Overview

ID MAG04476
Name YHH1_bin.42
Sample SMP0121
Taxonomy
Kingdom Archaea
Phylum Nanobdellota
Class Nanobdellia
Order Woesearchaeales
Family SM23-78
Genus SM23-78
Species
Assembly information
Completeness (%) 61.02
Contamination (%) 0.51
GC content (%) 39.0
N50 (bp) 4,104
Genome size (bp) 810,444

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes659

Gene name Description KEGG GOs EC E-value Score Sequence
YHH1_k127_10012156_0 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000005905 240.0
YHH1_k127_10012156_1 ATPase associated with various cellular activities AAA_5 K03405 - 6.6.1.1 0.0000000000000000000000000000000000009927 153.0
YHH1_k127_10012156_2 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000001452 115.0
YHH1_k127_10012156_3 von Willebrand factor, type A - - - 0.00000149 60.0
YHH1_k127_10012156_4 Peptidase_C39 like family - - - 0.000003595 56.0
YHH1_k127_10131085_0 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000006766 211.0
YHH1_k127_10131085_1 Belongs to the DNase I family K11994,K11995 GO:0000737,GO:0001775,GO:0001910,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002673,GO:0002682,GO:0002697,GO:0002703,GO:0002886,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0006139,GO:0006259,GO:0006308,GO:0006309,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006955,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009987,GO:0010623,GO:0012501,GO:0012505,GO:0016043,GO:0016787,GO:0016788,GO:0019439,GO:0022411,GO:0030154,GO:0030262,GO:0031341,GO:0031347,GO:0032101,GO:0032502,GO:0034641,GO:0034655,GO:0036230,GO:0042119,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046483,GO:0046700,GO:0046872,GO:0048468,GO:0048583,GO:0048856,GO:0048869,GO:0050727,GO:0050789,GO:0050896,GO:0065007,GO:0070948,GO:0071704,GO:0071840,GO:0080134,GO:0090304,GO:0090305,GO:0097159,GO:0097194,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.21.1 0.000000000000000000000000000000003261 139.0
YHH1_k127_10150508_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
YHH1_k127_10150508_1 AraC-like ligand binding domain - - - 0.00000003136 59.0
YHH1_k127_10210319_0 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000002271 228.0
YHH1_k127_10210319_1 Functions in trans to edit the amino acid moiety from K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000002852 219.0
YHH1_k127_10210319_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000002542 142.0
YHH1_k127_10210319_3 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000003982 126.0
YHH1_k127_10295748_0 Metallo-peptidase family M12B Reprolysin-like - - - 0.00007506 54.0
YHH1_k127_10295748_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0002616 54.0
YHH1_k127_10306776_0 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 368.0
YHH1_k127_10306776_1 DNA-directed RNA polymerase, subunit E K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000816 181.0
YHH1_k127_10306776_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000001221 168.0
YHH1_k127_10306776_3 Fcf1 K07158 - - 0.0000000000000003578 83.0
YHH1_k127_10306776_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000233 77.0
YHH1_k127_10306776_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000004379 64.0
YHH1_k127_10306776_6 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000006403 64.0
YHH1_k127_10306776_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00002869 48.0
YHH1_k127_10309603_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 359.0
YHH1_k127_10309603_1 gluconolactonase activity K01053,K01179,K07214,K12287 - 3.1.1.17,3.2.1.4 0.000000000000000006251 96.0
YHH1_k127_10385053_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 397.0
YHH1_k127_10385053_1 Enolase, N-terminal domain K01689 GO:0000015,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003810,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005773,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009277,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009897,GO:0009898,GO:0009986,GO:0009987,GO:0010033,GO:0015976,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016746,GO:0016755,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019863,GO:0019865,GO:0030193,GO:0030195,GO:0030312,GO:0030445,GO:0030446,GO:0030447,GO:0030984,GO:0030985,GO:0031012,GO:0031347,GO:0031349,GO:0032101,GO:0032102,GO:0032787,GO:0032889,GO:0032991,GO:0033043,GO:0033554,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035821,GO:0036180,GO:0040007,GO:0042221,GO:0042730,GO:0042866,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044003,GO:0044088,GO:0044182,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044409,GO:0044416,GO:0044419,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044459,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046677,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0050896,GO:0051128,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051828,GO:0052031,GO:0052173,GO:0052200,GO:0052251,GO:0052255,GO:0052509,GO:0052510,GO:0055086,GO:0055114,GO:0061041,GO:0061045,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0062039,GO:0062040,GO:0065007,GO:0065008,GO:0070887,GO:0071214,GO:0071236,GO:0071310,GO:0071396,GO:0071470,GO:0071554,GO:0071704,GO:0071852,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0075136,GO:0080134,GO:0090407,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:0098552,GO:0098562,GO:0104004,GO:0140096,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1901701,GO:1902494,GO:1903034,GO:1903035 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 313.0
YHH1_k127_10409750_0 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000000000000000000000000000000000004283 192.0
YHH1_k127_10409750_1 Radical SAM superfamily - - - 0.000000000000000000000000000000004084 141.0
YHH1_k127_10476893_0 Transglutaminase-like - - - 0.0000000000000003194 93.0
YHH1_k127_10476893_1 transcription regulator activity - - - 0.00001148 53.0
YHH1_k127_10574253_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001103 256.0
YHH1_k127_10692117_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000003362 188.0
YHH1_k127_10692117_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000003328 178.0
YHH1_k127_10692117_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001875 118.0
YHH1_k127_10692117_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000001232 91.0
YHH1_k127_10692117_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000002752 74.0
YHH1_k127_10692117_5 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000000006864 63.0
YHH1_k127_10730061_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.88e-277 876.0
YHH1_k127_10730061_1 Uncharacterised protein family UPF0052 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 304.0
YHH1_k127_10730061_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000001898 167.0
YHH1_k127_10730061_3 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000001872 164.0
YHH1_k127_10730061_4 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000001625 144.0
YHH1_k127_10730061_5 haloacid dehalogenase K07025 - - 0.0000000000000000000000121 108.0
YHH1_k127_10730061_6 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000008274 89.0
YHH1_k127_10730061_7 Ferredoxin K05337 - - 0.00000000000005675 74.0
YHH1_k127_10730061_8 Domain of unknown function (DUF1858) - - - 0.0000000000001398 74.0
YHH1_k127_10730061_9 Transcriptional regulator - - - 0.0000002526 55.0
YHH1_k127_10752445_1 EamA-like transporter family - - - 0.0000000000000000000008431 102.0
YHH1_k127_10752445_2 Gamma interferon inducible lysosomal thiol reductase (GILT) - - - 0.00000000000009136 85.0
YHH1_k127_10752445_3 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000007037 64.0
YHH1_k127_10752445_4 HupF/HypC family K04653 - - 0.0001326 51.0
YHH1_k127_10764813_0 Stage II sporulation protein - GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00001984 57.0
YHH1_k127_108637_0 PFAM beta-lactamase domain protein K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 334.0
YHH1_k127_108637_1 AI-2E family transporter - - - 0.000000000000000000000000000007626 132.0
YHH1_k127_108637_2 Psort location Periplasmic, score K09807 - - 0.00000000000000000368 93.0
YHH1_k127_108637_3 UPF0056 membrane protein K05595 - - 0.0000000000001296 76.0
YHH1_k127_10927261_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 427.0
YHH1_k127_10927261_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000576 228.0
YHH1_k127_10927261_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0001929 48.0
YHH1_k127_10946530_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 244.0
