127_6759875_7 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000001032 212.0
WLSH2_k127_6759875_8 PFAM MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000001526 191.0
WLSH2_k127_6759875_9 PFAM regulatory protein TetR K09017 - - 0.0000000000000000000000000000000000000000000009033 172.0
WLSH2_k127_6783626_0 Protein of unknown function (DUF1670) - - - 0.000000000000000005925 94.0
WLSH2_k127_6783626_1 cellulose binding - - - 0.000000000001133 69.0
WLSH2_k127_6794406_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1400.0
WLSH2_k127_6794406_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 1.699e-274 875.0
WLSH2_k127_6794406_10 Domain of unknown function (DUF4347) - - - 0.000000006257 67.0
WLSH2_k127_6794406_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 478.0
WLSH2_k127_6794406_3 TrkA-N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 313.0
WLSH2_k127_6794406_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 245.0
WLSH2_k127_6794406_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000009058 230.0
WLSH2_k127_6794406_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000144 204.0
WLSH2_k127_6794406_8 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000002101 93.0
WLSH2_k127_7013934_0 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000001055 199.0
WLSH2_k127_7013934_1 - - - - 0.0000000000000000000000000000000000000001309 155.0
WLSH2_k127_7013934_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.000000000000000000000000000002772 120.0
WLSH2_k127_7021370_0 Malic enzyme K00029 - 1.1.1.40 0.0 1124.0
WLSH2_k127_7021370_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 467.0
WLSH2_k127_7021370_10 Bacterial export proteins, family 1 K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 261.0
WLSH2_k127_7021370_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000074 231.0
WLSH2_k127_7021370_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001574 198.0
WLSH2_k127_7021370_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000003427 173.0
WLSH2_k127_7021370_14 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000002246 167.0
WLSH2_k127_7021370_15 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000004828 143.0
WLSH2_k127_7021370_16 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000124 136.0
WLSH2_k127_7021370_17 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000000000000000002042 137.0
WLSH2_k127_7021370_18 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000000000143 120.0
WLSH2_k127_7021370_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000003653 129.0
WLSH2_k127_7021370_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 464.0
WLSH2_k127_7021370_20 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000001252 115.0
WLSH2_k127_7021370_21 - - - - 0.0000000000000000004193 99.0
WLSH2_k127_7021370_22 - - - - 0.00000000001018 74.0
WLSH2_k127_7021370_23 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000002222 69.0
WLSH2_k127_7021370_24 - - - - 0.0000000347 58.0
WLSH2_k127_7021370_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 452.0
WLSH2_k127_7021370_4 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 434.0
WLSH2_k127_7021370_5 ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 351.0
WLSH2_k127_7021370_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 292.0
WLSH2_k127_7021370_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 288.0
WLSH2_k127_7021370_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007712 284.0
WLSH2_k127_7021370_9 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001992 267.0
WLSH2_k127_7054256_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1350.0
WLSH2_k127_7054256_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 591.0
WLSH2_k127_7054256_10 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000539 59.0
WLSH2_k127_7054256_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 519.0
WLSH2_k127_7054256_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 520.0
WLSH2_k127_7054256_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 514.0
WLSH2_k127_7054256_5 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
WLSH2_k127_7054256_6 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 320.0
WLSH2_k127_7054256_7 hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
WLSH2_k127_7054256_8 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001482 274.0
WLSH2_k127_7332077_0 Phage portal protein, HK97 family - - - 1.581e-215 674.0
WLSH2_k127_7332077_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000001504 183.0
WLSH2_k127_7365017_0 Bacterial NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1092.0
WLSH2_k127_7365017_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05366 - 2.4.1.129,3.4.16.4 1.454e-294 921.0
WLSH2_k127_7365017_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 578.0
WLSH2_k127_7365017_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 541.0
WLSH2_k127_7365017_12 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 458.0
WLSH2_k127_7365017_13 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 460.0
WLSH2_k127_7365017_14 Rhodanese Homology Domain K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 449.0
WLSH2_k127_7365017_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 422.0
WLSH2_k127_7365017_16 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 399.0
WLSH2_k127_7365017_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 332.0
WLSH2_k127_7365017_18 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 311.0
WLSH2_k127_7365017_19 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 284.0
