Overview

ID MAG04230
Name WLSH2_bin.69
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-41
Genus Ga0077527
Species
Assembly information
Completeness (%) 67.01
Contamination (%) 1.5
GC content (%) 63.0
N50 (bp) 9,450
Genome size (bp) 1,615,342

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1732

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10016808_0 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 386.0
WLSH2_k127_10016808_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 362.0
WLSH2_k127_10016808_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003301 253.0
WLSH2_k127_10016808_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000003577 124.0
WLSH2_k127_10016808_4 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000002191 123.0
WLSH2_k127_10022102_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.888e-223 702.0
WLSH2_k127_10022102_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 324.0
WLSH2_k127_10022102_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003485 269.0
WLSH2_k127_10022102_3 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009346 246.0
WLSH2_k127_10022102_4 two-component sensor kinase K07649 - 2.7.13.3 0.00000000000000000001104 99.0
WLSH2_k127_1004255_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 500.0
WLSH2_k127_1004255_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 402.0
WLSH2_k127_1004255_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000001299 218.0
WLSH2_k127_1004255_3 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000000000000000000004834 205.0
WLSH2_k127_1004255_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000002644 177.0
WLSH2_k127_1004255_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000005756 117.0
WLSH2_k127_1019250_0 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 497.0
WLSH2_k127_1019250_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 484.0
WLSH2_k127_1019250_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 452.0
WLSH2_k127_1019250_3 Glycosyl transferase, family 2 K16555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 451.0
WLSH2_k127_1019250_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 348.0
WLSH2_k127_1019250_5 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 302.0
WLSH2_k127_1019250_6 Glycosyl transferase, family 2 K00721,K07011,K20444 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000003456 237.0
WLSH2_k127_1019250_7 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000008353 231.0
WLSH2_k127_1019250_8 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000001786 188.0
WLSH2_k127_1019250_9 - - - - 0.00000000000000000000000000000000000000000007288 176.0
WLSH2_k127_10416475_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 571.0
WLSH2_k127_10416475_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 512.0
WLSH2_k127_10416475_10 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
WLSH2_k127_10416475_11 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
WLSH2_k127_10416475_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005738 244.0
WLSH2_k127_10416475_13 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000007568 227.0
WLSH2_k127_10416475_14 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000002384 181.0
WLSH2_k127_10416475_15 FCD - - - 0.00000000000000000000000000000000000000000000003423 174.0
WLSH2_k127_10416475_16 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001066 172.0
WLSH2_k127_10416475_17 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.00000000000000000000000000000000000003397 146.0
WLSH2_k127_10416475_18 Phasin protein - - - 0.0000000000000000000000000000477 123.0
WLSH2_k127_10416475_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 503.0
WLSH2_k127_10416475_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 491.0
WLSH2_k127_10416475_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 463.0
WLSH2_k127_10416475_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 391.0
WLSH2_k127_10416475_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 381.0
WLSH2_k127_10416475_7 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 370.0
WLSH2_k127_10416475_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058,K03778 - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
WLSH2_k127_10416475_9 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 367.0
WLSH2_k127_10533296_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 608.0
WLSH2_k127_10533296_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
WLSH2_k127_10533296_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004931 225.0
WLSH2_k127_10533296_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000005039 187.0
WLSH2_k127_10550857_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.02e-223 718.0
WLSH2_k127_10550857_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
WLSH2_k127_10550857_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000002968 197.0
WLSH2_k127_10550857_3 Disulfide bond formation protein DsbB - - - 0.000000000000000000000000000000000000000000000000001831 187.0
WLSH2_k127_10550857_4 - - - - 0.000000000000000000000000000000000000000000796 165.0
WLSH2_k127_10550857_5 pentaerythritol trinitrate reductase activity - - - 0.00000000000000000000000000000000000006843 144.0
WLSH2_k127_10550857_6 - - - - 0.0000000000000000000000000000000000003887 143.0
WLSH2_k127_10550857_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000415 130.0
WLSH2_k127_10550857_8 RF-1 domain K15034 - - 0.000000000000000000000001731 108.0
WLSH2_k127_10550857_9 Protein of unknown function (DUF465) - - - 0.0000000000001938 73.0
WLSH2_k127_10619184_0 DHH family K07462 - - 2.679e-216 687.0
WLSH2_k127_10619184_1 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 591.0
WLSH2_k127_10619184_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 484.0
WLSH2_k127_10619184_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
WLSH2_k127_10619184_4 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000001286 248.0
WLSH2_k127_10619184_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000000775 210.0
WLSH2_k127_10619184_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002273 212.0
WLSH2_k127_10619184_7 - - - - 0.0000000009158 64.0
WLSH2_k127_10619184_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0001951 44.0
WLSH2_k127_10623274_0 Major facilitator Superfamily K08218 - - 2.489e-232 735.0
WLSH2_k127_10623274_1 Radical SAM superfamily K04069 - 1.97.1.4 3.511e-194 610.0
WLSH2_k127_10623274_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006478 249.0
WLSH2_k127_10623274_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
WLSH2_k127_10623274_4 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000009675 218.0
WLSH2_k127_10623274_5 AMMECR1 - - - 0.00000000000000000000000000000000000000000000000000000005487 198.0
WLSH2_k127_10710265_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 6.717e-270 834.0
WLSH2_k127_10710265_1 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.185e-221 694.0
WLSH2_k127_10710265_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 554.0
WLSH2_k127_10710265_3 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 409.0
WLSH2_k127_10710265_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 376.0
WLSH2_k127_10710265_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000002538 241.0
WLSH2_k127_10710265_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000002312 212.0
WLSH2_k127_10710265_7 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000001371 130.0
WLSH2_k127_10710265_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000007522 57.0
WLSH2_k127_10736513_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.923e-211 662.0
WLSH2_k127_10736513_1 transglycosylase K08309 - - 7.091e-197 635.0
WLSH2_k127_10736513_2 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000002258 126.0
WLSH2_k127_10743159_0 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 381.0
WLSH2_k127_10743159_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 354.0
WLSH2_k127_10743159_2 serine protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 350.0
WLSH2_k127_10763086_0 Tripartite tricarboxylate transporter TctA family - - - 2.332e-214 677.0
WLSH2_k127_10763086_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 355.0
WLSH2_k127_10763086_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 357.0
WLSH2_k127_10763086_3 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 316.0
WLSH2_k127_10763086_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 302.0
WLSH2_k127_10763086_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000008631 170.0
WLSH2_k127_10763086_6 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000001317 165.0
WLSH2_k127_10763086_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000001636 146.0
WLSH2_k127_10763086_9 Putative prokaryotic signal transducing protein - - - 0.000000000000003404 80.0
WLSH2_k127_10775573_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 2.86e-265 832.0
WLSH2_k127_10775573_1 Extracellular solute-binding protein - - - 4.15e-261 816.0
WLSH2_k127_10775573_10 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 287.0
WLSH2_k127_10775573_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007265 282.0
WLSH2_k127_10775573_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000001689 247.0
WLSH2_k127_10775573_13 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002946 222.0
WLSH2_k127_10775573_14 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000001542 172.0
WLSH2_k127_10775573_2 PFAM Cysteine-rich - - - 4.079e-222 699.0
WLSH2_k127_10775573_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 599.0
WLSH2_k127_10775573_4 Oligopeptide transport system permease protein OppB K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 492.0
WLSH2_k127_10775573_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 449.0
WLSH2_k127_10775573_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 424.0
WLSH2_k127_10775573_7 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 418.0
WLSH2_k127_10775573_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
WLSH2_k127_10775573_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 299.0
WLSH2_k127_10799962_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 571.0
WLSH2_k127_10799962_1 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004203 270.0
WLSH2_k127_10799962_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000115 221.0
WLSH2_k127_10804505_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000009901 155.0
WLSH2_k127_10804505_1 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001072 142.0
WLSH2_k127_10804505_2 pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000002051 151.0
WLSH2_k127_10804505_3 Type II transport protein GspH K08084 - - 0.0000000000000000000000000004625 121.0
WLSH2_k127_10804505_4 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000007768 112.0
WLSH2_k127_10804505_5 PilX N-terminal K02673 - - 0.000000000005048 73.0
WLSH2_k127_10855814_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.995e-257 805.0
WLSH2_k127_10855814_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 1.223e-199 630.0
WLSH2_k127_10855814_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5.267e-194 610.0
WLSH2_k127_10855814_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 532.0
WLSH2_k127_10855814_4 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 383.0
WLSH2_k127_10855814_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 299.0
WLSH2_k127_10855814_6 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000317 160.0
WLSH2_k127_10855814_7 Domain of Unknown Function (DUF1080) - - - 0.000002504 56.0
WLSH2_k127_10886339_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
WLSH2_k127_10886339_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 312.0
WLSH2_k127_10920655_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 607.0
WLSH2_k127_10920655_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 561.0
WLSH2_k127_10920655_10 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 286.0
WLSH2_k127_10920655_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000002511 259.0
WLSH2_k127_10920655_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009425 250.0
WLSH2_k127_10920655_13 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007528 253.0
WLSH2_k127_10920655_14 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001056 245.0
WLSH2_k127_10920655_15 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000008656 220.0
WLSH2_k127_10920655_16 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000001065 214.0
WLSH2_k127_10920655_17 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000001083 209.0
WLSH2_k127_10920655_18 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000001364 197.0
WLSH2_k127_10920655_19 - - - - 0.000000000000000000000000000000000000000000000000000000178 203.0
WLSH2_k127_10920655_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 517.0
WLSH2_k127_10920655_20 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000007491 180.0
WLSH2_k127_10920655_21 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001198 135.0
WLSH2_k127_10920655_22 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000008332 119.0
WLSH2_k127_10920655_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 492.0
WLSH2_k127_10920655_4 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 453.0
WLSH2_k127_10920655_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 423.0
WLSH2_k127_10920655_6 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 358.0
WLSH2_k127_10920655_7 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 347.0
WLSH2_k127_10920655_8 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
WLSH2_k127_10920655_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 307.0
WLSH2_k127_10922208_0 CoA binding domain - - - 1.54e-269 846.0
WLSH2_k127_10922208_1 Poly-beta-hydroxybutyrate K03821 - - 4.415e-207 659.0
WLSH2_k127_10922208_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 413.0
WLSH2_k127_10922208_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000002248 188.0
WLSH2_k127_10922208_4 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000008571 188.0
WLSH2_k127_10923715_0 Carboxysome Shell Carbonic Anhydrase - - - 3.63e-208 657.0
WLSH2_k127_10923715_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 406.0
WLSH2_k127_10923715_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000000000000000000002719 161.0
WLSH2_k127_10923715_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000001541 108.0
WLSH2_k127_10977443_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1007.0
WLSH2_k127_10977443_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 271.0
WLSH2_k127_11006065_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 5.11e-215 673.0
WLSH2_k127_11006065_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
WLSH2_k127_11006065_2 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000000000000000000000000003606 182.0
WLSH2_k127_11006065_3 - - - - 0.000000000000009246 74.0
WLSH2_k127_11054195_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 516.0
WLSH2_k127_11054195_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000002011 211.0
WLSH2_k127_11054195_2 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000002677 192.0
WLSH2_k127_11130466_0 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 437.0
WLSH2_k127_11130466_1 In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 291.0
WLSH2_k127_11130466_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000004467 217.0
WLSH2_k127_11130466_3 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000001128 162.0
WLSH2_k127_11130466_4 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00004089 48.0
WLSH2_k127_111405_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 4.562e-283 902.0
WLSH2_k127_111405_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 444.0
WLSH2_k127_111405_2 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 369.0
WLSH2_k127_111405_3 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 315.0
WLSH2_k127_111405_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000153 93.0
WLSH2_k127_11152696_0 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 298.0
WLSH2_k127_11152696_1 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000004353 173.0
WLSH2_k127_11152696_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000002345 108.0
WLSH2_k127_11152696_3 Putative zinc- or iron-chelating domain - - - 0.00000000000266 76.0
WLSH2_k127_11226471_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.33e-231 730.0
WLSH2_k127_11226471_1 Domain present in PSD-95, Dlg, and ZO-1/2. K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 490.0
WLSH2_k127_11226471_10 Tripartite tricarboxylate transporter family receptor - - - 0.00002997 47.0
WLSH2_k127_11226471_2 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 474.0
WLSH2_k127_11226471_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 444.0
WLSH2_k127_11226471_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 355.0
WLSH2_k127_11226471_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007053 255.0
WLSH2_k127_11226471_6 Enoyl-CoA hydratase/isomerase K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000004445 230.0
WLSH2_k127_11226471_7 toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000000000001711 188.0
WLSH2_k127_11226471_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000005437 194.0
WLSH2_k127_11226471_9 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000001726 137.0
WLSH2_k127_11257592_0 Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 335.0
WLSH2_k127_11257592_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000003081 207.0
WLSH2_k127_11303135_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.216e-195 616.0
WLSH2_k127_11303135_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 584.0
WLSH2_k127_11303135_2 transport system fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 576.0
WLSH2_k127_11303135_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 493.0
WLSH2_k127_11303135_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000004204 244.0
WLSH2_k127_11303135_5 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000001096 241.0
WLSH2_k127_11303135_6 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000000009649 164.0
WLSH2_k127_11303135_7 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000008355 119.0
WLSH2_k127_11348510_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 443.0
WLSH2_k127_11348510_1 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
WLSH2_k127_11348510_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000001202 215.0