YHH1_k127_10946530_1 COG0477 Permeases of the major facilitator superfamily K08153,K19578 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0005501 52.0
YHH1_k127_10947637_0 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000001305 174.0
YHH1_k127_10947637_1 Archaeal Nre, N-terminal - - - 0.000000000000000000002057 97.0
YHH1_k127_10947637_2 PFAM peptidase M50 - - - 0.00000000000001123 78.0
YHH1_k127_10947637_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0004646 47.0
YHH1_k127_10969052_0 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000008285 93.0
YHH1_k127_10969052_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001457 90.0
YHH1_k127_10969052_2 Ribosomal_L31e K02910 - - 0.0000008305 58.0
YHH1_k127_10983184_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 556.0
YHH1_k127_10983184_1 Receptor family ligand binding region K01999 - - 0.00000000000000001755 94.0
YHH1_k127_10983184_2 Transcriptional regulator - - - 0.0000006592 60.0
YHH1_k127_1155819_0 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002213 257.0
YHH1_k127_1155819_1 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000001153 59.0
YHH1_k127_1179067_0 endonuclease I - - - 0.0000000000000000000000000006926 125.0
YHH1_k127_1179067_1 Choline/ethanolamine kinase - - - 0.00000000000005609 82.0
YHH1_k127_1252242_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 587.0
YHH1_k127_1355157_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 372.0
YHH1_k127_1355157_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000007728 169.0
YHH1_k127_1355157_2 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000004667 133.0
YHH1_k127_1355157_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000001595 63.0
YHH1_k127_1355157_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000001012 56.0
YHH1_k127_1355157_5 Putative zinc- or iron-chelating domain K06940 - - 0.0000009533 56.0
YHH1_k127_1406792_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 326.0
YHH1_k127_1406792_1 coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000006486 138.0
YHH1_k127_1449876_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000003422 224.0
YHH1_k127_1449876_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000004148 149.0
YHH1_k127_1449876_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000344 102.0
YHH1_k127_1457767_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000524 284.0
YHH1_k127_1457767_1 PFAM Oligosaccharyl transferase STT3 subunit K07151,K21306 - 2.4.99.18,2.4.99.21 0.000000000000000000000000000000000000006725 164.0
YHH1_k127_1504629_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000001146 254.0
YHH1_k127_1504629_1 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002629 177.0
YHH1_k127_1504629_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000001227 72.0
YHH1_k127_1504629_3 Signal peptidase K13280 - 3.4.21.89 0.00000003441 62.0
YHH1_k127_1571559_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 366.0
YHH1_k127_1571559_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000005436 151.0
YHH1_k127_1633226_0 membrane-associated protein domain - - - 0.0000001424 58.0
YHH1_k127_1635025_0 Beta-Casp domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 338.0
YHH1_k127_1635025_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family K11434 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006325,GO:0006355,GO:0006357,GO:0006403,GO:0006405,GO:0006406,GO:0006464,GO:0006479,GO:0006611,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008469,GO:0008757,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0015031,GO:0015833,GO:0015931,GO:0016043,GO:0016273,GO:0016274,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018193,GO:0018195,GO:0018216,GO:0019219,GO:0019222,GO:0019538,GO:0019919,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031503,GO:0031554,GO:0032259,GO:0032784,GO:0032786,GO:0032968,GO:0033036,GO:0034243,GO:0034613,GO:0034969,GO:0035241,GO:0035242,GO:0035246,GO:0035247,GO:0036211,GO:0042054,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050657,GO:0050658,GO:0050789,GO:0050794,GO:0051028,GO:0051128,GO:0051129,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051236,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051641,GO:0051649,GO:0060255,GO:0060567,GO:0065007,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0080090,GO:0140096,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.319 0.0000000001216 69.0
YHH1_k127_1636800_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K01179 - 3.2.1.4 0.00000000469 71.0
YHH1_k127_1647521_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 377.0
YHH1_k127_1647521_1 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 362.0
YHH1_k127_1647521_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000002534 198.0
YHH1_k127_1647521_3 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000003397 91.0
YHH1_k127_1647521_4 Ribosomal RNA methyltransferase (FmrO) K18845 - 2.1.1.179 0.0000000000005054 79.0
YHH1_k127_1687989_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000216 243.0
YHH1_k127_1687989_1 Belongs to the peptidase S16 family K06870 - - 0.00000000000000000000000000000000000000000000003016 190.0
YHH1_k127_1687989_2 RIO1 family K08851 - 2.7.11.1 0.000000000000000000000000000004211 129.0
YHH1_k127_1687989_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000003988 61.0
YHH1_k127_1715733_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002066 238.0
YHH1_k127_1715733_1 PFAM Haloacid dehalogenase domain protein hydrolase K01091 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.00000000000004755 80.0
YHH1_k127_1715733_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00008506 49.0
YHH1_k127_1715733_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0009913 49.0
YHH1_k127_1790857_0 PRC-barrel domain - - - 0.000001816 53.0
YHH1_k127_1858588_0 FMN binding - - - 0.000003158 55.0
YHH1_k127_1861398_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 469.0
YHH1_k127_1861398_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000004406 132.0
YHH1_k127_1861398_2 DnaB-like helicase C terminal domain - - - 0.00000000000005019 76.0
YHH1_k127_1924801_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000352 173.0
YHH1_k127_1924801_1 Psort location Cytoplasmic, score K02503 - - 0.00000000000000000000002493 109.0
YHH1_k127_1924801_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000001736 66.0
YHH1_k127_1935391_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000001896 216.0
YHH1_k127_1935391_1 PFAM Peptidase M29, aminopeptidase II K19689 - - 0.0000005246 63.0
YHH1_k127_1956310_0 PFAM DNA polymerase, beta domain protein region K07076 - - 0.00000005536 64.0
YHH1_k127_203558_0 - - - - 0.000001603 59.0
YHH1_k127_203558_1 Sulfotransferase family - - - 0.0003768 50.0
YHH1_k127_2063606_0 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000000000001208 115.0
YHH1_k127_2063606_1 Peptidase family M9 N-terminal - - - 0.000001982 60.0
YHH1_k127_2071962_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000003041 229.0
YHH1_k127_2071962_1 Phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000001413 220.0
YHH1_k127_2093222_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001708 253.0
YHH1_k127_2093222_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000203 139.0
YHH1_k127_2093222_2 peptidase activity, acting on L-amino acid peptides - - - 0.00003366 57.0
YHH1_k127_2147482_0 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000000000000000002846 128.0
YHH1_k127_2147482_1 Acetyltransferase (GNAT) family - - - 0.00001129 53.0
YHH1_k127_2147482_2 PFAM Xylose isomerase - - - 0.0006884 52.0
YHH1_k127_2161176_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000002401 231.0
YHH1_k127_2161176_1 Phosphate uptake regulator - - - 0.0000000000393 74.0
YHH1_k127_2161176_2 Psort location Periplasmic, score K01999 - - 0.0000000004152 66.0
YHH1_k127_2161176_3 Aminoglycoside phosphotransferase - - - 0.0003104 53.0
YHH1_k127_2203178_0 Belongs to the ParB family K03497 - - 0.00000000000001513 87.0
YHH1_k127_2203178_1 Belongs to the ParB family K03497 - - 0.00000000002084 77.0
YHH1_k127_2235452_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000001033 196.0
YHH1_k127_236996_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K00806,K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.89 0.0000000000000000000000000000000000000000000000001142 186.0
YHH1_k127_236996_1 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000006326 138.0
YHH1_k127_2477959_0 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000002281 53.0