WLSH2_k127_7365017_2 Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity) K03466 - - 2.994e-281 889.0
WLSH2_k127_7365017_20 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
WLSH2_k127_7365017_21 COG2853 Surface lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008558 254.0
WLSH2_k127_7365017_22 regulation of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000000000000000000000000008135 221.0
WLSH2_k127_7365017_23 OmpA-like transmembrane domain K16079 - - 0.000000000000000000000000000000000000000000000000001835 189.0
WLSH2_k127_7365017_24 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000005932 169.0
WLSH2_k127_7365017_25 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000000001391 169.0
WLSH2_k127_7365017_26 RNA recognition motif - - - 0.00000000000000000000000000000000001959 137.0
WLSH2_k127_7365017_27 Succinate dehydrogenase, cytochrome b556 subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001042 136.0
WLSH2_k127_7365017_28 OmpA-like transmembrane domain K16079 - - 0.00000000000000000000000000000000444 136.0
WLSH2_k127_7365017_29 Succinate dehydrogenase hydrophobic K00242 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000006502 126.0
WLSH2_k127_7365017_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.546e-277 861.0
WLSH2_k127_7365017_30 - K02387 - - 0.0000000000000000000000003836 108.0
WLSH2_k127_7365017_31 Frataxin-like domain K06202 - - 0.000000000000000000000003252 105.0
WLSH2_k127_7365017_32 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000016 99.0
WLSH2_k127_7365017_33 Global regulator protein family K03563 - - 0.000000000000000148 83.0
WLSH2_k127_7365017_34 Sugar (and other) transporter K07552 - - 0.0000000007282 71.0
WLSH2_k127_7365017_35 - - - - 0.000000002294 58.0
WLSH2_k127_7365017_4 Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity) K06147 - - 6.78e-259 810.0
WLSH2_k127_7365017_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.998e-251 788.0
WLSH2_k127_7365017_6 E1-E2 ATPase - - - 2.566e-222 706.0
WLSH2_k127_7365017_7 Major facilitator K03762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
WLSH2_k127_7365017_8 Rod shape-determining protein (MreB) K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 586.0
WLSH2_k127_7365017_9 Sugar phosphate permease K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 590.0
WLSH2_k127_737038_0 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
WLSH2_k127_737038_1 GrpB protein - - - 0.00000000000000000000000000000000000000000000000001407 186.0
WLSH2_k127_737038_2 - - - - 0.00000000000000000000000008645 113.0
WLSH2_k127_7445762_0 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) K16898 - 3.6.4.12 7.4e-323 1023.0
WLSH2_k127_7445762_1 transposase activity K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 465.0
WLSH2_k127_7445762_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004397 212.0
WLSH2_k127_7445762_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03805,K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000007619 214.0
WLSH2_k127_7445762_4 Subtilase family - - - 0.0002259 52.0
WLSH2_k127_7464295_0 secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 419.0
WLSH2_k127_7464295_1 Bacterial type II and III secretion system protein K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 406.0
WLSH2_k127_7464295_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
WLSH2_k127_7464295_3 Pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 333.0
WLSH2_k127_7464295_4 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000001762 203.0
WLSH2_k127_7464295_5 Pilus assembly protein K12510 - - 0.0000000000000000000000000000000000000000000000000000002649 206.0
WLSH2_k127_7464295_6 SmpA / OmlA family - - - 0.0000000000000000000000000000000000000000000000002195 183.0
WLSH2_k127_7464295_7 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000000000000000000001033 169.0
WLSH2_k127_7464295_9 Pilus biogenesis CpaD protein (pilus_cpaD) K02281 - - 0.000000000000000001577 94.0
WLSH2_k127_7506261_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity) K02337 - 2.7.7.7 0.0 1362.0
WLSH2_k127_7506261_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 7.012e-312 968.0
WLSH2_k127_7506261_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000000000002893 145.0
WLSH2_k127_7506261_11 bacterial-type flagellum organization K02411 - - 0.00000000000000000000000000000002621 134.0
WLSH2_k127_7506261_12 - - - - 0.00000000000000000000000007008 110.0
WLSH2_k127_7506261_14 - - - - 0.00000001472 59.0
WLSH2_k127_7506261_15 Belongs to the peptidase S8 family - - - 0.000003954 59.0
WLSH2_k127_7506261_2 The M ring may be actively involved in energy transduction K02409 - - 6.571e-215 681.0
WLSH2_k127_7506261_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 600.0
WLSH2_k127_7506261_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 571.0
WLSH2_k127_7506261_5 FliG middle domain K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 372.0
WLSH2_k127_7506261_6 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 353.0
WLSH2_k127_7506261_7 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 313.0
WLSH2_k127_7506261_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
WLSH2_k127_7506261_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000001298 181.0
WLSH2_k127_7628928_0 Haloacid dehalogenase K17686 - 3.6.3.54 1.245e-233 743.0
WLSH2_k127_7628928_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 617.0
WLSH2_k127_7628928_2 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 563.0