WLSH2_k127_11348510_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000001327 118.0
WLSH2_k127_11348510_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000005658 66.0
WLSH2_k127_11402405_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001223 286.0
WLSH2_k127_11402405_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006223 278.0
WLSH2_k127_11402405_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001167 269.0
WLSH2_k127_11402405_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000006675 220.0
WLSH2_k127_11402405_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001625 212.0
WLSH2_k127_11402405_5 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000001241 186.0
WLSH2_k127_11402405_6 Belongs to the UPF0255 family - - - 0.00000000000000000000001008 115.0
WLSH2_k127_11402405_7 Dihydrodipicolinate synthetase family K01639 - 4.1.3.3 0.000000000000009863 81.0
WLSH2_k127_11405859_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1404.0
WLSH2_k127_11405859_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 2.89e-209 653.0
WLSH2_k127_11405859_10 - K06950 - - 0.0000000000000771 76.0
WLSH2_k127_11405859_11 Alkylhydroperoxidase AhpD family core domain-containing protein 7 - - - 0.0000003718 58.0
WLSH2_k127_11405859_12 Protein of unknown function (DUF2442) - - - 0.000003158 55.0
WLSH2_k127_11405859_13 - K11275 - - 0.00006764 51.0
WLSH2_k127_11405859_2 PFAM response regulator receiver K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 460.0
WLSH2_k127_11405859_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 435.0
WLSH2_k127_11405859_4 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 336.0
WLSH2_k127_11405859_5 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000009731 260.0
WLSH2_k127_11405859_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000002344 226.0
WLSH2_k127_11405859_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000007231 171.0
WLSH2_k127_11405859_8 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000000000001543 166.0
WLSH2_k127_11405859_9 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000005693 145.0
WLSH2_k127_11419553_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 509.0
WLSH2_k127_11419553_1 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
WLSH2_k127_11419553_2 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000006391 202.0
WLSH2_k127_11419553_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00003666 47.0
WLSH2_k127_11438184_0 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 424.0
WLSH2_k127_11438184_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644 277.0
WLSH2_k127_11438184_2 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000483 222.0
WLSH2_k127_11438184_3 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000002686 183.0
WLSH2_k127_11450547_0 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 315.0
WLSH2_k127_11450547_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000001214 92.0
WLSH2_k127_11450547_2 Phosphate-starvation-inducible E - - - 0.00000000001198 65.0
WLSH2_k127_1150893_0 abc transporter K15738 - - 7.725e-201 645.0
WLSH2_k127_1150893_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 496.0
WLSH2_k127_1150893_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
WLSH2_k127_1150893_3 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001697 282.0
WLSH2_k127_1150893_4 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 272.0
WLSH2_k127_1150893_5 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000001158 163.0
WLSH2_k127_1150893_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000278 81.0
WLSH2_k127_1150893_7 cyclic nucleotide-binding - - - 0.0000000002983 71.0
WLSH2_k127_1150893_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000003989 49.0
WLSH2_k127_1189487_0 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 350.0
WLSH2_k127_1189487_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000232 267.0
WLSH2_k127_1189487_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000008396 239.0
WLSH2_k127_1189487_3 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
WLSH2_k127_1189487_4 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000004353 210.0
WLSH2_k127_1189487_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000292 51.0
WLSH2_k127_1303468_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.635e-219 691.0
WLSH2_k127_1303468_1 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 479.0
WLSH2_k127_1303468_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000004506 189.0
WLSH2_k127_1303468_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000001182 73.0
WLSH2_k127_1303468_4 Neisseria PilC beta-propeller domain K02674 - - 0.000000002122 60.0
WLSH2_k127_1304298_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 1.33e-322 999.0
WLSH2_k127_1304298_1 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 399.0
WLSH2_k127_1304298_2 Pfam Glutaredoxin - - - 0.0000000000000000000000000000002497 131.0
WLSH2_k127_1344915_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 379.0
WLSH2_k127_1344915_1 Pfam Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001281 244.0
WLSH2_k127_1344915_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009932 251.0
WLSH2_k127_1344915_3 COG0841 Cation multidrug efflux pump K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000003585 203.0
WLSH2_k127_1344915_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000579 208.0
WLSH2_k127_1344915_5 - - - - 0.00000000000000000000000000000000000000000000000000000004842 206.0
WLSH2_k127_1344915_6 Major facilitator superfamily - - - 0.00000000000000000000000000004541 120.0
WLSH2_k127_1344915_7 Lactoylglutathione lyase and related lyases - - - 0.000000000000000006671 90.0
WLSH2_k127_148082_0 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 498.0
WLSH2_k127_148082_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000003794 93.0
WLSH2_k127_1501344_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 8.956e-224 697.0
WLSH2_k127_1501344_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 449.0
WLSH2_k127_1501344_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 354.0
WLSH2_k127_1501344_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 342.0
WLSH2_k127_1501344_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 311.0
WLSH2_k127_1501344_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000008271 266.0
WLSH2_k127_1501344_6 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000001599 156.0
WLSH2_k127_1559587_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.5e-323 1006.0
WLSH2_k127_1559587_1 AAA C-terminal domain K07478 - - 2.634e-195 617.0
WLSH2_k127_1559587_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 535.0
WLSH2_k127_1559587_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
WLSH2_k127_1559587_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000001193 234.0
WLSH2_k127_1559587_5 Phospholipid N-methyltransferase - - - 0.00000000000000000000000000000000000000000006464 166.0
WLSH2_k127_1559587_6 FecR protein - - - 0.000000000000000000000000000000000000001962 155.0
WLSH2_k127_1559587_7 - - - - 0.00000003371 58.0
WLSH2_k127_156837_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 525.0
WLSH2_k127_156837_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 410.0
WLSH2_k127_156837_2 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
WLSH2_k127_156837_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 297.0
WLSH2_k127_156837_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000001484 196.0
WLSH2_k127_1628691_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 562.0
WLSH2_k127_1628691_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 464.0
WLSH2_k127_1628691_2 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 330.0
WLSH2_k127_1628691_3 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000008905 184.0
WLSH2_k127_1674505_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 422.0
WLSH2_k127_1674505_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
WLSH2_k127_1674505_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000002859 186.0
WLSH2_k127_1674505_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000004873 149.0
WLSH2_k127_1674505_4 Maf-like protein K06287 - - 0.00000000000000000000005643 100.0
WLSH2_k127_1725111_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1314.0
WLSH2_k127_1725111_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 594.0
WLSH2_k127_1725111_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000009395 75.0
WLSH2_k127_1725111_11 pseudouridine 5'-phosphatase activity K03456,K20884 - 2.7.1.26,3.1.3.102 0.00009953 48.0
WLSH2_k127_1725111_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 576.0
WLSH2_k127_1725111_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 564.0
WLSH2_k127_1725111_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 516.0
WLSH2_k127_1725111_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 499.0
WLSH2_k127_1725111_6 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 406.0
WLSH2_k127_1725111_7 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 367.0
WLSH2_k127_1725111_8 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 311.0
WLSH2_k127_1725111_9 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000007384 132.0
WLSH2_k127_1767037_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.586e-275 858.0
WLSH2_k127_1767037_1 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 604.0
WLSH2_k127_1767037_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 515.0
WLSH2_k127_1767037_3 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
WLSH2_k127_1767037_4 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000004399 169.0
WLSH2_k127_1767037_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000009536 136.0
WLSH2_k127_1767037_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000006736 51.0
WLSH2_k127_1855657_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 2.173e-206 649.0
WLSH2_k127_1855657_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 598.0
WLSH2_k127_1855657_10 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 352.0
WLSH2_k127_1855657_11 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 332.0
WLSH2_k127_1855657_12 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 330.0
WLSH2_k127_1855657_13 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004741 272.0
WLSH2_k127_1855657_14 dna polymerase iii K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000005848 272.0
WLSH2_k127_1855657_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000002521 249.0
WLSH2_k127_1855657_16 ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000005436 164.0
WLSH2_k127_1855657_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001964 135.0
WLSH2_k127_1855657_18 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000002637 77.0
WLSH2_k127_1855657_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 552.0
WLSH2_k127_1855657_3 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 526.0
WLSH2_k127_1855657_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 505.0
WLSH2_k127_1855657_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 468.0
WLSH2_k127_1855657_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 451.0
WLSH2_k127_1855657_7 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 430.0
WLSH2_k127_1855657_8 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
WLSH2_k127_1855657_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 376.0
WLSH2_k127_1906768_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1470.0
WLSH2_k127_1906768_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 347.0
WLSH2_k127_193383_0 CBS-domain-containing membrane protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 321.0
WLSH2_k127_193383_1 CBS domain containing protein K07168 - - 0.000000000000000000002766 102.0
WLSH2_k127_193637_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
WLSH2_k127_193637_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000006431 166.0
WLSH2_k127_193637_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000002038 127.0
WLSH2_k127_1952535_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1245.0
WLSH2_k127_1952535_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.723e-219 687.0
WLSH2_k127_1952535_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 3.904e-216 678.0
WLSH2_k127_1952535_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 425.0
WLSH2_k127_1952535_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000002503 85.0
WLSH2_k127_1952535_5 Flavinator of succinate dehydrogenase K09159 - - 0.000000000001493 70.0
WLSH2_k127_201485_0 Thi4 family - - - 1.064e-228 721.0
WLSH2_k127_201485_1 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 500.0
WLSH2_k127_201485_10 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000002777 179.0
WLSH2_k127_201485_11 17 kDa surface antigen K06077 - - 0.00000000000000000000000000000000000000000000005835 173.0
WLSH2_k127_201485_12 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.0000000000000000000000000000000000000001429 154.0
WLSH2_k127_201485_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 477.0
WLSH2_k127_201485_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 400.0
WLSH2_k127_201485_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 359.0
WLSH2_k127_201485_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 319.0
WLSH2_k127_201485_6 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000006628 231.0
WLSH2_k127_201485_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000000000001939 215.0
WLSH2_k127_201485_8 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000002694 227.0
WLSH2_k127_201485_9 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000006163 192.0
WLSH2_k127_2015440_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 356.0
WLSH2_k127_2015440_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 336.0
WLSH2_k127_2015440_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 336.0
WLSH2_k127_2015440_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
WLSH2_k127_2015440_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000009283 93.0
WLSH2_k127_2097704_0 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 394.0
WLSH2_k127_2097704_1 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000001244 55.0
WLSH2_k127_2121411_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 473.0
WLSH2_k127_2121411_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
WLSH2_k127_2121411_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000008729 177.0
WLSH2_k127_2121411_3 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000007016 153.0
WLSH2_k127_2121411_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000181 119.0
WLSH2_k127_2175699_0 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 552.0
WLSH2_k127_2175699_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000008346 204.0
WLSH2_k127_2194283_0 twitching motility protein K02670 - - 4.174e-203 637.0
WLSH2_k127_2194283_1 twitching motility protein K02669 - - 7.952e-198 619.0
WLSH2_k127_2194283_10 HIRAN domain - - - 0.000000000000000000000000000000000002844 147.0
WLSH2_k127_2194283_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000005893 138.0
WLSH2_k127_2194283_12 - - - - 0.000000000000000000000007798 107.0
WLSH2_k127_2194283_2 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 462.0
WLSH2_k127_2194283_3 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 432.0
WLSH2_k127_2194283_4 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 338.0
WLSH2_k127_2194283_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001573 284.0
WLSH2_k127_2194283_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 258.0
WLSH2_k127_2194283_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000401 244.0
WLSH2_k127_2194283_8 PFAM conserved K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000263 216.0
WLSH2_k127_2194283_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000003144 192.0
WLSH2_k127_2224264_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1007.0
WLSH2_k127_2224264_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 7.227e-252 789.0
WLSH2_k127_2224264_2 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 402.0
WLSH2_k127_2224264_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 354.0
WLSH2_k127_2224264_4 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000005484 249.0
WLSH2_k127_2224264_5 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000122 246.0
WLSH2_k127_2224264_6 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000005566 209.0
WLSH2_k127_2224264_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000004478 132.0
WLSH2_k127_2224264_8 Protein of unknown function (DUF1289) K06938 - - 0.0000000001143 66.0
WLSH2_k127_2224264_9 Major Facilitator Superfamily - - - 0.00002868 47.0
WLSH2_k127_2232966_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 5.059e-294 908.0
WLSH2_k127_2232966_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001363 224.0
WLSH2_k127_2232966_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000001083 166.0
WLSH2_k127_2290215_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 6.905e-312 963.0
WLSH2_k127_2290215_1 Transport of potassium into the cell K03549 - - 2.765e-280 873.0
WLSH2_k127_2290215_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 582.0
WLSH2_k127_2290215_3 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 542.0
WLSH2_k127_2290215_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 491.0
WLSH2_k127_2290215_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 267.0
WLSH2_k127_2290215_6 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000005779 158.0
WLSH2_k127_2290215_7 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000001726 137.0
WLSH2_k127_2290215_8 Sulphur oxidation protein SoxZ - - - 0.00000000000000000000000004887 110.0
WLSH2_k127_2360638_0 Aconitase family (aconitate hydratase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 440.0
WLSH2_k127_2360638_1 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 380.0
WLSH2_k127_2360638_2 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 364.0
WLSH2_k127_2360638_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000004647 253.0
WLSH2_k127_2360638_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000002435 72.0
WLSH2_k127_2425984_0 COG0534 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 425.0
WLSH2_k127_2425984_1 Amidohydrolase K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 367.0
WLSH2_k127_2425984_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 356.0
WLSH2_k127_2425984_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 342.0