YHH1_k127_2477959_1 SMART AAA ATPase K06915 - - 0.00008907 57.0
YHH1_k127_2500265_0 Chitinase class I K03791 - - 0.00000000000000000000000009146 121.0
YHH1_k127_2500265_1 Membrane proteins related to metalloendopeptidases K21471 - - 0.00000000000004573 87.0
YHH1_k127_2548612_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 368.0
YHH1_k127_2548612_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002215 256.0
YHH1_k127_2548612_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000001959 66.0
YHH1_k127_2548612_3 diacylglycerol kinase, catalytic - - - 0.00002129 53.0
YHH1_k127_267886_0 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
YHH1_k127_267886_1 PFAM Methyltransferase type 11 - - - 0.000000000004137 74.0
YHH1_k127_270329_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.873e-250 795.0
YHH1_k127_270329_1 Belongs to the MCM family K10726 - - 0.000000000000000000000000000000002033 145.0
YHH1_k127_270329_2 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.000000000000000001305 90.0
YHH1_k127_270329_3 membrane-associated protein domain - - - 0.000000003116 64.0
YHH1_k127_2712456_0 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008392 264.0
YHH1_k127_2712456_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000004841 216.0
YHH1_k127_2712456_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000003655 166.0
YHH1_k127_2712456_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000005827 151.0
YHH1_k127_2712456_4 Transcriptional regulator, TrmB - - - 0.000000000000000009543 93.0
YHH1_k127_2712456_5 Archaeal transcriptional regulator TrmB - - - 0.0006451 50.0
YHH1_k127_3101826_0 Ion channel - - - 0.0000000000005776 74.0
YHH1_k127_3206654_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000004615 172.0
YHH1_k127_3206654_1 Sugar-specific transcriptional regulator TrmB - - - 0.00002309 55.0
YHH1_k127_3210767_0 ATPase family associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 296.0
YHH1_k127_3210767_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000008274 115.0
YHH1_k127_3210767_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000933 94.0
YHH1_k127_3210767_3 DNA polymerase beta - - - 0.0000000004742 66.0
YHH1_k127_3210767_4 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000002527 58.0
YHH1_k127_322250_0 low molecular weight K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000008637 82.0
YHH1_k127_322250_1 TPM domain K06872 - - 0.00000000002863 68.0
YHH1_k127_322250_2 Xylose isomerase domain-containing protein TIM barrel - - - 0.0000007023 60.0
YHH1_k127_3246992_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 386.0
YHH1_k127_3246992_1 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000711 111.0
YHH1_k127_3246992_2 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000001048 104.0
YHH1_k127_3246992_3 Receptor family ligand binding region - - - 0.0000000000004148 81.0
YHH1_k127_3261595_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002053 253.0
YHH1_k127_3261595_1 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
YHH1_k127_3261595_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000001813 217.0
YHH1_k127_3261595_3 nitroreductase - - - 0.000000000000000000000000000000000000002371 156.0
YHH1_k127_3261595_4 Starch synthase catalytic domain K00703 - 2.4.1.21 0.00001349 47.0
YHH1_k127_3268953_0 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000007735 194.0
YHH1_k127_3272668_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 334.0
YHH1_k127_3272668_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 300.0
YHH1_k127_328166_0 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
YHH1_k127_328166_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000007972 143.0
YHH1_k127_328166_2 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000006303 128.0
YHH1_k127_3285482_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000002284 182.0
YHH1_k127_3285482_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000002291 136.0
YHH1_k127_3285482_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000001912 126.0
YHH1_k127_3285482_3 Radical SAM K22227 - - 0.000000000000000000000000006797 115.0
YHH1_k127_3285482_4 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.0000000000000000000003725 99.0
YHH1_k127_3285482_5 Predicted membrane protein (DUF2177) - - - 0.0000000000000001794 83.0
YHH1_k127_3285482_6 Transcriptional regulator K03718 - - 0.000000002868 68.0
YHH1_k127_346293_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 409.0
YHH1_k127_346293_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000009965 237.0
YHH1_k127_346293_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.000000000000000000000000004673 119.0
YHH1_k127_346293_3 nuclease activity K06218 - - 0.000003361 53.0
YHH1_k127_3497541_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 327.0
YHH1_k127_3614404_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002804 280.0
YHH1_k127_3614404_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000003115 70.0
YHH1_k127_3625538_0 glutamyl-prolyl-tRNA synthetase K01885,K14163 GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004818,GO:0004827,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006424,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010876,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0016043,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0019899,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032868,GO:0032869,GO:0032870,GO:0032991,GO:0033036,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034641,GO:0034645,GO:0034660,GO:0035613,GO:0042221,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044539,GO:0045087,GO:0046483,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071345,GO:0071346,GO:0071375,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097452,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1990904,GO:2000112,GO:2000113 6.1.1.15,6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 527.0
YHH1_k127_3625538_1 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000007476 100.0
YHH1_k127_3625538_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000588 68.0
YHH1_k127_3656622_0 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 324.0
YHH1_k127_3656622_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000001294 124.0
YHH1_k127_3656622_2 phosphorelay signal transduction system K07714 - - 0.00000001531 66.0
YHH1_k127_3684236_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000249 147.0
YHH1_k127_3684236_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000003636 76.0
YHH1_k127_3707327_0 Glycosyl hydrolases family 15 K07190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002925 278.0
YHH1_k127_3707327_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000002436 59.0
YHH1_k127_3763148_0 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
YHH1_k127_3763148_1 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000009617 224.0
YHH1_k127_3763148_2 dephospho-CoA kinase activity - - - 0.0000000000000000000000000000000000001314 147.0
YHH1_k127_3763148_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000002284 102.0
YHH1_k127_3763148_4 Peptidase S24-like K13280 - 3.4.21.89 0.000000001042 68.0
YHH1_k127_3763148_5 COG0500 SAM-dependent methyltransferases - - - 0.000000007452 64.0
YHH1_k127_3763148_6 Belongs to the UPF0235 family K09131 - - 0.0000008475 53.0
YHH1_k127_3795388_0 type II secretion system K12510 - - 0.0007574 51.0
YHH1_k127_3963639_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 325.0
YHH1_k127_3963639_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
YHH1_k127_3963639_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000001672 83.0
YHH1_k127_3991022_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 526.0
YHH1_k127_3991022_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000004429 177.0
YHH1_k127_3991022_2 Protein conserved in bacteria - - - 0.00000000000000000000000001442 121.0
YHH1_k127_3991022_3 transferase activity, transferring glycosyl groups K16148 - 2.4.1.342 0.000000000000000000001984 105.0
YHH1_k127_3991022_4 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000002515 53.0
YHH1_k127_4000673_0 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.0000000000000000000000000000000000004148 151.0
YHH1_k127_4000673_1 - - - - 0.0000000006479 63.0
YHH1_k127_4050157_0 replication factor A K07466 - - 0.000000000000000000000000000000000000000001598 171.0
YHH1_k127_4050157_1 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0031668,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0000000001331 68.0