WLSH2_k127_7628928_3 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000002898 242.0
WLSH2_k127_7628928_4 Belongs to the peptidase S24 family K03503 - - 0.0000000000000000000000000000000000000000000000000000002315 199.0
WLSH2_k127_7628928_5 universal stress protein - - - 0.00000000000000000000000000003928 121.0
WLSH2_k127_7628928_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000005956 115.0
WLSH2_k127_7628928_7 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000004809 106.0
WLSH2_k127_7628928_8 Leucine-rich repeat (LRR) protein - - - 0.0005777 51.0
WLSH2_k127_7629747_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 601.0
WLSH2_k127_7629747_1 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 490.0
WLSH2_k127_7629747_10 The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions K03210 - - 0.0000000000000000000000000000003547 125.0
WLSH2_k127_7629747_11 DUF167 K09131 - - 0.000000000000000000000001449 106.0
WLSH2_k127_7629747_12 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00002196 47.0
WLSH2_k127_7629747_2 Protein export membrane protein K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 479.0
WLSH2_k127_7629747_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 445.0
WLSH2_k127_7629747_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 421.0
WLSH2_k127_7629747_5 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 304.0
WLSH2_k127_7629747_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 286.0
WLSH2_k127_7629747_7 Regulator of competence-specific genes - - - 0.0000000000000000000000000000000000000000000006033 168.0
WLSH2_k127_7629747_8 Lysin motif - - - 0.000000000000000000000000000000000000000000001095 173.0
WLSH2_k127_7629747_9 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000001049 141.0
WLSH2_k127_7630023_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 393.0
WLSH2_k127_7630023_1 Dicarboxylate transport - - - 0.000000000000000002912 100.0
WLSH2_k127_7630023_2 YnbE-like lipoprotein - - - 0.0000000000003581 74.0
WLSH2_k127_7630023_3 conserved protein UCP025560 K09978 - - 0.00004286 49.0
WLSH2_k127_7643771_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 602.0
WLSH2_k127_7643771_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 395.0
WLSH2_k127_7643771_2 - - - - 0.00000052 57.0
WLSH2_k127_7650838_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000001601 192.0
WLSH2_k127_7900556_0 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000002691 229.0
WLSH2_k127_7900556_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000851 233.0
WLSH2_k127_7900556_2 Mortierella verticillata NRRL 6337 - - - 0.0000000000000000000000000000000001037 155.0
WLSH2_k127_7900556_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000006455 79.0
WLSH2_k127_8031947_0 COG0642 Signal transduction histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 392.0
WLSH2_k127_8087545_0 Cysteine-rich domain - - - 2.822e-201 634.0
WLSH2_k127_8087545_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 477.0
WLSH2_k127_8087545_10 regulation of response to stimulus - - - 0.0000000000000004401 92.0
WLSH2_k127_8087545_2 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 415.0
WLSH2_k127_8087545_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 386.0
WLSH2_k127_8087545_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 346.0
WLSH2_k127_8087545_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003094 254.0
WLSH2_k127_8087545_6 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003636 226.0
WLSH2_k127_8087545_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000002419 212.0
WLSH2_k127_8087545_8 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000004977 210.0
WLSH2_k127_8087545_9 Transcriptional regulator - - - 0.0000000000000002615 82.0
WLSH2_k127_8113190_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.892e-205 646.0
WLSH2_k127_8113190_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.063e-195 616.0
WLSH2_k127_8113190_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000003256 202.0
WLSH2_k127_8113190_11 AAA domain - - - 0.0000000000000000000000000000000000000001254 153.0
WLSH2_k127_8113190_12 peptidoglycan biosynthetic process - - - 0.000000000000000000000000000000000000002087 152.0
WLSH2_k127_8113190_13 OmpA-like transmembrane domain K16079 - - 0.000000000000000000000000000000001004 139.0
WLSH2_k127_8113190_15 Transposase - - - 0.0000008455 51.0
WLSH2_k127_8113190_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 585.0
WLSH2_k127_8113190_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 512.0
WLSH2_k127_8113190_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 385.0
WLSH2_k127_8113190_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 380.0
WLSH2_k127_8113190_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 367.0
WLSH2_k127_8113190_7 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 357.0
WLSH2_k127_8113190_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 357.0
WLSH2_k127_8113190_9 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002965 243.0
WLSH2_k127_8234420_0 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 482.0
WLSH2_k127_8234420_1 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 471.0
WLSH2_k127_8234420_10 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000005095 203.0
WLSH2_k127_8234420_11 Flagellar protein FliS K02422 - - 0.0000000000000000000000000005793 117.0
WLSH2_k127_8234420_12 regulation of response to stimulus - - - 0.0000000000000000000003642 109.0
WLSH2_k127_8234420_13 - - - - 0.0000000000000000001234 100.0
