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Overview

ID MAG04434
Name XH3_bin.25
Sample SMP0120
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus UBA9949
Species
Assembly information
Completeness (%) 62.79
Contamination (%) 1.21
GC content (%) 55.0
N50 (bp) 4,515
Genome size (bp) 1,058,118

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1281

Gene name Description KEGG GOs EC E-value Score Sequence
XH3_k127_1056211_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.668e-309 964.0
XH3_k127_1056211_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 328.0
XH3_k127_1085140_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.927e-244 762.0
XH3_k127_1085140_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002228 268.0
XH3_k127_1085140_2 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000002445 195.0
XH3_k127_1085140_3 - - - - 0.0000000000001128 73.0
XH3_k127_1107630_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.226e-194 612.0
XH3_k127_1107630_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000000000000000000000000000000000002666 228.0
XH3_k127_1107630_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000005745 126.0
XH3_k127_1107630_3 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000002805 70.0
XH3_k127_1107630_4 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000001129 63.0
XH3_k127_112358_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003428 241.0
XH3_k127_112358_1 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
XH3_k127_112358_2 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000000000005325 111.0
XH3_k127_112358_3 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000001992 75.0
XH3_k127_1193773_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 2.188e-201 633.0
XH3_k127_1193773_1 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000005665 237.0
XH3_k127_1193773_2 Helix-turn-helix domain protein K03627 - - 0.00000000000000000000000000000000000000000000000001721 185.0
XH3_k127_1265907_0 AAA domain - - - 3.654e-240 766.0
XH3_k127_1265907_1 Belongs to the glutamate synthase family - - - 5.021e-220 693.0
XH3_k127_1265907_10 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000001663 96.0
XH3_k127_1265907_11 - - - - 0.00000000000000008395 81.0
XH3_k127_1265907_2 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 440.0
XH3_k127_1265907_3 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 390.0
XH3_k127_1265907_4 PFAM zinc iron permease K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 349.0
XH3_k127_1265907_5 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
XH3_k127_1265907_6 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 334.0
XH3_k127_1265907_7 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000004955 201.0
XH3_k127_1265907_8 - - - - 0.000000000000000000000000000000005893 138.0
XH3_k127_1265907_9 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000000000000002348 108.0
XH3_k127_1271926_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 2.287e-298 925.0
XH3_k127_1271926_1 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001199 275.0
XH3_k127_1271926_2 PFAM TspO MBR family K05770 - - 0.00000000000000000000000000000000000000000000001654 175.0
XH3_k127_1275601_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.072e-279 869.0
XH3_k127_1275601_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 520.0
XH3_k127_1275601_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 499.0
XH3_k127_1275601_3 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 362.0
XH3_k127_1275601_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 237.0
XH3_k127_1275601_5 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
XH3_k127_1275601_6 PFAM ABC transporter K16786 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
XH3_k127_1275601_7 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000002578 204.0
XH3_k127_1275601_8 PFAM BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000007339 188.0
XH3_k127_1284425_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 342.0
XH3_k127_1284425_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
XH3_k127_1288218_0 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 317.0
XH3_k127_1288218_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000001762 213.0
XH3_k127_1288218_2 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000000000006281 184.0
XH3_k127_1288218_3 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000000000000000000008315 132.0
XH3_k127_1288218_4 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000003995 117.0
XH3_k127_1288218_5 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000000000000000000008408 112.0
XH3_k127_1288218_6 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000009335 91.0
XH3_k127_1302491_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 1.692e-261 814.0
XH3_k127_1302491_1 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
XH3_k127_1302491_2 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000006686 118.0
XH3_k127_1302491_3 - - - - 0.00000000000000000000006194 101.0
XH3_k127_1308359_0 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
XH3_k127_1308359_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 417.0
XH3_k127_1308359_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 365.0
XH3_k127_1308359_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 363.0
XH3_k127_1308359_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007472 268.0
XH3_k127_1308359_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000596 211.0
XH3_k127_1308359_6 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000006636 55.0
XH3_k127_1310504_0 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000001913 110.0
XH3_k127_1310504_1 Adenosine specific kinase K09129 - - 0.00000000000000001593 83.0
XH3_k127_1310504_2 - - - - 0.000000009679 57.0
XH3_k127_1338038_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 530.0
XH3_k127_1338038_1 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000000000000008129 183.0
XH3_k127_1338038_2 Belongs to the UPF0146 family K09713 - - 0.00000000000000000000000000000000000001901 153.0
XH3_k127_1338038_3 PFAM AIR synthase related protein K07123 - - 0.0000000000000000000000000000000002184 133.0
XH3_k127_1374453_0 sensor histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 338.0
XH3_k127_1374453_1 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000006506 158.0
XH3_k127_1379920_0 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 488.0
XH3_k127_1379920_1 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 360.0
XH3_k127_1379920_2 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000001663 239.0
XH3_k127_1379920_3 PFAM sigma-70 region 4 domain protein K09714 - - 0.0000000000000000000000000000000000000000000000000000000000006716 212.0
XH3_k127_1379920_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000001034 145.0
XH3_k127_1388862_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.487e-287 891.0
XH3_k127_1388862_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000000009876 186.0
XH3_k127_1388862_2 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000000000003178 167.0
XH3_k127_1388862_3 - - - - 0.0000000000000000000000000000000001252 138.0
XH3_k127_1388862_4 Protein of unknown function DUF134 K06933 - - 0.00000001919 59.0
XH3_k127_140164_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 464.0
XH3_k127_140164_1 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 413.0
XH3_k127_140164_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
XH3_k127_140164_3 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000007204 189.0
XH3_k127_140164_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000002095 94.0
XH3_k127_140164_5 structural constituent of ribosome K02962 - - 0.00000000000000000005934 90.0
XH3_k127_14180_0 DEAD DEAH box helicase domain protein K03725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 541.0
XH3_k127_14180_1 membrane K09167 - - 0.0000000000000000000003731 103.0
XH3_k127_14180_2 - - - - 0.000004933 49.0
XH3_k127_1435703_0 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 497.0
XH3_k127_1435703_1 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 300.0
XH3_k127_1435703_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000000000000001722 123.0
XH3_k127_1435703_3 CRS1_YhbY K07574 - - 0.0000000000000000000007445 97.0
XH3_k127_1436041_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 576.0
XH3_k127_1436041_1 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 466.0
XH3_k127_1436041_2 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 299.0
XH3_k127_1436041_3 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 263.0
XH3_k127_1436041_4 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
XH3_k127_1436041_5 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000000002904 184.0
XH3_k127_1436041_6 - - - - 0.0000000000000000000000000000000003263 138.0
XH3_k127_1436041_7 TIR domain - - - 0.00000000000000000006532 94.0
XH3_k127_1449196_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 325.0
XH3_k127_1449196_1 Roadblock LC7 - - - 0.000000000000000000000000002076 123.0
XH3_k127_1449196_2 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.00000000000000003022 81.0
XH3_k127_1449196_3 Roadblock LC7 K07131 - - 0.000000983 56.0
XH3_k127_1449196_4 Histidine kinase - - - 0.00004961 52.0
XH3_k127_1533357_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.847e-317 982.0
XH3_k127_1533357_1 Belongs to the TCP-1 chaperonin family K22447 - - 3.584e-243 761.0
XH3_k127_1533357_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 595.0
XH3_k127_1533357_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 344.0
XH3_k127_1533357_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 342.0
XH3_k127_1533357_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
XH3_k127_1533357_6 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000000008413 175.0
XH3_k127_1533357_7 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000001244 132.0
XH3_k127_1533357_8 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.0000001332 55.0
XH3_k127_1584172_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1304.0
XH3_k127_1584172_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.33e-225 705.0
XH3_k127_1584172_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000003491 217.0
XH3_k127_1584172_4 - - - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
XH3_k127_1584172_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000001794 181.0
XH3_k127_1584172_6 PFAM helix-turn-helix domain protein K07729 - - 0.00000000000000000000000000004711 117.0
XH3_k127_1584172_7 Belongs to the UPF0248 family K09715 - - 0.000000000000000001188 88.0
XH3_k127_1584172_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000003117 81.0
XH3_k127_1601604_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000003746 237.0
XH3_k127_1601604_1 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000002138 211.0
XH3_k127_1602783_0 amino acid K03294 - - 4.99e-264 828.0
XH3_k127_1602783_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 478.0
XH3_k127_1602783_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 285.0
XH3_k127_1602783_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000003755 228.0
XH3_k127_1602783_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000001045 192.0
XH3_k127_1602783_5 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00002662 48.0
XH3_k127_1608190_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 1.06e-220 690.0
XH3_k127_1608190_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003966 266.0
XH3_k127_1633338_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 602.0
XH3_k127_1633338_1 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 427.0
XH3_k127_1633338_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 333.0
XH3_k127_1633338_3 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002431 258.0
XH3_k127_1633338_4 DNA polymerase LigD, polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000006799 212.0
XH3_k127_1633338_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000227 197.0
XH3_k127_1633338_6 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000001218 175.0
XH3_k127_1633338_7 protein possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000000000521 129.0
XH3_k127_1664467_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.44e-229 715.0
XH3_k127_1664467_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 472.0
XH3_k127_1664467_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000003492 190.0
XH3_k127_1664467_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000001207 175.0
XH3_k127_1664467_4 PFAM Ribosomal LX protein K02944 - - 0.000000000000000001726 86.0
XH3_k127_1768609_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1071.0
XH3_k127_1770097_0 Belongs to the glutamate synthase family - - - 3.294e-273 847.0
XH3_k127_1770097_1 PFAM glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 551.0
XH3_k127_1770097_2 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 436.0
XH3_k127_1770097_3 PFAM glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 339.0
XH3_k127_1770097_4 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000659 233.0
XH3_k127_1770097_5 PFAM PKD domain containing protein - - - 0.00000000000001291 80.0
XH3_k127_1804295_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 303.0
XH3_k127_1804295_1 permease K03299 - - 0.000000000000000000000005153 104.0