YHH1_k127_4050157_2 CARDB - - - 0.0005631 49.0
YHH1_k127_4128112_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 392.0
YHH1_k127_4196193_0 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000002075 74.0
YHH1_k127_4196193_1 Domain of unknown function (DUF2341) - - - 0.00009557 54.0
YHH1_k127_4210567_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005922 272.0
YHH1_k127_4210567_1 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000001168 128.0
YHH1_k127_4324077_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 331.0
YHH1_k127_4324077_1 deoxyhypusine synthase activity K00809,K01930,K19721 GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006417,GO:0006464,GO:0006518,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008216,GO:0008284,GO:0008612,GO:0009056,GO:0009058,GO:0009059,GO:0009308,GO:0009310,GO:0009553,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0022407,GO:0022409,GO:0022607,GO:0030155,GO:0031323,GO:0031326,GO:0032268,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033500,GO:0034038,GO:0034248,GO:0034641,GO:0034645,GO:0036211,GO:0042102,GO:0042127,GO:0042129,GO:0042402,GO:0042592,GO:0042593,GO:0042802,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045785,GO:0046203,GO:0048229,GO:0048518,GO:0048522,GO:0048856,GO:0048878,GO:0050670,GO:0050671,GO:0050789,GO:0050794,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0051171,GO:0051246,GO:0051249,GO:0051251,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051604,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070663,GO:0070665,GO:0071704,GO:0071840,GO:0080090,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903037,GO:1903039,GO:2000112,GO:2000765 2.5.1.46,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 318.0
YHH1_k127_4324077_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.000000004617 62.0
YHH1_k127_4336485_0 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000000000003858 119.0
YHH1_k127_4336485_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000006666 112.0
YHH1_k127_4418842_0 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000399 252.0
YHH1_k127_4418842_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000002018 235.0
YHH1_k127_4418842_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.000000000000000000000000000000000000000000008428 171.0
YHH1_k127_4479679_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000006306 211.0
YHH1_k127_4479679_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000004269 208.0
YHH1_k127_4655658_0 Tyrosyl-tRNA synthetase K01866 GO:0000049,GO:0001664,GO:0002682,GO:0002685,GO:0002688,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004831,GO:0005102,GO:0005126,GO:0005153,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0006915,GO:0006935,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009605,GO:0009966,GO:0009987,GO:0010467,GO:0010469,GO:0010646,GO:0010758,GO:0012501,GO:0016070,GO:0016604,GO:0016874,GO:0016875,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0023051,GO:0030334,GO:0030545,GO:0031974,GO:0031981,GO:0032101,GO:0032879,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034660,GO:0040011,GO:0040012,GO:0042056,GO:0042221,GO:0042330,GO:0042379,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045236,GO:0046483,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050918,GO:0050920,GO:0051270,GO:0051716,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1905521,GO:2000145 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 327.0
YHH1_k127_4655658_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000008078 97.0
YHH1_k127_4660382_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000001506 206.0
YHH1_k127_4660382_1 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000006072 154.0
YHH1_k127_4680580_0 - - - - 0.0000000000000000000000000000000001513 144.0
YHH1_k127_4680580_1 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000003091 120.0
YHH1_k127_4680580_2 glutamate--cysteine ligase - - - 0.0000000000002715 82.0
YHH1_k127_4680580_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000002777 79.0
YHH1_k127_4680580_4 of the drug metabolite transporter (DMT) superfamily - - - 0.0007743 49.0
YHH1_k127_4684924_0 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000003865 151.0
YHH1_k127_4696563_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000011 206.0
YHH1_k127_4696563_1 Protein of unknown function (DUF1460) - - - 0.000000000000000000009136 102.0
YHH1_k127_4696563_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000002064 63.0
YHH1_k127_4711840_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001013 271.0
YHH1_k127_4711840_1 Forms part of the polypeptide exit tunnel K02930 - - 0.00000000000000000000000000000000000000000005957 168.0
YHH1_k127_4840958_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 402.0
YHH1_k127_4840958_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000001001 209.0
YHH1_k127_4840958_2 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000006713 79.0
YHH1_k127_4840958_3 PFAM Diphthamide synthesis DPH2 protein K07561 GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.5.1.108 0.0000000002981 64.0
YHH1_k127_4840958_4 PFAM regulatory protein AsnC Lrp family K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00001982 56.0
YHH1_k127_491317_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
YHH1_k127_491317_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000001255 133.0
YHH1_k127_491317_2 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000000007696 82.0
YHH1_k127_491317_3 - - - - 0.0000002437 56.0
YHH1_k127_491317_4 domain, Protein - - - 0.000006796 55.0
YHH1_k127_5021238_0 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000001205 166.0
YHH1_k127_5021238_1 PAC2 family K07159 - - 0.00000000000000000000000000000000007371 143.0
YHH1_k127_5021238_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000009369 123.0
YHH1_k127_5021238_3 PFAM Ribosomal protein S27E K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000005701 84.0
YHH1_k127_5021238_4 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000002909 51.0
YHH1_k127_5039464_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000003629 212.0
YHH1_k127_5039464_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K00996 - 2.7.8.6 0.0000000000000000001421 100.0
YHH1_k127_505471_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 288.0
YHH1_k127_505471_1 queuine tRNA-ribosyltransferase activity - - - 0.00000000000000000000000000000000000000000000003161 173.0
YHH1_k127_505471_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000004464 168.0
YHH1_k127_505471_3 membrane - - - 0.00000000000000000000000002787 125.0
YHH1_k127_505471_4 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase K04034 - 1.21.98.3 0.00000000000000000003385 94.0
YHH1_k127_505471_5 EamA-like transporter family K12962 - - 0.00000000001945 70.0
YHH1_k127_505471_6 EamA-like transporter family K12962 - - 0.00000000004793 67.0
YHH1_k127_5072734_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000003371 245.0
YHH1_k127_5072734_1 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000003278 67.0
YHH1_k127_5096540_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000001124 142.0
YHH1_k127_5096540_1 DnaB-like helicase C terminal domain - - - 0.000003036 50.0
YHH1_k127_529075_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 376.0
YHH1_k127_529075_1 Tetratricopeptide repeat - - - 0.0002006 48.0
YHH1_k127_529075_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0006314 45.0
YHH1_k127_534419_0 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 280.0
YHH1_k127_534419_1 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000001209 160.0
YHH1_k127_5476791_0 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 320.0
YHH1_k127_5476791_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000006501 193.0
YHH1_k127_5476791_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000001878 118.0
YHH1_k127_5541070_0 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 362.0
YHH1_k127_5541070_1 PFAM Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000001476 60.0
YHH1_k127_562123_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000008431 242.0
YHH1_k127_562123_1 permease - - - 0.000000000000000000000000000000000002694 145.0
YHH1_k127_562123_2 Glycogen debranching enzyme - - - 0.00000001074 62.0
YHH1_k127_5740602_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 406.0
YHH1_k127_5740602_1 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005153 104.0