WLSH2_k127_2425984_4 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 344.0
WLSH2_k127_2425984_5 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
WLSH2_k127_2425984_6 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
WLSH2_k127_2425984_7 - - - - 0.0000000000000000000000000000000000000000000000005405 188.0
WLSH2_k127_2425984_8 FCD - - - 0.00000000000000000000000000000007656 133.0
WLSH2_k127_2510567_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 359.0
WLSH2_k127_2510567_1 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003897 258.0
WLSH2_k127_2510567_2 2OG-Fe(II) oxygenase superfamily K15429 - 2.1.1.228 0.0000000000000000000003976 107.0
WLSH2_k127_2510567_3 Tripartite tricarboxylate transporter family receptor - - - 0.00006142 47.0
WLSH2_k127_2534061_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004845 271.0
WLSH2_k127_2534061_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000001462 201.0
WLSH2_k127_2534061_2 Virulence factor BrkB K07058 - - 0.00000000007725 64.0
WLSH2_k127_2534061_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000004338 58.0
WLSH2_k127_2534061_4 Phospholipase_D-nuclease N-terminal - - - 0.000009077 56.0
WLSH2_k127_2551018_0 CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 1.985e-229 730.0
WLSH2_k127_2551018_1 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 399.0
WLSH2_k127_2551018_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 345.0
WLSH2_k127_2551018_3 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 279.0
WLSH2_k127_2551018_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000627 192.0
WLSH2_k127_2551018_5 protein conserved in bacteria - - - 0.00000000000000001002 84.0
WLSH2_k127_2564822_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 539.0
WLSH2_k127_2564822_1 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 388.0
WLSH2_k127_2564822_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 319.0
WLSH2_k127_2564822_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 319.0
WLSH2_k127_2564822_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 298.0
WLSH2_k127_2564822_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005165 274.0
WLSH2_k127_2564822_6 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000001183 229.0
WLSH2_k127_2564822_7 - - - - 0.000000002731 64.0
WLSH2_k127_2625313_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.218e-216 686.0
WLSH2_k127_2625313_1 Protein of unknown function (DUF4080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 607.0
WLSH2_k127_2625313_2 alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 449.0
WLSH2_k127_2625313_3 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000000002784 198.0
WLSH2_k127_2625313_4 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000006091 193.0
WLSH2_k127_2625313_5 membrane - - - 0.0000000000000000000000000000000000000000000000000209 186.0
WLSH2_k127_2625313_6 NUDIX domain - - - 0.000000000000000000000000000000000000000000000001704 179.0
WLSH2_k127_2625313_7 - - - - 0.000000000000000000000000000000002448 132.0
WLSH2_k127_2625313_8 S4 RNA-binding domain - - - 0.00000000000000000000000000009021 125.0
WLSH2_k127_2625313_9 alkaline phosphatase K01113 - 3.1.3.1 0.000000000000000003764 85.0
WLSH2_k127_2652620_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.305e-230 733.0
WLSH2_k127_2652620_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 282.0
WLSH2_k127_2652620_2 Enoyl-CoA hydratase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
WLSH2_k127_2652620_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000006677 227.0
WLSH2_k127_26674_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000001593 207.0
WLSH2_k127_26674_1 Dak2 K07030 - - 0.0000000000000000000000000000000000000000000000000003478 194.0
WLSH2_k127_26674_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.000000000000000000000000000003143 124.0
WLSH2_k127_2670382_0 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 597.0
WLSH2_k127_2670382_1 4Fe-4S dicluster domain K07307 - - 0.00000000007374 64.0
WLSH2_k127_2691982_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1218.0
WLSH2_k127_2691982_1 nitrite transporter K02575 - - 1.386e-277 861.0
WLSH2_k127_2691982_10 OmpW family K07275 - - 0.000000000000000000000000000000000000000000000000000002168 197.0
WLSH2_k127_2691982_11 cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000000001378 89.0
WLSH2_k127_2691982_2 cation transport ATPase K01533 - 3.6.3.4 3.053e-253 806.0
WLSH2_k127_2691982_3 nitrite transmembrane transporter activity K02575 - - 1.757e-231 723.0
WLSH2_k127_2691982_4 PFAM Major Facilitator Superfamily K02575 - - 7.201e-223 697.0
WLSH2_k127_2691982_5 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 540.0
WLSH2_k127_2691982_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 360.0
WLSH2_k127_2691982_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 323.0
WLSH2_k127_2691982_8 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007435 272.0
WLSH2_k127_2691982_9 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000174 246.0
WLSH2_k127_2746971_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.412e-217 681.0
WLSH2_k127_2746971_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 458.0
WLSH2_k127_2843076_0 CoA-transferase family III - - - 3.294e-201 636.0
WLSH2_k127_2843076_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 562.0
WLSH2_k127_2843076_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000009257 81.0
WLSH2_k127_2843076_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 533.0
WLSH2_k127_2843076_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
WLSH2_k127_2843076_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
WLSH2_k127_2843076_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 302.0
WLSH2_k127_2843076_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 301.0
WLSH2_k127_2843076_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000034 268.0
WLSH2_k127_2843076_8 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
WLSH2_k127_2843076_9 uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center K05297 - 1.18.1.1 0.0000000000000000000000004275 108.0
WLSH2_k127_2888823_0 GntP family permease - - - 5.087e-218 690.0
WLSH2_k127_2888823_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 497.0
WLSH2_k127_2888823_2 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 441.0
WLSH2_k127_2888823_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 287.0
WLSH2_k127_2888823_4 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.00000000000000000000000000000001918 134.0
WLSH2_k127_2902438_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 524.0
WLSH2_k127_2902438_1 Methyl-transferase K06983 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 375.0
WLSH2_k127_2902438_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 304.0
WLSH2_k127_2948989_0 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 311.0
WLSH2_k127_2948989_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000002967 231.0
WLSH2_k127_2948989_2 phosphinothricin N-acetyltransferase activity K03830 - - 0.0000000000000000001343 90.0
WLSH2_k127_2948989_3 protein conserved in bacteria - - - 0.0000000000000001366 85.0
WLSH2_k127_2948989_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000005768 64.0
WLSH2_k127_2964020_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
WLSH2_k127_2964020_1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 323.0
WLSH2_k127_2990153_0 TonB dependent receptor K02014 - - 3.711e-210 678.0
WLSH2_k127_2990153_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 378.0
WLSH2_k127_2990153_2 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000000000006654 160.0
WLSH2_k127_2990153_3 - - - - 0.0000000000000000371 83.0
WLSH2_k127_3013756_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.764e-201 637.0
WLSH2_k127_3013756_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 366.0
WLSH2_k127_3013756_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000003814 182.0
WLSH2_k127_3013756_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000002255 160.0
WLSH2_k127_3013756_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000007253 144.0
WLSH2_k127_3013756_5 Bacterial SH3 domain - - - 0.000000000000000000000000000000000059 138.0
WLSH2_k127_3013756_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000003829 135.0
WLSH2_k127_3013756_7 peptidase, M23 - - - 0.000000000000000000000000000006266 131.0
WLSH2_k127_3013756_8 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000004769 93.0
WLSH2_k127_3038388_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 390.0
WLSH2_k127_3038388_1 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000003001 236.0
WLSH2_k127_3038388_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000004562 214.0
WLSH2_k127_3038388_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000005075 187.0
WLSH2_k127_3038388_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000004441 142.0
WLSH2_k127_304870_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 553.0
WLSH2_k127_304870_1 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000000000000000000000001327 197.0
WLSH2_k127_304870_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000001562 70.0
WLSH2_k127_3065988_0 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 586.0
WLSH2_k127_3065988_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 500.0
WLSH2_k127_3065988_2 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 428.0
WLSH2_k127_3065988_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000001648 139.0
WLSH2_k127_3065988_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000005425 129.0
WLSH2_k127_3065988_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000007041 93.0
WLSH2_k127_3141950_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.033e-203 641.0
WLSH2_k127_3141950_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 506.0
WLSH2_k127_3141950_10 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003665 256.0
WLSH2_k127_3141950_11 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 254.0
WLSH2_k127_3141950_12 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 222.0
WLSH2_k127_3141950_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
WLSH2_k127_3141950_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000001944 202.0
WLSH2_k127_3141950_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000003736 174.0
WLSH2_k127_3141950_16 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001574 119.0
WLSH2_k127_3141950_17 Transmembrane anti-sigma factor - - - 0.000000006787 58.0
WLSH2_k127_3141950_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 480.0
WLSH2_k127_3141950_3 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 482.0
WLSH2_k127_3141950_4 Aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 407.0
WLSH2_k127_3141950_5 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 363.0
WLSH2_k127_3141950_6 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 295.0
WLSH2_k127_3141950_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
WLSH2_k127_3141950_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
WLSH2_k127_3141950_9 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001446 263.0
WLSH2_k127_3189468_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 9.956e-281 871.0
WLSH2_k127_3189468_1 DNA helicase K03654 - 3.6.4.12 3.512e-276 861.0
WLSH2_k127_3189468_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 325.0
WLSH2_k127_3189468_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001406 274.0
WLSH2_k127_3189468_12 succinate dehydrogenase K00247 - - 0.000000000000000000000000000000000000000008732 158.0
WLSH2_k127_3189468_13 succinate dehydrogenase K00246 - - 0.00000000000000000000000000000001907 130.0
WLSH2_k127_3189468_14 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000005714 120.0
WLSH2_k127_3189468_16 Belongs to the ompA family K03286 - - 0.000000005845 66.0
WLSH2_k127_3189468_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 582.0
WLSH2_k127_3189468_3 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101 - 1.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 478.0
WLSH2_k127_3189468_4 Tartrate K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 456.0
WLSH2_k127_3189468_5 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 398.0
WLSH2_k127_3189468_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 374.0
WLSH2_k127_3189468_7 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 369.0
WLSH2_k127_3189468_8 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 366.0
WLSH2_k127_3189468_9 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 325.0
WLSH2_k127_3284602_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.572e-241 756.0
WLSH2_k127_3284602_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.251e-205 643.0
WLSH2_k127_3284602_10 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 322.0
WLSH2_k127_3284602_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002275 253.0
WLSH2_k127_3284602_12 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000004503 183.0
WLSH2_k127_3284602_13 - - - - 0.000000000000000000000000000000000000000004892 169.0
WLSH2_k127_3284602_14 transferase hexapeptide - - - 0.00000000000000000000000000000000000000006253 152.0
WLSH2_k127_3284602_15 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000004405 151.0
WLSH2_k127_3284602_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.157e-194 620.0
WLSH2_k127_3284602_3 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 464.0
WLSH2_k127_3284602_4 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 468.0
WLSH2_k127_3284602_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 449.0
WLSH2_k127_3284602_6 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 450.0
WLSH2_k127_3284602_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 448.0
WLSH2_k127_3284602_8 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 411.0
WLSH2_k127_3284602_9 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 326.0
WLSH2_k127_3395034_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 570.0
WLSH2_k127_3395034_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 487.0
WLSH2_k127_3395034_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
WLSH2_k127_3395034_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002453 252.0
WLSH2_k127_3395034_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001811 246.0
WLSH2_k127_3395034_5 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.0000000000000000000000000000000000000001962 161.0
WLSH2_k127_3395034_6 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000009459 137.0
WLSH2_k127_3395034_7 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000001155 136.0
WLSH2_k127_3395034_8 protein conserved in bacteria - - - 0.000000002118 61.0
WLSH2_k127_3452272_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1344.0
WLSH2_k127_3452272_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1072.0
WLSH2_k127_3452272_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 588.0
WLSH2_k127_3452272_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 451.0
WLSH2_k127_3452272_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 353.0
WLSH2_k127_3452272_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 306.0
WLSH2_k127_3452272_6 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000332 266.0
WLSH2_k127_3452272_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003253 253.0
WLSH2_k127_3452272_8 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000000000000000000000000002157 198.0
WLSH2_k127_3452272_9 CRS1_YhbY K07574 - - 0.000000000000000000000000000000366 126.0
WLSH2_k127_3547208_0 O-methyltransferase activity - - - 2.617e-222 707.0
WLSH2_k127_3547208_1 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 453.0
WLSH2_k127_3547208_2 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
WLSH2_k127_3547208_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000001308 136.0
WLSH2_k127_3574040_0 Radical SAM K01012 - 2.8.1.6 4.159e-198 621.0
WLSH2_k127_3574040_1 SMART Elongator protein 3 MiaB NifB K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 516.0
WLSH2_k127_3574040_10 - - - - 0.000000000000000000000000000000000006029 140.0
WLSH2_k127_3574040_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 513.0
WLSH2_k127_3574040_3 lipoate-protein ligase A K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 494.0
WLSH2_k127_3574040_4 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 378.0
WLSH2_k127_3574040_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002882 263.0
WLSH2_k127_3574040_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000007366 209.0
WLSH2_k127_3574040_7 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000007559 194.0
WLSH2_k127_3574040_8 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000000006146 185.0
WLSH2_k127_3574040_9 PFAM biotin lipoate A B protein ligase - - - 0.0000000000000000000000000000000000000000000000002457 187.0
WLSH2_k127_3575618_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 7.299e-299 931.0
WLSH2_k127_3575618_1 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 2.275e-270 852.0
WLSH2_k127_3575618_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.591e-218 696.0
WLSH2_k127_3575618_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 321.0
WLSH2_k127_3575618_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005296 276.0
WLSH2_k127_3575618_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000001801 132.0
WLSH2_k127_3575618_6 heavy metal transport detoxification protein K07213 - - 0.00000000000005675 74.0
WLSH2_k127_3579868_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 5.139e-314 996.0
WLSH2_k127_3579868_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.987e-195 627.0
WLSH2_k127_3579868_2 amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
WLSH2_k127_3579868_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 322.0
WLSH2_k127_3579868_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
WLSH2_k127_3579868_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 309.0
WLSH2_k127_3579868_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002632 249.0
WLSH2_k127_3579868_7 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000004038 171.0
WLSH2_k127_3579868_8 universal stress protein - - - 0.000000006463 58.0
WLSH2_k127_3762930_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.676e-277 856.0
WLSH2_k127_3762930_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 548.0
WLSH2_k127_3769586_0 Methionine synthase K00548 - 2.1.1.13 0.0 1808.0
WLSH2_k127_3769586_1 phytanoyl-CoA dioxygenase K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 288.0