XH3_k127_1807648_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.496e-256 794.0
XH3_k127_1807648_1 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000006078 198.0
XH3_k127_1807648_2 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000000007985 166.0
XH3_k127_1807648_3 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000001897 53.0
XH3_k127_1812080_0 PFAM TrkA-N domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 477.0
XH3_k127_1812080_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000002303 96.0
XH3_k127_1822461_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 2.367e-207 653.0
XH3_k127_1822461_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000006289 149.0
XH3_k127_1822461_2 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000138 82.0
XH3_k127_1830710_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 540.0
XH3_k127_1830710_1 Mediates influx of magnesium ions K03284 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
XH3_k127_1830710_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001779 234.0
XH3_k127_1830710_3 Yip1 domain - - - 0.0000000000000000000000000000000000000003417 159.0
XH3_k127_1830710_4 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000002354 96.0
XH3_k127_1830710_5 COG1361 S-layer domain - - - 0.0000007448 53.0
XH3_k127_1889367_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 8.499e-203 635.0
XH3_k127_1889367_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 346.0
XH3_k127_1889367_2 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
XH3_k127_1889367_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000003942 101.0
XH3_k127_1889367_4 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000000006028 96.0
XH3_k127_1893880_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
XH3_k127_1893880_1 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001573 107.0
XH3_k127_1934521_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 465.0
XH3_k127_1934521_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 343.0
XH3_k127_1934521_2 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 318.0
XH3_k127_1934521_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000009625 64.0
XH3_k127_1959159_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1513.0
XH3_k127_1959159_1 PFAM Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 313.0
XH3_k127_1959159_2 tRNAHis guanylyltransferase - - - 0.000000000000000000000000003224 113.0
XH3_k127_2019799_0 permease K03299 - - 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
XH3_k127_2019799_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000001579 172.0
XH3_k127_2061766_0 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 342.0
XH3_k127_2061766_1 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009321 261.0
XH3_k127_2061766_2 - - - - 0.000000000000000000000000000000003206 130.0
XH3_k127_2061766_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000004407 133.0
XH3_k127_2103965_0 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 412.0
XH3_k127_2103965_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000008377 83.0
XH3_k127_213613_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 447.0
XH3_k127_213613_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 439.0
XH3_k127_213613_2 - - - - 0.0000000000000000007523 87.0
XH3_k127_2147695_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 542.0
XH3_k127_2147695_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000772 160.0
XH3_k127_2147695_2 SNARE associated Golgi protein K03975 - - 0.00000000004919 64.0
XH3_k127_2147695_3 Protein of unknown function (DUF447) K09154 - - 0.00007062 45.0
XH3_k127_216301_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 317.0
XH3_k127_216301_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 314.0
XH3_k127_216301_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 280.0
XH3_k127_216301_3 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000005651 209.0
XH3_k127_216301_4 - - - - 0.00000000000000000000000000000000000000000000001267 186.0
XH3_k127_216301_5 Fe-S-cluster oxidoreductase - - - 0.00000000000000000000000000000000000000000002188 164.0
XH3_k127_216301_6 - - - - 0.0000000000000003628 83.0
XH3_k127_2173859_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 357.0
XH3_k127_2173859_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 348.0
XH3_k127_2173859_2 PFAM Histone deacetylase - - - 0.000000000000006419 78.0
XH3_k127_2298546_0 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000167 147.0
XH3_k127_2298546_1 Parallel beta-helix repeats - - - 0.000000000000000000000000002729 129.0
XH3_k127_2298546_2 TPR Domain containing protein - - - 0.000000000000000001093 89.0
XH3_k127_2298546_3 - - - - 0.000000000000742 72.0
XH3_k127_231101_0 Phosphate transport regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 302.0
XH3_k127_231101_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000001894 125.0
XH3_k127_2326706_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0 1133.0
XH3_k127_2326706_1 Putative NAD(P)-binding K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009352 274.0
XH3_k127_2326706_2 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000007675 219.0
XH3_k127_2326706_3 TIR domain - - - 0.00000000000000000004483 98.0
XH3_k127_2326706_4 Domain of unknown function (DUF4405) - - - 0.000000000002025 72.0
XH3_k127_2349751_0 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 413.0
XH3_k127_2349751_1 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 407.0
XH3_k127_2349751_2 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
XH3_k127_2349751_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001578 277.0
XH3_k127_2349751_4 - - - - 0.00000000000003521 77.0
XH3_k127_2352669_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1036.0
XH3_k127_2352669_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.128e-278 858.0
XH3_k127_2352669_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000003314 96.0
XH3_k127_2352669_11 - - - - 0.00000000001152 70.0
XH3_k127_2352669_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.405e-233 740.0
XH3_k127_2352669_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 579.0
XH3_k127_2352669_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 428.0
XH3_k127_2352669_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 323.0
XH3_k127_2352669_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000000000000000001512 213.0
XH3_k127_2352669_7 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000004102 166.0
XH3_k127_2352669_8 - - - - 0.0000000000000000000000000000000002063 135.0
XH3_k127_2352669_9 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000002283 95.0
XH3_k127_2441899_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 555.0
XH3_k127_2441899_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 461.0
XH3_k127_2441899_10 - - - - 0.0000000000000006051 79.0
XH3_k127_2441899_11 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000006372 78.0
XH3_k127_2441899_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 396.0
XH3_k127_2441899_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
XH3_k127_2441899_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
XH3_k127_2441899_5 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000001146 196.0
XH3_k127_2441899_6 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.00000000000000000000000000000000000000000000000000004088 196.0
XH3_k127_2441899_7 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000143 124.0
XH3_k127_2441899_8 protein conserved in archaea - - - 0.0000000000000000000000000000002052 125.0
XH3_k127_2441899_9 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000002597 102.0
XH3_k127_2472898_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 314.0
XH3_k127_2472898_1 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
XH3_k127_2472898_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000004281 260.0
XH3_k127_2472898_3 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000000000000000000000000001201 174.0
XH3_k127_2472898_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000009311 117.0
XH3_k127_2499100_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 2.347e-198 632.0
XH3_k127_2499100_1 DNA polymerase activity K02319 - 2.7.7.7 0.000000000000000000000000000000000001393 148.0
XH3_k127_2499100_3 - - - - 0.00000000009229 64.0
XH3_k127_2499100_4 - - - - 0.0000000006462 68.0
XH3_k127_2509338_0 Predicted membrane protein (DUF2070) K08979 - - 8.569e-200 641.0
XH3_k127_2509338_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 393.0
XH3_k127_2509338_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002233 238.0
XH3_k127_2509338_3 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000000000000000003797 189.0
XH3_k127_2509338_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.000000000000000000000000002349 113.0
XH3_k127_2509338_5 Family of unknown function (DUF5350) - - - 0.000000000000000000000002148 106.0
XH3_k127_2516625_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000001013 244.0
XH3_k127_2516625_1 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000002408 205.0
XH3_k127_2516625_2 - - - - 0.00000000000000000000000000000000000000000018 163.0
XH3_k127_2516625_3 DGC domain - - - 0.00000000000000000002017 96.0
XH3_k127_25398_0 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 449.0
XH3_k127_25398_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
XH3_k127_25398_2 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000003523 223.0
XH3_k127_25398_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000005254 217.0
XH3_k127_25398_4 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000002746 216.0
XH3_k127_25398_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000002057 110.0
XH3_k127_25398_6 TPR repeat-containing protein - - - 0.0000000000000000003601 96.0
XH3_k127_2539886_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 397.0
XH3_k127_2539886_1 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000003427 241.0
XH3_k127_2560136_0 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 591.0
XH3_k127_2560136_1 Domain of unknown function (DUF362) - - - 0.00000000003419 66.0
XH3_k127_2576714_0 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 440.0
XH3_k127_2576714_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 312.0
XH3_k127_2576714_2 methanogen marker protein 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 271.0
XH3_k127_2576714_3 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
XH3_k127_2576714_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000002188 241.0
XH3_k127_2576714_5 transcription factor (CBF NF-Y) - - - 0.0000000000000000000000000002464 114.0
XH3_k127_2576714_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0005777 48.0
XH3_k127_259166_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 315.0
XH3_k127_259166_1 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000267 258.0
XH3_k127_259166_2 membrane K09167 - - 0.00000000000000000000000000000000000000000000000000000000000002282 220.0
XH3_k127_259166_3 - - - - 0.0005997 43.0
XH3_k127_2676033_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.271e-230 719.0
XH3_k127_2676033_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 347.0
XH3_k127_2676033_2 - - - - 0.0000000000000000000000000000000000936 134.0
XH3_k127_2676033_3 - - - - 0.00000000000000000000002645 100.0
XH3_k127_2676033_4 PFAM Yip1 domain - - - 0.00000000000000000004506 97.0
XH3_k127_2744398_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 4.456e-201 633.0
XH3_k127_2744398_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 585.0
XH3_k127_2744398_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 535.0
XH3_k127_2744398_3 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 286.0
XH3_k127_2744398_4 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 282.0
XH3_k127_2744398_5 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004799 270.0
XH3_k127_2744398_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000002117 187.0
XH3_k127_2744398_7 Domain of unknown function DUF123 - - - 0.000000000000000000000000000000001635 144.0
XH3_k127_2744398_8 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000002044 122.0
XH3_k127_2774495_0 SMART Elongator protein 3 MiaB NifB - - - 1.067e-240 754.0
XH3_k127_2774495_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 504.0
XH3_k127_2774495_2 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
XH3_k127_2774495_3 PFAM PRC-barrel domain - - - 0.000000000000000000000000000001471 122.0
XH3_k127_2780431_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 3.842e-289 895.0
XH3_k127_2780431_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 552.0
XH3_k127_2780431_2 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 410.0
XH3_k127_2780431_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000002858 121.0
XH3_k127_2798440_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
XH3_k127_2798440_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002994 280.0
XH3_k127_2798440_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000001142 141.0
XH3_k127_2798440_3 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000009697 130.0
XH3_k127_2842627_0 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 458.0
XH3_k127_2842627_1 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 333.0
XH3_k127_2842627_2 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000001031 180.0