YHH1_k127_5740602_2 binds to the 23S rRNA K02876 - - 0.0000000003366 65.0
YHH1_k127_5740602_3 Integral membrane protein DUF106 - - - 0.00000006697 63.0
YHH1_k127_5947842_0 Belongs to the peptidase S8 family - - - 0.00000000000000001011 98.0
YHH1_k127_5947842_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000005284 68.0
YHH1_k127_597431_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 515.0
YHH1_k127_597431_1 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 347.0
YHH1_k127_597431_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000006376 254.0
YHH1_k127_597431_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001863 249.0
YHH1_k127_597431_4 Fibronectin-binding A domain protein - - - 0.0000000000000000000000000000000000000000000000000000001883 208.0
YHH1_k127_597431_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000001418 142.0
YHH1_k127_5979148_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 2.577e-223 707.0
YHH1_k127_5979148_1 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 297.0
YHH1_k127_5979148_2 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000002091 165.0
YHH1_k127_5979148_3 Domain of unknown function (DUF1610) K07580 - - 0.000000000000002198 79.0
YHH1_k127_6032189_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 436.0
YHH1_k127_6032189_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
YHH1_k127_6032189_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000004443 104.0
YHH1_k127_6032189_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000001222 96.0
YHH1_k127_6032189_4 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000002741 71.0
YHH1_k127_6100830_0 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000007182 212.0
YHH1_k127_6100830_1 binds to the 23S rRNA K02921 - - 0.00000000000279 70.0
YHH1_k127_6100830_2 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.000000000004137 74.0
YHH1_k127_6100830_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000002181 68.0
YHH1_k127_6100830_4 Belongs to the UPF0147 family K09721 - - 0.0000003329 55.0
YHH1_k127_6100830_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0002316 45.0
YHH1_k127_6100830_6 COG0668 Small-conductance mechanosensitive channel - - - 0.0002984 50.0
YHH1_k127_6107211_0 AP endonuclease family 2 K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 338.0
YHH1_k127_6107211_1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
YHH1_k127_6107211_2 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000003452 119.0
YHH1_k127_6107211_3 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.000004035 51.0
YHH1_k127_6119515_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 367.0
YHH1_k127_6119515_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000003176 144.0
YHH1_k127_6119515_2 protein-(glutamine-N5) methyltransferase activity K00612 - - 0.00000000000000000000004561 109.0
YHH1_k127_6121602_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000001776 181.0
YHH1_k127_6121602_1 Polysaccharide deacetylase - - - 0.00000000000000000003756 101.0
YHH1_k127_6121602_2 Formyl transferase - - - 0.000000000000004778 85.0
YHH1_k127_6144050_0 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000008481 159.0
YHH1_k127_6144050_1 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000002587 106.0
YHH1_k127_6144050_2 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000008609 99.0
YHH1_k127_6144050_3 PFAM helix-turn-helix domain protein K03627 - - 0.00000000000000001339 89.0
YHH1_k127_6144050_5 but it may be involved in stabilization of the trimeric complex - - - 0.0001282 46.0
YHH1_k127_6207033_0 histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 347.0
YHH1_k127_6207033_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 297.0
YHH1_k127_6207033_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000195 185.0
YHH1_k127_6207033_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000001552 180.0
YHH1_k127_6207033_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000667 133.0
YHH1_k127_6207033_5 Participates in transcription termination K02600 - - 0.000000000000000003006 91.0
YHH1_k127_6207033_6 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000004075 55.0
YHH1_k127_6211089_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007918 279.0
YHH1_k127_6211089_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000003119 229.0
YHH1_k127_6211089_10 guanyl-nucleotide exchange factor activity - - - 0.00001048 59.0
YHH1_k127_6211089_2 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000004621 143.0
YHH1_k127_6211089_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000001026 147.0
YHH1_k127_6211089_4 COG1361 S-layer domain - - - 0.000000000000000000004123 107.0
YHH1_k127_6211089_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K00525,K03724 - 1.17.4.1 0.000000005778 65.0
YHH1_k127_6211089_6 protein homooligomerization - - - 0.00000001685 65.0
YHH1_k127_6211089_8 Signal peptidase K13280 - 3.4.21.89 0.0000001443 61.0
YHH1_k127_6211089_9 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001239 52.0
YHH1_k127_6217302_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 590.0
YHH1_k127_6217302_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000006438 231.0
YHH1_k127_6217302_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000006465 204.0
YHH1_k127_6217302_3 Protein of unknown function (DUF1698) - - - 0.00000000000000000000001015 111.0
YHH1_k127_6284163_0 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
YHH1_k127_6284163_1 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000004596 142.0
YHH1_k127_6284163_2 Glycosyl transferase 4-like K19422 - - 0.000000000000000000000000005311 124.0
YHH1_k127_6284163_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000000000309 100.0
YHH1_k127_6284163_4 UDP-N-acetylglucosamine 2-epimerase - - - 0.000000000000001364 91.0
YHH1_k127_6284163_5 PFAM Oligosaccharyl transferase STT3 subunit K21306 - 2.4.99.21 0.0005459 51.0
YHH1_k127_63726_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005965 288.0
YHH1_k127_63726_1 Pyrimidine dimer DNA glycosylase K01161 - 3.1.25.1 0.00000000000000000007686 94.0
YHH1_k127_63726_2 SMART Cystathionine beta-synthase, core - - - 0.0000000000000000004214 98.0
YHH1_k127_63726_3 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000375 81.0
YHH1_k127_63726_4 RNA binding K07581 - - 0.00000000001098 72.0
YHH1_k127_6402453_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000001464 252.0
YHH1_k127_6402453_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000001206 170.0
YHH1_k127_6402453_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000003057 156.0
YHH1_k127_6402453_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000002068 83.0
YHH1_k127_6441485_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000003285 120.0
YHH1_k127_6441485_1 amine dehydrogenase activity - - - 0.000000000001065 78.0
YHH1_k127_6478163_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.61e-221 709.0
YHH1_k127_6478163_1 MgtC family K07507 - - 0.0000003519 58.0
YHH1_k127_6482184_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000001335 258.0
YHH1_k127_6517180_0 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 530.0
YHH1_k127_6517180_1 synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 270.0
YHH1_k127_6517180_2 Aldo/keto reductase family - - - 0.00005332 45.0
YHH1_k127_6538640_0 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000006971 156.0
YHH1_k127_6538640_1 Conserved hypothetical protein 95 K07579 - - 0.000000000000002613 80.0
YHH1_k127_6538640_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000001843 69.0
YHH1_k127_6750032_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 358.0
YHH1_k127_6750032_1 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000004499 104.0
YHH1_k127_6750032_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000003791 90.0
YHH1_k127_6750032_3 Pkd domain containing protein - - - 0.00000000000000002802 96.0
YHH1_k127_6750032_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000005745 66.0
YHH1_k127_6750032_5 PFAM Chloroplast import component protein (Tic20) - - - 0.0000000003752 66.0
YHH1_k127_6750032_6 alpha-L-arabinofuranosidase - - - 0.0002172 54.0
YHH1_k127_6787736_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002454 256.0
YHH1_k127_6787736_1 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000001435 196.0
YHH1_k127_6787736_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000001001 72.0
YHH1_k127_6836715_0 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000001592 100.0
YHH1_k127_6836715_1 Acetyltransferase (GNAT) family - - - 0.00004764 52.0