WLSH2_k127_3769586_2 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000006967 209.0
WLSH2_k127_3769586_3 CAAX amino Terminal protease family protein K07052 - - 0.000000000000000000000000000000000000000000000000000007182 200.0
WLSH2_k127_3769586_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000103 122.0
WLSH2_k127_3778037_0 Patched family - - - 0.0 1026.0
WLSH2_k127_3778037_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000007899 141.0
WLSH2_k127_3917427_0 elongation factor G K02355 - - 2.064e-305 953.0
WLSH2_k127_3917427_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000007793 218.0
WLSH2_k127_3917427_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001807 197.0
WLSH2_k127_3917427_3 Cadmium resistance transporter - - - 0.00000000000000000000000000000000000000000000000000000235 198.0
WLSH2_k127_3917427_4 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000003623 189.0
WLSH2_k127_3917427_5 Asp Glu hydantoin racemase - - - 0.000000000000000000000000000000000000000000323 166.0
WLSH2_k127_3917427_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.00000000000000000000005722 106.0
WLSH2_k127_3917427_8 decarboxylase K01607 - 4.1.1.44 0.000000001551 61.0
WLSH2_k127_4153483_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.629e-307 954.0
WLSH2_k127_4153483_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 385.0
WLSH2_k127_4153483_10 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000008041 66.0
WLSH2_k127_4153483_2 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 331.0
WLSH2_k127_4153483_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006818 270.0
WLSH2_k127_4153483_4 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
WLSH2_k127_4153483_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
WLSH2_k127_4153483_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000001758 209.0
WLSH2_k127_4153483_7 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000004119 182.0
WLSH2_k127_4153483_8 thymidine phosphorylase K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000002288 168.0
WLSH2_k127_4153483_9 subunit of a heme lyase K02200 - - 0.0000000000000000004558 89.0
WLSH2_k127_4165291_0 SNARE associated Golgi protein - - - 0.0 1035.0
WLSH2_k127_4165291_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 624.0
WLSH2_k127_4165291_10 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000003846 191.0
WLSH2_k127_4165291_11 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000003555 193.0
WLSH2_k127_4165291_12 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000004377 180.0
WLSH2_k127_4165291_13 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000001506 149.0
WLSH2_k127_4165291_2 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 567.0
WLSH2_k127_4165291_3 sulfide dehydrogenase K05301 - 1.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 507.0
WLSH2_k127_4165291_4 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 477.0
WLSH2_k127_4165291_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 362.0
WLSH2_k127_4165291_6 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 317.0
WLSH2_k127_4165291_7 Glycosyl transferase group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005678 275.0
WLSH2_k127_4165291_8 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003498 267.0
WLSH2_k127_4165291_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000001099 199.0
WLSH2_k127_4195650_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 326.0
WLSH2_k127_4195650_1 DSBA-like thioredoxin domain K07396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 294.0
WLSH2_k127_4195650_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 290.0
WLSH2_k127_4195650_3 transcriptional regulators - - - 0.0000000000000000000000000000000000000000004293 160.0
WLSH2_k127_4195650_4 Sulfurtransferase TusA K04085 - - 0.0000000000000000000000000000000000000008049 148.0
WLSH2_k127_4195650_5 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000003579 96.0
WLSH2_k127_4195650_6 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 0.000007294 54.0
WLSH2_k127_4221580_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 364.0
WLSH2_k127_4221580_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000006287 188.0
WLSH2_k127_4221580_2 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000004098 175.0
WLSH2_k127_4221580_3 PFAM NLP P60 protein - - - 0.00000000000000000000000000000000000000009729 155.0
WLSH2_k127_4221580_4 electron transfer activity K03737,K05337 - 1.2.7.1 0.0007277 53.0
WLSH2_k127_4266160_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 1.297e-258 811.0
WLSH2_k127_4266160_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 605.0
WLSH2_k127_4266160_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003306 249.0
WLSH2_k127_4266160_11 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
WLSH2_k127_4266160_12 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000002344 160.0
WLSH2_k127_4266160_13 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000004399 151.0
WLSH2_k127_4266160_14 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000005664 142.0
WLSH2_k127_4266160_15 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000009136 121.0
WLSH2_k127_4266160_16 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000005095 81.0
WLSH2_k127_4266160_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 465.0
WLSH2_k127_4266160_3 ABC-type dipeptide oligopeptide nickel transport system, permease component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 436.0
WLSH2_k127_4266160_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 383.0
WLSH2_k127_4266160_5 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
WLSH2_k127_4266160_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 325.0
WLSH2_k127_4266160_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 324.0
WLSH2_k127_4266160_8 Taurine catabolism dioxygenase TauD, TfdA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 275.0
WLSH2_k127_4266160_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000586 274.0
WLSH2_k127_4272793_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 613.0
WLSH2_k127_4272793_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 581.0
WLSH2_k127_4272793_10 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000002445 195.0
WLSH2_k127_4272793_11 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000002299 121.0
WLSH2_k127_4272793_12 transporter antisigma-factor antagonist STAS K07122 - - 0.0000000000000000001218 92.0
WLSH2_k127_4272793_13 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000001632 70.0
WLSH2_k127_4272793_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 441.0
WLSH2_k127_4272793_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 416.0
WLSH2_k127_4272793_4 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 367.0
WLSH2_k127_4272793_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 362.0
WLSH2_k127_4272793_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 347.0
WLSH2_k127_4272793_7 Histidine biosynthesis bifunctional protein HisB K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 318.0
WLSH2_k127_4272793_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 310.0
WLSH2_k127_4272793_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000002767 237.0
WLSH2_k127_428062_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003535 267.0
WLSH2_k127_428062_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K18612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003366 265.0
WLSH2_k127_428062_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000008202 241.0
WLSH2_k127_428062_3 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032,K13892 - - 0.000001412 49.0
WLSH2_k127_436813_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1284.0
WLSH2_k127_436813_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 1.253e-219 688.0
WLSH2_k127_436813_10 - - - - 0.0000000000000000000000000001091 121.0
WLSH2_k127_436813_11 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000003113 55.0
WLSH2_k127_436813_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 568.0
WLSH2_k127_436813_3 Alpha beta hydrolase K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 392.0
WLSH2_k127_436813_4 AIR synthase related protein, N-terminal domain K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000622 252.0
WLSH2_k127_436813_5 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000002524 213.0
WLSH2_k127_436813_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000001101 205.0
WLSH2_k127_436813_7 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000000001099 154.0
WLSH2_k127_436813_8 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000001615 146.0
WLSH2_k127_436813_9 - - - - 0.0000000000000000000000000000000009139 133.0
WLSH2_k127_445170_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 3.472e-196 620.0
WLSH2_k127_445170_1 Ectoine hydroxylase K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 382.0
WLSH2_k127_445170_2 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000008055 201.0
WLSH2_k127_445170_3 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.0000000000000000000000004278 107.0
WLSH2_k127_445170_4 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000003371 58.0
WLSH2_k127_4499810_0 Protein of unknown function - - - 0.0 1105.0
WLSH2_k127_4499810_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 6.625e-314 986.0
WLSH2_k127_4499810_10 Zinc-finger domain - - - 0.000000000000000000000000000001244 121.0
WLSH2_k127_4499810_2 modulator of DNA gyrase K03568 - - 5.104e-239 745.0
WLSH2_k127_4499810_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 524.0
WLSH2_k127_4499810_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 503.0
WLSH2_k127_4499810_5 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 444.0
WLSH2_k127_4499810_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 408.0
WLSH2_k127_4499810_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 381.0
WLSH2_k127_4499810_8 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002788 284.0
WLSH2_k127_4499810_9 SnoaL-like domain - - - 0.000000000000000000000000000000000001113 143.0
WLSH2_k127_4606509_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 609.0
WLSH2_k127_4606509_1 Chorismate lyase K03181 - 4.1.3.40 0.000000000000004033 79.0
WLSH2_k127_4759071_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.982e-318 982.0
WLSH2_k127_4759071_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 400.0
WLSH2_k127_4759071_10 Domain of unknown function (DUF4845) - - - 0.0000000000000000001889 92.0
WLSH2_k127_4759071_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 352.0
WLSH2_k127_4759071_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 331.0
WLSH2_k127_4759071_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 299.0
WLSH2_k127_4759071_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
WLSH2_k127_4759071_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
WLSH2_k127_4759071_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000003713 157.0
WLSH2_k127_4759071_8 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000003496 148.0
WLSH2_k127_4759071_9 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.00000000000000000005144 93.0
WLSH2_k127_477461_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 451.0
WLSH2_k127_477461_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 385.0
WLSH2_k127_477461_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
WLSH2_k127_477461_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 295.0
WLSH2_k127_477461_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002146 240.0
WLSH2_k127_477461_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000004376 159.0
WLSH2_k127_477461_6 Domain of unknown function (DUF4340) - - - 0.0000000000002604 82.0
WLSH2_k127_484516_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.231e-199 630.0
WLSH2_k127_484516_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 606.0
WLSH2_k127_484516_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000003733 206.0
WLSH2_k127_484516_3 - - - - 0.000000000000000000000000000000118 128.0
WLSH2_k127_4871089_0 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 319.0
WLSH2_k127_4871089_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
WLSH2_k127_4871089_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000452 203.0
WLSH2_k127_4871089_3 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000003179 179.0
WLSH2_k127_4871089_4 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000004843 162.0
WLSH2_k127_4871089_5 TIGRFAM TonB family protein K03646 - - 0.0000000000000000000000000003015 124.0
WLSH2_k127_488265_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
WLSH2_k127_488265_1 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000345 283.0
WLSH2_k127_488265_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000006936 199.0
WLSH2_k127_488265_3 Belongs to the UPF0250 family K09158 - - 0.00000000000001856 73.0
WLSH2_k127_4955272_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 1.035e-290 902.0
WLSH2_k127_4955272_1 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 444.0
WLSH2_k127_4955272_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 382.0
WLSH2_k127_4955272_3 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
WLSH2_k127_4955272_4 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
WLSH2_k127_4955272_5 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000003887 118.0
WLSH2_k127_4955272_6 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K19168 - - 0.0000000000000001521 85.0
WLSH2_k127_4955272_7 Domain of unknown function (DUF4936) - - - 0.00000000000006547 76.0
WLSH2_k127_4955272_8 - - - - 0.00000000002967 66.0
WLSH2_k127_4955272_9 - - - - 0.00003401 48.0
WLSH2_k127_4992336_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.128e-244 769.0
WLSH2_k127_4992336_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 357.0
WLSH2_k127_4992336_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 304.0
WLSH2_k127_4992336_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002219 266.0
WLSH2_k127_4992336_4 Protein of unknown function (DUF1178) - - - 0.0000000000000009243 79.0
WLSH2_k127_4992336_5 - - - - 0.00000002355 62.0
WLSH2_k127_504992_0 Tripartite tricarboxylate transporter TctA family K07793 - - 9.292e-229 717.0
WLSH2_k127_504992_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.737e-214 683.0
WLSH2_k127_504992_10 Asp Glu hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000003936 218.0
WLSH2_k127_504992_11 Water Stress and Hypersensitive response - - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
WLSH2_k127_504992_12 Rhodanese - - - 0.000000000000000000000000000000000000000000000000001126 197.0
WLSH2_k127_504992_13 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000002472 166.0
WLSH2_k127_504992_15 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000003189 127.0
WLSH2_k127_504992_16 MmgE/PrpD family - - - 0.00000000000000000000002291 102.0
WLSH2_k127_504992_17 Amidohydrolase - - - 0.0000001614 58.0
WLSH2_k127_504992_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 441.0
WLSH2_k127_504992_3 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
WLSH2_k127_504992_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
WLSH2_k127_504992_5 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 304.0
WLSH2_k127_504992_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 298.0
WLSH2_k127_504992_7 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
WLSH2_k127_504992_8 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000008756 248.0
WLSH2_k127_504992_9 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
WLSH2_k127_5094421_0 Major Facilitator Superfamily - - - 2.441e-213 668.0
WLSH2_k127_5094421_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 6.71e-198 619.0
WLSH2_k127_5094421_10 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000433 211.0
WLSH2_k127_5094421_11 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000006991 209.0
WLSH2_k127_5094421_12 SMART regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000001852 134.0
WLSH2_k127_5094421_13 - - - - 0.00000000000000000000003472 105.0
WLSH2_k127_5094421_14 - - - - 0.000008339 52.0
WLSH2_k127_5094421_2 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 535.0
WLSH2_k127_5094421_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 522.0
WLSH2_k127_5094421_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 490.0
WLSH2_k127_5094421_5 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 441.0
WLSH2_k127_5094421_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 437.0
WLSH2_k127_5094421_7 SMART transcription factor jumonji jmjC domain protein K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 383.0
WLSH2_k127_5094421_8 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 326.0
WLSH2_k127_5094421_9 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000001606 233.0
WLSH2_k127_5106648_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 4.147e-207 650.0
WLSH2_k127_5106648_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 406.0
WLSH2_k127_5106648_10 Thioredoxin domain - - - 0.000000000000000000000000000000001716 132.0
WLSH2_k127_5106648_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000001877 91.0
WLSH2_k127_5106648_12 Adenosylcobalamin biosynthesis, ATP cob(I)alamin adenosyltransferase, EutT PduO type K00798 - 2.5.1.17 0.00000508 54.0
WLSH2_k127_5106648_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 364.0
WLSH2_k127_5106648_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 309.0
WLSH2_k127_5106648_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 299.0
WLSH2_k127_5106648_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003532 270.0
WLSH2_k127_5106648_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 273.0
WLSH2_k127_5106648_7 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
WLSH2_k127_5106648_8 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000002916 181.0
WLSH2_k127_5106648_9 TRANSCRIPTIONal - - - 0.0000000000000000000000000000000000000000000004144 174.0
WLSH2_k127_5143326_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 547.0
WLSH2_k127_5143326_1 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
WLSH2_k127_5143326_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 297.0
WLSH2_k127_5143326_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 297.0
WLSH2_k127_5143326_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000305 111.0
WLSH2_k127_5143326_5 Protein of unknown function (DUF3567) - - - 0.00000000003129 70.0