XH3_k127_2858936_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1438.0
XH3_k127_2858936_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
XH3_k127_2858936_2 Protein of unknown function (DUF432) K09149 - - 0.0000000000000000000000000000000000000000000000000000000003058 210.0
XH3_k127_2858936_3 - - - - 0.000000000000000000000000000000000002271 143.0
XH3_k127_2868799_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.32e-304 942.0
XH3_k127_2868799_1 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 306.0
XH3_k127_2868799_2 binding domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001985 267.0
XH3_k127_2868799_3 Acetyl xylan esterase (AXE1) K06889 - - 0.0000000000000001194 80.0
XH3_k127_2868799_4 META domain - - - 0.0000000000000002993 83.0
XH3_k127_2868799_5 2TM domain - - - 0.000000003247 61.0
XH3_k127_2924398_0 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 377.0
XH3_k127_2924398_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003722 256.0
XH3_k127_2944739_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.796e-227 711.0
XH3_k127_2944739_1 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 569.0
XH3_k127_2944739_2 ZPR1-related zinc finger protein K06874 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 232.0
XH3_k127_2944739_3 PFAM PUA domain containing protein K07575 - - 0.00000000000000000000000000000000000000000000000000000000000000002961 227.0
XH3_k127_2944739_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN - - - 0.000000000000000000000000000000000000000000000000000000000003054 214.0
XH3_k127_2944739_5 Pfam:DUF552 K09152 - - 0.00000000000000000000000000000000000000000000000000004743 189.0
XH3_k127_2944739_6 Thioredoxin K03671 - - 0.000000000000000000000000000000000000001263 152.0
XH3_k127_2944739_7 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000000000000000000000006105 145.0
XH3_k127_2944739_8 binds to the 23S rRNA K02922 - - 0.0000000000000000000000003327 105.0
XH3_k127_2961648_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.775e-230 722.0
XH3_k127_2961648_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 269.0
XH3_k127_2961823_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 399.0
XH3_k127_2961823_1 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
XH3_k127_2961823_2 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 335.0
XH3_k127_2961823_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
XH3_k127_2961823_4 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000001093 237.0
XH3_k127_2961823_5 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000001478 187.0
XH3_k127_2961823_6 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000002742 102.0
XH3_k127_3055120_0 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 327.0
XH3_k127_3055120_1 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000009473 229.0
XH3_k127_3055120_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000007134 230.0
XH3_k127_3077046_0 PFAM Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 376.0
XH3_k127_3077046_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 345.0
XH3_k127_3077046_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000005777 166.0
XH3_k127_309512_0 phosphoesterase RecJ domain protein - - - 1.099e-198 632.0
XH3_k127_309512_1 COG1668 ABC-type Na efflux pump, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 576.0
XH3_k127_309512_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 377.0
XH3_k127_309512_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 276.0
XH3_k127_309512_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
XH3_k127_309512_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000001716 192.0
XH3_k127_31006_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 447.0
XH3_k127_31006_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 439.0
XH3_k127_31006_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
XH3_k127_31006_3 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 412.0
XH3_k127_31006_4 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
XH3_k127_31006_5 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 301.0
XH3_k127_3130240_0 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.000000000000000000000000000000000000000000000000000000000000000003841 231.0
XH3_k127_3130240_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000000003663 220.0
XH3_k127_3130240_2 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000000000000002941 154.0
XH3_k127_3130240_3 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000000000000000000000025 136.0
XH3_k127_3130240_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000000000000002826 122.0
XH3_k127_3130240_5 CRS1_YhbY K07574 - - 0.000000000000000000003628 95.0
XH3_k127_3130240_6 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000007824 88.0
XH3_k127_3130240_7 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000004048 84.0
XH3_k127_3149969_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.076e-287 899.0
XH3_k127_3149969_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 330.0
XH3_k127_3149969_2 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000001653 198.0
XH3_k127_3149969_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000000000000000000000001936 130.0
XH3_k127_315403_0 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 507.0
XH3_k127_315403_1 - - - - 0.0000000000002741 71.0
XH3_k127_315403_2 - - - - 0.0001409 46.0
XH3_k127_3169662_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 449.0
XH3_k127_3169662_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 368.0
XH3_k127_3169662_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
XH3_k127_3169662_3 COG1881 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000004363 205.0
XH3_k127_3169662_4 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000001002 123.0
XH3_k127_332412_0 PFAM Yip1 domain - - - 0.00000000000000000000000000000000008353 141.0
XH3_k127_332412_1 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.00000000000001856 73.0
XH3_k127_332412_2 Tetratricopeptide repeat - - - 0.0000001254 63.0
XH3_k127_332412_3 - - - - 0.0002925 52.0
XH3_k127_3376247_0 DEAD DEAH box helicase domain protein K03725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 446.0
XH3_k127_3376247_1 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 430.0
XH3_k127_3376247_2 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000004043 166.0
XH3_k127_3376247_3 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000000000000000000007324 148.0
XH3_k127_3438105_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 7.719e-272 847.0
XH3_k127_3438105_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 572.0
XH3_k127_3438105_2 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 375.0
XH3_k127_3438105_3 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 376.0
XH3_k127_3438105_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000003096 134.0
XH3_k127_3438105_5 PFAM type II secretion system protein E K07332 - - 0.00000000000002527 73.0
XH3_k127_3438442_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.68e-289 895.0
XH3_k127_3438442_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 293.0
XH3_k127_3438442_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000008567 99.0
XH3_k127_3455734_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1152.0
XH3_k127_3455734_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 506.0
XH3_k127_3592847_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 375.0
XH3_k127_3592847_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 309.0
XH3_k127_3592847_10 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000002962 120.0
XH3_k127_3592847_11 Phosphate-starvation-inducible E - - - 0.000000000000000000000000001412 117.0
XH3_k127_3592847_12 PFAM GCN5-related N-acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.000000000000000000000000008275 115.0
XH3_k127_3592847_13 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000008123 89.0
XH3_k127_3592847_14 - - - - 0.0000000000000007998 85.0
XH3_k127_3592847_2 PHP-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
XH3_k127_3592847_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
XH3_k127_3592847_4 PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 260.0
XH3_k127_3592847_5 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000001154 248.0
XH3_k127_3592847_6 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000001578 232.0
XH3_k127_3592847_7 Belongs to the UPF0305 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
XH3_k127_3592847_8 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000004475 183.0
XH3_k127_3592847_9 Molybdopterin converting factor K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000007314 161.0
XH3_k127_3600083_0 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
XH3_k127_3600083_1 PFAM Amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000007262 226.0
XH3_k127_3600083_2 integral membrane protein - - - 0.000000000000000000000000000002142 128.0
XH3_k127_3600083_3 transcription factor (CBF NF-Y) - - - 0.0000004232 51.0
XH3_k127_3600083_4 TIGRFAM CRISPR-associated protein K19085 - - 0.00002196 47.0
XH3_k127_3621507_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
XH3_k127_3621507_1 Domain of unknown function (DUF1917) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 294.0
XH3_k127_3621507_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000011 235.0
XH3_k127_3621507_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
XH3_k127_3621507_4 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000000344 96.0
XH3_k127_3624051_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 394.0
XH3_k127_3624051_1 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 351.0
XH3_k127_3657796_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.03e-220 705.0
XH3_k127_3657796_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 515.0
XH3_k127_3657796_10 - - - - 0.0000000000001161 76.0
XH3_k127_3657796_11 - K06193 - - 0.00000005045 64.0
XH3_k127_3657796_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 441.0
XH3_k127_3657796_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
XH3_k127_3657796_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
XH3_k127_3657796_5 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000101 201.0
XH3_k127_3657796_6 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000005958 195.0
XH3_k127_3657796_7 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000001927 186.0
XH3_k127_3657796_8 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000001835 174.0
XH3_k127_3657796_9 RuvA, C-terminal domain K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001507 163.0
XH3_k127_3664631_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 346.0
XH3_k127_3664631_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009454 277.0
XH3_k127_3664631_2 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000001229 143.0
XH3_k127_3664631_3 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000005428 123.0
XH3_k127_3665971_0 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 451.0
XH3_k127_3665971_1 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 392.0
XH3_k127_3665971_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 315.0
XH3_k127_3665971_3 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000002861 203.0
XH3_k127_3665971_4 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000001643 202.0
XH3_k127_3665971_5 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000195 165.0
XH3_k127_3665971_6 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000001731 139.0
XH3_k127_3665971_7 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000005088 112.0
XH3_k127_3677815_0 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 417.0
XH3_k127_3677815_1 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 292.0
XH3_k127_3677815_2 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005192 250.0
XH3_k127_3677815_3 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000005748 78.0
XH3_k127_3690205_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1296.0
XH3_k127_3690205_1 TGS domain protein K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 539.0
XH3_k127_3690205_2 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 410.0
XH3_k127_3690205_3 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 304.0
XH3_k127_3690205_4 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
XH3_k127_3690205_5 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000009904 184.0
XH3_k127_3696752_0 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 308.0
XH3_k127_3705024_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 601.0
XH3_k127_3705024_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 513.0
XH3_k127_3705024_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 483.0
XH3_k127_3705024_3 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 361.0
XH3_k127_3705024_4 - - - - 0.00000000000000000000000000000000006335 134.0
XH3_k127_3705024_5 - - - - 0.0000000000000005378 79.0
XH3_k127_3705024_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000001996 69.0
XH3_k127_3725439_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1603.0
XH3_k127_3725439_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 1.255e-315 970.0
XH3_k127_3725439_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.753e-207 652.0