YHH1_k127_6905097_0 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 469.0
YHH1_k127_6905097_1 Polysaccharide biosynthesis protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000003615 206.0
YHH1_k127_6905097_2 transferase K00997 - 2.7.8.7 0.0000000000000000007736 92.0
YHH1_k127_6905097_3 inositol 2-dehydrogenase activity K18106 - - 0.00000000000000001892 83.0
YHH1_k127_6958712_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
YHH1_k127_6958712_1 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 0.0000000000000000000000000000000000000000001103 165.0
YHH1_k127_695920_0 MiaB-like tRNA modifying enzyme, archaeal-type - - - 0.000000000000000000000000000000000000000000000000003466 189.0
YHH1_k127_695920_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000007977 181.0
YHH1_k127_695920_2 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.0000000000000001693 90.0
YHH1_k127_6984430_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 339.0
YHH1_k127_6984430_1 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000004953 108.0
YHH1_k127_6984430_2 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000002765 93.0
YHH1_k127_6984430_3 helix_turn_helix ASNC type K03719 - - 0.00007258 52.0
YHH1_k127_6994274_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 482.0
YHH1_k127_6994274_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 415.0
YHH1_k127_6994274_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
YHH1_k127_6994274_3 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 314.0
YHH1_k127_6994274_4 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
YHH1_k127_6994274_5 Sulfite reductase Subunit B K16951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007317 251.0
YHH1_k127_6994274_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000004069 200.0
YHH1_k127_6994274_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000002664 124.0
YHH1_k127_6994274_8 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000003802 76.0
YHH1_k127_7013290_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000001914 201.0
YHH1_k127_7013290_1 binds to the 23S rRNA K02929 - - 0.000000000000001168 80.0
YHH1_k127_7013290_2 Transglycosylase SLT domain - - - 0.00003575 53.0
YHH1_k127_710337_0 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 294.0
YHH1_k127_710337_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000008305 128.0
YHH1_k127_7173255_0 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 381.0
YHH1_k127_7173255_1 PFAM RIO-like kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001423 205.0
YHH1_k127_7173255_2 SMART KH domain protein K06961 - - 0.00000000000000000000000000000000000000000006038 167.0
YHH1_k127_7173255_3 cell redox homeostasis - - - 0.000447 42.0
YHH1_k127_7182170_0 HAD-superfamily phosphatase, subfamily IIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 539.0
YHH1_k127_7182170_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 401.0
YHH1_k127_7182170_2 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000003276 204.0
YHH1_k127_7182170_3 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000002916 150.0
YHH1_k127_7182170_4 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000008457 118.0
YHH1_k127_7182170_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000002119 72.0
YHH1_k127_7255023_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000006922 123.0
YHH1_k127_7255023_1 PFAM Cupin domain K05916 - 1.14.12.17 0.0000000000000000000006712 98.0
YHH1_k127_7255023_2 MarC family integral membrane protein - - - 0.000000000000001082 83.0
YHH1_k127_7307909_0 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000002547 158.0
YHH1_k127_7307909_1 Glycosyl transferase family 2 - - - 0.00000005474 59.0
YHH1_k127_7307909_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00001082 53.0
YHH1_k127_7307909_3 Glycosyltransferase, group 1 family protein - - - 0.0002743 47.0
YHH1_k127_7346484_0 COG3387 Glucoamylase and related glycosyl K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 536.0
YHH1_k127_7350325_0 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007765 282.0
YHH1_k127_7350325_1 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000004307 103.0
YHH1_k127_7350325_2 mRNA decay K07562 - - 0.000000000000000004231 92.0
YHH1_k127_745460_0 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 441.0
YHH1_k127_745460_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 437.0
YHH1_k127_745460_2 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 381.0
YHH1_k127_745460_3 COG3980 Spore coat polysaccharide biosynthesis protein - - - 0.0000000000000105 81.0
YHH1_k127_745460_4 UDP-N-acetylglucosamine 4,6-dehydratase - - - 0.00009953 48.0
YHH1_k127_7468098_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 298.0
YHH1_k127_7468098_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000003398 216.0
YHH1_k127_7468098_2 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000001112 151.0
YHH1_k127_7468098_3 Transmembrane amino acid transporter protein - - - 0.0000000000000000000000000000000003305 145.0
YHH1_k127_7468098_4 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.00000000000000000000000000002418 122.0
YHH1_k127_7468098_5 membrane transporter protein K07090 - - 0.000000000000000000004189 102.0
YHH1_k127_7468098_6 Centromere kinetochore component CENP-T histone fold - - - 0.000000003998 60.0
YHH1_k127_7468098_7 spore germination K08978 - - 0.000000005855 66.0
YHH1_k127_7630655_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.117e-220 711.0
YHH1_k127_7630655_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000001473 124.0
YHH1_k127_7630655_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000002993 91.0
YHH1_k127_7630655_3 - - - - 0.00000001459 61.0
YHH1_k127_7630655_4 Sugar-specific transcriptional regulator TrmB - - - 0.000002965 57.0
YHH1_k127_7800216_0 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 287.0
YHH1_k127_7800216_1 Desulfoferrodoxin, N-terminal domain K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000004375 210.0
YHH1_k127_7800216_2 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.00000000000000000000000000000000000000000000008588 177.0
YHH1_k127_7800216_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000001559 88.0
YHH1_k127_7800216_4 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.00000000522 61.0
YHH1_k127_7800216_5 - - - - 0.00000002479 57.0
YHH1_k127_7838108_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01531,K01535 - 3.6.3.2,3.6.3.6 4.04e-245 782.0
YHH1_k127_7838108_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 534.0
YHH1_k127_7838108_2 Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan K00693 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 407.0
YHH1_k127_7838108_3 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 317.0
YHH1_k127_7838108_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000001162 72.0
YHH1_k127_7918910_0 PFAM Mov34 MPN PAD-1 - - - 0.0000000000000000000000000002286 119.0
YHH1_k127_7918910_1 Methyltransferase domain - - - 0.00000000000001721 79.0
YHH1_k127_7918910_2 Radical SAM - - - 0.00000004452 56.0
YHH1_k127_7950188_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 352.0
YHH1_k127_7950188_1 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
YHH1_k127_7950188_2 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
YHH1_k127_7952506_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000001337 251.0
YHH1_k127_7952506_1 Involved in protein export K03074 - - 0.00000000000000000000000000000000001399 143.0
YHH1_k127_7954504_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
YHH1_k127_7954504_1 exosome subunit K14574 - - 0.000000000000000008435 87.0
YHH1_k127_7954504_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000003129 65.0
YHH1_k127_7957173_0 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
YHH1_k127_7957173_1 Cold-Shock Protein K03704 - - 0.000002738 50.0
YHH1_k127_8083924_0 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 256.0
YHH1_k127_8135750_0 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 372.0
YHH1_k127_8206480_0 BRO family, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
YHH1_k127_8206480_1 Domain of unknown function (DUF4082) - - - 0.0000004797 61.0
YHH1_k127_8223429_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 615.0
YHH1_k127_8223429_1 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.000000000000000000000000000003859 127.0
YHH1_k127_8240744_0 Mcm family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 529.0