WLSH2_k127_8234420_14 Belongs to the peptidase C1 family - - - 0.00000000000000003307 94.0
WLSH2_k127_8234420_15 Acid phosphatase homologues - - - 0.00000000000002739 81.0
WLSH2_k127_8234420_16 Trypsin-like serine protease - - - 0.00000000006122 74.0
WLSH2_k127_8234420_17 SEC-C motif - - - 0.00004439 54.0
WLSH2_k127_8234420_18 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 - 2.1.1.197,6.3.3.3 0.0002031 44.0
WLSH2_k127_8234420_2 Bacterial flagellin N-terminal helical region K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 457.0
WLSH2_k127_8234420_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 397.0
WLSH2_k127_8234420_4 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 376.0
WLSH2_k127_8234420_5 dehydrogenases with different specificities (related to short-chain alcohol) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 360.0
WLSH2_k127_8234420_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 359.0
WLSH2_k127_8234420_7 Flagellar hook-associated protein 2 N-terminus K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 304.0
WLSH2_k127_8234420_8 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 257.0
WLSH2_k127_8234420_9 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000001119 219.0
WLSH2_k127_8403132_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1386.0
WLSH2_k127_8403132_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 1.188e-209 655.0
WLSH2_k127_8403132_10 ATPase domain predominantly from Archaea K06921 - - 0.000601 43.0
WLSH2_k127_8403132_2 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 346.0
WLSH2_k127_8403132_3 Phasin protein - - - 0.000000000000000000000000000000000504 136.0
WLSH2_k127_8403132_4 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000006093 110.0
WLSH2_k127_8403132_5 Ankyrin repeat - - - 0.000000000000000000001138 112.0
WLSH2_k127_8403132_6 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000003363 101.0
WLSH2_k127_8403132_7 Helix-turn-helix XRE-family like proteins K18831 - - 0.00000000004185 66.0
WLSH2_k127_8403132_8 Leucine Rich repeat - - - 0.0000000005482 72.0
WLSH2_k127_8403132_9 - - - - 0.0001439 56.0
WLSH2_k127_8479513_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 4.561e-228 718.0
WLSH2_k127_8479513_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 9.768e-227 707.0
WLSH2_k127_8479513_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000004084 134.0
WLSH2_k127_8479513_11 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000004699 142.0
WLSH2_k127_8479513_12 - - - - 0.000000000000003116 85.0
WLSH2_k127_8479513_13 - - - - 0.000000000001189 70.0
WLSH2_k127_8479513_14 Suppressor of fused protein (SUFU) - - - 0.00000000000941 74.0
WLSH2_k127_8479513_15 DNA gyrase inhibitor YacG - - - 0.000000001476 61.0
WLSH2_k127_8479513_2 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 430.0
WLSH2_k127_8479513_3 Sigma-70, region 4 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 398.0
WLSH2_k127_8479513_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 413.0
WLSH2_k127_8479513_5 Cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 331.0
WLSH2_k127_8479513_6 Organic solvent ABC transporter ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
WLSH2_k127_8479513_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001024 264.0
WLSH2_k127_8479513_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000008268 237.0
WLSH2_k127_8479513_9 - - - - 0.00000000000000000000000000000000000000008925 158.0
WLSH2_k127_8536357_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 325.0
WLSH2_k127_8536357_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009067 292.0
WLSH2_k127_8536357_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002617 248.0
WLSH2_k127_8536357_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000001885 102.0
WLSH2_k127_8536357_4 structural constituent of ribosome K02919 - - 0.00000000000000003567 81.0
WLSH2_k127_8536357_5 AAA domain K07133 - - 0.000000003482 59.0
WLSH2_k127_8536357_7 COG4886 Leucine-rich repeat (LRR) protein K19613 - - 0.000002266 62.0
WLSH2_k127_8604984_0 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 432.0
WLSH2_k127_8604984_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 411.0
WLSH2_k127_8604984_11 - - - - 0.0000004957 57.0
WLSH2_k127_8604984_2 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 315.0
WLSH2_k127_8604984_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
WLSH2_k127_8604984_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000007794 241.0
WLSH2_k127_8604984_5 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.0000000000000000000000000000000000000000000000000000000001293 211.0
WLSH2_k127_8604984_6 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
WLSH2_k127_8604984_7 Flagellar basal body-associated protein FliL K02415 - - 0.00000000000000000000000000000000000000000000001512 176.0
WLSH2_k127_8604984_8 MgtE intracellular N domain - - - 0.000000000000000000000000000000000001238 152.0
WLSH2_k127_8604984_9 - - - - 0.00000000000000000000000000000000008808 141.0
WLSH2_k127_8665575_0 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 8.732e-318 985.0
WLSH2_k127_8665575_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.093e-236 735.0
WLSH2_k127_8665575_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002958 259.0
WLSH2_k127_8665575_11 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000009657 227.0
WLSH2_k127_8665575_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002911 201.0
WLSH2_k127_8665575_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000003701 157.0