XH3_k127_3725439_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 5.41e-202 633.0
XH3_k127_3725439_4 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 357.0
XH3_k127_3725439_5 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
XH3_k127_3725439_6 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000000000000000000006141 157.0
XH3_k127_3725439_7 Protein of unknown function (DUF473) K09135 - - 0.0000000000000000000000000000000000000006725 153.0
XH3_k127_3725439_8 - - - - 0.000000000000000000000000000000000002555 139.0
XH3_k127_3733917_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1257.0
XH3_k127_3733917_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
XH3_k127_3733917_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
XH3_k127_3733917_3 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000002764 200.0
XH3_k127_3733917_4 Ribosomal protein S23 K02973 - - 0.0000000000000000000000000000000001611 136.0
XH3_k127_3733917_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000008989 91.0
XH3_k127_3733917_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000006769 59.0
XH3_k127_3741506_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 455.0
XH3_k127_3741506_1 PFAM GTP-binding protein HSR1-related K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 344.0
XH3_k127_3741506_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 266.0
XH3_k127_3741506_3 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 257.0
XH3_k127_3741506_4 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000000000000000000000000000005487 196.0
XH3_k127_3741506_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000007255 170.0
XH3_k127_3741506_6 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000000000000001576 167.0
XH3_k127_3741506_7 Zn-ribbon containing protein K07163 - - 0.00000000000000000000000001055 113.0
XH3_k127_3771155_0 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 518.0
XH3_k127_3771155_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 325.0
XH3_k127_3771155_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
XH3_k127_3771155_3 COG0590 Cytosine adenosine deaminases K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000001109 236.0
XH3_k127_3771155_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000001835 229.0
XH3_k127_3771155_5 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000002543 215.0
XH3_k127_3771155_6 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000001033 183.0
XH3_k127_3771155_7 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000003346 90.0
XH3_k127_3789137_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 3.588e-196 617.0
XH3_k127_3789137_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001282 207.0
XH3_k127_3789137_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000003233 132.0
XH3_k127_3813745_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 391.0
XH3_k127_3813745_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
XH3_k127_3858946_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 5.679e-196 623.0
XH3_k127_3858946_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 287.0
XH3_k127_3858946_2 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000000000000000000000000000000000026 210.0
XH3_k127_3858946_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000001876 209.0
XH3_k127_3858946_4 - - - - 0.0000000000000000000000000000000000000005171 158.0
XH3_k127_3858946_5 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000000000000000000000009567 144.0
XH3_k127_3858946_6 Multisubunit Na H antiporter, MnhF subunit K05570 - - 0.000000000000000000000003667 103.0
XH3_k127_3886680_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.714e-207 647.0
XH3_k127_3886680_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 581.0
XH3_k127_3886680_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 429.0
XH3_k127_3904785_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 466.0
XH3_k127_3904785_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 426.0
XH3_k127_3904785_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
XH3_k127_3904785_3 Phosphate transport regulator - - - 0.0000000000189 71.0
XH3_k127_3911193_0 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 507.0
XH3_k127_3911193_1 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 288.0
XH3_k127_3911193_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007294 275.0
XH3_k127_3911193_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000002608 175.0
XH3_k127_3911193_4 PFAM metallophosphoesterase - - - 0.000000000000000000002142 98.0
XH3_k127_3921131_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.038e-213 663.0
XH3_k127_3921131_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 297.0
XH3_k127_40103_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 460.0
XH3_k127_40103_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
XH3_k127_40103_2 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 319.0
XH3_k127_40103_3 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
XH3_k127_40103_4 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
XH3_k127_4094346_0 Dihydrouridine synthase (Dus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 536.0
XH3_k127_4094346_1 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 379.0
XH3_k127_4094346_2 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000000000000000000009909 205.0
XH3_k127_4094346_3 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000002708 202.0
XH3_k127_4160714_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 344.0
XH3_k127_4160714_1 Nitroreductase - - - 0.000000000000000000000000000002819 130.0
XH3_k127_4160714_2 - - - - 0.0000000000000000000000000003488 121.0
XH3_k127_4162930_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009026 248.0
XH3_k127_4162930_1 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000000001591 192.0
XH3_k127_4162930_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000007988 179.0
XH3_k127_4162930_3 - - - - 0.000000000000000000000000000001047 124.0
XH3_k127_4162930_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000002955 85.0
XH3_k127_4162930_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000001034 55.0
XH3_k127_4171482_0 COGs COG0614 ABC-type Fe3 -hydroxamate transport system periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 395.0
XH3_k127_4171482_1 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
XH3_k127_4171482_2 Methyltransferase type - - - 0.000000000000000000000000000000005545 130.0
XH3_k127_4171482_3 ABC 3 transport family K02015 - - 0.0000000000000000000000000007923 113.0
XH3_k127_4186019_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 506.0
XH3_k127_4186019_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 334.0
XH3_k127_4212939_0 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 371.0
XH3_k127_4212939_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001007 230.0
XH3_k127_4212939_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0001109 47.0
XH3_k127_4275364_0 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123,K00367,K00372,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2 1.362e-205 643.0
XH3_k127_4275364_1 - - - - 0.00000000000000000000000000000000000000000000000002513 183.0
XH3_k127_4275364_2 - - - - 0.00000000000000000000653 94.0
XH3_k127_4332731_0 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 409.0
XH3_k127_4332731_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
XH3_k127_4332731_2 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
XH3_k127_4332731_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000001298 224.0
XH3_k127_4332731_4 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000006033 171.0
XH3_k127_4372032_0 transcriptional regulator, ArsR family K07013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000438 246.0
XH3_k127_4372032_1 PFAM Archaeal protein of - - - 0.000000000000000000000000000000000000339 143.0
XH3_k127_4372032_2 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000004228 141.0
XH3_k127_4372032_3 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000001026 85.0
XH3_k127_4381320_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 556.0
XH3_k127_4381320_1 Cysteine-rich small domain K08260 - 3.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
XH3_k127_4381320_2 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003133 280.0
XH3_k127_4381320_3 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000002681 105.0
XH3_k127_4381320_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000001481 94.0
XH3_k127_4381320_5 Ferredoxin K05337 - - 0.0000000000000000005184 88.0
XH3_k127_4425171_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1172.0
XH3_k127_4425171_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1074.0
XH3_k127_4425171_3 - - - - 0.000000000000000000000000000000000000000008712 162.0
XH3_k127_4425171_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000001468 100.0
XH3_k127_4425171_5 - - - - 0.0000000000000000003568 92.0
XH3_k127_4465947_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.999e-260 814.0
XH3_k127_4490985_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
XH3_k127_4490985_1 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000001285 225.0
XH3_k127_4490985_2 Cerebral endothelial cell adhesion molecule K11703 GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0007159,GO:0008150,GO:0016020,GO:0022610,GO:0044464,GO:0071944,GO:0098609 2.4.1.50 0.0000000000000005578 88.0
XH3_k127_4509646_0 PFAM amino acid permease-associated region K20265 - - 1.422e-224 704.0
XH3_k127_4509646_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000003738 175.0
XH3_k127_4509646_2 Peptidase C39 family K06992 - - 0.0000000000000000000000000000000001344 144.0
XH3_k127_4509646_3 - - - - 0.00000000000000000000000008651 113.0
XH3_k127_4509646_4 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.00000000000000000004756 89.0
XH3_k127_4547473_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 555.0
XH3_k127_4547473_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 353.0
XH3_k127_4547473_2 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000006375 182.0
XH3_k127_4547473_3 Trm112p-like protein - - - 0.00000000000000003043 85.0
XH3_k127_4581177_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 301.0
XH3_k127_4581177_1 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000002185 216.0
XH3_k127_4581177_2 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000001198 135.0
XH3_k127_4581177_3 Protein-export membrane protein SecD K03072 - - 0.000000000000000000000001647 104.0
XH3_k127_4606297_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 376.0
XH3_k127_4606297_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000618 258.0
XH3_k127_4606297_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000007039 157.0
XH3_k127_4641017_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 409.0
XH3_k127_4641017_1 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000000006464 223.0
XH3_k127_4641017_2 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000008965 194.0
XH3_k127_4644353_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 373.0
XH3_k127_4644353_1 TIGRFAM F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 334.0
XH3_k127_4644353_2 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 313.0
XH3_k127_4644353_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000006009 224.0
XH3_k127_4644353_4 - - - - 0.0000000002722 62.0
XH3_k127_4663045_0 PFAM ABC-1 domain protein K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 586.0
XH3_k127_4663045_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 481.0
XH3_k127_4663045_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 354.0
XH3_k127_4663045_3 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 302.0
XH3_k127_4663045_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
XH3_k127_4663045_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000006976 130.0
XH3_k127_4663045_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001496 98.0
XH3_k127_4663045_7 - - - - 0.0000000000000000000005214 96.0
XH3_k127_4671583_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 7.303e-231 758.0
XH3_k127_4671583_1 Protein of unknown function, DUF255 K06888 - - 4.471e-201 646.0
XH3_k127_4702882_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 449.0
XH3_k127_4702882_1 - - - - 0.000000000000000000000000000000000000000000000000000000000195 210.0
XH3_k127_4702882_2 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.0000000000000000000000000007329 115.0
XH3_k127_4702882_3 - - - - 0.0000000000000000000000006594 110.0
XH3_k127_473015_0 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 419.0
XH3_k127_473015_1 Protein of unknown function (DUF1648) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
XH3_k127_473015_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000001193 216.0
XH3_k127_473015_3 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000002009 126.0
XH3_k127_4730294_0 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 292.0
XH3_k127_4730294_1 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000000000007189 216.0
XH3_k127_4730294_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000001878 198.0
XH3_k127_4730294_3 metal-binding protein - - - 0.000000000000000000000000000001879 123.0
XH3_k127_4732184_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
XH3_k127_4732184_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000001943 176.0