WLSH2_k127_5143326_6 PFAM EamA-like transporter family - - - 0.0000000001802 63.0
WLSH2_k127_517249_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1236.0
WLSH2_k127_517249_1 Helicase K03657 - 3.6.4.12 9.766e-316 982.0
WLSH2_k127_517249_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 414.0
WLSH2_k127_517249_3 - - - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
WLSH2_k127_517249_4 Protein of unknown function (DUF2782) - - - 0.000000000000000000000000000000006094 130.0
WLSH2_k127_517249_5 Methyltransferase domain - - - 0.0000000001082 65.0
WLSH2_k127_5262247_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.918e-206 654.0
WLSH2_k127_5262247_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 467.0
WLSH2_k127_5262247_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001893 265.0
WLSH2_k127_5262247_3 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000008555 126.0
WLSH2_k127_5262247_4 3-carboxy-cis,cis-muconate cycloisomerase K01756 - 4.3.2.2 0.0000000000000003054 79.0
WLSH2_k127_5262247_5 MFS_1 like family - - - 0.0009163 43.0
WLSH2_k127_5277533_0 phosphonate metabolism protein PhnM K06162 - 3.6.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 541.0
WLSH2_k127_5277533_1 beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 332.0
WLSH2_k127_5277533_2 phosphonate C-P lyase system protein PhnL K05780 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 302.0
WLSH2_k127_5277533_3 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 - 2.7.4.23 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
WLSH2_k127_5277533_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001321 170.0
WLSH2_k127_5300411_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 2.629e-313 973.0
WLSH2_k127_5300411_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
WLSH2_k127_5343049_0 ribonuclease, Rne Rng family K08301 - - 6.827e-238 748.0
WLSH2_k127_5343049_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 328.0
WLSH2_k127_5343049_2 Maf-like protein K06287 - - 0.000000000000000000000000002159 113.0
WLSH2_k127_538758_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 3.518e-219 684.0
WLSH2_k127_538758_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.906e-218 690.0
WLSH2_k127_538758_10 Redoxin domain protein - - - 0.0000000000000000000000000000000000001873 145.0
WLSH2_k127_538758_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000004225 114.0
WLSH2_k127_538758_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 560.0
WLSH2_k127_538758_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 531.0
WLSH2_k127_538758_4 Chromate Ion Transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 497.0
WLSH2_k127_538758_5 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 438.0
WLSH2_k127_538758_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005897 257.0
WLSH2_k127_538758_7 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000002401 235.0
WLSH2_k127_538758_8 PFAM 20S proteasome, A and B subunits - - - 0.00000000000000000000000000000000000000000000000000000000000001215 220.0
WLSH2_k127_538758_9 Protein of unknown function (DUF1255) - - - 0.0000000000000000000000000000000000000000003205 160.0
WLSH2_k127_557484_0 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 466.0
WLSH2_k127_557484_1 protein conserved in bacteria K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000001833 244.0
WLSH2_k127_557484_2 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
WLSH2_k127_557484_3 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000935 236.0
WLSH2_k127_557484_4 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000007758 52.0
WLSH2_k127_5585446_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1448.0
WLSH2_k127_5585446_1 Pfam Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 485.0
WLSH2_k127_5585446_10 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008645 256.0
WLSH2_k127_5585446_11 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008214 250.0
WLSH2_k127_5585446_12 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
WLSH2_k127_5585446_13 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000008389 229.0
WLSH2_k127_5585446_14 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000004306 192.0
WLSH2_k127_5585446_15 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000001155 196.0
WLSH2_k127_5585446_16 Peptidase M15 - - - 0.000000000000000000000000000000002383 133.0
WLSH2_k127_5585446_17 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000001795 113.0
WLSH2_k127_5585446_18 rubredoxin - GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 - 0.0000000000000000000000009152 110.0
WLSH2_k127_5585446_19 Sulfatase K01133 - 3.1.6.6 0.00000009246 55.0
WLSH2_k127_5585446_2 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 435.0
WLSH2_k127_5585446_20 - - - - 0.0000009057 61.0
WLSH2_k127_5585446_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 433.0
WLSH2_k127_5585446_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 384.0
WLSH2_k127_5585446_5 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
WLSH2_k127_5585446_6 Formate nitrite K02598,K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 350.0
WLSH2_k127_5585446_7 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 327.0
WLSH2_k127_5585446_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 297.0
WLSH2_k127_5585446_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001968 285.0
WLSH2_k127_5601488_0 Dehydrogenase K15515 - 1.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 565.0
WLSH2_k127_5601488_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 512.0
WLSH2_k127_5601488_2 - - - - 0.000000000000000000000000000000000000000000000008927 177.0
WLSH2_k127_5601488_4 Protein conserved in bacteria K07793 - - 0.000000000000000002428 85.0
WLSH2_k127_5630133_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001977 237.0
WLSH2_k127_5630133_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000001663 106.0
WLSH2_k127_5689843_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 5.361e-221 700.0
WLSH2_k127_5689843_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 440.0
WLSH2_k127_5689843_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 379.0
WLSH2_k127_5689843_3 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 327.0
WLSH2_k127_5689843_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002022 257.0
WLSH2_k127_5689843_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
WLSH2_k127_5689843_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000002343 215.0
WLSH2_k127_5689843_7 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000004303 184.0
WLSH2_k127_5708489_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 9.411e-213 670.0
WLSH2_k127_5708489_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 543.0
WLSH2_k127_5708489_2 Domain of unknown function (DUF4124) - - - 0.00000000000001721 80.0
WLSH2_k127_5738629_0 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 469.0
WLSH2_k127_5738629_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 453.0
WLSH2_k127_5738629_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 317.0
WLSH2_k127_5738629_3 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000001284 174.0
WLSH2_k127_5738629_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000004254 151.0
WLSH2_k127_5752428_0 PFAM Radical SAM K04069 - 1.97.1.4 2.518e-197 621.0
WLSH2_k127_5752428_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 349.0
WLSH2_k127_5752428_2 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000004257 174.0
WLSH2_k127_5752428_3 pfam ammecr1 - - - 0.00000000000000000000000000000005821 127.0
WLSH2_k127_5752428_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.00000000000000000000002081 99.0
WLSH2_k127_5863287_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 582.0
WLSH2_k127_5863287_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 504.0
WLSH2_k127_5863287_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 243.0
WLSH2_k127_5863287_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001675 243.0
WLSH2_k127_5863287_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
WLSH2_k127_5863287_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000007817 219.0
WLSH2_k127_5863287_6 Pfam Ankyrin K06867 - - 0.000000000000005704 84.0
WLSH2_k127_5881182_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 6.215e-321 998.0
WLSH2_k127_5881182_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.624e-214 676.0
WLSH2_k127_5881182_10 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
WLSH2_k127_5881182_11 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000004062 241.0
WLSH2_k127_5881182_12 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
WLSH2_k127_5881182_13 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001102 202.0
WLSH2_k127_5881182_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001547 171.0
WLSH2_k127_5881182_15 mRNA catabolic process - - - 0.000000000000000000000000000000000007174 140.0
WLSH2_k127_5881182_16 - - - - 0.0000000000000000000000004182 114.0
WLSH2_k127_5881182_17 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000001193 85.0
WLSH2_k127_5881182_2 Carboxyl transferase domain - - - 5.922e-211 666.0
WLSH2_k127_5881182_3 Biotin carboxylase C-terminal domain K01941 - 6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 588.0
WLSH2_k127_5881182_4 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 551.0
WLSH2_k127_5881182_5 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 505.0
WLSH2_k127_5881182_6 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 482.0
WLSH2_k127_5881182_7 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 457.0
WLSH2_k127_5881182_8 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 357.0
WLSH2_k127_5881182_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
WLSH2_k127_6028343_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.889e-273 853.0
WLSH2_k127_6028343_1 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 4.382e-222 698.0
WLSH2_k127_6028343_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 578.0
WLSH2_k127_6028343_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 422.0
WLSH2_k127_6028343_4 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 291.0
WLSH2_k127_6028343_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000009215 189.0
WLSH2_k127_6028343_6 preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000006906 133.0
WLSH2_k127_6028343_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000002191 126.0
WLSH2_k127_604143_0 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
WLSH2_k127_604143_1 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000001263 206.0
WLSH2_k127_604143_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000009048 102.0
WLSH2_k127_604143_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000004551 55.0
WLSH2_k127_604143_4 Transport and Golgi organisation 2 - - - 0.00000006804 55.0
WLSH2_k127_6120737_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 447.0
WLSH2_k127_6120737_1 Glycine cleavage system P-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 356.0
WLSH2_k127_6120737_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
WLSH2_k127_6134865_0 acyl-CoA dehydrogenase K06445 - - 6.52e-321 1003.0
WLSH2_k127_6134865_1 Succinate dehydrogenase fumarate reductase flavoprotein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 365.0
WLSH2_k127_6134865_2 Belongs to the UPF0255 family K11750 GO:0003674,GO:0003824,GO:0005575,GO:0006109,GO:0006629,GO:0008150,GO:0008152,GO:0009894,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0019222,GO:0043470,GO:0044238,GO:0050789,GO:0065007,GO:0071704,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 267.0
WLSH2_k127_6134865_3 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000001177 128.0
WLSH2_k127_6134865_4 4Fe-4S dicluster domain - - - 0.00000000002416 75.0
WLSH2_k127_6134865_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000007867 67.0
WLSH2_k127_6196714_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 2.176e-277 861.0
WLSH2_k127_6196714_1 ABC-2 family transporter protein K13926 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0042623,GO:0043021,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060187,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112 - 4.865e-225 705.0
WLSH2_k127_6196714_10 acetylesterase activity K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000003044 216.0
WLSH2_k127_6196714_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000002367 85.0
WLSH2_k127_6196714_12 YCII-related domain K09780 - - 0.00000000000000003365 87.0
WLSH2_k127_6196714_13 Thioredoxin-like - - - 0.000000000000007626 78.0
WLSH2_k127_6196714_14 Putative cyclase - - - 0.000008758 48.0
WLSH2_k127_6196714_15 peroxiredoxin activity K03564 - 1.11.1.15 0.00001019 53.0
WLSH2_k127_6196714_16 thiol-disulfide isomerase and thioredoxins - - - 0.00055 46.0
WLSH2_k127_6196714_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 568.0
WLSH2_k127_6196714_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 531.0
WLSH2_k127_6196714_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 375.0
WLSH2_k127_6196714_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 328.0
WLSH2_k127_6196714_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 301.0
WLSH2_k127_6196714_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002869 287.0
WLSH2_k127_6196714_8 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002579 272.0
WLSH2_k127_6196714_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000001869 250.0
WLSH2_k127_6219019_0 Tripartite tricarboxylate transporter TctA family - - - 1.137e-215 680.0
WLSH2_k127_6219019_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 599.0
WLSH2_k127_6219019_10 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000188 151.0
WLSH2_k127_6219019_11 - - - - 0.00000000000000000000002757 106.0
WLSH2_k127_6219019_12 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000001769 91.0
WLSH2_k127_6219019_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 317.0
WLSH2_k127_6219019_3 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 293.0
WLSH2_k127_6219019_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001904 282.0
WLSH2_k127_6219019_5 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000006934 240.0
WLSH2_k127_6219019_6 TPM domain - - - 0.00000000000000000000000000000000000000000000000000004911 194.0
WLSH2_k127_6219019_7 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000007359 164.0
WLSH2_k127_6219019_8 - - - - 0.0000000000000000000000000000000000000000007983 159.0
WLSH2_k127_6219019_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000000000001289 163.0
WLSH2_k127_6219741_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 529.0
WLSH2_k127_6219741_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 485.0
WLSH2_k127_6219741_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 298.0
WLSH2_k127_6219741_3 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
WLSH2_k127_6219741_4 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002332 238.0
WLSH2_k127_6219741_5 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000004727 209.0
WLSH2_k127_6219741_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000002507 188.0
WLSH2_k127_6219741_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000002351 173.0
WLSH2_k127_6219741_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000006326 100.0
WLSH2_k127_6219741_9 Belongs to the UPF0276 family K09930 - - 0.00000001195 56.0
WLSH2_k127_6231150_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.132e-284 887.0
WLSH2_k127_6231150_1 7TM diverse intracellular signalling - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
WLSH2_k127_6231150_2 Peptidase family S51 K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007376 267.0
WLSH2_k127_6231150_3 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000003235 143.0
WLSH2_k127_6231150_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000000003961 103.0
WLSH2_k127_6231150_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000002872 103.0
WLSH2_k127_6231150_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000004796 67.0
WLSH2_k127_6231150_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000006922 59.0
WLSH2_k127_6246542_0 2-methylcitrate dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 534.0
WLSH2_k127_6246542_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 532.0
WLSH2_k127_6246542_10 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000006194 226.0
WLSH2_k127_6246542_11 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
WLSH2_k127_6246542_12 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.0000000000000000000000000000000001367 136.0
WLSH2_k127_6246542_13 Class ii aldolase K01628 - 4.1.2.17 0.0000000000000000000000000004394 123.0
WLSH2_k127_6246542_2 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 452.0
WLSH2_k127_6246542_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 444.0
WLSH2_k127_6246542_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 385.0
WLSH2_k127_6246542_5 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
WLSH2_k127_6246542_6 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 321.0
WLSH2_k127_6246542_7 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009181 245.0
WLSH2_k127_6246542_8 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006329 243.0
WLSH2_k127_6246542_9 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001131 238.0
WLSH2_k127_626024_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 9.907e-307 963.0
WLSH2_k127_626024_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.047e-269 845.0
WLSH2_k127_626024_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 290.0
WLSH2_k127_626024_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
WLSH2_k127_626024_12 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000006346 235.0
WLSH2_k127_626024_13 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000001152 227.0
WLSH2_k127_626024_14 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000002776 215.0
WLSH2_k127_626024_15 phosphoribosyltransferase K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
WLSH2_k127_626024_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 523.0
WLSH2_k127_626024_3 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 434.0
WLSH2_k127_626024_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 400.0
WLSH2_k127_626024_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 402.0
WLSH2_k127_626024_6 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 395.0
WLSH2_k127_626024_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 377.0