WLSH2_k127_8665575_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.988e-213 666.0
WLSH2_k127_8665575_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 604.0
WLSH2_k127_8665575_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 544.0
WLSH2_k127_8665575_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
WLSH2_k127_8665575_6 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K03940 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 327.0
WLSH2_k127_8665575_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 292.0
WLSH2_k127_8665575_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 286.0
WLSH2_k127_8665575_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000234 276.0
WLSH2_k127_8695560_0 OPT oligopeptide transporter protein - - - 2.925e-304 947.0
WLSH2_k127_8695560_1 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
WLSH2_k127_8695560_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
WLSH2_k127_8695560_3 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000414 188.0
WLSH2_k127_8695560_4 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000000003034 151.0
WLSH2_k127_8695560_5 PAP2 superfamily - - - 0.00000000000000000000000000000000000002647 154.0
WLSH2_k127_8695560_6 Belongs to the peptidase S8 family - - - 0.0000000000000001404 92.0
WLSH2_k127_8714277_0 COG0477 Permeases of the major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 0.0 1509.0
WLSH2_k127_8714277_1 N-Acetylmuramoyl-L-alanine amidase K11066 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000005837 259.0
WLSH2_k127_8714277_10 Hsp20/alpha crystallin family K13993 - - 0.0001015 53.0
WLSH2_k127_8714277_2 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000482 223.0
WLSH2_k127_8714277_3 - - - - 0.000000000000000000000000000000000002061 144.0
WLSH2_k127_8714277_4 Inositol hexakisphosphate - - - 0.0000000000000000000000000000008809 134.0
WLSH2_k127_8714277_5 DDE_Tnp_1-associated - - - 0.000000000000000000000009416 108.0
WLSH2_k127_8714277_6 - - - - 0.000000000000000001705 88.0
WLSH2_k127_8714277_7 PFAM transposase IS4 family protein - - - 0.0000000007867 67.0
WLSH2_k127_8714277_8 Lipase (class 3) - - - 0.00000961 58.0
WLSH2_k127_8714277_9 Domain of unknown function (DUF4143) - - - 0.00005401 46.0
WLSH2_k127_8760973_0 Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism K03301 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264 - 7.294e-241 753.0
WLSH2_k127_8760973_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 1.994e-201 634.0
WLSH2_k127_8760973_10 Cold shock protein domain K03704 - - 0.000000000000000000000000002579 113.0
WLSH2_k127_8760973_11 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000007219 108.0
WLSH2_k127_8760973_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 301.0
WLSH2_k127_8760973_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 293.0
WLSH2_k127_8760973_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
WLSH2_k127_8760973_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
WLSH2_k127_8760973_6 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005522 245.0
WLSH2_k127_8760973_7 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000008232 228.0
WLSH2_k127_8760973_8 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000366 184.0
WLSH2_k127_8760973_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000001425 117.0
WLSH2_k127_8775111_0 Acyl-CoA dehydrogenase N terminal - - - 2.454e-295 915.0
WLSH2_k127_8775111_1 3-hydroxyacyl-CoA dehydrogenase K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 8.138e-266 827.0
WLSH2_k127_8775111_2 Mortierella verticillata NRRL 6337 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 386.0
WLSH2_k127_8775111_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 341.0
WLSH2_k127_8806943_0 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
WLSH2_k127_8806943_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 365.0
WLSH2_k127_8806943_2 Epimerase dehydratase K02377,K22252 - 1.1.1.135,1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000002785 245.0
WLSH2_k127_8806943_3 Bacterial sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
WLSH2_k127_8806943_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000002232 196.0
WLSH2_k127_8806943_5 deaminase - - - 0.0000000000000000000000000000000000000000000000006769 180.0
WLSH2_k127_8806943_6 enzyme of heme biosynthesis K02496,K05802,K08884,K18827 - 2.1.1.107,2.1.1.294,2.7.1.181,2.7.11.1 0.000000000000000002767 95.0
WLSH2_k127_8806943_7 OmpA family K02557 - - 0.000008162 56.0
WLSH2_k127_8831835_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 4.008e-284 880.0
WLSH2_k127_8831835_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.603e-227 720.0
WLSH2_k127_8831835_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.52e-208 664.0
WLSH2_k127_8831835_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 530.0
WLSH2_k127_8831835_4 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 300.0
WLSH2_k127_8831835_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
WLSH2_k127_8831835_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000007524 201.0
WLSH2_k127_89883_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.995e-252 785.0
WLSH2_k127_89883_1 Alpha/beta hydrolase family - - - 0.0003401 51.0
WLSH2_k127_9008436_0 Type VI secretion system, TssF K11896 - - 5.022e-259 814.0
WLSH2_k127_9008436_1 propionyl-CoA carboxylase beta K01966 - 2.1.3.15,6.4.1.3 3.24e-258 804.0
WLSH2_k127_9008436_2 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000000000000000001343 208.0