XH3_k127_4746653_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 9.788e-245 767.0
XH3_k127_4746653_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.134e-215 678.0
XH3_k127_4746653_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 2.993e-201 633.0
XH3_k127_4746653_3 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 396.0
XH3_k127_4746653_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 379.0
XH3_k127_4746653_5 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000006615 192.0
XH3_k127_4747576_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 436.0
XH3_k127_4747576_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 390.0
XH3_k127_4747576_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 386.0
XH3_k127_4747576_3 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 375.0
XH3_k127_4747576_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000004495 170.0
XH3_k127_4747576_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000001476 146.0
XH3_k127_4747576_6 - - - - 0.00000000000000000000000000000009827 129.0
XH3_k127_4747576_7 but it may be involved in stabilization of the trimeric complex - - - 0.00000000000001338 74.0
XH3_k127_4747576_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000002438 74.0
XH3_k127_4762990_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 571.0
XH3_k127_4762990_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 348.0
XH3_k127_4762990_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 324.0
XH3_k127_4762990_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 311.0
XH3_k127_4762990_4 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000001017 143.0
XH3_k127_4762990_5 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000002906 139.0
XH3_k127_4762990_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000008099 130.0
XH3_k127_4763919_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.158e-213 668.0
XH3_k127_4763919_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 600.0
XH3_k127_4763919_2 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002803 269.0
XH3_k127_4763919_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000008506 200.0
XH3_k127_4763919_4 - - - - 0.00000000000000000002005 96.0
XH3_k127_4786807_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 550.0
XH3_k127_4786807_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 501.0
XH3_k127_4786807_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 462.0
XH3_k127_4786807_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 461.0
XH3_k127_4786807_4 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
XH3_k127_4786807_5 Oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
XH3_k127_4786807_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000000000000000000000000002311 168.0
XH3_k127_4786807_7 secretion by the type IV secretion system K07332 - - 0.000000000000000000000000007647 115.0
XH3_k127_4786807_8 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000003729 98.0
XH3_k127_4813488_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 568.0
XH3_k127_4813488_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
XH3_k127_4813488_2 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 349.0
XH3_k127_4813488_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 299.0
XH3_k127_4815771_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 3.999e-257 801.0
XH3_k127_4815771_1 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000005733 138.0
XH3_k127_4815771_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000008948 51.0
XH3_k127_4838200_0 Belongs to the MCM family K10726 - - 6.722e-249 775.0
XH3_k127_4838200_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 506.0
XH3_k127_4838200_2 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 336.0
XH3_k127_4887348_0 in RNase L inhibitor, RLI K06174 - - 5.228e-302 934.0
XH3_k127_4887348_1 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
XH3_k127_4887348_2 RNase L inhibitor, RLI - - - 0.000000000000000000000001474 109.0
XH3_k127_4894019_0 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
XH3_k127_4894019_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 267.0
XH3_k127_4894019_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
XH3_k127_4894019_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
XH3_k127_4906245_0 Helix-hairpin-helix domain K02347 - - 3.081e-197 629.0
XH3_k127_4906245_1 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
XH3_k127_4906245_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 325.0
XH3_k127_4906245_3 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007697 267.0
XH3_k127_4906245_4 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000008441 240.0
XH3_k127_4906245_5 iron dependent repressor K03709,K04758 - - 0.0000000000000000000000000000000000000001944 157.0
XH3_k127_4911376_0 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 337.0
XH3_k127_4911376_1 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000005919 203.0
XH3_k127_4911376_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000921 131.0
XH3_k127_4911376_3 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000009619 112.0
XH3_k127_4932728_0 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 516.0
XH3_k127_4932728_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 364.0
XH3_k127_4932728_2 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 301.0
XH3_k127_4932728_3 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002673 269.0
XH3_k127_4932728_4 amidohydrolase - - - 0.00001304 49.0
XH3_k127_4933680_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 538.0
XH3_k127_4933680_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 318.0
XH3_k127_4933680_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000006693 184.0
XH3_k127_4933680_3 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000000001449 106.0
XH3_k127_4933680_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000005376 66.0
XH3_k127_4954_0 PFAM Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 357.0
XH3_k127_4954_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
XH3_k127_4954_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000001297 215.0
XH3_k127_4954_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000003176 181.0
XH3_k127_4954_4 Small multi-drug export protein - - - 0.00000000000000000000000000000000000000005225 160.0
XH3_k127_4967097_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
XH3_k127_4967097_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003501 270.0
XH3_k127_4967097_2 - - - - 0.0000000000000005571 81.0
XH3_k127_4968422_0 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000217 268.0
XH3_k127_4968422_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000005866 204.0
XH3_k127_4968422_2 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000001696 97.0
XH3_k127_4968422_3 - - - - 0.000000000000003073 86.0
XH3_k127_4968422_4 Short repeat of unknown function (DUF308) - - - 0.0001721 52.0
XH3_k127_5028884_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 498.0
XH3_k127_5028884_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
XH3_k127_5028884_2 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000001889 144.0
XH3_k127_5031885_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 8.777e-211 662.0
XH3_k127_5031885_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 584.0
XH3_k127_5031885_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 528.0
XH3_k127_5031885_3 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 443.0
XH3_k127_5031885_4 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 393.0
XH3_k127_5031885_5 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 367.0
XH3_k127_5031885_6 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 284.0
XH3_k127_5031885_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 265.0
XH3_k127_5031885_8 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000363 90.0
XH3_k127_5084965_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 8.416e-300 927.0
XH3_k127_5084965_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.549e-256 796.0
XH3_k127_5084965_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 378.0
XH3_k127_5084965_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 305.0
XH3_k127_5084965_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000000000001047 138.0
XH3_k127_5084965_5 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000001351 124.0
XH3_k127_5084965_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000007773 121.0
XH3_k127_5084965_7 ATP synthase subunit C K02124 - - 0.00000000000000000000653 94.0
XH3_k127_5108027_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 561.0
XH3_k127_5108027_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 370.0
XH3_k127_5108027_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000000000001285 125.0
XH3_k127_5108027_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000000000757 95.0
XH3_k127_5108027_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 341.0
XH3_k127_5108027_3 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 323.0
XH3_k127_5108027_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005064 273.0
XH3_k127_5108027_5 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006044 244.0
XH3_k127_5108027_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000001317 220.0
XH3_k127_5108027_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000502 217.0
XH3_k127_5108027_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000003111 207.0
XH3_k127_5108027_9 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000000002899 176.0
XH3_k127_516140_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 464.0
XH3_k127_516140_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000001426 189.0
XH3_k127_516140_2 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000000000000003891 156.0
XH3_k127_516140_3 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000000000000000000002347 115.0
XH3_k127_516140_4 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000005576 97.0
XH3_k127_517059_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 594.0
XH3_k127_517059_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 555.0
XH3_k127_517059_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000003575 154.0
XH3_k127_517059_3 helicase activity K06915 - - 0.00000007658 55.0
XH3_k127_5224531_0 helicase activity K06915,K19172 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
XH3_k127_5224531_1 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000009181 126.0
XH3_k127_5224531_2 HD domain K01139 - 2.7.6.5,3.1.7.2 0.000000000001859 76.0
XH3_k127_5307495_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 7.765e-201 636.0
XH3_k127_5307495_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 359.0
XH3_k127_5307495_2 - - - - 0.000000000000000000003003 97.0
XH3_k127_5307495_3 - - - - 0.0000000001452 61.0
XH3_k127_5336785_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001325 278.0
XH3_k127_5336785_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000007297 165.0
XH3_k127_5336785_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000001225 114.0
XH3_k127_5367300_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.023e-211 670.0
XH3_k127_5374548_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
XH3_k127_5374548_1 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
XH3_k127_5374548_2 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000002462 156.0
XH3_k127_5387192_0 PFAM PilT protein domain protein K06865 - - 7.899e-304 941.0
XH3_k127_5387192_1 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000000000000000000000000000000000000000000000000000003637 261.0
XH3_k127_5387192_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000009868 187.0
XH3_k127_5387192_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000005198 149.0
XH3_k127_5387192_4 - - - - 0.0000000000000003234 83.0
XH3_k127_5401922_1 - - - - 0.000000000000002453 82.0
XH3_k127_5401922_2 - - - - 0.000000005289 66.0
XH3_k127_5401922_3 - - - - 0.00000004051 63.0
XH3_k127_5436218_0 DEAD DEAH box helicase domain protein K10896 - - 3.163e-264 827.0
XH3_k127_5436218_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 7.077e-241 752.0
XH3_k127_5509804_0 Involved in cell shape control K22222 - - 3.051e-198 623.0
XH3_k127_5509804_1 - - - - 0.0000000000000000000001634 103.0
XH3_k127_5509804_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0006116,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019362,GO:0019637,GO:0019674,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0046483,GO:0046496,GO:0048037,GO:0048038,GO:0048039,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072524,GO:0098573,GO:0098798,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.5.5.1 0.0008684 44.0
XH3_k127_5510900_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 540.0
XH3_k127_5510900_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 481.0
XH3_k127_5510900_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 457.0
XH3_k127_5510900_3 - - - - 0.00000000000000000000000000000000000000001348 161.0
XH3_k127_552411_0 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 384.0
XH3_k127_552411_1 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 384.0
XH3_k127_552411_2 Protein of unknown function (DUF460) K09150 - - 0.0000000000000000000000000001473 119.0
XH3_k127_5579281_0 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 311.0