WLSH2_k127_626024_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 331.0
WLSH2_k127_626024_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
WLSH2_k127_6327927_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 496.0
WLSH2_k127_6327927_1 ThiS family K03154 - - 0.000000000000000000000000006911 111.0
WLSH2_k127_6327927_2 Putative methyltransferase K03439 - 2.1.1.33 0.00000003061 54.0
WLSH2_k127_63591_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 372.0
WLSH2_k127_63591_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
WLSH2_k127_63591_2 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000155 269.0
WLSH2_k127_63591_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000009085 148.0
WLSH2_k127_63591_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000004371 95.0
WLSH2_k127_6441507_0 DNA polymerase K02337 - 2.7.7.7 0.0 1417.0
WLSH2_k127_6441507_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000629 291.0
WLSH2_k127_6441507_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000002764 111.0
WLSH2_k127_6462550_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.819e-280 864.0
WLSH2_k127_6462550_1 Cytochrome c oxidase, subunit K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 393.0
WLSH2_k127_6462550_2 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 334.0
WLSH2_k127_6462550_3 Universal stress protein - - - 0.00000000000000000000000000000132 128.0
WLSH2_k127_6462550_4 iron-sulfur 4fe-4s ferredoxin transmembrane protein - - - 0.000000000000000001892 85.0
WLSH2_k127_6462550_5 Cbb3-type cytochrome oxidase K00407 - - 0.0000000003326 62.0
WLSH2_k127_6479566_0 phosphonate metabolism protein PhnM K06162 - 3.6.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 505.0
WLSH2_k127_6479566_1 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 - 2.7.4.23 0.0000000000000000000000000000000000000000000000000000000001749 210.0
WLSH2_k127_6479566_2 beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000001918 174.0
WLSH2_k127_6577792_0 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 299.0
WLSH2_k127_6577792_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000004475 183.0
WLSH2_k127_6577792_2 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000001618 130.0
WLSH2_k127_6577792_3 Diguanylate cyclase - - - 0.0000000000000000006593 92.0
WLSH2_k127_6671377_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.783e-273 856.0
WLSH2_k127_6671377_1 ABC transporter, ATP-binding protein K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 514.0
WLSH2_k127_6671377_10 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003256 248.0
WLSH2_k127_6671377_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004585 258.0
WLSH2_k127_6671377_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
WLSH2_k127_6671377_13 response to cobalt ion - - - 0.00000000000000000000000000000000000000000000000000004615 191.0
WLSH2_k127_6671377_14 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000003351 185.0
WLSH2_k127_6671377_15 Aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000003881 137.0
WLSH2_k127_6671377_16 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000007821 127.0
WLSH2_k127_6671377_17 Methyltransferase K00567,K10778,K13531 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000007198 97.0
WLSH2_k127_6671377_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 481.0
WLSH2_k127_6671377_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 463.0
WLSH2_k127_6671377_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 464.0
WLSH2_k127_6671377_5 Tyrosine recombinase xerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 412.0
WLSH2_k127_6671377_6 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 401.0
WLSH2_k127_6671377_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 303.0
WLSH2_k127_6671377_8 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 295.0
WLSH2_k127_6671377_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002344 263.0
WLSH2_k127_668082_0 Molecular chaperone. Has ATPase activity K04079 - - 2.688e-299 930.0
WLSH2_k127_668082_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 561.0
WLSH2_k127_668082_10 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000003269 225.0
WLSH2_k127_668082_11 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000002582 220.0
WLSH2_k127_668082_12 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000001135 212.0
WLSH2_k127_668082_13 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000004357 200.0
WLSH2_k127_668082_14 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000005342 195.0
WLSH2_k127_668082_15 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000001042 194.0
WLSH2_k127_668082_2 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
WLSH2_k127_668082_3 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 456.0
WLSH2_k127_668082_4 PFAM fumarylacetoacetate (FAA) hydrolase K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 380.0
WLSH2_k127_668082_5 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 337.0
WLSH2_k127_668082_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 329.0
WLSH2_k127_668082_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 320.0
WLSH2_k127_668082_8 membrane protein, TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 287.0
WLSH2_k127_668082_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
WLSH2_k127_675996_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
WLSH2_k127_675996_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
WLSH2_k127_675996_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000273 211.0
WLSH2_k127_6862782_0 Malic enzyme K00029 - 1.1.1.40 0.0 1039.0
WLSH2_k127_6862782_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.396e-213 670.0
WLSH2_k127_6862782_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 367.0
WLSH2_k127_6862782_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009908 290.0
WLSH2_k127_6862782_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000003611 198.0
WLSH2_k127_6862782_6 PFAM Response regulator receiver domain, Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000003294 175.0
WLSH2_k127_6862782_7 Protein of unknown function (DUF3225) - - - 0.00000000000000000000000000000000000000000000001835 173.0
WLSH2_k127_6862782_8 - - - - 0.0000000000000000000000000003161 120.0
WLSH2_k127_6908258_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 488.0
WLSH2_k127_6908258_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
WLSH2_k127_6908258_2 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000006886 156.0
WLSH2_k127_6908258_3 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000001572 109.0
WLSH2_k127_6908258_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000002984 102.0
WLSH2_k127_6909349_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1341.0
WLSH2_k127_6909349_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.909e-221 691.0
WLSH2_k127_6909349_10 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 358.0
WLSH2_k127_6909349_11 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
WLSH2_k127_6909349_12 POTRA domain, FtsQ-type - - - 0.00000000000000000000000000000000000000000000000000004936 196.0
WLSH2_k127_6909349_13 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000006007 184.0
WLSH2_k127_6909349_14 Protein conserved in bacteria - - - 0.000000002539 65.0
WLSH2_k127_6909349_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.741e-211 666.0
WLSH2_k127_6909349_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 564.0
WLSH2_k127_6909349_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 558.0
WLSH2_k127_6909349_5 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 546.0
WLSH2_k127_6909349_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 478.0
WLSH2_k127_6909349_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 445.0
WLSH2_k127_6909349_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 411.0
WLSH2_k127_6909349_9 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 387.0
WLSH2_k127_6959425_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.216e-253 792.0
WLSH2_k127_6959425_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000001236 216.0
WLSH2_k127_6959425_2 RND efflux system, outer membrane lipoprotein K18139,K18903 - - 0.0000000000000000000000000000000000000000000001758 173.0
WLSH2_k127_6966912_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1019.0
WLSH2_k127_6966912_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.283e-241 767.0
WLSH2_k127_6966912_2 Circularly permuted ATP-grasp type 2 - - - 7.39e-225 706.0
WLSH2_k127_6966912_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
WLSH2_k127_6966912_4 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 349.0
WLSH2_k127_6966912_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004849 260.0
WLSH2_k127_6966912_6 PFAM 20S proteasome, A and B subunits K07395 - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
WLSH2_k127_6966912_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000006146 185.0
WLSH2_k127_6966912_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000206 97.0
WLSH2_k127_6966912_9 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000005934 90.0
WLSH2_k127_702245_0 PFAM Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 547.0
WLSH2_k127_702245_1 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 512.0
WLSH2_k127_702245_10 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
WLSH2_k127_702245_11 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000001571 227.0
WLSH2_k127_702245_12 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000004675 213.0
WLSH2_k127_702245_13 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000000001008 192.0
WLSH2_k127_702245_14 Ferredoxin - - - 0.0000000000000000000000000000000000000000000008542 167.0
WLSH2_k127_702245_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000003285 147.0
WLSH2_k127_702245_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000004162 96.0
WLSH2_k127_702245_17 Protein of unknown function (DUF2909) - - - 0.0000000000001725 72.0
WLSH2_k127_702245_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 434.0
WLSH2_k127_702245_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 428.0
WLSH2_k127_702245_4 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 410.0
WLSH2_k127_702245_5 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 388.0
WLSH2_k127_702245_6 Cytochrome oxidase assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 365.0
WLSH2_k127_702245_7 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 303.0
WLSH2_k127_702245_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 298.0
WLSH2_k127_702245_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 291.0
WLSH2_k127_7060849_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 6.727e-245 761.0
WLSH2_k127_7060849_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.991e-198 636.0
WLSH2_k127_7060849_10 Thioredoxin-like - - - 0.0000000000000000000000000000000000001729 148.0
WLSH2_k127_7060849_11 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000004554 143.0
WLSH2_k127_7060849_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 406.0
WLSH2_k127_7060849_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 362.0
WLSH2_k127_7060849_4 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 323.0
WLSH2_k127_7060849_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000001219 207.0
WLSH2_k127_7060849_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000001726 197.0
WLSH2_k127_7060849_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000002428 193.0
WLSH2_k127_7060849_8 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000001426 188.0
WLSH2_k127_7060849_9 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000000002518 151.0
WLSH2_k127_7089763_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 472.0
WLSH2_k127_7089763_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 423.0
WLSH2_k127_7089763_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 418.0
WLSH2_k127_7089763_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
WLSH2_k127_7089763_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000513 204.0
WLSH2_k127_7089763_5 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.0000000000000000000000000000000003524 135.0
WLSH2_k127_7089763_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000001619 118.0
WLSH2_k127_7089763_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000007279 106.0
WLSH2_k127_7089763_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000002814 85.0
WLSH2_k127_7089763_9 - - - - 0.0000000000002477 76.0
WLSH2_k127_7111536_0 von Willebrand factor (vWF) type A domain K02448 - - 6.672e-196 634.0
WLSH2_k127_7111536_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 404.0
WLSH2_k127_7111536_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006248 261.0
WLSH2_k127_7111536_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000004848 88.0
WLSH2_k127_7156733_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 543.0
WLSH2_k127_7156733_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 298.0
WLSH2_k127_7156733_2 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000007702 216.0
WLSH2_k127_7156733_3 AzlC protein - - - 0.000000000000000000000000001056 119.0
WLSH2_k127_7156733_4 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000003025 96.0
WLSH2_k127_7196179_0 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 591.0
WLSH2_k127_7196179_1 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 455.0
WLSH2_k127_7196179_2 COG0277 FAD FMN-containing dehydrogenases K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 397.0
WLSH2_k127_7196179_3 COG2931 RTX toxins and related Ca2 -binding - - - 0.000000000000000000000182 106.0
WLSH2_k127_7196997_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 448.0
WLSH2_k127_7196997_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
WLSH2_k127_7196997_2 - K01992 - - 0.00000000000000000000000000000000000000000000008902 178.0
WLSH2_k127_7196997_3 general secretion pathway protein - - - 0.000000000000000000000000000000000000000000003062 171.0
WLSH2_k127_7196997_4 - - - - 0.00000000000000000000000000000000006608 145.0
WLSH2_k127_7196997_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000004545 139.0
WLSH2_k127_7196997_6 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 0.0000000533 54.0
WLSH2_k127_7196997_7 tigrfam pep-cterm - - - 0.0001533 51.0
WLSH2_k127_7201923_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.399e-289 893.0
WLSH2_k127_7201923_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 485.0
WLSH2_k127_7201923_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
WLSH2_k127_7201923_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000007014 241.0
WLSH2_k127_7201923_4 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 236.0
WLSH2_k127_7201923_5 membrane - - - 0.0000000000000002659 85.0
WLSH2_k127_7201923_6 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000001454 79.0
WLSH2_k127_7201923_7 Protein of unknown function (DUF2970) - - - 0.0006429 45.0
WLSH2_k127_7244860_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.986e-261 815.0
WLSH2_k127_7244860_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 325.0
WLSH2_k127_7244860_2 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000007079 57.0
WLSH2_k127_7473872_0 FAD linked oxidase domain protein K06911 - - 0.0 1261.0
WLSH2_k127_7473872_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K03852 - 2.3.3.15 2.031e-264 828.0
WLSH2_k127_7473872_2 argininosuccinate lyase K01755 - 4.3.2.1 1.066e-226 709.0
WLSH2_k127_7473872_3 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 387.0
WLSH2_k127_7473872_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
WLSH2_k127_7473872_5 Transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 345.0
WLSH2_k127_7473872_6 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
WLSH2_k127_7473872_7 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 289.0
WLSH2_k127_7473872_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000002383 164.0
WLSH2_k127_7473872_9 Thioredoxin-like - - - 0.0000000000000000000000006028 114.0
WLSH2_k127_7485240_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 2.236e-216 682.0
WLSH2_k127_7485240_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 585.0
WLSH2_k127_7485240_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 502.0
WLSH2_k127_7485240_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 474.0
WLSH2_k127_7485240_4 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 322.0
WLSH2_k127_7485240_5 Sigma E regulatory protein, MucB RseB K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 258.0
WLSH2_k127_7485240_6 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.0000000000000000000000000000009947 129.0
WLSH2_k127_7507255_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 364.0
WLSH2_k127_7507255_1 SMP-30 Gluconolaconase LRE domain protein K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 352.0
WLSH2_k127_7507255_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 343.0
WLSH2_k127_7507255_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 291.0
WLSH2_k127_7507255_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002339 279.0
WLSH2_k127_7507255_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003948 261.0
WLSH2_k127_7606946_0 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 504.0
WLSH2_k127_7606946_2 COG5126 Ca2 -binding protein (EF-Hand superfamily - - - 0.00000000000000000000002633 106.0
WLSH2_k127_7606946_3 - - - - 0.0000000000000000002293 91.0
WLSH2_k127_7606946_4 Putative DNA-binding domain K09929 - - 0.0000000006747 63.0
WLSH2_k127_7627931_0 PFAM Glycoside hydrolase 15-related - - - 5.506e-304 936.0
WLSH2_k127_7627931_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 557.0
WLSH2_k127_7627931_2 PFAM ATPase associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 414.0
WLSH2_k127_7627931_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 374.0
WLSH2_k127_7627931_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000002751 244.0
WLSH2_k127_7627931_5 - - - - 0.00000000000000000000000000003093 122.0
WLSH2_k127_7627931_6 - - - - 0.0000000000000000000000000002589 117.0
WLSH2_k127_7627931_7 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000006686 118.0
WLSH2_k127_7740044_0 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 505.0
WLSH2_k127_7740044_1 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
WLSH2_k127_7740044_2 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000003511 128.0
WLSH2_k127_7740044_3 COG5126 Ca2 -binding protein (EF-Hand superfamily - - - 0.00000000000000000000002607 104.0