WLSH2_k127_9143389_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.933e-216 676.0
WLSH2_k127_9143389_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 4.148e-207 649.0
WLSH2_k127_9143389_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000007783 109.0
WLSH2_k127_9143389_11 GGDEF domain containing protein - - - 0.000002807 51.0
WLSH2_k127_9143389_13 - - - - 0.0000489 46.0
WLSH2_k127_9143389_14 - - - - 0.0000879 45.0
WLSH2_k127_9143389_2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 568.0
WLSH2_k127_9143389_3 Permease K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 408.0
WLSH2_k127_9143389_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 317.0
WLSH2_k127_9143389_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 302.0
WLSH2_k127_9143389_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
WLSH2_k127_9143389_7 ATPase involved in DNA replication initiation - - - 0.00000000000000000000000000000000000000000000001079 179.0
WLSH2_k127_9143389_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000004569 173.0
WLSH2_k127_9143389_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000001298 124.0
WLSH2_k127_9162936_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 473.0
WLSH2_k127_9162936_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
WLSH2_k127_9162936_2 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000002482 184.0
WLSH2_k127_9162936_3 Transposase DDE domain - - - 0.0000003622 52.0
WLSH2_k127_9162936_4 Transposase DDE domain - - - 0.000001046 54.0
WLSH2_k127_9181525_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 2.414e-194 614.0
WLSH2_k127_9181525_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 455.0
WLSH2_k127_9181525_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K13584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 427.0
WLSH2_k127_9181525_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 353.0
WLSH2_k127_9181525_4 Secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000004862 220.0
WLSH2_k127_9181525_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000001402 66.0
WLSH2_k127_9201504_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.947e-236 735.0
WLSH2_k127_9201504_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.654e-212 668.0
WLSH2_k127_9201504_10 TadE-like protein - - - 0.000000000000002824 83.0
WLSH2_k127_9201504_11 TadE-like protein - - - 0.000000009394 63.0
WLSH2_k127_9201504_12 PFAM Flp Fap pilin component K02651 - - 0.0000007509 53.0
WLSH2_k127_9201504_14 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.00001089 55.0
WLSH2_k127_9201504_15 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00001332 55.0
WLSH2_k127_9201504_2 DNA photolyase domain protein K01669 - 4.1.99.3 3.843e-211 666.0
WLSH2_k127_9201504_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.394e-208 662.0
WLSH2_k127_9201504_4 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 607.0
WLSH2_k127_9201504_5 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 520.0
WLSH2_k127_9201504_6 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 392.0
WLSH2_k127_9201504_7 FtsX-like permease family K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 392.0
WLSH2_k127_9201504_8 Flp pilus assembly protein TadG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 353.0
WLSH2_k127_9201504_9 Flp pilus assembly protein TadG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 327.0
WLSH2_k127_9244315_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.586e-290 905.0
WLSH2_k127_9244315_1 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 3.156e-220 704.0
WLSH2_k127_9244315_10 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 291.0
WLSH2_k127_9244315_11 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
WLSH2_k127_9244315_12 Patatin-like phospholipase K06900 - - 0.0000000000000000000000000000000000000000000000000000000000000000003303 254.0
WLSH2_k127_9244315_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000001657 230.0
WLSH2_k127_9244315_14 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000004388 230.0
WLSH2_k127_9244315_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
WLSH2_k127_9244315_16 PFAM Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000003886 203.0
WLSH2_k127_9244315_17 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000001268 183.0
WLSH2_k127_9244315_18 UPF0060 membrane protein K09771 - - 0.000000000000000000000000000000000000000002544 157.0
WLSH2_k127_9244315_2 Phage late control gene D protein (GPD) K11904 - - 4.063e-212 676.0
WLSH2_k127_9244315_20 Thioredoxin - - - 0.0000000000000000000000000000000000001736 150.0
WLSH2_k127_9244315_21 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000000000000000000000000000001199 138.0
WLSH2_k127_9244315_22 PFAM Patatin - - - 0.0000000000000000000003464 113.0
WLSH2_k127_9244315_23 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000004211 63.0
WLSH2_k127_9244315_24 Sel1-like repeats. K07126 - - 0.000007826 58.0
WLSH2_k127_9244315_25 cell differentiation - - - 0.00007231 54.0
WLSH2_k127_9244315_26 HlyD family secretion protein K03543 - - 0.0009364 51.0
WLSH2_k127_9244315_3 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 604.0
WLSH2_k127_9244315_4 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 484.0
WLSH2_k127_9244315_5 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 472.0
WLSH2_k127_9244315_6 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 464.0
WLSH2_k127_9244315_7 Virulence protein RhuM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 439.0
WLSH2_k127_9244315_8 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 387.0