XH3_k127_5579281_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000001014 55.0
XH3_k127_5734693_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.759e-211 668.0
XH3_k127_5734693_1 PFAM peptidase U32 K08303 - - 3.035e-211 686.0
XH3_k127_5734693_10 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000002652 195.0
XH3_k127_5734693_11 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000002248 163.0
XH3_k127_5734693_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000001251 147.0
XH3_k127_5734693_2 PFAM PUA domain containing protein K07557 - 2.6.1.97 2.507e-206 656.0
XH3_k127_5734693_3 PFAM alanine dehydrogenase PNT domain protein K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 587.0
XH3_k127_5734693_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 484.0
XH3_k127_5734693_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 453.0
XH3_k127_5734693_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 303.0
XH3_k127_5734693_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006324 246.0
XH3_k127_5734693_8 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000002929 241.0
XH3_k127_5734693_9 PFAM NAD(P) transhydrogenase, beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000001103 197.0
XH3_k127_5797833_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 509.0
XH3_k127_5797833_1 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 306.0
XH3_k127_5797833_2 PFAM Cation K03498 - - 0.0000000000000000000008007 100.0
XH3_k127_5919189_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 306.0
XH3_k127_5919189_1 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
XH3_k127_5919189_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000003042 133.0
XH3_k127_5933610_0 Domain of unknown function DUF128 K21640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 332.0
XH3_k127_5933610_1 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 299.0
XH3_k127_5933610_2 PFAM transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000001336 218.0
XH3_k127_5967100_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 9.344e-197 627.0
XH3_k127_5967100_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 385.0
XH3_k127_5967100_2 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006945 250.0
XH3_k127_5967100_3 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
XH3_k127_5967100_4 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
XH3_k127_5967100_5 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
XH3_k127_5967100_6 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000000000000000003251 149.0
XH3_k127_5967100_7 PFAM Uncharacterised conserved protein UCP006577 - - - 0.0000000000000000916 83.0
XH3_k127_5967100_8 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K07025 - - 0.0000000000000002557 82.0
XH3_k127_5967100_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000006418 51.0
XH3_k127_5994130_0 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 464.0
XH3_k127_5994130_1 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 368.0
XH3_k127_5994130_2 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 322.0
XH3_k127_5994130_3 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000000000002306 185.0
XH3_k127_5994130_4 protein conserved in archaea K09723 - - 0.0000000000000000000000000006838 117.0
XH3_k127_5994130_5 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000003186 96.0
XH3_k127_5994130_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000002307 75.0
XH3_k127_6001196_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 469.0
XH3_k127_6001196_1 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 417.0
XH3_k127_6001196_10 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000003022 81.0
XH3_k127_6001196_11 transcriptional regulators K03724 - - 0.00000000000000003361 83.0
XH3_k127_6001196_12 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.00005131 46.0
XH3_k127_6001196_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 385.0
XH3_k127_6001196_3 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 341.0
XH3_k127_6001196_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 308.0
XH3_k127_6001196_5 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 267.0
XH3_k127_6001196_6 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002987 229.0
XH3_k127_6001196_7 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000001432 166.0
XH3_k127_6001196_8 - - - - 0.00000000000000000000000000000000000003467 151.0
XH3_k127_6001196_9 signal-transduction protein containing cAMP-binding and CBS domains K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.0000000000000000000000000000000000938 138.0
XH3_k127_6037341_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
XH3_k127_6037341_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 312.0
XH3_k127_6037341_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
XH3_k127_6037341_3 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000002326 172.0
XH3_k127_6037341_4 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000377 158.0
XH3_k127_6037341_5 Transcriptional regulator K07108 - - 0.0000000000000000000000000000001503 126.0
XH3_k127_6037341_6 transcriptional regulators K03724 - - 0.0000000000000000000000000002799 115.0
XH3_k127_6037341_7 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00000000000000000000000321 106.0
XH3_k127_6041369_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 289.0
XH3_k127_6041369_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 276.0
XH3_k127_6041369_2 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000000005802 162.0
XH3_k127_6070423_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 554.0
XH3_k127_6070423_1 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 297.0
XH3_k127_6070423_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
XH3_k127_6070423_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000006915 190.0
XH3_k127_6070423_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000000000000004381 173.0
XH3_k127_6070423_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000002328 166.0
XH3_k127_6070423_6 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000000003264 160.0
XH3_k127_6077070_0 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000006198 179.0
XH3_k127_6077070_1 - - - - 0.0000000000000000000000000000000000000000001175 167.0
XH3_k127_6077070_2 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000000000000000000000001118 149.0
XH3_k127_6077070_3 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000006265 115.0
XH3_k127_6077070_4 META domain - - - 0.0000000000000000000002154 102.0
XH3_k127_6077070_5 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.00000007973 53.0
XH3_k127_6077070_6 bile acid:sodium symporter activity K03453 - - 0.000000109 57.0
XH3_k127_6084213_0 SMART Elongator protein 3 MiaB NifB - - - 9.916e-260 814.0
XH3_k127_6084213_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 572.0
XH3_k127_6084213_10 - - - - 0.0000000002417 68.0
XH3_k127_6084213_2 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 404.0
XH3_k127_6084213_3 methanogenesis marker protein 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 344.0
XH3_k127_6084213_4 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 342.0
XH3_k127_6084213_5 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 283.0
XH3_k127_6084213_6 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001023 244.0
XH3_k127_6084213_7 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000000000000000000000000000000000000000000000000000002162 212.0
XH3_k127_6084213_8 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000000001218 175.0
XH3_k127_6084213_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001375 172.0
XH3_k127_6098871_0 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 591.0
XH3_k127_6098871_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
XH3_k127_6098871_2 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002648 241.0
XH3_k127_6098871_3 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000000000000000000000000000000002025 217.0
XH3_k127_6098871_4 PFAM ABC transporter K00400 - - 0.00000000000000000000000000000000004834 134.0
XH3_k127_6138022_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 3.888e-196 615.0
XH3_k127_6138022_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000002992 203.0
XH3_k127_6138022_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000003873 188.0
XH3_k127_618766_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 410.0
XH3_k127_618766_1 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000007981 124.0
XH3_k127_618766_2 PFAM peptidase U32 K08303 - - 0.000000000000000000002412 96.0
XH3_k127_618766_3 - - - - 0.00000000000000001034 86.0
XH3_k127_621129_0 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 442.0
XH3_k127_621129_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
XH3_k127_6223752_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 443.0
XH3_k127_6291367_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 329.0
XH3_k127_6291367_1 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001126 277.0
XH3_k127_6291367_2 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000004349 158.0
XH3_k127_6322333_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 547.0
XH3_k127_6322333_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 425.0
XH3_k127_6322333_2 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000001442 227.0
XH3_k127_6322333_3 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000001818 125.0
XH3_k127_6336600_0 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 524.0
XH3_k127_6336600_1 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003444 281.0
XH3_k127_6410722_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 494.0
XH3_k127_6410722_1 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
XH3_k127_6410722_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000001655 205.0
XH3_k127_6417194_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 2.786e-211 665.0
XH3_k127_6417194_1 TIGRFAM UbiD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 564.0
XH3_k127_6417194_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 480.0
XH3_k127_6417194_3 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 406.0
XH3_k127_6417194_4 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 376.0
XH3_k127_6417194_5 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 334.0
XH3_k127_6417194_6 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000004014 193.0
XH3_k127_6417194_7 - - - - 0.0000000000000000000000000000000000244 141.0
XH3_k127_6417194_8 Protein of unknown function DUF86 K07075 - - 0.00000000000000000000009675 106.0
XH3_k127_6417194_9 Domain of unknown function (DUF3821) - - - 0.0000000000008623 76.0
XH3_k127_643079_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 367.0
XH3_k127_643079_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
XH3_k127_643079_2 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000002133 119.0
XH3_k127_64645_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 512.0
XH3_k127_64645_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 465.0
XH3_k127_64645_2 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 375.0
XH3_k127_64645_3 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
XH3_k127_64645_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000001113 207.0
XH3_k127_64645_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000001383 149.0
XH3_k127_64645_6 PFAM Yip1 domain - - - 0.0000000000000000000000000003797 117.0
XH3_k127_64645_7 CHAT domain - - - 0.00000000000000000000000008551 118.0
XH3_k127_64645_8 - - - - 0.000000000006417 70.0
XH3_k127_6467946_0 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 358.0
XH3_k127_6467946_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 268.0
XH3_k127_6467946_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000243 221.0
XH3_k127_6467946_3 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000000000002403 154.0
XH3_k127_6467946_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000000006101 155.0
XH3_k127_6467946_5 Probably involved in the biogenesis of the ribosome K14561 - - 0.000000000000000000005855 98.0
XH3_k127_6467946_6 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000005004 89.0
XH3_k127_6467946_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000000000000006902 90.0
XH3_k127_6676915_0 PFAM amino acid permease-associated region K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 533.0
XH3_k127_6676915_1 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 508.0
XH3_k127_6752320_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 483.0
XH3_k127_6752320_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001282 270.0
XH3_k127_6752320_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000005077 242.0
XH3_k127_6752320_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000741 121.0
XH3_k127_6809223_0 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 365.0
XH3_k127_6809223_2 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.00000000007846 64.0
XH3_k127_6897548_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 339.0
XH3_k127_6897548_1 - - - - 0.000000000000000007597 86.0
XH3_k127_6929952_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 423.0
XH3_k127_6929952_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.0000000000000000001099 89.0
XH3_k127_6975938_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 508.0