YHH1_k127_8240744_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000001266 187.0
YHH1_k127_8240744_2 helicase activity - - - 0.000000000001575 76.0
YHH1_k127_8240744_3 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000001655 67.0
YHH1_k127_8240744_4 Stage II sporulation protein M K06384 - - 0.0000258 54.0
YHH1_k127_8248838_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000002275 230.0
YHH1_k127_8248838_1 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000005206 199.0
YHH1_k127_8248838_2 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000002264 91.0
YHH1_k127_8248838_3 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.000000000004137 74.0
YHH1_k127_8248838_4 spore germination K08978 - - 0.0001056 46.0
YHH1_k127_8271499_0 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 437.0
YHH1_k127_8271499_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000008208 239.0
YHH1_k127_8271499_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000216 231.0
YHH1_k127_8271499_3 fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000001381 198.0
YHH1_k127_8271499_4 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000003024 181.0
YHH1_k127_828315_0 PAC2 family K06869 - - 0.0000000000000000000004032 104.0
YHH1_k127_828315_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00006493 48.0
YHH1_k127_8335301_0 Zn_pept K05996 - 3.4.17.18 0.000000000000006341 89.0
YHH1_k127_8335301_1 SdrD B-like domain - - - 0.00000000000002526 87.0
YHH1_k127_8335301_2 COG1520 FOG WD40-like repeat - - - 0.0006263 50.0
YHH1_k127_8370389_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000002535 233.0
YHH1_k127_8370389_1 Peptidase M50 - - - 0.00000008147 61.0
YHH1_k127_8370389_2 Required for chromosome condensation and partitioning - - - 0.0001721 53.0
YHH1_k127_8376266_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 570.0
YHH1_k127_8376266_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 355.0
YHH1_k127_8376266_2 PHP domain K07053 - 3.1.3.97 0.0003153 51.0
YHH1_k127_8426146_0 domain protein K01179,K01342,K01406,K07004,K12287,K14194,K15125,K20276 - 3.2.1.4,3.4.21.62,3.4.24.40 0.0000000002113 75.0
YHH1_k127_8426146_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00007081 56.0
YHH1_k127_8587441_0 reductase - - - 0.000000000007065 74.0
YHH1_k127_8587441_1 Lipase (class 2) - - - 0.0000000001176 72.0
YHH1_k127_8587441_2 nucleotide metabolic process - - - 0.0000000002139 70.0
YHH1_k127_8587441_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000006709 55.0
YHH1_k127_859212_0 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000006463 113.0
YHH1_k127_859212_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000001228 76.0
YHH1_k127_859212_2 - - - - 0.0000003305 61.0
YHH1_k127_859212_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.39 0.0006609 49.0
YHH1_k127_8619927_0 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000003392 213.0
YHH1_k127_8619927_1 PFAM zinc iron permease K16267 - - 0.00000000000000000000004446 102.0
YHH1_k127_8682607_0 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000004745 111.0
YHH1_k127_8682607_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000001663 96.0
YHH1_k127_8758360_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 364.0
YHH1_k127_8758360_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 286.0
YHH1_k127_8758360_2 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
YHH1_k127_8758360_3 Transcriptional regulator, TrmB - - - 0.0000000000000000000000007745 111.0
YHH1_k127_8758360_4 Sodium:solute symporter family K03307 - - 0.0000000000000000001468 102.0
YHH1_k127_8758360_5 Transcriptional regulator, TrmB - - - 0.000002104 50.0
YHH1_k127_8758360_6 Bacterial PH domain K09167 - - 0.0005538 45.0
YHH1_k127_8760573_0 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 7.81e-198 629.0
YHH1_k127_8760573_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 408.0
YHH1_k127_8760573_10 Putative Fe-S cluster - - - 0.0000009008 53.0
YHH1_k127_8760573_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000643 237.0
YHH1_k127_8760573_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000006051 195.0
YHH1_k127_8760573_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000001574 121.0
YHH1_k127_8760573_5 Kazal-type proteinase inhibitor 1 - - - 0.000000000000000000000001855 116.0
YHH1_k127_8760573_6 CutA1 divalent ion tolerance protein K03926 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000005177 102.0
YHH1_k127_8760573_7 Helix-turn-helix domain - - - 0.00000000000000000001054 101.0
YHH1_k127_8760573_8 PFAM Nucleotide-binding protein, PIN domain - - - 0.00000000000000000001154 97.0
YHH1_k127_8827228_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 301.0
YHH1_k127_8827228_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000001043 188.0
YHH1_k127_8827228_2 domain protein K01421 - - 0.000001323 60.0
YHH1_k127_8869398_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 465.0
YHH1_k127_8881066_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 446.0
YHH1_k127_8881066_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 280.0
YHH1_k127_8881066_2 AsnC-type helix-turn-helix domain K15782 - - 0.000000002228 68.0
YHH1_k127_8930191_0 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 335.0
YHH1_k127_8930191_1 binds to the 23S rRNA K02921 - - 0.0000000000000211 77.0
YHH1_k127_8946975_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 589.0
YHH1_k127_8951307_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001439 220.0
YHH1_k127_8951307_1 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000002706 163.0
YHH1_k127_8951307_2 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000226 117.0
YHH1_k127_8951307_3 Binds to the 23S rRNA K02885 - - 0.00000002064 58.0
YHH1_k127_8951307_4 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0001621 46.0
YHH1_k127_8956116_0 Aldose 1-epimerase - - - 0.000000000000000000000002301 115.0
YHH1_k127_8962089_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000002031 192.0
YHH1_k127_8962089_1 - - - - 0.00000000000001401 76.0
YHH1_k127_8975985_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000001708 87.0
YHH1_k127_8975985_1 ATP binding binding kinase protein kinase protein serine threonine kinase K17545 GO:0000003,GO:0000226,GO:0000278,GO:0000281,GO:0000910,GO:0000911,GO:0000912,GO:0000914,GO:0001932,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005819,GO:0005856,GO:0005911,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007275,GO:0007349,GO:0007399,GO:0008017,GO:0008092,GO:0008150,GO:0009506,GO:0009524,GO:0009555,GO:0009556,GO:0009574,GO:0009653,GO:0009966,GO:0009987,GO:0010245,GO:0010342,GO:0010646,GO:0010975,GO:0015630,GO:0015631,GO:0016043,GO:0019220,GO:0019222,GO:0019953,GO:0022008,GO:0022402,GO:0022414,GO:0022607,GO:0023051,GO:0030054,GO:0030154,GO:0030334,GO:0031323,GO:0031344,GO:0031399,GO:0032268,GO:0032501,GO:0032502,GO:0032506,GO:0032872,GO:0032879,GO:0034293,GO:0040012,GO:0042325,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043408,GO:0043934,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045595,GO:0045664,GO:0046328,GO:0048229,GO:0048236,GO:0048583,GO:0048646,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051171,GO:0051174,GO:0051239,GO:0051246,GO:0051270,GO:0051301,GO:0051321,GO:0051704,GO:0051960,GO:0055044,GO:0060255,GO:0060284,GO:0061640,GO:0065007,GO:0070302,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090036,GO:0120035,GO:1900744,GO:1902407,GO:1902410,GO:1902531,GO:1903046,GO:1903047,GO:2000026,GO:2000145,GO:2001222 2.7.11.1 0.0004192 53.0
YHH1_k127_8987297_0 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 545.0
YHH1_k127_8987297_1 UMP kinase activity K00947,K09903 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000004187 209.0
YHH1_k127_8987297_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000001389 53.0
YHH1_k127_8995490_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000002186 203.0
YHH1_k127_8995490_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000005767 138.0
YHH1_k127_8995589_0 amino acid K16263 - - 0.000000000000000000000000000000001633 148.0
YHH1_k127_8995589_1 Putative diphthamide synthesis protein K07561 - 2.5.1.108 0.00000000000005628 76.0
YHH1_k127_9008423_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.662e-221 702.0
YHH1_k127_9008423_1 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000003845 127.0
YHH1_k127_9008423_2 - - - - 0.0000000000000000000001939 113.0
YHH1_k127_9008423_3 protein serine/threonine kinase activity - - - 0.0001005 55.0
YHH1_k127_9014405_0 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000679 177.0