WLSH2_k127_9244315_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 326.0
WLSH2_k127_9246090_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1572.0
WLSH2_k127_9246090_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1015.0
WLSH2_k127_9246090_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000007815 253.0
WLSH2_k127_9246090_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000001433 184.0
WLSH2_k127_9246090_12 YGGT family K02221 - - 0.00000000000000000000000000000001035 129.0
WLSH2_k127_9246090_14 aromatic hydrocarbon degradation K06076 - - 0.0000000000000000001373 102.0
WLSH2_k127_9246090_15 - - - - 0.0000000000000002417 87.0
WLSH2_k127_9246090_16 Leucine-rich transmembrane protein - GO:0000902,GO:0007275,GO:0007399,GO:0008150,GO:0009653,GO:0009987,GO:0016043,GO:0022008,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0071840,GO:0120036,GO:0120039 - 0.00006632 53.0
WLSH2_k127_9246090_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 506.0
WLSH2_k127_9246090_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 464.0
WLSH2_k127_9246090_4 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 447.0
WLSH2_k127_9246090_5 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 356.0
WLSH2_k127_9246090_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 307.0
WLSH2_k127_9246090_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 310.0
WLSH2_k127_9246090_8 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003523 283.0
WLSH2_k127_9246090_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
WLSH2_k127_9363056_0 Oligopeptidase F K08602 - - 8.133e-255 801.0
WLSH2_k127_9363056_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 613.0
WLSH2_k127_9363056_2 fungal-type cell wall polysaccharide biosynthetic process K07126 GO:0000003,GO:0000131,GO:0000271,GO:0003006,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005628,GO:0005933,GO:0005935,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006030,GO:0006031,GO:0006037,GO:0006038,GO:0006040,GO:0006807,GO:0007049,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009272,GO:0009653,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0017144,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030234,GO:0030427,GO:0030435,GO:0030437,GO:0032502,GO:0032505,GO:0033692,GO:0034221,GO:0034293,GO:0034637,GO:0034645,GO:0042546,GO:0042763,GO:0042764,GO:0043085,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044464,GO:0044703,GO:0046349,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050790,GO:0051278,GO:0051321,GO:0051704,GO:0065007,GO:0065009,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071852,GO:0071966,GO:0098772,GO:1901071,GO:1901073,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903046 - 0.0000000000000000000000000000000000000000000000002451 199.0
WLSH2_k127_9363056_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000003249 114.0
WLSH2_k127_9363056_5 mRNA cleavage K07126,K19158 - - 0.00000000000000000003568 104.0
WLSH2_k127_9532524_0 RNB - - - 1.297e-270 857.0
WLSH2_k127_9532524_1 Tryptophan/tyrosine permease family K03834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002659 262.0
WLSH2_k127_9532524_2 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000001267 78.0
WLSH2_k127_9532524_3 Leucine rich repeat containing - - - 0.000000000178 71.0
WLSH2_k127_955197_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000003043 98.0
WLSH2_k127_9558743_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 6.583e-247 767.0
WLSH2_k127_9558743_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 580.0
WLSH2_k127_9558743_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 450.0
WLSH2_k127_9558743_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 313.0
WLSH2_k127_9558743_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000003022 217.0
WLSH2_k127_9558743_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000009995 174.0
WLSH2_k127_9630867_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1131.0
WLSH2_k127_9630867_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.013e-229 719.0
WLSH2_k127_9630867_10 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000008731 130.0
WLSH2_k127_9630867_11 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000000001654 106.0
WLSH2_k127_9630867_12 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000001267 112.0
WLSH2_k127_9630867_13 - - - - 0.00000000000000000000003387 106.0
WLSH2_k127_9630867_14 OmpA-like transmembrane domain K16079 - - 0.0000000000000002358 88.0
WLSH2_k127_9630867_2 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 539.0
WLSH2_k127_9630867_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
WLSH2_k127_9630867_4 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 439.0
WLSH2_k127_9630867_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 364.0
WLSH2_k127_9630867_6 DNA processing protein K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 348.0
WLSH2_k127_9630867_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 318.0
WLSH2_k127_9630867_8 protein secretion K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 305.0
WLSH2_k127_9630867_9 sugar phosphatases of the HAD superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002224 230.0
WLSH2_k127_9712920_0 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0 1682.0
WLSH2_k127_9712920_1 Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity) K03657 - 3.6.4.12 2.477e-284 889.0
WLSH2_k127_9712920_2 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 546.0