XH3_k127_6975938_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001397 261.0
XH3_k127_6975938_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000002556 204.0
XH3_k127_6994820_0 PFAM phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 548.0
XH3_k127_6994820_1 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002093 264.0
XH3_k127_6994820_2 COG1202 Superfamily II helicase, archaea-specific - - - 0.00000000000000000000000000000000000000000000000000000000003151 208.0
XH3_k127_6994820_3 - - - - 0.00000000007836 68.0
XH3_k127_7003868_0 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 288.0
XH3_k127_7003868_1 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008263 261.0
XH3_k127_7003868_2 PBP superfamily domain K05772 - - 0.000000000000000000002643 96.0
XH3_k127_7010592_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 556.0
XH3_k127_7010592_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 537.0
XH3_k127_7010592_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 391.0
XH3_k127_7010592_3 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000001301 237.0
XH3_k127_7021873_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 454.0
XH3_k127_7021873_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 422.0
XH3_k127_7021873_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 404.0
XH3_k127_7021873_3 Putative auto-transporter adhesin, head GIN domain - - - 0.00000005049 61.0
XH3_k127_7027853_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1251.0
XH3_k127_7027853_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.752e-227 712.0
XH3_k127_7027853_2 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 322.0
XH3_k127_7027853_3 PFAM regulatory protein, ArsR K07721 - - 0.00000000000000000000000000000000000000000000000000000000000001953 220.0
XH3_k127_7027853_4 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000002106 119.0
XH3_k127_7027853_5 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000007431 108.0
XH3_k127_7043433_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1061.0
XH3_k127_7043433_1 PFAM ferredoxin-dependent glutamate synthase - - - 1.791e-271 840.0
XH3_k127_7043433_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 530.0
XH3_k127_7043433_3 4-Hydroxyphenylpyruvate dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 405.0
XH3_k127_7043433_4 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
XH3_k127_7043433_5 prohibitin homologues - - - 0.000000000000000000000000006687 116.0
XH3_k127_7043433_6 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000001682 94.0
XH3_k127_7066023_0 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 536.0
XH3_k127_7066023_1 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 431.0
XH3_k127_7066023_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 384.0
XH3_k127_7066023_3 - - - - 0.00000000000000000000000000000000000000000000000000000004885 199.0
XH3_k127_7066023_4 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000008992 176.0
XH3_k127_7066023_5 small multi-drug export - - - 0.000000000000000000000000000000000002389 146.0
XH3_k127_7089232_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
XH3_k127_7089232_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 417.0
XH3_k127_7089232_2 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000005346 130.0
XH3_k127_7100337_0 PFAM ABC transporter K00400 - - 1.647e-219 687.0
XH3_k127_7100337_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 529.0
XH3_k127_7100337_2 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
XH3_k127_7100337_3 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 386.0
XH3_k127_7100337_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
XH3_k127_7107312_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.088e-314 974.0
XH3_k127_7107312_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 603.0
XH3_k127_7107312_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 286.0
XH3_k127_7107312_3 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.000000000000000000000000000000000000000000000000000009709 197.0
XH3_k127_7120010_0 COG0477 Permeases of the major facilitator superfamily K08177 - - 1.446e-201 635.0
XH3_k127_7120010_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 289.0
XH3_k127_7120010_2 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 289.0
XH3_k127_7120010_3 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000002981 172.0
XH3_k127_7120010_4 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000216 150.0
XH3_k127_7120010_5 Uracil DNA glycosylase superfamily K03649 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0140097,GO:1901360 3.2.2.28 0.0000000000000000000000000000000004128 138.0
XH3_k127_7120010_6 Transcriptional regulator K07729 - - 0.000000000000000000000001389 104.0
XH3_k127_7120010_7 - - - - 0.000000000003744 74.0
XH3_k127_7120010_8 O-methyltransferase K15256 - - 0.000003043 49.0
XH3_k127_7128146_0 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 441.0
XH3_k127_7128146_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001782 245.0
XH3_k127_7128146_2 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000561 164.0
XH3_k127_7128146_3 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000002619 119.0
XH3_k127_7128146_4 Rhodanese Homology Domain - - - 0.0000000000000000000000001133 111.0
XH3_k127_7128146_5 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000022 96.0
XH3_k127_7133669_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 2.18e-212 668.0
XH3_k127_7133669_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 379.0
XH3_k127_7133669_2 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.0000000001804 61.0
XH3_k127_7146992_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 4.516e-248 783.0
XH3_k127_7146992_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004335 298.0
XH3_k127_7146992_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000002797 207.0
XH3_k127_7149075_0 PFAM ribonuclease II K01147 - 3.1.13.1 3.506e-215 682.0
XH3_k127_7149075_1 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000004906 97.0
XH3_k127_7149075_2 - - - - 0.00000002337 61.0
XH3_k127_7200972_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 446.0
XH3_k127_7200972_1 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000005492 119.0
XH3_k127_7234519_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 334.0
XH3_k127_7234519_1 Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA K06947 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019205,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0051731,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000286 190.0
XH3_k127_7257819_0 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
XH3_k127_7257819_1 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000003038 198.0
XH3_k127_7257819_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000005094 83.0
XH3_k127_7268836_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 375.0
XH3_k127_7268836_1 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 362.0
XH3_k127_7268836_10 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000008603 70.0
XH3_k127_7268836_11 CARDB - - - 0.00001799 57.0
XH3_k127_7268836_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000009 226.0
XH3_k127_7268836_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000198 154.0
XH3_k127_7268836_4 cellulose binding - - - 0.0000000000000000000000000000000005904 149.0
XH3_k127_7268836_5 Domain of unknown function (DUF333) K09712 - - 0.000000000000000000000000000004584 136.0
XH3_k127_7268836_6 Large-conductance mechanosensitive channel, MscL K03282 - - 0.000000000000000000008115 94.0
XH3_k127_7268836_7 META domain - - - 0.0000000000000002619 93.0
XH3_k127_7268836_8 - - - - 0.0000000000000006957 84.0
XH3_k127_7268836_9 Protein of unknown function (DUF1566) - - - 0.0000000000000151 87.0
XH3_k127_7349114_0 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123,K00367,K00372,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2 0.0 1057.0
XH3_k127_7349114_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 475.0
XH3_k127_7349114_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 304.0
XH3_k127_7349114_3 PFAM TPR repeat-containing protein - - - 0.00000000000000006612 86.0
XH3_k127_7349114_4 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000001692 56.0
XH3_k127_7372159_0 Protein of unknown function (DUF460) K09150 - - 5.581e-234 738.0
XH3_k127_7372159_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 326.0
XH3_k127_7386873_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 4.107e-270 844.0
XH3_k127_7386873_1 KH domain protein K06961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
XH3_k127_7386873_2 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000002646 176.0
XH3_k127_7408938_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1404.0
XH3_k127_7408938_1 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000954 272.0
XH3_k127_7408938_2 zinc finger, SWIM - - - 0.000000000000000000000000000000006976 130.0
XH3_k127_7408938_3 Helix-turn-helix domain - - - 0.00000006263 54.0
XH3_k127_7408938_4 PFAM CBS domain - - - 0.0003245 43.0
XH3_k127_7430419_0 LOR SDH bifunctional enzyme conserved - - - 1.026e-197 627.0
XH3_k127_7430419_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 414.0
XH3_k127_7430419_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 357.0
XH3_k127_7430419_3 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
XH3_k127_7430419_4 - - - - 0.000000000000000000000000000000000000000000000000009776 191.0
XH3_k127_7430419_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000856 62.0
XH3_k127_7449550_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 6.881e-235 736.0
XH3_k127_7449550_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 5.381e-233 730.0
XH3_k127_7449550_10 - K00960 - 2.7.7.6 0.000000000000000000000001262 105.0
XH3_k127_7449550_11 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000209 87.0
XH3_k127_7449550_12 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000004415 75.0
XH3_k127_7449550_2 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 521.0
XH3_k127_7449550_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 505.0
XH3_k127_7449550_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 278.0
XH3_k127_7449550_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008786 245.0
XH3_k127_7449550_6 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000008868 218.0
XH3_k127_7449550_7 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000009924 181.0
XH3_k127_7449550_8 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000004293 166.0
XH3_k127_7449550_9 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000009226 130.0
XH3_k127_751445_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.1e-253 790.0
XH3_k127_751445_1 AMP-binding enzyme - - - 3.137e-217 682.0
XH3_k127_751445_10 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002877 267.0
XH3_k127_751445_11 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 258.0
XH3_k127_751445_12 Oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001954 257.0
XH3_k127_751445_13 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001059 248.0
XH3_k127_751445_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001251 251.0
XH3_k127_751445_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 239.0
XH3_k127_751445_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
XH3_k127_751445_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 238.0
XH3_k127_751445_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000000000001599 231.0
XH3_k127_751445_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000002266 232.0
XH3_k127_751445_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 472.0
XH3_k127_751445_20 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
XH3_k127_751445_21 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000000000000000001414 226.0
XH3_k127_751445_22 binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000000000000000001411 220.0
XH3_k127_751445_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000001572 216.0
XH3_k127_751445_24 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000009263 219.0
XH3_k127_751445_25 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000005798 194.0
XH3_k127_751445_26 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000006927 192.0
XH3_k127_751445_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000000001284 186.0
XH3_k127_751445_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002732 165.0
XH3_k127_751445_29 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.000000000000000000000000000000000000000005834 156.0
XH3_k127_751445_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 416.0
XH3_k127_751445_30 PFAM Ribosomal protein K02912 - - 0.00000000000000000000000000000000000000003411 155.0
XH3_k127_751445_31 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.00000000000000000000000000008876 117.0
XH3_k127_751445_32 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000000000000356 110.0
XH3_k127_751445_33 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.0000000000000000000000003117 105.0
XH3_k127_751445_34 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000000481 102.0
XH3_k127_751445_35 PBS lyase HEAT-like repeat - - - 0.000000000000006584 81.0
XH3_k127_751445_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 371.0