WLSH2_k127_7740044_4 - - - - 0.0000000000159 68.0
WLSH2_k127_7794847_0 Cytochrome c bacterial - - - 1.832e-247 773.0
WLSH2_k127_7794847_1 - K07112 - - 8.5e-227 707.0
WLSH2_k127_7794847_10 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000007952 100.0
WLSH2_k127_7794847_11 - - - - 0.000000000000000000001925 96.0
WLSH2_k127_7794847_12 Helix-hairpin-helix motif - - - 0.0000000000000000003326 90.0
WLSH2_k127_7794847_13 Protein of unknown function (DUF1499) - - - 0.00000000000132 76.0
WLSH2_k127_7794847_14 - - - - 0.00000000000139 76.0
WLSH2_k127_7794847_15 OsmC-like protein - - - 0.000000001171 63.0
WLSH2_k127_7794847_2 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 478.0
WLSH2_k127_7794847_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 380.0
WLSH2_k127_7794847_4 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 352.0
WLSH2_k127_7794847_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 308.0
WLSH2_k127_7794847_6 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 287.0
WLSH2_k127_7794847_7 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000006379 201.0
WLSH2_k127_7794847_9 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000003491 132.0
WLSH2_k127_7870647_0 mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 355.0
WLSH2_k127_7870647_1 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 323.0
WLSH2_k127_7870647_2 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 262.0
WLSH2_k127_7870647_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
WLSH2_k127_7870647_4 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000008798 230.0
WLSH2_k127_7907096_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.804e-215 676.0
WLSH2_k127_7907096_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 587.0
WLSH2_k127_7907096_2 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 336.0
WLSH2_k127_7907096_3 Nitroreductase family K19286 - 1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
WLSH2_k127_7907096_4 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
WLSH2_k127_7907096_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000003792 241.0
WLSH2_k127_7907096_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000006871 158.0
WLSH2_k127_7907096_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000001777 122.0
WLSH2_k127_7933495_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 434.0
WLSH2_k127_7933495_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 366.0
WLSH2_k127_7933495_2 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 279.0
WLSH2_k127_7933495_3 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000004171 115.0
WLSH2_k127_7933495_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000005271 83.0
WLSH2_k127_7936516_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 575.0
WLSH2_k127_7936516_1 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006877 278.0
WLSH2_k127_7936516_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000001066 224.0
WLSH2_k127_7936516_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000001753 187.0
WLSH2_k127_7936516_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000001851 150.0
WLSH2_k127_7942573_0 Sulfate transporter antisigma-factor antagonist STAS - - - 2.41e-242 771.0
WLSH2_k127_7942573_1 STAS domain K03321 - - 7.365e-206 657.0
WLSH2_k127_7942573_10 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000001333 56.0
WLSH2_k127_7942573_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 317.0
WLSH2_k127_7942573_3 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
WLSH2_k127_7942573_4 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000004963 247.0
WLSH2_k127_7942573_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000001052 137.0
WLSH2_k127_7942573_6 Cytochrome c - - - 0.0000000000000000000000000000004057 130.0
WLSH2_k127_7942573_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000008978 122.0
WLSH2_k127_7942573_8 Universal stress protein - - - 0.00000000000000000000000000003327 127.0
WLSH2_k127_7942573_9 Bacterial SH3 domain - - - 0.00000000000000239 85.0
WLSH2_k127_794902_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 3.893e-219 691.0
WLSH2_k127_794902_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 545.0
WLSH2_k127_794902_10 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001777 295.0
WLSH2_k127_794902_11 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
WLSH2_k127_794902_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002647 272.0
WLSH2_k127_794902_13 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003159 262.0
WLSH2_k127_794902_14 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000000000006692 209.0
WLSH2_k127_794902_15 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000001603 193.0
WLSH2_k127_794902_16 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000002623 166.0
WLSH2_k127_794902_17 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000008083 166.0
WLSH2_k127_794902_18 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000004528 134.0
WLSH2_k127_794902_19 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000004215 129.0
WLSH2_k127_794902_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 506.0
WLSH2_k127_794902_20 Chalcone isomerase-like - - - 0.000000000000000009938 90.0
WLSH2_k127_794902_21 protein conserved in bacteria - - - 0.000000000001315 69.0
WLSH2_k127_794902_22 (Lipo)protein K07121 - - 0.00000000006249 70.0
WLSH2_k127_794902_23 - - - - 0.0000000003557 68.0
WLSH2_k127_794902_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 437.0
WLSH2_k127_794902_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 369.0
WLSH2_k127_794902_5 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
WLSH2_k127_794902_6 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 335.0
WLSH2_k127_794902_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
WLSH2_k127_794902_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 306.0
WLSH2_k127_794902_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 298.0
WLSH2_k127_7976699_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
WLSH2_k127_7976699_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000008736 168.0
WLSH2_k127_7976699_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000039 81.0
WLSH2_k127_7980607_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 364.0
WLSH2_k127_7980607_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 297.0
WLSH2_k127_7980607_2 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
WLSH2_k127_7980607_3 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000004118 180.0
WLSH2_k127_7980607_4 CoA-transferase family III - - - 0.00000000000000000000000000000000001605 137.0
WLSH2_k127_8020528_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 584.0
WLSH2_k127_8020528_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 469.0
WLSH2_k127_8020528_2 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 392.0
WLSH2_k127_8020528_3 methyl-accepting chemotaxis protein K07315 - 3.1.3.3 0.0000000000000000000000000001432 126.0
WLSH2_k127_8020528_4 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000009332 102.0
WLSH2_k127_8030246_0 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 314.0
WLSH2_k127_8030246_1 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000003085 131.0
WLSH2_k127_8030246_2 cytochrome C K08738 - - 0.000001602 51.0
WLSH2_k127_8031913_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 602.0
WLSH2_k127_8031913_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 581.0
WLSH2_k127_8031913_10 - - - - 0.0000000000000000000000001128 115.0
WLSH2_k127_8031913_11 - - - - 0.0000000000000000005972 88.0
WLSH2_k127_8031913_12 protein conserved in bacteria - - - 0.00000003094 61.0
WLSH2_k127_8031913_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 541.0
WLSH2_k127_8031913_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 397.0
WLSH2_k127_8031913_4 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 380.0
WLSH2_k127_8031913_5 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 354.0
WLSH2_k127_8031913_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 316.0
WLSH2_k127_8031913_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001119 274.0
WLSH2_k127_8031913_8 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001794 236.0
WLSH2_k127_8031913_9 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001367 235.0
WLSH2_k127_8178572_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 458.0
WLSH2_k127_8178572_1 Predicted methyltransferase regulatory domain - - - 0.0000000000003874 78.0
WLSH2_k127_8334740_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 471.0
WLSH2_k127_8334740_1 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 365.0
WLSH2_k127_8334740_2 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000003404 199.0
WLSH2_k127_8334740_3 Histidine triad (HIT) - - - 0.00000000000000000000000000000000000000000000513 166.0
WLSH2_k127_8334740_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000005952 113.0
WLSH2_k127_8352169_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 475.0
WLSH2_k127_8352169_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 360.0
WLSH2_k127_8352169_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 322.0
WLSH2_k127_8352169_3 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000651 262.0
WLSH2_k127_8352169_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000006942 254.0
WLSH2_k127_8352169_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000001198 169.0
WLSH2_k127_8352169_6 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000000000002953 125.0
WLSH2_k127_8352169_7 glycosyl transferase family - - - 0.0000000000000000000000001659 110.0
WLSH2_k127_838921_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.027e-249 781.0
WLSH2_k127_838921_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 439.0
WLSH2_k127_838921_2 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 308.0
WLSH2_k127_838921_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000001481 142.0
WLSH2_k127_838921_4 universal stress protein - - - 0.000000000000000000000000000002417 125.0
WLSH2_k127_8422900_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5.123e-241 753.0
WLSH2_k127_8422900_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.921e-222 709.0
WLSH2_k127_8422900_10 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000000005339 155.0
WLSH2_k127_8422900_11 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000008049 148.0
WLSH2_k127_8422900_12 Protein of unknown function (DUF502) - - - 0.00000004023 57.0
WLSH2_k127_8422900_2 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 485.0
WLSH2_k127_8422900_3 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
WLSH2_k127_8422900_4 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 334.0
WLSH2_k127_8422900_5 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
WLSH2_k127_8422900_6 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000000000000000000004669 229.0
WLSH2_k127_8422900_7 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000001408 219.0
WLSH2_k127_8422900_8 - - - - 0.000000000000000000000000000000000000000000000000699 179.0
WLSH2_k127_8422900_9 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000000000000000001424 164.0
WLSH2_k127_8455887_0 Bacterial regulatory protein, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 509.0
WLSH2_k127_8455887_1 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
WLSH2_k127_8455887_2 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 294.0
WLSH2_k127_8455887_3 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000009958 132.0
WLSH2_k127_856875_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 7.331e-260 804.0
WLSH2_k127_856875_1 glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 591.0
WLSH2_k127_856875_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 520.0
WLSH2_k127_856875_3 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 510.0
WLSH2_k127_856875_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000000000000000001234 196.0
WLSH2_k127_856875_5 - - - - 0.000000000000000000000000000000000000000000000000000003234 198.0
WLSH2_k127_856875_6 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.0000000000000000000000002516 106.0
WLSH2_k127_856875_7 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000002295 100.0
WLSH2_k127_856875_8 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000004952 88.0
WLSH2_k127_8572074_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 384.0
WLSH2_k127_8572074_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 355.0
WLSH2_k127_8572074_2 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000319 262.0
WLSH2_k127_8588878_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 450.0
WLSH2_k127_8588878_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 451.0
WLSH2_k127_8588878_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
WLSH2_k127_8588878_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 336.0
WLSH2_k127_8588878_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004941 246.0
WLSH2_k127_8588878_5 - K09004 - - 0.000000000000000000000003867 110.0
WLSH2_k127_8588878_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000006737 104.0
WLSH2_k127_8588878_7 - - - - 0.0000000003389 69.0
WLSH2_k127_863782_0 FAD linked oxidase domain protein - - - 0.0 1856.0
WLSH2_k127_863782_1 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 404.0
WLSH2_k127_863782_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001614 250.0
WLSH2_k127_863782_3 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000002438 237.0
WLSH2_k127_863782_4 membrane - - - 0.00000000000000000000000000000000000000000000000008556 181.0
WLSH2_k127_863782_5 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000002693 126.0
WLSH2_k127_863782_6 Histidine triad domain protein - - - 0.000000000000000315 88.0
WLSH2_k127_863782_7 - - - - 0.000000000008375 78.0
WLSH2_k127_8742393_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 9.272e-202 635.0
WLSH2_k127_8742393_1 PFAM methyltransferase - - - 0.0000000000000005283 78.0
WLSH2_k127_8761789_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1248.0
WLSH2_k127_8761789_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1077.0
WLSH2_k127_8761789_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002593 289.0
WLSH2_k127_8761789_11 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 273.0
WLSH2_k127_8761789_12 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009881 271.0
WLSH2_k127_8761789_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001734 246.0
WLSH2_k127_8761789_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
WLSH2_k127_8761789_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
WLSH2_k127_8761789_16 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000001238 194.0
WLSH2_k127_8761789_17 Oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000000000000006307 186.0
WLSH2_k127_8761789_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000001099 151.0
WLSH2_k127_8761789_19 Ribosomal_S15 K02956 - - 0.0000000000000000000000000000000000002125 141.0
WLSH2_k127_8761789_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.012e-318 993.0
WLSH2_k127_8761789_20 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000001019 100.0
WLSH2_k127_8761789_21 - - - - 0.00000000000000000006785 94.0
WLSH2_k127_8761789_23 Sulfurtransferase - - - 0.00000000001044 67.0
WLSH2_k127_8761789_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.347e-236 740.0
WLSH2_k127_8761789_4 Participates in both transcription termination and antitermination K02600 - - 1.409e-229 722.0
WLSH2_k127_8761789_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.837e-220 686.0
WLSH2_k127_8761789_6 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 516.0
WLSH2_k127_8761789_7 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 329.0
WLSH2_k127_8761789_8 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 331.0
WLSH2_k127_8761789_9 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 312.0
WLSH2_k127_8763848_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2449.0
WLSH2_k127_8763848_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 349.0
WLSH2_k127_8763848_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001013 282.0
WLSH2_k127_8763848_3 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000007683 218.0
WLSH2_k127_8763848_4 major facilitator superfamily - - - 0.0000000000000000000000001369 118.0
WLSH2_k127_8763848_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000001344 69.0
WLSH2_k127_8763848_6 response to heat K03668,K09914 - - 0.0005153 50.0
WLSH2_k127_8773120_0 GTP-binding protein K06207 - - 4.435e-309 956.0
WLSH2_k127_8773120_1 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 475.0
WLSH2_k127_8773120_2 surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 459.0
WLSH2_k127_8773120_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 451.0
WLSH2_k127_8773120_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 311.0
WLSH2_k127_8773120_5 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000006238 179.0
WLSH2_k127_8781682_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.864e-244 764.0
WLSH2_k127_8781682_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 1.61e-200 644.0
WLSH2_k127_8781682_10 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 456.0
WLSH2_k127_8781682_11 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 351.0
WLSH2_k127_8781682_12 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 342.0
WLSH2_k127_8781682_13 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 311.0
WLSH2_k127_8781682_14 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002208 274.0
WLSH2_k127_8781682_15 - - - - 0.0000000000000000000000000004164 119.0
WLSH2_k127_8781682_16 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000001126 109.0
WLSH2_k127_8781682_17 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000004307 77.0
WLSH2_k127_8781682_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.548e-197 641.0
WLSH2_k127_8781682_3 Belongs to the GARS family K01945 - 6.3.4.13 3.113e-196 619.0
WLSH2_k127_8781682_4 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 9.215e-194 613.0
WLSH2_k127_8781682_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 560.0
WLSH2_k127_8781682_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 513.0
WLSH2_k127_8781682_7 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 494.0
WLSH2_k127_8781682_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 474.0
WLSH2_k127_8781682_9 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 443.0
WLSH2_k127_8860523_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 588.0