WLSH2_k127_9712920_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 376.0
WLSH2_k127_9712920_4 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000004695 200.0
WLSH2_k127_9712920_5 DnaJ C terminal domain K09510 - - 0.000001854 58.0
WLSH2_k127_9712920_6 - - - - 0.00001005 58.0
WLSH2_k127_9712920_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0001352 52.0
WLSH2_k127_9712920_8 - - - - 0.0007927 52.0
WLSH2_k127_971674_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 514.0
WLSH2_k127_971674_1 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 456.0
WLSH2_k127_971674_10 FliW protein K13626 - - 0.000000000000000000000003871 108.0
WLSH2_k127_971674_11 - - - - 0.000000000000000000003823 98.0
WLSH2_k127_971674_13 PFAM type II secretion system K12511 - - 0.000000000001718 77.0
WLSH2_k127_971674_2 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
WLSH2_k127_971674_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 293.0
WLSH2_k127_971674_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003073 251.0
WLSH2_k127_971674_5 ABC-type Mn2 Zn2 transport systems, permease components K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000007743 239.0
WLSH2_k127_971674_6 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000003419 222.0
WLSH2_k127_971674_7 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000000000088 206.0
WLSH2_k127_971674_8 COG3344 Retron-type reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000003673 195.0
WLSH2_k127_971674_9 Rod binding protein - - - 0.0000000000000000000000000000000005034 133.0
WLSH2_k127_9723668_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 595.0
WLSH2_k127_9723668_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 587.0
WLSH2_k127_9723668_10 Transposase - - - 0.0000000000000001335 81.0
WLSH2_k127_9723668_11 Transposase, Mutator family - - - 0.0000000009374 59.0
WLSH2_k127_9723668_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 509.0
WLSH2_k127_9723668_3 COG0477 Permeases of the major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 458.0
WLSH2_k127_9723668_4 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003256 271.0
WLSH2_k127_9723668_5 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008131 245.0
WLSH2_k127_9723668_6 cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000001304 239.0
WLSH2_k127_9723668_7 Cytochrome C K08738 - - 0.00000000000000000000000000000000000000000000000000000000000776 211.0
WLSH2_k127_9723668_9 Usg-like family - - - 0.00000000000000000000000000002181 121.0
WLSH2_k127_9775919_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.495e-225 704.0
WLSH2_k127_9775919_1 Oligopeptide/dipeptide transporter, C-terminal region K13896 - - 5.169e-224 705.0
WLSH2_k127_9775919_10 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 303.0
WLSH2_k127_9775919_11 Fungal trichothecene efflux pump (TRI12) K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001641 276.0
WLSH2_k127_9775919_12 Secretion protein K02022,K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002984 271.0
WLSH2_k127_9775919_13 N-Acetylmuramoyl-L-alanine amidase K11066 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001716 248.0
WLSH2_k127_9775919_14 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000002236 222.0
WLSH2_k127_9775919_15 protein conserved in bacteria K09985 - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
WLSH2_k127_9775919_16 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000004712 214.0
WLSH2_k127_9775919_17 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000474 203.0
WLSH2_k127_9775919_18 Alanine racemase, N-terminal domain K06997 - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
WLSH2_k127_9775919_19 2OG-Fe dioxygenase - - - 0.0000000000000000000000000000000000000000000002002 179.0
WLSH2_k127_9775919_2 PHB de-polymerase C-terminus K05973 - 3.1.1.75 2.124e-198 625.0
WLSH2_k127_9775919_20 Protein kinase C inhibitor 1 - - - 0.0000000000000000000000000000000000000000000002852 169.0
WLSH2_k127_9775919_21 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000403 171.0
WLSH2_k127_9775919_22 HIT domain - - - 0.00000000000000000000000000000000000000000004913 164.0
WLSH2_k127_9775919_23 AzlC protein - - - 0.000000000000000000000000000000000000000002684 163.0
WLSH2_k127_9775919_24 general secretion pathway protein - - - 0.000000000000000000000000000000000000000007235 166.0
WLSH2_k127_9775919_25 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000005129 132.0
WLSH2_k127_9775919_28 Protein of unknown function (DUF465) - - - 0.000000003744 63.0
WLSH2_k127_9775919_3 acyl-CoA dehydrogenase K00252 - 1.3.8.6 4.782e-198 623.0
WLSH2_k127_9775919_30 Protein of unknown function (DUF1653) - - - 0.00000008033 55.0
WLSH2_k127_9775919_31 - - - - 0.0000002775 53.0
WLSH2_k127_9775919_32 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000007917 52.0
WLSH2_k127_9775919_4 Binding-protein-dependent transport system inner membrane component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 576.0
WLSH2_k127_9775919_5 Binding-protein-dependent transport system inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 547.0
WLSH2_k127_9775919_6 ABC transporter transmembrane region K12541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 538.0
WLSH2_k127_9775919_7 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 494.0
WLSH2_k127_9775919_8 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 395.0
WLSH2_k127_9775919_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 297.0
WLSH2_k127_9878474_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000006193 222.0