XH3_k127_751445_5 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 363.0
XH3_k127_751445_6 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 365.0
XH3_k127_751445_7 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
XH3_k127_751445_8 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 353.0
XH3_k127_751445_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002438 281.0
XH3_k127_7537577_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 467.0
XH3_k127_7537577_1 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
XH3_k127_7537577_2 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
XH3_k127_7607307_0 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000001968 228.0
XH3_k127_7607307_1 Domain of unknown function (DUF333) K09712 - - 0.0000000000000000000000000000000000001576 147.0
XH3_k127_7607307_2 - - - - 0.00000000000001968 78.0
XH3_k127_7607307_3 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000004303 83.0
XH3_k127_7607307_4 TIR domain - - - 0.00000000000008951 78.0
XH3_k127_7612545_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 326.0
XH3_k127_7612545_1 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 311.0
XH3_k127_7612545_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000002166 202.0
XH3_k127_7648996_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 333.0
XH3_k127_7648996_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000002769 176.0
XH3_k127_7648996_2 - - - - 0.0000000000000009024 81.0
XH3_k127_7670040_0 PFAM CBS domain - - - 1.133e-251 783.0
XH3_k127_7670040_1 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 265.0
XH3_k127_7670040_2 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000216 245.0
XH3_k127_7670040_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000002625 183.0
XH3_k127_7670040_4 - - - - 0.00000000000000000000000000001916 122.0
XH3_k127_7670040_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000001245 86.0
XH3_k127_7670040_6 - - - - 0.000000000000000003523 87.0
XH3_k127_7670040_7 NIF3 (NGG1p interacting factor 3) - - - 0.00000005622 55.0
XH3_k127_7818093_0 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 428.0
XH3_k127_7818093_1 Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 387.0
XH3_k127_7818093_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
XH3_k127_7818093_3 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 322.0
XH3_k127_7818093_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007774 261.0
XH3_k127_7969811_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 437.0
XH3_k127_7969811_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000000125 192.0
XH3_k127_7988602_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 407.0
XH3_k127_7988602_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000009116 263.0
XH3_k127_7988602_2 methylase K00571 - 2.1.1.72 0.00000000000000000001041 95.0
XH3_k127_8004627_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.466e-301 942.0
XH3_k127_8004627_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 4.715e-203 635.0
XH3_k127_8004627_2 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000000002599 132.0
XH3_k127_8004627_3 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000003569 115.0
XH3_k127_8004627_4 B-block binding subunit of TFIIIC - - - 0.000000000000004266 77.0
XH3_k127_8004627_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000003292 60.0
XH3_k127_8020582_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 582.0
XH3_k127_8020582_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 345.0
XH3_k127_8020582_2 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
XH3_k127_8020582_3 - - - - 0.00000000000000000000000000000000001959 137.0
XH3_k127_8020582_4 - - - - 0.0000000000000002747 84.0
XH3_k127_8030599_0 AAA domain K07321 - - 0.0000000000000000000000000000004242 125.0
XH3_k127_8030599_1 VIT family - - - 0.0000002049 61.0
XH3_k127_806978_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1005.0
XH3_k127_8168825_0 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
XH3_k127_8168825_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 340.0
XH3_k127_8168825_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004739 278.0
XH3_k127_8168825_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000001956 219.0
XH3_k127_8168825_4 - - - - 0.00000000000000000000000000000000000000009613 154.0
XH3_k127_8168825_5 PDGLE domain K02009 - - 0.000000000000000002614 96.0
XH3_k127_8194376_0 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
XH3_k127_8194376_1 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000002201 233.0
XH3_k127_8194376_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
XH3_k127_8194376_3 Glutaredoxin - - - 0.00000000000000000000000000000000003061 136.0
XH3_k127_8194376_4 - - - - 0.0000000000000000000000000000000002824 135.0
XH3_k127_8194376_5 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000009721 65.0
XH3_k127_8279695_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
XH3_k127_8279695_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000001325 179.0
XH3_k127_8294403_0 Uncharacterized membrane protein (DUF2298) - - - 1.496e-220 704.0
XH3_k127_8294403_1 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
XH3_k127_8294403_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
XH3_k127_8294403_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000004591 228.0
XH3_k127_8294403_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000006733 199.0
XH3_k127_8294403_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000007896 200.0
XH3_k127_8294403_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000002887 134.0
XH3_k127_8294403_7 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000000007774 119.0
XH3_k127_8320957_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 335.0
XH3_k127_8320957_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000000000000001022 171.0
XH3_k127_8320957_2 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.00000000000000000000000000000000000003076 148.0
XH3_k127_8320957_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000002326 122.0
XH3_k127_8334808_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.166e-209 662.0
XH3_k127_8334808_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.604e-204 642.0
XH3_k127_8334808_2 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 371.0
XH3_k127_8334808_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005876 279.0
XH3_k127_8334808_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001442 114.0
XH3_k127_8334808_5 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000001103 95.0
XH3_k127_8341236_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 482.0
XH3_k127_8341236_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
XH3_k127_8341236_2 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000001491 168.0
XH3_k127_8374762_0 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
XH3_k127_8374762_1 - - - - 0.0000000000000000000000000000000000000000009467 170.0
XH3_k127_8374762_2 - K16923 - - 0.0000000000004474 75.0
XH3_k127_8374762_3 cell adhesion involved in biofilm formation - - - 0.000000000001514 79.0
XH3_k127_8421857_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1030.0
XH3_k127_8421857_1 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
XH3_k127_8421857_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004331 237.0
XH3_k127_8421857_3 HEAT repeats - - - 0.000000000000000000000000000000000000002386 154.0
XH3_k127_8454549_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 560.0
XH3_k127_8454549_1 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 511.0
XH3_k127_8454549_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
XH3_k127_8454549_3 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000393 126.0
XH3_k127_8519806_0 KH, type 1, domain K07041 - - 1.157e-248 769.0
XH3_k127_8519806_1 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 306.0
XH3_k127_8519806_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 303.0
XH3_k127_8519806_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
XH3_k127_8519806_4 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000004215 224.0
XH3_k127_8519806_5 iron dependent repressor K03709 - - 0.0000003625 52.0
XH3_k127_8631298_0 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000002194 168.0
XH3_k127_8631298_1 Small multi-drug export protein - - - 0.00000000000000000000000000000000000000000009351 165.0
XH3_k127_8631298_2 - - - - 0.00000000002731 70.0
XH3_k127_8648307_0 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000003329 168.0
XH3_k127_8648307_1 Flavodoxin - - - 0.0000000000000000000000000009445 119.0
XH3_k127_8678922_0 Heat shock 70 kDa protein K04043 - - 3.731e-296 913.0
XH3_k127_8678922_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
XH3_k127_8678922_2 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.00000000000007144 72.0
XH3_k127_8679868_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 455.0
XH3_k127_8679868_1 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001092 249.0
XH3_k127_8679868_2 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000000000000001785 190.0
XH3_k127_8681997_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 536.0
XH3_k127_8681997_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 505.0
XH3_k127_8681997_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 373.0
XH3_k127_8681997_3 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 305.0
XH3_k127_8681997_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000001215 234.0
XH3_k127_8681997_5 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.000000000000000000000000000000000000000000000000000000002425 206.0
XH3_k127_8701195_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 436.0
XH3_k127_8701195_1 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000001939 232.0
XH3_k127_8701195_2 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000005649 174.0
XH3_k127_8701195_3 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000001456 104.0
XH3_k127_8800920_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 448.0
XH3_k127_8800920_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000001792 197.0
XH3_k127_8846167_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1713.0
XH3_k127_8846167_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 527.0
XH3_k127_8846167_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 331.0
XH3_k127_8846167_3 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 312.0
XH3_k127_8891682_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 397.0
XH3_k127_8891682_1 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 380.0
XH3_k127_8891682_10 transcription factor (CBF NF-Y) - - - 0.0000000000000000000000002176 106.0
XH3_k127_8891682_11 - - - - 0.000000000000000008595 85.0
XH3_k127_8891682_12 - - - - 0.00000000000000001968 84.0
XH3_k127_8891682_2 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 308.0
XH3_k127_8891682_3 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 291.0
XH3_k127_8891682_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
XH3_k127_8891682_5 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000001446 214.0
XH3_k127_8891682_6 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000000000000000000000000000000000000004953 172.0
XH3_k127_8891682_7 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000002944 138.0
XH3_k127_8891682_8 - - - - 0.000000000000000000000000001794 113.0
XH3_k127_8891682_9 - - - - 0.0000000000000000000000001765 109.0
XH3_k127_8909715_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 419.0
XH3_k127_8909715_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000104 132.0
XH3_k127_8988823_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.309e-233 729.0
XH3_k127_8988823_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.8e-224 700.0
XH3_k127_8988823_2 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
XH3_k127_8988823_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.00000000000000000000000000000000000000000000000000001258 194.0
XH3_k127_9047418_0 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 378.0
XH3_k127_9047418_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 370.0
XH3_k127_9047418_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000005864 154.0
XH3_k127_9047418_3 - - - - 0.000000000000000000000003009 107.0
XH3_k127_9108217_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 2.046e-267 839.0
XH3_k127_9108217_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
XH3_k127_9108217_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000005293 268.0
XH3_k127_9108217_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000001855 154.0
XH3_k127_9108217_4 - - - - 0.000000000000000006154 89.0
XH3_k127_923756_0 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 417.0
XH3_k127_923756_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 368.0
XH3_k127_923756_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009154 278.0
XH3_k127_923756_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000001659 136.0
XH3_k127_923756_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000257 89.0
XH3_k127_96094_0 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 514.0
XH3_k127_96094_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000003628 139.0
XH3_k127_96094_2 Ion channel - - - 0.000000000000000008051 96.0
XH3_k127_96094_3 PFAM TPR repeat-containing protein - - - 0.0000000001454 70.0