WLSH2_k127_8860523_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 316.0
WLSH2_k127_8860523_2 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000004057 148.0
WLSH2_k127_891958_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.99e-227 709.0
WLSH2_k127_891958_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 527.0
WLSH2_k127_891958_2 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 383.0
WLSH2_k127_891958_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 358.0
WLSH2_k127_891958_4 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
WLSH2_k127_891958_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 326.0
WLSH2_k127_891958_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000003315 176.0
WLSH2_k127_891958_7 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000008748 121.0
WLSH2_k127_891958_8 - - - - 0.000004111 50.0
WLSH2_k127_9066054_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.371e-227 711.0
WLSH2_k127_9066054_1 von Willebrand factor (vWF) type A domain - - - 3.232e-217 695.0
WLSH2_k127_9066054_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
WLSH2_k127_9066054_11 acyl-CoA dehydrogenase K20035 - - 0.00000000000000000000000000000000000000000000008077 173.0
WLSH2_k127_9066054_12 - - - - 0.000000000000000000000000009232 126.0
WLSH2_k127_9066054_13 - - - - 0.000000000000000000000309 100.0
WLSH2_k127_9066054_2 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 572.0
WLSH2_k127_9066054_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 432.0
WLSH2_k127_9066054_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 416.0
WLSH2_k127_9066054_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 427.0
WLSH2_k127_9066054_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 392.0
WLSH2_k127_9066054_7 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 373.0
WLSH2_k127_9066054_8 GMP synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009228 261.0
WLSH2_k127_9066054_9 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005239 256.0
WLSH2_k127_9079952_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 421.0
WLSH2_k127_9079952_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 331.0
WLSH2_k127_9079952_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 329.0
WLSH2_k127_9079952_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000001392 146.0
WLSH2_k127_9105398_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 611.0
WLSH2_k127_9105398_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 413.0
WLSH2_k127_9105398_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 307.0
WLSH2_k127_9105398_3 Lysin motif K06194 - - 0.0000000000000000000005854 95.0
WLSH2_k127_9131400_0 polyphosphate kinase - - - 3.082e-220 693.0
WLSH2_k127_9131400_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 589.0
WLSH2_k127_9131400_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 437.0
WLSH2_k127_9131400_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 311.0
WLSH2_k127_9131400_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 311.0
WLSH2_k127_9131400_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000001221 183.0
WLSH2_k127_9131400_6 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000000000000003163 172.0
WLSH2_k127_9131400_7 CHAD - - - 0.00000000000000007252 85.0
WLSH2_k127_9151272_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846 - 4.4.1.24 1.266e-215 674.0
WLSH2_k127_9151272_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 347.0
WLSH2_k127_9151272_2 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000147 256.0
WLSH2_k127_9151272_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000003685 196.0
WLSH2_k127_9151272_4 SAF K16845 - 4.4.1.24 0.0000000000000000000000000000000000007617 141.0
WLSH2_k127_9151272_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000007963 83.0
WLSH2_k127_9165017_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 354.0
WLSH2_k127_9165017_1 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
WLSH2_k127_9165017_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
WLSH2_k127_9165017_3 LemA family - - - 0.0000000000000000000000000000000000000000000000000000007536 194.0
WLSH2_k127_9165017_4 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000001936 174.0
WLSH2_k127_9221529_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 7.418e-263 824.0
WLSH2_k127_9221529_1 Fumarate reductase flavoprotein C-term - - - 7.289e-256 801.0
WLSH2_k127_9221529_10 Fumarate reductase subunit D - - - 0.00000000000000000000001055 105.0
WLSH2_k127_9221529_2 COG1230 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 401.0
WLSH2_k127_9221529_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 338.0
WLSH2_k127_9221529_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 319.0
WLSH2_k127_9221529_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 316.0
WLSH2_k127_9221529_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004259 264.0
WLSH2_k127_9221529_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005385 257.0
WLSH2_k127_9221529_8 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000009122 158.0
WLSH2_k127_9221529_9 Fumarate reductase subunit C - - - 0.0000000000000000000000000000008646 130.0
WLSH2_k127_9224632_0 Luciferase-like monooxygenase K00494 - 1.14.14.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 441.0
WLSH2_k127_9224632_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 409.0
WLSH2_k127_9224632_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 390.0
WLSH2_k127_9224632_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000006194 204.0
WLSH2_k127_9224632_4 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000001507 174.0
WLSH2_k127_938039_0 of murein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 311.0
WLSH2_k127_938039_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003372 287.0
WLSH2_k127_938039_10 Bacterial protein of unknown function (DUF883) - - - 0.0000000001157 63.0
WLSH2_k127_938039_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001859 246.0
WLSH2_k127_938039_3 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001205 243.0
WLSH2_k127_938039_4 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000002318 197.0
WLSH2_k127_938039_5 effector of murein hydrolase LrgA K06518 - - 0.000000000000000000000000000000009957 130.0
WLSH2_k127_938039_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000008392 127.0
WLSH2_k127_938039_7 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000001289 105.0
WLSH2_k127_938039_8 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.0000000000000000341 93.0
WLSH2_k127_938039_9 - - - - 0.0000000000003546 73.0
WLSH2_k127_9458393_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.074e-229 720.0
WLSH2_k127_9458393_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 567.0
WLSH2_k127_9458393_10 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000001176 208.0
WLSH2_k127_9458393_11 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000004776 199.0
WLSH2_k127_9458393_12 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000005552 172.0
WLSH2_k127_9458393_13 protein conserved in bacteria K11719 - - 0.00000000000000000000000000000000000000000002538 168.0
WLSH2_k127_9458393_14 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000464 136.0
WLSH2_k127_9458393_15 protein involved in propionate catabolism - - - 0.000000000005334 73.0
WLSH2_k127_9458393_2 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 430.0
WLSH2_k127_9458393_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 386.0
WLSH2_k127_9458393_4 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 377.0
WLSH2_k127_9458393_5 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
WLSH2_k127_9458393_6 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000000000001131 222.0
WLSH2_k127_9458393_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000000000000003191 215.0
WLSH2_k127_9458393_8 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000001064 207.0
WLSH2_k127_9458393_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000000000005335 209.0
WLSH2_k127_9475188_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15576 - - 3.314e-235 737.0
WLSH2_k127_9475188_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.67e-225 708.0
WLSH2_k127_9475188_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000002224 182.0
WLSH2_k127_9475188_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.086e-204 645.0
WLSH2_k127_9475188_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.032e-200 633.0
WLSH2_k127_9475188_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 559.0
WLSH2_k127_9475188_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 510.0
WLSH2_k127_9475188_6 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 417.0
WLSH2_k127_9475188_7 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 415.0
WLSH2_k127_9475188_8 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000001463 229.0
WLSH2_k127_9475188_9 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001383 177.0
WLSH2_k127_9490098_0 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 394.0
WLSH2_k127_9490098_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 292.0
WLSH2_k127_9490098_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000241 277.0
WLSH2_k127_9490098_3 ornithine cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000181 246.0
WLSH2_k127_9490098_4 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000002852 209.0
WLSH2_k127_9490098_5 membrane - - - 0.000000000000000000000000000000000000000000000000000001292 201.0
WLSH2_k127_9490098_6 pyridoxamine 5-phosphate - - - 0.000000000000000000005314 100.0
WLSH2_k127_9510738_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.028e-260 808.0
WLSH2_k127_9510738_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 512.0
WLSH2_k127_9510738_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 507.0
WLSH2_k127_9510738_3 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 430.0
WLSH2_k127_9510738_4 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000003061 191.0
WLSH2_k127_9510738_5 Universal stress protein family - - - 0.000000000000000000000000001465 117.0
WLSH2_k127_9524347_0 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 347.0
WLSH2_k127_9524347_1 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 328.0
WLSH2_k127_9524347_2 Amidohydrolase family - - - 0.00000000000000000000000000000004621 128.0
WLSH2_k127_9533732_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 521.0
WLSH2_k127_9533732_1 PFAM CBS domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 400.0
WLSH2_k127_9533732_2 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
WLSH2_k127_9533732_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000001429 154.0
WLSH2_k127_95684_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 451.0
WLSH2_k127_95684_1 Acyl-CoA synthetase (NDP forming) K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 371.0
WLSH2_k127_95684_2 ThiS family K03154 - - 0.00000000000000000004505 91.0
WLSH2_k127_9587747_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.977e-251 781.0
WLSH2_k127_9587747_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.916e-209 654.0
WLSH2_k127_9587747_10 PFAM Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000001468 158.0
WLSH2_k127_9587747_11 Sporulation related domain K03749 - - 0.00000000000000000000000001229 117.0
WLSH2_k127_9587747_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 578.0
WLSH2_k127_9587747_3 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 469.0
WLSH2_k127_9587747_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 348.0
WLSH2_k127_9587747_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001252 278.0
WLSH2_k127_9587747_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001131 271.0
WLSH2_k127_9587747_7 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
WLSH2_k127_9587747_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000002314 243.0
WLSH2_k127_9587747_9 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000001448 201.0
WLSH2_k127_9592432_0 4Fe-4S dicluster domain - - - 3.697e-223 711.0
WLSH2_k127_9592432_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 469.0
WLSH2_k127_9592432_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 392.0
WLSH2_k127_9592432_3 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 297.0
WLSH2_k127_9592432_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 283.0
WLSH2_k127_9592432_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005847 256.0
WLSH2_k127_9592432_6 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000002049 154.0
WLSH2_k127_9592432_7 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000003428 153.0
WLSH2_k127_9592432_8 Protein of unknown function (DUF3306) - - - 0.00000000000000000000000008267 116.0
WLSH2_k127_9592432_9 - - - - 0.0003638 46.0
WLSH2_k127_9595997_0 ABC transporter transmembrane region K06147 - - 6.919e-215 680.0
WLSH2_k127_9595997_1 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 351.0
WLSH2_k127_9595997_2 Beta-lactamase enzyme family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 299.0
WLSH2_k127_9595997_3 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 287.0
WLSH2_k127_9595997_4 Methyl-transferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005943 280.0
WLSH2_k127_9595997_5 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 0.000000000000001825 77.0
WLSH2_k127_9595997_6 PFAM 17 kDa surface antigen - - - 0.0000007169 56.0
WLSH2_k127_9612682_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.968e-210 661.0
WLSH2_k127_9612682_1 Glutathione S-transferase, N-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 352.0
WLSH2_k127_9612682_2 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
WLSH2_k127_9612682_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
WLSH2_k127_9612682_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006512 257.0
WLSH2_k127_9612682_5 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000004555 156.0
WLSH2_k127_9612682_6 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000001512 128.0
WLSH2_k127_9612682_7 Amidohydrolase K07045 - - 0.000003697 53.0
WLSH2_k127_9622767_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 595.0
WLSH2_k127_9622767_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001633 283.0
WLSH2_k127_9622767_2 DsrC like protein - - - 0.00000000000000000000000000000000000000000000000000000002028 197.0
WLSH2_k127_9705880_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 417.0
WLSH2_k127_9705880_1 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 388.0
WLSH2_k127_9705880_10 Transcriptional regulator - - - 0.000000000000000000000002571 108.0
WLSH2_k127_9705880_11 Glycine zipper 2TM domain K04062 - - 0.00000000000000000000000949 102.0
WLSH2_k127_9705880_12 - - - - 0.0000000000000000000001784 102.0
WLSH2_k127_9705880_13 - - - - 0.000000000000000007963 83.0
WLSH2_k127_9705880_14 ABC transporter substrate-binding protein K02020,K22003 - 5.3.3.7 0.0000000000000005473 85.0
WLSH2_k127_9705880_15 Protein of unknown function (DUF3096) - - - 0.00000000000004776 72.0
WLSH2_k127_9705880_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 376.0
WLSH2_k127_9705880_3 Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 346.0
WLSH2_k127_9705880_4 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008668 277.0
WLSH2_k127_9705880_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002048 255.0
WLSH2_k127_9705880_6 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000002067 220.0
WLSH2_k127_9705880_7 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000001268 176.0
WLSH2_k127_9705880_8 tungstate binding K02020 - - 0.000000000000000000000000000000000000000000002212 175.0
WLSH2_k127_9705880_9 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000005383 141.0
WLSH2_k127_9716945_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 9.662e-306 946.0
WLSH2_k127_9716945_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 524.0
WLSH2_k127_9716945_2 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
WLSH2_k127_9716945_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 321.0
WLSH2_k127_9716945_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 293.0
WLSH2_k127_9716945_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000009026 166.0
WLSH2_k127_9716945_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000005295 130.0
WLSH2_k127_9716945_7 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000001092 77.0
WLSH2_k127_9974790_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 519.0
WLSH2_k127_9974790_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 441.0
WLSH2_k127_9988386_0 Belongs to the IlvD Edd family - - - 6.155e-287 889.0
WLSH2_k127_9988386_1 O-acetylhomoserine K01740 - 2.5.1.49 2.549e-238 741.0
WLSH2_k127_9988386_2 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 465.0
WLSH2_k127_9988386_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 398.0
WLSH2_k127_9988386_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 380.0
WLSH2_k127_9988386_5 Amino Acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 347.0
WLSH2_k127_9988386_6 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000007406 155.0
WLSH2_k127_9988386_7 SapC - - - 0.00000000000000000000000000000000000201 151.0
WLSH2_k127_9988386_8 PFAM cytochrome c, class I K08738 - - 0.00000000000000000000000000000003777 131.0
WLSH2_k127_9988386_9 membrane - - - 0.00000000000000000000000000007287 118.0
WLSH2_k127_9989826_0 Sulfatase - - - 5.208e-202 643.0
WLSH2_k127_9989826_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 484.0
WLSH2_k127_9989826_10 DoxX K15977 - - 0.00000000000000000000000000000000000000000000002757 173.0
WLSH2_k127_9989826_11 Cupin domain - - - 0.000000000000000000000000000003557 126.0
WLSH2_k127_9989826_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000006594 108.0
WLSH2_k127_9989826_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000008715 92.0
WLSH2_k127_9989826_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 344.0
WLSH2_k127_9989826_3 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 340.0
WLSH2_k127_9989826_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001127 288.0
WLSH2_k127_9989826_5 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
WLSH2_k127_9989826_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000494 280.0
WLSH2_k127_9989826_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002067 269.0
WLSH2_k127_9989826_8 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001675 277.0
WLSH2_k127_9989826_9 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001301 258.0