YHH1_k127_9014405_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001626 161.0
YHH1_k127_9014405_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000001439 158.0
YHH1_k127_9014405_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000003799 144.0
YHH1_k127_9014405_4 Sugar-specific transcriptional regulator TrmB - - - 0.00006128 52.0
YHH1_k127_9020842_0 phosphatidylinositol metabolic process - - - 0.000000000003154 79.0
YHH1_k127_9040330_0 N-acetylmuramoyl-L-alanine amidase K01447,K11066 - 3.5.1.28 0.000000000002775 76.0
YHH1_k127_9129164_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000008032 244.0
YHH1_k127_9129164_1 PFAM chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000005011 82.0
YHH1_k127_9129164_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00003641 51.0
YHH1_k127_9145171_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 369.0
YHH1_k127_9145171_1 XAA-PRO aminopeptidase K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000006676 167.0
YHH1_k127_9145171_2 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000002505 93.0
YHH1_k127_9145171_3 Transcriptional regulator, TrmB - - - 0.0000000000003481 78.0
YHH1_k127_9145171_4 PFAM PRC-barrel domain - - - 0.00005305 49.0
YHH1_k127_9145171_5 CYTH domain K05873 - 4.6.1.1 0.00007675 52.0
YHH1_k127_9145171_6 SMART AAA ATPase K02450 - - 0.0009212 51.0
YHH1_k127_918432_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000003184 197.0
YHH1_k127_918432_1 Conserved hypothetical protein 95 K07579 - - 0.0000000000005755 71.0
YHH1_k127_9187471_0 FHA domain - - - 0.000004066 54.0
YHH1_k127_9259009_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007112 269.0
YHH1_k127_9259009_1 - - - - 0.00000000000000000000000000000000000000000000000001014 186.0
YHH1_k127_929298_0 beta-glucosidase K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 334.0
YHH1_k127_929298_1 PFAM PEGA domain - - - 0.00000000000000000007366 93.0
YHH1_k127_929298_2 Psort location Cytoplasmic, score K03686 - - 0.00009981 49.0
YHH1_k127_930784_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 361.0
YHH1_k127_930784_1 Transcriptional regulator - - - 0.00001458 51.0
YHH1_k127_9317056_0 FAD binding domain - - - 0.0000000000000000000000000000000858 138.0
YHH1_k127_9317056_1 Glycosyl transferase family 2 - - - 0.00000000000000006976 83.0
YHH1_k127_9317056_2 Phosphate uptake regulator, PhoU - - - 0.00000003072 64.0
YHH1_k127_934608_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000001443 225.0
YHH1_k127_9362370_0 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000002365 110.0
YHH1_k127_9431649_0 PFAM SCP-like extracellular - - - 0.00000000000000000000000000000000000000000000001401 173.0
YHH1_k127_9431649_1 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000003521 155.0
YHH1_k127_9431649_2 Ribosomal protein S8e K02995 - - 0.0000000000000000000000000000009303 125.0
YHH1_k127_9431649_3 PFAM zinc iron permease K16267 - - 0.000000000000000000000000004885 113.0
YHH1_k127_9431649_4 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.00002182 49.0
YHH1_k127_9543311_0 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000000000000001158 125.0
YHH1_k127_9543311_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0006987 52.0
YHH1_k127_9599695_0 DNA topoisomerase II activity K02469 - 5.99.1.3 5.868e-298 936.0
YHH1_k127_9599695_1 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000004846 203.0
YHH1_k127_9599695_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000007915 198.0
YHH1_k127_9599695_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000003546 157.0
YHH1_k127_9599695_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000006273 100.0
YHH1_k127_9599695_5 Mediates both low-affinity uptake and efflux of sugar across the membrane K15382 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008515,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015766,GO:0015770,GO:0015772,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0002844 47.0
YHH1_k127_9649785_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000004616 190.0
YHH1_k127_9649785_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000001306 92.0
YHH1_k127_9705765_0 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000174 149.0
YHH1_k127_9705765_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000001795 102.0
YHH1_k127_988538_0 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000009151 127.0
YHH1_k127_9914674_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000002248 98.0
YHH1_k127_9936390_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000003887 144.0
YHH1_k127_9936390_1 Pectate lyase - - - 0.0000000005732 72.0
YHH1_k127_9936390_2 protein linear deubiquitination K08601 GO:0001775,GO:0001817,GO:0001818,GO:0001959,GO:0002218,GO:0002221,GO:0002253,GO:0002360,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002696,GO:0002753,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003824,GO:0004843,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0006355,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007154,GO:0007162,GO:0007165,GO:0007275,GO:0007346,GO:0007568,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008270,GO:0008340,GO:0009605,GO:0009607,GO:0009617,GO:0009889,GO:0009898,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010259,GO:0010468,GO:0010556,GO:0010646,GO:0010647,GO:0010648,GO:0010803,GO:0010941,GO:0010942,GO:0012501,GO:0015630,GO:0016020,GO:0016043,GO:0016579,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0019783,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022408,GO:0022409,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030097,GO:0030098,GO:0030111,GO:0030154,GO:0030155,GO:0030178,GO:0030217,GO:0030522,GO:0031098,GO:0031234,GO:0031323,GO:0031326,GO:0031344,GO:0031347,GO:0031349,GO:0032088,GO:0032479,GO:0032480,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032886,GO:0033043,GO:0033554,GO:0035556,GO:0035872,GO:0036064,GO:0036211,GO:0036459,GO:0042110,GO:0042592,GO:0042742,GO:0042981,GO:0042995,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043368,GO:0043369,GO:0043393,GO:0043412,GO:0043433,GO:0043933,GO:0044085,GO:0044087,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045058,GO:0045087,GO:0045088,GO:0045089,GO:0045165,GO:0045321,GO:0045577,GO:0045580,GO:0045581,GO:0045582,GO:0045595,GO:0045596,GO:0045597,GO:0045619,GO:0045620,GO:0045621,GO:0045785,GO:0046649,GO:0046872,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050854,GO:0050856,GO:0050857,GO:0050862,GO:0050863,GO:0050864,GO:0050865,GO:0050866,GO:0050867,GO:0050868,GO:0050870,GO:0050896,GO:0051090,GO:0051093,GO:0051094,GO:0051098,GO:0051128,GO:0051171,GO:0051239,GO:0051240,GO:0051241,GO:0051249,GO:0051250,GO:0051251,GO:0051252,GO:0051493,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055088,GO:0055090,GO:0060255,GO:0060341,GO:0060491,GO:0060759,GO:0060828,GO:0061578,GO:0061815,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070064,GO:0070265,GO:0070266,GO:0070423,GO:0070507,GO:0070536,GO:0070646,GO:0070647,GO:0071108,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0090090,GO:0097300,GO:0097343,GO:0097542,GO:0098542,GO:0098552,GO:0098562,GO:0101005,GO:0120025,GO:0120032,GO:0120035,GO:0120038,GO:0140096,GO:1901026,GO:1901222,GO:1901223,GO:1901564,GO:1902017,GO:1902105,GO:1902106,GO:1902107,GO:1902115,GO:1902531,GO:1902532,GO:1903037,GO:1903038,GO:1903039,GO:1903506,GO:1903706,GO:1903707,GO:1903708,GO:1903827,GO:1903829,GO:1990108,GO:1990380,GO:2000026,GO:2000112,GO:2001141,GO:2001233,GO:2001235,GO:2001236,GO:2001238,GO:2001242 3.4.19.12 0.0006013 53.0
YHH1_k127_9962140_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000006118 190.0
YHH1_k127_9962140_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000001437 105.0
YHH1_k127_9973298_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 497.0
YHH1_k127_9973298_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
YHH1_k127_9973298_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000001681 131.0
YHH1_k127_9983899_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000436 235.0
YHH1_k127_9983899_1 type II secretion K07333 - - 0.000000000000002894 85.0
YHH1_k127_9983899_2 Type II secretion system (T2SS), protein F K12510 - - 0.00000001063 66.0
YHH1_k127_9987611_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000007992 119.0
YHH1_k127_9987611_1 Bacterial PH domain - - - 0.0000006057 59.0
YHH1_k127_9987611_2 Ethanolamine utilisation K04030 - - 0.000393 48.0
YHH1_k127_9999404_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 542.0